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Vol. 8. Issue 2.
Pages 131-138 (March - April 2002)
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Vol. 8. Issue 2.
Pages 131-138 (March - April 2002)
ARTIGO ORIGINAL/ORIGINAL ARTICLE
Open Access
Metastização pulmonar de neoplasia da mama
Breast cancer and lung metastasis
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Jorge Dionísio1, Teresa Almodôvar2, Dina Matias2, Duro da Costa3
1 Assistente Hospitalar de Pneumologia
2 Assistente Graduado de Pneumologia
3 Chefe de Serviço de Pneumologia
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RESUMO

Para caracterizar os doentes com metastização pulmonar de neoplasia da mama, procedemos a um estudo retrospectivo dos processos de 129 doentes referenciados à Unidade de Pneumologia entre Julho de 1990 e Janeiro de 2000.

Foi considerada a existência de metastização pulmonar em 89 casos.

Avaliámos as manifestações clínicas apresentadas, o intervalo de tempo até ao diagnóstico de metastização pulmonar, os aspectos radiológicos, endoscópicos, as terapêuticas efectuadas e a sobrevida.

O intervalo médio entre o diagnóstico da neoplasia da mama e o diagnóstico de metastização pulmonar foi de 81,9±5,7 meses. Os sintomas respiratórios foram referidos em 83,1% dos doentes. O padrão radiológico mais comum foi a presença de massas ou nódulos pulmonares (66,3%). Foram observadas 49 com sinais directos de neoplasia na broncofibroscopia. Em 47 os aspectos anatomopatológicos encontrados foram compatíveis com metastização endobrônquica de tumor da mama

O tratamento mais frequentemente utilizado após o diagnóstico de metástase pulmonar foi a quimioterapia, em 60,2% dos casos.

Após o diagnóstico de metastização, a sobrevida mediana foi de 20,1 meses, com 63,4% dos doentes vivos ao fim de 1 ano.

Nos doentes com carcinoma da mama e suspeita de metastização verificámos um grande intervalo livre entre o diagnóstico do tumor da mama e o aparecimento de metastização. Os sintomas respiratórios tra-duziram a grande frequência de envolvimento endobrônquico. O diagnóstico anatomopatológico de metastização pulmonar foi obtido em 52,8% dos doentes. A terapêutica mais utilizada após diagnóstico de metastização foi a quimioterapia e a sobrevida ao ano foi de 63,4%.

REV PORT PNEUMOL 2002; VIII (2):

Palavras-Chave:
Neoplasia da mama
metástases pulmonares
envolvimento endobrônquico
ABSTRACT

We performed a retrospective study of 129 patients observed in Pneumology unit between July 1990 and January 2000 to evaluate the clinical, radiological and endoscopic patterns as well as the clinical evolution of patients with lung metastasis from breast cancer.

We obtained diagnosis of lung metastasis in 89 patients.

The mean time between diagnosis of breast cancer and lung metastasis was 81.9±5.7months. Respiratory complaints were present in 83.1% of patients. Tumoral mass or nodules were the most frequent radiological patterns (66.3%). In 49 patients, broncoscopy revealed endobronchial tumor. Histopathological findings confirmed lung metastasis from breast cancer in 47 patients.

After diagnosis, 60.2% of patients were submitted to chemotherapy. Median survival was 20.1months after lung metastasis diagnosis, and 63.4% were alive after the first year.

To conclude, a long interval between breast cancer diagnosis and lung metastasis were observed. Respiratory symptoms were frequent, as well as endobronchial involvement. Histopathological confirmation of metastasis was obtained in 52.8% of patients. Most of them were submitted to chemotherapy and 63.4% survived one year.

REV PORT PNEUMOL 2002; VIII (2):

Key-words:
Breast cancer
lung metastasis
endobronchial involvment
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Copyright © 2002. Sociedade Portuguesa de Pneumologia/SPP
Pulmonology
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