Journal Information
Vol. 2. Issue 6.
Pages 403-407 (November - December 1996)
Share
Share
Download PDF
More article options
Vol. 2. Issue 6.
Pages 403-407 (November - December 1996)
ARTIGO ORIGINAL
Open Access
Pesquisa de infecção micobacteriana em hemoculturas de doentes com SIDA, usando o sistema BACTEC 460TB
Visits
5673
Emília Prieto(1), Teresa Pacheco(2), Miguel Viveiros(1), Rosário Bettencourt(1), Laura Brum(1), Filomena Exposto(1)
(1) Departamento de Microbiologia do Instituto de Higiene e Medicina Tropical/ Universidade Nova de Lisboa (Directora - Professora Doutora Wanda F. Canas Ferreira)
(2) Serviço de Patologia Clínca do Hospital Egas Moniz
This item has received

Under a Creative Commons license
Article information
RESUMO

Nos doentes em estndios terminais da infecção por VIH (Virus da Imunodeficiência Humana) são comuns as infecções a micobactérias. O objectivo deste estudo foi avaliar a prevalência de disseminação micobacteriana nestes doentes, por hemocultura e/ou mielocultura, usando o meio BACTEC 13A® para o sistema radiométrico BACTEC 460TB, indicado para o isolamento directo de micobactérias a partir de amostras de sangue. Procedemos a hemoculturas e/ou mieloculturas em 811 doentes, obtendo-se 7,3% de isolamentos numa única amostra por doente. Determinou-se uma prevalência de 5% de lulare causadores de infecção com disseminação hematogénea. De entre os isolados de Mycobacterium tuberculosis 1,4% de Mycobacterium avium-intracel-lalare causadores de infecção com disseminação hematogénea. De entre os isolados de Mycobacterium tuberculosis 31, 4% destes apresentam-se como estirpes multir resistentes.

Palovras-chave:
Micobactérias
Hemocultura
Detecção-radiométrica
SIDA
ABSTRACT

This study evaluates the prevalency of hematogenous dissemination of mycobacteria in 811 AIDS patients. One blood or bone marrow sample was collected for direct inoculation of the BACTEC 13A radiometric broth (Becton Dickinson Diagnostic Instrument Systems, Towson, USA). There were 7,3%. positive cultures (59 patients) with 11 (1,4%) Mycobacterium avium-intracellulare isolates and 39 (5%) Mycobacterium tuberculosis isolates from which 11 (31,4%) were multidrug-resistant strains.

Key-words:
Mycobacteria
Blood culture
Rodiometric-detection
AIDS
Full text is only aviable in PDF
BIBLIOGRAFIA
[1.]
Centers of Disease Control.
Tuberculosis and human immunodeficiency virus infection: recommendations of the Advisory Council for the Elimination on Tuberculosis (ACET).
MMWR, 38 (1989), pp. 236-238
[2.]
Centers of Disease Control.
Tuberculosis and AIDS- Connecticut.
MMWR, 36 (1987), pp. 133-142
[3.]
R. Shafer, R. Goldberg, M. Sierra, A. Glatt.
Frequency of Mycobacterium tuberculosis bacteremia in patients in an area endemic for AIDS Am.
Rev. Resp. Dis., 140 (1989), pp. 1611-1613
[4.]
L. Young, C. Inderlied, O. Bhrlin, M. Gottlieb.
Mycobacterial infections in AIDS patients, with emphasis on the Mycobacterium avium complex.
Rev. Inf. Dis, 8 (1986), pp. 1024-1033
[5.]
B. Wasilauskas, R. Morrel Jr..
Inhibibitory effect of the Isolator blood culture system on growth of Mycobacterium avium-intracellulare.
J Clin. Microbiol, 32 (1994), pp. 654-657
[6.]
C. Strand, C. Epstein, S. Verzosa, E. Effatt, P. Hormozi, S. Siddiqi.
Evaluation of a new blood culture medium for mycobactéria.
Am. J. Clin. Path., 91 (1989), pp. 316-318
[7.]
Siddiqi S., Bactec T.B. System Product and procedure manual. Becton Dickinson Diagnonstic Instrument Systems, Towson, USA.
[8.]
Centers Of Disease Control.
Initial therapy for Tuberculosis in the era of multidrug resistance: recomendations of the Advisory Council for the Elimination of Tuberculosis (ACET).
MMWR, 42 (1993), pp. 1-8
[9.]
C. Von Reyen, R. Arbeit, A. Tosteson, M. Ristola, T. Barber, R. Wadell, C. Sox, R. Brindle, C. Gilks, A. Ranki, C. Bartholomew, J. Edwards, J. Falkinhamiii, G. O'Connor.
The international epidemiology of disseminated Mycobacterium avium complex infection in AIDS.
AIDS, 10 (1996), pp. 1025-1032
[10.]
S. Nightingale, L. Byrd, P. Southern, J. Jockusch, S. Cal, B. Wynne.
Incidence of Mycobacteriumavium-intracellulare complex bacteremia in human imunodeficiency virus-positive patients.
J. Inf. Dis, 165 (1992), pp. 1082-1085
[11.]
Direcção Geral de Saúde.
Tuberculose em Portugal, (1994),
Copyright © 1996. Sociedade Portuguesa de Pneumologia/SPP
Pulmonology
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?