Journal Information
Vol. 16. Issue 2.
Pages 331-337 (March - April 2010)
Share
Share
Download PDF
More article options
Vol. 16. Issue 2.
Pages 331-337 (March - April 2010)
Caso Clínico/Case Report
Open Access
Tumor de células gigantes de fémur distal com metástases pulmonares
Giant cell tumour of distal femur with pulmonary metastases
Visits
5624
Nicolas S Lazaretti1, Viviane Weiller Dallagasperina2, Rodrigo Ughini Villaroel1, Luis Alberto Schlittler1
1 Médico Oncologista Clínico do Hospital da Cidade
2 Académica da Faculdade de Medicina da Universidade de Passo Fundo
This item has received

Under a Creative Commons license
Article information
Resumo

O tumor de células gigantes é uma lesão óssea primária benigna que acomete a epífise de ossos longos, com maior incidência na terceira e quarta décadas de vida, mas que pode apresentar comportamento de um tumor maligno, com metástases à distância. Até dez por cento dos doentes podem apresentar metástases à distância, principalmente para o pulmão, geralmente acompanhadas de recidiva no local primário. O tratamento do tumor primário é a ampla ressecção cirúrgica. Os autores relatam o caso de um doente com 35 anos com metástases pulmonares 21 meses após ter realizado curetagem de tumor de células gigantes em fémur distal.

Rev Port Pneumol 2010; XVI (2): 331-337

Palavras-chave:
Tumor de células gigantes
neoplasias ósseas
metástases pulmonares
Abstract

Gian cell is normally a benign primary skeletal lesion located in the epiphysis of the long bones. It is more frequente in the third and fourth decades of life but can exhibit the behaviour of a malignant tumour with distal metatasis. Up to 10% of patients present distal metatasis, usually in the lung, and it is concomitant to recurrence in the primary site. The treatment of primary tumour is extensive surgical resection. We report a case of a 35-year-old patient with lung metatases 21 months after curettage of giant cell tumour in distal femur.

Rev Port Pneumol 2010; XVI (2): 331-337

Key-words:
Giant cell tumor
bone neoplasm
pulmonary metastases
Full text is only aviable in PDF
Bibliografia
[1.]
M.N. Sayed, S. Kondekar, S. Jaiswal, D. Rasalkar, S. Agrawal.
Giant cell tumor of the talus with pulmonary metastasis – Seven years follow up.
The Foot, 16 (2006), pp. 107-111
[2.]
M.N. Sayed, et al.
Giant cell tumor of talus, a case report of rare site.
European Journal of Radiology Extra, 61 (2007), pp. 73-75
[3.]
M. Balke, L. Schremper, C. Gebert, H. Ahrens, A. Streitbuerger, G. Koehler, et al.
Giant cell tumor of bone: treatment and outcome of 214 cases.
J Cancer Res Clin Oncol, (2008),
[4.]
P. Saiz, W. Virkus, P. Piasecki, A. Templeton, S. Shott, S. Gitelis.
Results of giant cell tumor of bone treated with intralesional excision.
Clin Orthop, 424 (2004), pp. 221-226
[5.]
S. Wakitani, K. Imoto, M. Saito, T. Yamamoto, H. Kawabata.
A case report: reconstruction of a damaged knee following treatment of giant cell tumor of the proximal tibia with cryosurgery and cementation.
Osteoarthritis Cartilage, 10 (2002), pp. 402-407
[6.]
W. Zhen, H. Yaotian, L. Songjian, L. Ge, W. Qingliang.
Giant-cell tumour of bone. The long-term results of treatment by curettage and bone graft.
J Bone Joint Surg Br, 86 (2004), pp. 212-216
[7.]
M. Balke, H. Ahrens, A. Streitbuerger, G. Koehler, W. Winkelmann, G. Gosheger, et al.
Treatment options for recurrent giant cell tumors of bone.
J Cancer Res Clin Oncol, (2008),
[8.]
F. Malek, P. Krueger, Z.N. Hatmi, A.A. Malayeri, H. Faezipour, R.J. O’Donnell.
Local control of long bone giant cell tumour using curettage, burring and bone grafting without adjuvant therapy.
Int Orthop, 30 (2006), pp. 495-498
[9.]
K.A. Siebenrock, K.K. Unni, M.G. Rock.
Giant-cell tumour of bone metastasising to the lungs.
A long-term follow-up. J Bone Joint Surg Br, 80 (1998), pp. 43-47
[10.]
E.J. Heffernan, P.J. O’Sullivan, M. Adibeig, L.J. Louis, A.G. Ryana, T.O. Neilsen, et al.
Primary malignant transformation of giant cell tumor of bone.
European Journal of Radiology Extra, 62 (2007), pp. 89-93
[11.]
M. Werner.
Giant cell tumour of bone: morphological, biological and histogenetical aspects.
Int Orthop, 30 (2006), pp. 484-489
Copyright © 2010. Sociedade Portuguesa de Pneumologia/SPP
Pulmonology
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?