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        "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Objectivos&#58;</span> Comparar os efeitos da asma e da DPOC na qualidade de vida dos doentes avaliados pelo Saint George Respiratory Questionnaire &#40;SGRQ&#41; atrav&#233;s de correla&#231;&#245;es entre as vari&#225;veis e os dom&#237;nios e a pontua&#231;&#227;o total&#46; <span class="elsevierStyleBold">M&#233;todos&#58;</span> Estudo transversal entre Outubro de 2008 a Mar&#231;o de 2009 com 75 adultos das consultas de ambulat&#243;rio do Hospital Universit&#225;rio de Salamanca&#44; Espanha&#46; Depois de informar os objectivos do estudo e os aspectos &#233;ticos&#44; foi preenchido um formul&#225;rio com os dados cl&#237;nicos e sociodemogr&#225;ficos e&#44; em seguida&#44; aplicada a vers&#227;o espanhola do SGRQ&#46; Para a an&#225;lise estat&#237;stica fui utilizada o pacote estat&#237;stico Stadistics SPSS vers&#227;o 17&#46;0&#46; <span class="elsevierStyleBold">Resultados&#58;</span> 65&#44;3&#37; eram homens e 34&#44;7&#37; mulheres com idade m&#233;dia de 60&#44;4 anos&#59; 68&#37; tinham diagn&#243;stico de asma e 30&#44;7&#37; de DPOC&#46; Foram encontradas diferen&#231;as estatisticamente significativas &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41; entre o diagn&#243;stico e o dom&#237;nio actividade&#59; e nenhuma entre o sexo&#44; o facto de ser fumador&#44; ex-fumador ou hipertenso com os dois dom&#237;nios&#46; Os n&#237;veis socioecon&#243;micos relacionam-se de forma inversa e significativa &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;038&#41; com a pontua&#231;&#227;o total&#46; Foram obtidas diferen&#231;as estatisticamente significativas entre a idade e os dom&#237;nios actividade &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;01&#41; e impacto &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41; e a pontua&#231;&#227;o total do SGRQ &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;01&#41;&#46; O VEF1VEMS correlacionou-se apenas com o dom&#237;nio actividade &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;01&#41; e com a pontua&#231;&#227;o total do question&#225;rio &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;01&#41;&#46; <span class="elsevierStyleBold">Conclus&#245;es&#58;</span> Nenhuma vari&#225;vel se correlacionou com todos os dom&#237;nios e a pontua&#231;&#227;o total do instrumento e algumas n&#227;o apresentaram diferen&#231;a estatisticamente significativa&#46;</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010&#59; XVI &#40;4&#41;&#58; 543-558</span></p></span>"
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        "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Aims&#58;</span> To compare the effects of asthma and chronic obstructive pulmonary disease &#40;COPD&#41; on the quality of life of patients evaluated using the Saint George Respiratory Questionnaire &#40;SGRQ&#41; through correlating the variables&#44; domains and total score&#46; <span class="elsevierStyleBold">Methods&#58;</span> A cross-sectional study from October 2008 to March 2009 with 75 adult outpatients at the University Hospital of Salamanca&#44; Spain&#46; Patients provided their clinical and socio-demographical data after being informed of the study&#8217;s aims and ethical aspects&#46; The Spanish version of the SGRQ and the statistical package Statistics SPSS version 17&#46;0 were used for statistical analysis&#46; <span class="elsevierStyleBold">Results&#58;</span> 65&#46;3&#37; were male and 34&#46;7&#37; female with mean age 60&#46;4<span class="elsevierStyleHsp" style=""></span>years&#46; 68&#37; had a diagnosis of asthma and 30&#46;7&#37; COPD&#46; Statistically significant differences &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05&#41; between diagnosis and the &#8216;activity&#8217; domain were found&#46; None were found between gender&#44; smoking&#44; ex-smoking or hypertension and the domains&#46; The income levels were inversely related &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;038&#41; with the total score&#46; Statistically significant differences between age and the &#8216;activity&#8217; &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41; and &#8216;impact&#8217; &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05&#41; domains and the SGRQ total score were found &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#46; The forced expiratory volume in one second &#40;FEV1&#37;pred&#41; only correlated with the &#8216;activity&#8217; domain &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41; and with the total score &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#46; <span class="elsevierStyleBold">Conclusions&#58;</span> No variable correlated with all domains and the total score of the instrument&#46; Some presented no statistically significant difference&#46;</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010&#59; XVI &#40;4&#41;&#58; 543-558</span></p></span>"
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Vol. 16. Issue 4.
Pages 543-558 (July - August 2010)
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Vol. 16. Issue 4.
Pages 543-558 (July - August 2010)
Artigo Original/Original Article
Open Access
A qualidade de vida relacionada com a saúde de doentes com doença pulmonar obstrutiva crónica e asma avaliada pelo SGRQ
The health-related quality of life of patients with chronic obstructive pulmonary disease and asthma evaluated by the SGRQ
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Juliana Maria de Sousa Pinto1,
Corresponding author
jujumsp@yahoo.com.br

Correspondência/Correspondence to: Paseo San Vicente 55-182 – Salamanca 37007
, Jacinto Ramos González2, José Ignácio Calvo Arenillas3, Ana María Martín Nogueras4, Francisco Pedro Gómez Gómez5
1 Doutoramento em “Avances en Investigación sobre Discapacidad” – Universidade de Salamanca; Bolseista MAEC-AECID, Espanha; mestrado em “Educação em Saúde” – Universidade de Fortaleza, Brasil; professora do Curso de Fisioterapia da Universidade de Fortaleza (UNIFOR), Brasil/PhD in Avances en Investigación sobre Discapacidad/Advances in Research into Disability – Universidade de Salamanca, Spain; MAEC-AECID scholarship holder, Spain; MsC in Educação em Saúde / Health Education – Universidade de Fortaleza, Brazil; Professor, Physiotherapy, Universidade de Fortaleza (UNIFOR), Brazil
2 Doutoramento em “Avances en Medicina Interna” pela Universidade de Salamanca; professor associado do Curso de Medicina da Universidade de Salamanca/PhD in Avances in Medicina Interna/Advances in Internal Medicine – Universidade de Salamanca, Spain; Associate Professor, Medicine, Universidade de Salamanca, Spain
3 Doutor em Medicina y Cirurgia – Universidade de Salamanca; professor catedrático da Escola de Fisioterapia da Universidade de Salamanca/M.D. Medicine and Surgery – Universidade de Salamanca, Spain; Tenured Professor, School of Physiotherapy, Universidade de Salamanca, Spain
4 Doutora pela Universidade de Salamanca; professora titular da Escola de Fisioterapia da Universidade de Salamanca/M.D. Universidade de Salamanca, Spain; Full Professor, School of Physiotherapy, Universidade de Salamanca, Spain
5 Doutor em Medicina e Cirurgia – Universidade de Salamanca/M.D. Medicine and Surgery – Universidade de Salamanca, Spain
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Resumo

Objectivos: Comparar os efeitos da asma e da DPOC na qualidade de vida dos doentes avaliados pelo Saint George Respiratory Questionnaire (SGRQ) através de correlações entre as variáveis e os domínios e a pontuação total. Métodos: Estudo transversal entre Outubro de 2008 a Março de 2009 com 75 adultos das consultas de ambulatório do Hospital Universitário de Salamanca, Espanha. Depois de informar os objectivos do estudo e os aspectos éticos, foi preenchido um formulário com os dados clínicos e sociodemográficos e, em seguida, aplicada a versão espanhola do SGRQ. Para a análise estatística fui utilizada o pacote estatístico Stadistics SPSS versão 17.0. Resultados: 65,3% eram homens e 34,7% mulheres com idade média de 60,4 anos; 68% tinham diagnóstico de asma e 30,7% de DPOC. Foram encontradas diferenças estatisticamente significativas (p<0,05) entre o diagnóstico e o domínio actividade; e nenhuma entre o sexo, o facto de ser fumador, ex-fumador ou hipertenso com os dois domínios. Os níveis socioeconómicos relacionam-se de forma inversa e significativa (p=0,038) com a pontuação total. Foram obtidas diferenças estatisticamente significativas entre a idade e os domínios actividade (p<0,01) e impacto (p<0,05) e a pontuação total do SGRQ (p<0,01). O VEF1VEMS correlacionou-se apenas com o domínio actividade (p<0,01) e com a pontuação total do questionário (p<0,01). Conclusões: Nenhuma variável se correlacionou com todos os domínios e a pontuação total do instrumento e algumas não apresentaram diferença estatisticamente significativa.

Rev Port Pneumol 2010; XVI (4): 543-558

Palavras-chave:
Qualidade de vida
doença pulmonar obstrutiva crónica
asma
Abstract

Aims: To compare the effects of asthma and chronic obstructive pulmonary disease (COPD) on the quality of life of patients evaluated using the Saint George Respiratory Questionnaire (SGRQ) through correlating the variables, domains and total score. Methods: A cross-sectional study from October 2008 to March 2009 with 75 adult outpatients at the University Hospital of Salamanca, Spain. Patients provided their clinical and socio-demographical data after being informed of the study’s aims and ethical aspects. The Spanish version of the SGRQ and the statistical package Statistics SPSS version 17.0 were used for statistical analysis. Results: 65.3% were male and 34.7% female with mean age 60.4years. 68% had a diagnosis of asthma and 30.7% COPD. Statistically significant differences (p<0.05) between diagnosis and the ‘activity’ domain were found. None were found between gender, smoking, ex-smoking or hypertension and the domains. The income levels were inversely related (p=0.038) with the total score. Statistically significant differences between age and the ‘activity’ (p<0.01) and ‘impact’ (p<0.05) domains and the SGRQ total score were found (p<0.01). The forced expiratory volume in one second (FEV1%pred) only correlated with the ‘activity’ domain (p<0.01) and with the total score (p<0.01). Conclusions: No variable correlated with all domains and the total score of the instrument. Some presented no statistically significant difference.

Rev Port Pneumol 2010; XVI (4): 543-558

Key-words:
Quality of life
chronic obstructive pulmonary disease
asthma
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Bibliografia/Bibliography
[1.]
R.A. Pauwels, K.F. Rabe.
Burden and clinical features of chronic obstructive pulmonary disease (COPD).
[2.]
C.J.L. Murray, J.Á. Salomon, C.D. Mathers, A.D. Lopez.
Summary measures of population health: concepts, ethics, measurement and applications, World Health Organization, (2002),
[3.]
World Health Organization.
Chronic diseases.
[4.]
R.A. Pauwels, A.S. Buist, P.M. Calverley, C.R. Jenkins, S.S. Hurd.
GOLD Scientific Committee. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary.
Am J Respir Crit Care Med, 163 (2001), pp. 1256-1276
[5.]
M. Cazzola, C.F. Donner, N.A. Hanania.
One hundred years of chronic obstructive pulmonary disease (COPD).
Respiratory Medicine, 101 (2007), pp. 1049-1065
[6.]
M. Masoli, D. Fabian, S. Holt, R. Beasley.
Global Initiative for Asthma (GINA) Program. The global burden of asthma: executive summary of the GINA dissemination committee report.
[7.]
B.C. Sanjuas.
Measuring quality of life: generic or specific questionnaires?.
Arch Bronconeumol, 41 (2005), pp. 107-109
[8.]
J.E. Ware.
Conceptualization and measurement of health-related quality of life: comments on an evolving field.
Arch of Phys Med and Rehab, 84 (2003), pp. 543-551
[9.]
A.M. Donald.
How Should Health-Related Quality of Life Be Assessed in Patients With COPD?.
Chest, 117 (2000), pp. 54-57
[10.]
T. Oga, K. Nishimura, M. Tsukino, S. Sato, T. Hajiro, M. Mishima.
Longitudinal deteriorations in patient reported outcomes in patients with COPD.
Respiratory Medicine, 101 (2007), pp. 146-153
[11.]
P.W. Jones, F.H. Quirk, C.M. Baveystock.
The Saint George´s Respiratory Questionnarie.
Respiratory Medicine, 85 (1991), pp. 25-31
[12.]
Dyspnea mechanisms, assessment and management: a consensus statement. American Thoracic Society.
Am J Respir Crit Care Med, 159 (1999), pp. 321-340
[13.]
M. Ferrer, J. Alonso, L. Prieto, V. Plaza, E. Monso, R. Marrades, et al.
Validity and reliability of the St George’s Respiratory Questionnaire after adaptation to a different language and culture: the Spanish example.
Eur Respir J, 9 (1996), pp. 1160-1166
[14.]
P.W. Jones.
Health status measurement in chronic obstructive pulmonary disease.
Thorax, 56 (2001), pp. 880-887
[15.]
C.R.L. Boot, J.W.J. Gulden, J.H.M.M. Vercoulen, B.H.W. Borne, K.H. Orbon, J. Rooijackers, et al.
Knowledge about asthma and COPD: associations with sick, health complaints, functional limitations, adaptation, and perceived control.
Patient Education and Counseling, 59 (2005), pp. 103-109
[16.]
W.M. Liang, J.J. Chen, C.H. Chang, H.W. Chen, S.L. Chen, L.W. Hang, et al.
An empirical comparison of the WHOQOL-BREF and the SGRQ among patients with COPD.
Qual Life Res, 17 (2008), pp. 793-800
[17.]
V. Plaza, J. Serra-Batlles, M. Ferrer, E. Morejón.
Quality of life and economic features in elderly asthmatics.
Respiration, 67 (2000), pp. 65-70
[18.]
A.D. Lopez, C.C. Murray.
The global burden of disease, 1990-2020.
Nat Med, 4 (1998), pp. 1241-1243
[19.]
M. Ferrer, C. Villasante, J. Alonso, V. Sobradillo, R. Gabriel, G. Vilagut, et al.
Interpretation of quality of life scores from the St George´s Respiratory Questionnarie.
Eur Resp J, 19 (2002), pp. 405-413
[20.]
L.M. Osman, C. Calder, R. Robertson, J.A.R. Friend, J.S. Legge, J.G. Douglas.
Symptoms, quality of life, and health service contact among young adults with mild asthma.
Am J Respir Crit Care Med, 161 (2000), pp. 498-503
[21.]
R.A. Incalzi, C. Imperiale, V. Bellia, F. Catalano, N. Scichilone, R. Pistelli, et al.
Do GOLD stages of COPD severity really correspond to differences in health status?.
Eur Respir J, 22 (2002), pp. 444-449
[22.]
R.A. Incalzi, V. Bellía, F. Catalano, N. Scichilone, C. Imperiale, S. Maggi, et al.
Evaluation of Health Outcomes in Elderly Patients with Asthma and COPD using disease-specific and generic instruments: the salute respiratoria nell´Anziano (Sa.R.A.) Study.
Chest, 120 (2001), pp. 734-742
[23.]
P.W. Jones.
Activity limitation and quality of life in COPD.
[24.]
F. Gallefoss, P.S. Bakke, P. Kjaersgaard.
Quality of life assessment after patient education in a randomized controlled study on asthma and chronic obstructive pulmonary disease.
Am J Respir Crit Care Med, 159 (1999), pp. 812-817
[25.]
E. Ståhl, A. Lindberg, S.A. Jansson, E. Rönmark, K. Svensson, F. Andersson, et al.
Health-related quality of life is related to COPD disease severity.
Health Qual Life Outcomes, 3 (2005), pp. 56
[26.]
A.R. Maille, C.J. Koning, A.H. Zwinderman, et al.
The development of the “Quality-of-life for Respiratory Illness Questionnaire (QOL-RIQ)”: a disease-specific quality-of-life questionnaire for patients with mild to moderate chronic non-specific lung disease.
Respir Med, 91 (1997), pp. 297-309
[27.]
H.A. Wijnhoven, D.M. Kriegsman, A.E. Hesselink, B.W. Penninx, M. de Haan.
Determinants of different dimensions of disease severity in asthma and COPD: pulmonary function and health-related quality of life.
Chest, 119 (2001), pp. 1034-1042
[28.]
T. Hajiro, K. Nishimura, M. Tsukino, A. Ikeda, T. Oga.
Stages of disease severity and factors that effect the health status of patients with chronic obstructive pulmonary disease.
Respiratory Medicine, 94 (2000), pp. 841-846
Copyright © 2010. Sociedade Portuguesa de Pneumologia/SPP
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