array:24 [
  "pii" => "S2173511506704249"
  "issn" => "21735115"
  "doi" => "10.1016/S2173-5115(06)70424-9"
  "estado" => "S300"
  "fechaPublicacion" => "2006-09-01"
  "aid" => "70424"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2006"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "fla"
  "cita" => "Rev Port Pneumol. 2006;12:615-20"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2659
    "formatos" => array:3 [
      "EPUB" => 197
      "HTML" => 1446
      "PDF" => 1016
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173511506704250"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70425-0"
    "estado" => "S300"
    "fechaPublicacion" => "2006-09-01"
    "aid" => "70425"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Pneumol. 2006;12:621-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3307
      "formatos" => array:3 [
        "EPUB" => 231
        "HTML" => 1849
        "PDF" => 1227
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Carcinoma pleomórfico do pulmão em doente com síndroma de Mounier-Kuhn"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "621"
          "paginaFinal" => "628"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Pleomorphic carcinoma of the lung in a patient with Mounier-Kuhn syndrome"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Daniela Ferreira, Ana Barroso, Ana Oliveira, Rosete Nogueira, Antónia Furtado, Bárbara Parente"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Daniela"
              "apellidos" => "Ferreira"
            ]
            1 => array:2 [
              "nombre" => "Ana"
              "apellidos" => "Barroso"
            ]
            2 => array:2 [
              "nombre" => "Ana"
              "apellidos" => "Oliveira"
            ]
            3 => array:2 [
              "nombre" => "Rosete"
              "apellidos" => "Nogueira"
            ]
            4 => array:2 [
              "nombre" => "Antónia"
              "apellidos" => "Furtado"
            ]
            5 => array:2 [
              "nombre" => "Bárbara"
              "apellidos" => "Parente"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704250?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000005/v1_201305151428/S2173511506704250/v1_201305151428/pt/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173511506704237"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70423-7"
    "estado" => "S300"
    "fechaPublicacion" => "2006-09-01"
    "aid" => "70423"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Pneumol. 2006;12:603-13"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4972
      "formatos" => array:3 [
        "EPUB" => 243
        "HTML" => 2658
        "PDF" => 2071
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Recomendações para diagnóstico e tratamento da tuberculose latente e activa nas doenças inflamatórias articulares candidatas a tratamento com fármacos inibidores do factor de necrose tumoral alfa"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "603"
          "paginaFinal" => "613"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Guidelines for the diagnosis and treatment of latent tuberculosis infection and active tuberculosis in patients with inflamatory joint diseases proposed for treatment with tumour necrosis factor alpha antagonists drugs"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "João Eurico Fonseca, Helena Lucas, Helena Canhão, Raquel Duarte, Maria José Santos, Miguel Villar, Augusto Faustino, Elena Raymundo"
          "autores" => array:8 [
            0 => array:2 [
              "nombre" => "João Eurico"
              "apellidos" => "Fonseca"
            ]
            1 => array:2 [
              "nombre" => "Helena"
              "apellidos" => "Lucas"
            ]
            2 => array:2 [
              "nombre" => "Helena"
              "apellidos" => "Canhão"
            ]
            3 => array:2 [
              "nombre" => "Raquel"
              "apellidos" => "Duarte"
            ]
            4 => array:2 [
              "nombre" => "Maria José"
              "apellidos" => "Santos"
            ]
            5 => array:2 [
              "nombre" => "Miguel"
              "apellidos" => "Villar"
            ]
            6 => array:2 [
              "nombre" => "Augusto"
              "apellidos" => "Faustino"
            ]
            7 => array:2 [
              "nombre" => "Elena"
              "apellidos" => "Raymundo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704237?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000005/v1_201305151428/S2173511506704237/v1_201305151428/pt/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "titulo" => "Acute fibrinous and organizing pneumonia"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "615"
        "paginaFinal" => "620"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "C. Damas, A. Morais, C.S. Moura, J.A. Marques"
        "autores" => array:4 [
          0 => array:3 [
            "nombre" => "C."
            "apellidos" => "Damas"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "A&#46;"
            "apellidos" => "Morais"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">2</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "C&#46;S&#46;"
            "apellidos" => "Moura"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">3</span>"
                "identificador" => "aff0025"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "J&#46;A&#46;"
            "apellidos" => "Marques"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">4</span>"
                "identificador" => "aff0035"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:4 [
          0 => array:3 [
            "entidad" => "Interna Complementar de Pneumologia&#44; Servi&#231;o de Pneumologia&#44; Hospital de S&#227;o Jo&#227;o&#44; EPE&#44; Porto Faculdade de Medicina da Universidade do Porto &#40;FMUP&#41;"
            "etiqueta" => "<span class="elsevierStyleSup">1</span>"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Assistente Hospitalar de Pneumologia&#44; Servi&#231;o de Pneumologia&#44; Hospital de S&#227;o Jo&#227;o&#44; EPE&#44; Porto Faculdade de Medicina da Universidade do Porto &#40;FMUP&#41;"
            "etiqueta" => "<span class="elsevierStyleSup">2</span>"
            "identificador" => "aff0015"
          ]
          2 => array:3 [
            "entidad" => "Assistente Hospitalar de Anatomia Patol&#243;gica&#44; Servi&#231;o de Pneumologia&#44; Hospital de S&#227;o Jo&#227;o&#44; EPE&#44; Porto Faculdade de Medicina da Universidade do Porto &#40;FMUP&#41;"
            "etiqueta" => "<span class="elsevierStyleSup">3</span>"
            "identificador" => "aff0025"
          ]
          3 => array:3 [
            "entidad" => "Chefe de Servi&#231;o de Pneumologia&#44; Professor Catedr&#225;tico de Pneumologia da FMUP&#44; Director do Servi&#231;o de Pneumologia"
            "etiqueta" => "<span class="elsevierStyleSup">4</span>"
            "identificador" => "aff0035"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "<span class="elsevierStyleItalic">Correspondence to</span>&#47;Correspond&#234;ncia&#58; Travessa Fernando Namora&#44; 48 5&#46;&#176; Esq&#46;&#44; 4425 Pedrou&#231;os &#8211; Maia&#44; Portugal&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Pneumonia aguda fibrinosa e organizante"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2006-03-28"
    "fechaAceptado" => "2006-05-26"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key-words"
          "identificador" => "xpalclavsec158882"
          "palabras" => array:2 [
            0 => "AFOP"
            1 => "organizing pneumonia"
          ]
        ]
      ]
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec158881"
          "palabras" => array:2 [
            0 => "AFOP"
            1 => "pneumonia organizativa"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">The term Acute Fibrinous and Organizing Pneumonia &#40;AFOP&#41; has been proposed by Beasley <span class="elsevierStyleItalic">et al</span> for cases that not fit into the histopathologic criteria of the recognized entities described as acute or subacute clinical presentations&#46; The presence of intra-alveolar fibrin in the form of fibrin &#8216;balls&#8217; and organizing pneumonia with patchy distribution are the main histological features of this entity&#46; We describe the case of a male patient with the diagnostic of AFOP made by surgical lung biopsy&#46; He had a subacute presentation of symptoms consisting of productive cough&#44; chest pain and fever&#46; Bilateral infiltrates with patchy and diffuse distribution were the predominant features in his chest HRCT scan&#46; The patient had a good clinical course after a treatment with prednisone and cyclophosphamide&#46; Our hope in reporting this case study is to add some more data to the discussion of this new entity&#46;</p>"
      ]
      "pt" => array:2 [
        "titulo" => "Resumo"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A designa&#231;&#227;o <span class="elsevierStyleItalic">acute fibrinous and organizing pneumonia &#40;AFOP&#41;</span> foi proposta por Beasley <span class="elsevierStyleItalic">et al</span> para os casos em que as caracter&#237;sticas histopatol&#243;gicas das les&#245;es n&#227;o se enquadravam em outras situa&#231;&#245;es cl&#237;nicas &#40;agudas ou subagudas&#41; conhecidas&#46; A presen&#231;a de fibrina intra alveolar e de pneumonia organizativa&#44; com distribui&#231;&#227;o difusa&#44; &#233; a principal altera&#231;&#227;o histol&#243;gica associada a esta entidade&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Os autores descrevem o caso de um doente do sexo masculino&#44; com o diagn&#243;stico de AFOP&#44; por bi&#243;psia pulmonar cir&#250;rgica&#46; O doente teve uma apresenta&#231;&#227;o subaguda&#44; apresentando por queixas principais tosse&#44; dor tor&#225;cica e febre&#46; TAC tor&#225;cica mostrou infiltrados bilaterais&#44; difusos&#46; Ap&#243;s in&#237;cio de corticoterapia sist&#233;mica e ciclofosfamida&#44; o doente apresentou melhoria cl&#237;nica significativa&#46; Ao elaborar este caso&#44; os autores esperam acrescentar mais alguns dados sobre esta nova entidade&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliography"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:3 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acute Fibrinous and Organizing Pneumonia&#58; a histologic pattern of lung injury and possible variant of difuse alveolar damage"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46;B&#46; Beasley"
                            1 => "T&#46;J&#46; Franks"
                            2 => "J&#46;R&#46; Galvin"
                            3 => "B&#46; Gochuico"
                            4 => "W&#46;D&#46; Travis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1043/0003-9985(2002)126<1064:AFAOP>2.0.CO;2"
                      "Revista" => array:7 [
                        "tituloSerie" => "Archives of Pathology and Laboratory Medicine"
                        "fecha" => "2002"
                        "volumen" => "126"
                        "numero" => "9"
                        "paginaInicial" => "1064"
                        "paginaFinal" => "1070"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12204055"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Organizing Pneumonia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46;F&#46; Cordier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "2002"
                        "volumen" => "55"
                        "paginaInicial" => "318"
                        "paginaFinal" => "328"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10722773"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchiolar Disorders"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;H&#46; Ryu"
                            1 => "J&#46;L&#46; Myers"
                            2 => "S&#46;J&#46; Swensen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Resp and Crit Care Med"
                        "fecha" => "2003"
                        "volumen" => "168"
                        "paginaInicial" => "1277"
                        "paginaFinal" => "2129"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735115/0000001200000005/v1_201305151428/S2173511506704249/v1_201305151428/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9550"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case Report&#47;Caso Cl&#237;nico"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001200000005/v1_201305151428/S2173511506704249/v1_201305151428/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704249?idApp=UINPBA00004E"
]
Share
Journal Information
Vol. 12. Issue 5.
Pages 615-620 (September - October 2006)
Share
Share
Download PDF
More article options
Vol. 12. Issue 5.
Pages 615-620 (September - October 2006)
Full text access
Acute fibrinous and organizing pneumonia
Pneumonia aguda fibrinosa e organizante
Visits
1357
C. Damas1,
, A. Morais2, C.S. Moura3, J.A. Marques4
1 Interna Complementar de Pneumologia, Serviço de Pneumologia, Hospital de São João, EPE, Porto Faculdade de Medicina da Universidade do Porto (FMUP)
2 Assistente Hospitalar de Pneumologia, Serviço de Pneumologia, Hospital de São João, EPE, Porto Faculdade de Medicina da Universidade do Porto (FMUP)
3 Assistente Hospitalar de Anatomia Patológica, Serviço de Pneumologia, Hospital de São João, EPE, Porto Faculdade de Medicina da Universidade do Porto (FMUP)
4 Chefe de Serviço de Pneumologia, Professor Catedrático de Pneumologia da FMUP, Director do Serviço de Pneumologia
This item has received
Article information
Abstract

The term Acute Fibrinous and Organizing Pneumonia (AFOP) has been proposed by Beasley et al for cases that not fit into the histopathologic criteria of the recognized entities described as acute or subacute clinical presentations. The presence of intra-alveolar fibrin in the form of fibrin ‘balls’ and organizing pneumonia with patchy distribution are the main histological features of this entity. We describe the case of a male patient with the diagnostic of AFOP made by surgical lung biopsy. He had a subacute presentation of symptoms consisting of productive cough, chest pain and fever. Bilateral infiltrates with patchy and diffuse distribution were the predominant features in his chest HRCT scan. The patient had a good clinical course after a treatment with prednisone and cyclophosphamide. Our hope in reporting this case study is to add some more data to the discussion of this new entity.

Key-words:
AFOP
organizing pneumonia
Resumo

A designação acute fibrinous and organizing pneumonia (AFOP) foi proposta por Beasley et al para os casos em que as características histopatológicas das lesões não se enquadravam em outras situações clínicas (agudas ou subagudas) conhecidas. A presença de fibrina intra alveolar e de pneumonia organizativa, com distribuição difusa, é a principal alteração histológica associada a esta entidade.

Os autores descrevem o caso de um doente do sexo masculino, com o diagnóstico de AFOP, por biópsia pulmonar cirúrgica. O doente teve uma apresentação subaguda, apresentando por queixas principais tosse, dor torácica e febre. TAC torácica mostrou infiltrados bilaterais, difusos. Após início de corticoterapia sistémica e ciclofosfamida, o doente apresentou melhoria clínica significativa. Ao elaborar este caso, os autores esperam acrescentar mais alguns dados sobre esta nova entidade.

Palavras-chave:
AFOP
pneumonia organizativa
Full text is only aviable in PDF
Bibliography
[1.]
M.B. Beasley, T.J. Franks, J.R. Galvin, B. Gochuico, W.D. Travis.
Acute Fibrinous and Organizing Pneumonia: a histologic pattern of lung injury and possible variant of difuse alveolar damage.
Archives of Pathology and Laboratory Medicine, 126 (2002), pp. 1064-1070
[2.]
J.F. Cordier.
Organizing Pneumonia.
Thorax, 55 (2002), pp. 318-328
[3.]
J.H. Ryu, J.L. Myers, S.J. Swensen.
Bronchiolar Disorders.
Am J Resp and Crit Care Med, 168 (2003), pp. 1277-2129
Copyright © 2006. Sociedade Portuguesa de Pneumologia
Download PDF
Pulmonology
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?