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Vol. 15. Issue 1.
Pages 101-107 (January - February 2009)
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Vol. 15. Issue 1.
Pages 101-107 (January - February 2009)
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Carcinoma adenóide quístico recorrente. Revisão a propósito de um caso clínico
Recurrent adenoid cystic carcinoma. Review based on a case report
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Nicole Murinello1,8, M Emília Vitorino2,8, Cristina Matos3,8, José Manuel Correia3,8, Manuela Lima4,8, Pedro Baptista5,8, José Sena Lino6,8, Fernando Nogueira7,8
1 Interna do Internato Complementar de Pneumologia
2 Interna do Internato Complementar de Anatomia Patológica
3 Assistente Hospitalar Graduado de Pneumologia
4 Assistente Hospitalar de Anatomia Patológica
5 Assistente Hospitalar Graduado de Cirurgia Torácica
6 Chefe de Serviço em Cirurgia Torácica
7 Chefe de Serviço em Pneumologia, Director de Serviço
8 Hospital Egas Moniz, Centro Hospitalar de Lisboa Ocidental
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Resumo

O carcinoma adenóide quístico é uma neoplasia epitelial maligna de origem glandular, ocorrendo nas glândulas mamárias, salivares e raramente no pulmão, onde é responsável por 0,2% dos tumores. Embora raro, é o tumor de “tipo glândula salivar” mais comum ao nível do tracto respiratório.

Estes tumores apresentam um crescimento lento e curso clínico prolongado, caracterizando-se pela natureza infiltrativa, com tendência para a recorrência local tardia.

Os autores apresentam o caso de uma mulher com carcinoma adenóide quístico do pulmão diagnosticado na sequência de investigação de nódulo do pulmão submetida a ressecção cirúrgica com intuito curativo, cujo follow-up documentou recidiva local tardia 9 anos após a ressecção.

O presente caso vem realçar a necessidade de vigilância prolongada, dado o potencial de recidiva local tardia deste tipo de tumor. O artigo revê aspectos clínicos e patológicos do carcinoma adenóide quístico do pulmão e discute opções terapêuticas, nomeadamente de prevenção da recidiva, à luz dos conhecimentos actuais.

Palavras-chave:
Carcinoma adenóide quístico
pulmão
Abstract

The adenoid cystic carcinoma is a malignant epithelial glandular type neoplasia, occurring frequently in the salivary and mammary glands, and rarely in the lung, and is responsible for 0.2% of lung tumours.

These tumours present a slow growth and prolonged clinical course, and are characterised by their infiltrative nature and tendency towards late local recurrence.

The authors present a case of a woman with adenoid cystic lung carcinoma diagnosed after investigation of a lung nodule, submitted to surgical resection with curative intention, whose follow-up identified late recurrence, 9 years after surgery.

The present case emphasises the need for a prolonged surveillance, due to the potential late recurrence of this kind of tumour. The article reviews clinical and pathological features of lung adenoid cystic carcinoma, as well as therapeutic options, namely for prevention of recurrence.

Key-words:
Adenoid cystic carcinoma
lung
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Copyright © 2009. Sociedade Portuguesa de Pneumologia
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