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Vol. 16. Issue 1.
Pages 157-161 (January - February 2010)
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Vol. 16. Issue 1.
Pages 157-161 (January - February 2010)
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Enfisema bolhoso associado a consumo de drogas
Bullous emphysema associated with drug abuse
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Sandra Figueiredo1,3, Gabriela Fernandes2,3, António Morais2,3
1 Interna Complementar de Pneumologia/Resident, Pulmonology
2 Assistente Hospitalar de Pneumologia/Consultant, Pulmonology
3 Serviço de Pneumologia do Hospital de São João, Porto
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Resumo

O enfisema bolhoso é caracterizado pelo aumento dos espaços aéreos distais ao bronquíolo terminal com perda das paredes alveolares. Várias etiologias têm sido descritas, nomeadamente a deficiência de alfa1-antitripsina e o consumo de tabaco. À excepção da deficiência de alfa1-antitripsina, alguns casos de enfisema bolhoso no jovem continuam sem etiologia conhecida. Têm sido descritos alguns casos associados a consumo de drogas. O tabagismo associado ao consumo de drogas possivelmente criará as condições para o desenvolvimento de bolhas, com particular exuberância pelos lobos superiores. Os autores descrevem dois casos clínicos de doentes jovens, com história de consumo de drogas inaladas e enfisema bolhoso.

Palavras-chave:
Enfisema bolhoso
drogas inaladas
Abstract

Bullous emphysema is characterized by permanent enlargement of airspaces distal to the terminal bronchiole accompanied by destruction of alveolar walls. Several aetiologies have been described, namely deficiency of α1-antitrypsin and the consumption of tobacco. With the exception of the deficiency of α1-antitrypsin, some cases of bullous emphysema in the young adult continue without known aetiology. Some cases of bullous emphysema have been described, emphasising the relationship between the disease and drug consumption. The association possibly creates the conditions for the development of large lung bullae, with particular exuberance for the superior lobes. The authors describe two clinical cases of young patients, with history of consumption of smoked subs tance abuse and bullous emphysema.

Key-words:
Bullous emphysema
smoked substance abuse
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Copyright © 2010. Sociedade Portuguesa de Pneumologia
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