array:24 [
  "pii" => "S2173511510700257"
  "issn" => "21735115"
  "doi" => "10.1016/S2173-5115(10)70025-7"
  "estado" => "S300"
  "fechaPublicacion" => "2010-01-01"
  "aid" => "70025"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2010"
  "documento" => "simple-article"
  "crossmark" => 0
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "cor"
  "cita" => "Rev Port Pneumol. 2010;16:157-61"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3916
    "formatos" => array:3 [
      "EPUB" => 233
      "HTML" => 2389
      "PDF" => 1294
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173511510700269"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(10)70026-9"
    "estado" => "S300"
    "fechaPublicacion" => "2010-01-01"
    "aid" => "70026"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "cor"
    "cita" => "Rev Port Pneumol. 2010;16:163-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3853
      "formatos" => array:3 [
        "EPUB" => 226
        "HTML" => 2243
        "PDF" => 1384
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Pneumomediastino espontâneo multiloculado em recém-nascido: Caso clínico"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "163"
          "paginaFinal" => "169"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Spontaneous multiloculated pneumomediastinum in a newborn: case report"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Dária Rezende, Inês V. Matos, M. João Oliveira, Conceição Costa, Luciana Reis, M Guilhermina Reis, Paula Ferreira, Salazar Abel"
          "autores" => array:8 [
            0 => array:2 [
              "nombre" => "Dária"
              "apellidos" => "Rezende"
            ]
            1 => array:2 [
              "nombre" => "Inês V."
              "apellidos" => "Matos"
            ]
            2 => array:2 [
              "nombre" => "M."
              "apellidos" => "João Oliveira"
            ]
            3 => array:2 [
              "nombre" => "Conceição"
              "apellidos" => "Costa"
            ]
            4 => array:2 [
              "nombre" => "Luciana"
              "apellidos" => "Reis"
            ]
            5 => array:2 [
              "nombre" => "M Guilhermina"
              "apellidos" => "Reis"
            ]
            6 => array:2 [
              "nombre" => "Paula"
              "apellidos" => "Ferreira"
            ]
            7 => array:2 [
              "nombre" => "Salazar"
              "apellidos" => "Abel"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511510700269?idApp=UINPBA00004E"
    "url" => "/21735115/0000001600000001/v1_201305151522/S2173511510700269/v1_201305151522/pt/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173511510700245"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(10)70024-5"
    "estado" => "S300"
    "fechaPublicacion" => "2010-01-01"
    "aid" => "70024"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "cor"
    "cita" => "Rev Port Pneumol. 2010;16:149-56"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3605
      "formatos" => array:3 [
        "EPUB" => 229
        "HTML" => 2096
        "PDF" => 1280
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Técnicas de dilatação broncoscópica e aplicação tópica de mitomicina C no tratamento da estenose traqueal pós-entubação – A propósito de dois casos clínicos"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "149"
          "paginaFinal" => "156"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Bronchoscopic dilation techniques and topical application of mitomycin-C in the treatment of tracheal stenosis post intubation – two case reports"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Susana Ferreira, Carla Nogueira, Ana Oliveira, Sofia Neves, José Almeida, João Moura e Sá, Parente Bárbara"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "Susana"
              "apellidos" => "Ferreira"
            ]
            1 => array:2 [
              "nombre" => "Carla"
              "apellidos" => "Nogueira"
            ]
            2 => array:2 [
              "nombre" => "Ana"
              "apellidos" => "Oliveira"
            ]
            3 => array:2 [
              "nombre" => "Sofia"
              "apellidos" => "Neves"
            ]
            4 => array:2 [
              "nombre" => "José"
              "apellidos" => "Almeida"
            ]
            5 => array:2 [
              "nombre" => "João"
              "apellidos" => "Moura e Sá"
            ]
            6 => array:2 [
              "nombre" => "Parente"
              "apellidos" => "Bárbara"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511510700245?idApp=UINPBA00004E"
    "url" => "/21735115/0000001600000001/v1_201305151522/S2173511510700245/v1_201305151522/pt/main.assets"
  ]
  "pt" => array:14 [
    "idiomaDefecto" => true
    "titulo" => "Enfisema bolhoso associado a consumo de drogas"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "157"
        "paginaFinal" => "161"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Sandra Figueiredo, Gabriela Fernandes, António Morais"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "Sandra"
            "apellidos" => "Figueiredo"
            "email" => array:1 [
              0 => "sandrabugalho@iol.pt"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">3</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Gabriela"
            "apellidos" => "Fernandes"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">2</span>"
                "identificador" => "aff0010"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">3</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Ant&#243;nio"
            "apellidos" => "Morais"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">2</span>"
                "identificador" => "aff0010"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">3</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Interna Complementar de Pneumologia&#47;<span class="elsevierStyleItalic">Resident&#44; Pulmonology</span>"
            "etiqueta" => "<span class="elsevierStyleSup">1</span>"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Assistente Hospitalar de Pneumologia&#47;<span class="elsevierStyleItalic">Consultant&#44; Pulmonology</span>"
            "etiqueta" => "<span class="elsevierStyleSup">2</span>"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Servi&#231;o de Pneumologia do Hospital de S&#227;o Jo&#227;o&#44; Porto"
            "etiqueta" => "<span class="elsevierStyleSup">3</span>"
            "identificador" => "aff0015"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Bullous emphysema associated with drug abuse"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2009-01-09"
    "fechaAceptado" => "2009-06-23"
    "PalabrasClave" => array:2 [
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec160618"
          "palabras" => array:2 [
            0 => "Enfisema bolhoso"
            1 => "drogas inaladas"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key-words"
          "identificador" => "xpalclavsec160619"
          "palabras" => array:2 [
            0 => "Bullous emphysema"
            1 => "smoked substance abuse"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "pt" => array:2 [
        "titulo" => "Resumo"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">O enfisema bolhoso &#233; caracterizado pelo aumento dos espa&#231;os a&#233;reos distais ao bronqu&#237;olo terminal com perda das paredes alveolares&#46; V&#225;rias etiologias t&#234;m sido descritas&#44; nomeadamente a defici&#234;ncia de alfa1-antitripsina e o consumo de tabaco&#46; &#192; excep&#231;&#227;o da defici&#234;ncia de alfa1-antitripsina&#44; alguns casos de enfisema bolhoso no jovem continuam sem etiologia conhecida&#46; T&#234;m sido descritos alguns casos associados a consumo de drogas&#46; O tabagismo associado ao consumo de drogas possivelmente criar&#225; as condi&#231;&#245;es para o desenvolvimento de bolhas&#44; com particular exuber&#226;ncia pelos lobos superiores&#46; Os autores descrevem dois casos cl&#237;nicos de doentes jovens&#44; com hist&#243;ria de consumo de drogas inaladas e enfisema bolhoso&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Bullous emphysema is characterized by permanent enlargement of airspaces distal to the terminal bronchiole accompanied by destruction of alveolar walls&#46; Several aetiologies have been described&#44; namely deficiency of &#945;<span class="elsevierStyleInf">1</span>-antitrypsin and the consumption of tobacco&#46; With the exception of the deficiency of &#945;<span class="elsevierStyleInf">1</span>-antitrypsin&#44; some cases of bullous emphysema in the young adult continue without known aetiology&#46; Some cases of bullous emphysema have been described&#44; emphasising the relationship between the disease and drug consumption&#46; The association possibly creates the conditions for the development of large lung bullae&#44; with particular exuberance for the superior lobes&#46; The authors describe two clinical cases of young patients&#44; with history of consumption of smoked subs tance abuse and bullous emphysema&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:10 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ectasy-associated pneumomediastinum"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46;F&#46; Marasco"
                            1 => "H&#46;K&#46; Lim"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1308/003588407X183373"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann R Coll Surg Engl"
                        "fecha" => "2007"
                        "volumen" => "89"
                        "paginaInicial" => "389"
                        "paginaFinal" => "393"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17535617"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Restrepo CS&#44; Carrilo J&#193;&#44; Martinez S&#44; <span class="elsevierStyleItalic">et al</span>&#46; Pulmonary Complications from coca&#237;ne and coca&#237;ne-based substances&#58; Imaging manifestations&#46; RadioGraphics 7&#40;4&#41;&#58;941&#8211;956&#46;"
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Emphysema and secondary pneumothorax in young adults smoking cannabis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46; Beshay"
                            1 => "H&#46; Kaiser"
                            2 => "D&#46; Niedhart"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ejcts.2007.07.039"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Cardiothorac Surg"
                        "fecha" => "2007"
                        "volumen" => "32"
                        "paginaInicial" => "834"
                        "paginaFinal" => "838"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17931876"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bullous pulmonary damage in users of intravenous drugs"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "D&#46;S&#46; Goldstein"
                            1 => "J&#46;P&#46; Karpel"
                            2 => "D&#46; Appel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1986"
                        "volumen" => "89"
                        "paginaInicial" => "266"
                        "paginaFinal" => "269"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3943387"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary complications of intravenous drug abuse&#58; experience at an innercity hospital"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;E&#46; O&#8217; Donnell"
                            1 => "L&#46;S&#46; Pappas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1988"
                        "volumen" => "94"
                        "paginaInicial" => "251"
                        "paginaFinal" => "253"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3396399"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary talc granulomas&#44; pulmonary fibrosis and pulmonary hipertension resulting from intravenous injection of talccontaining dugs intended for oral use"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;D&#46; William Clifford Roberts"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "BUMC Proceedings"
                        "fecha" => "2002"
                        "volumen" => "15"
                        "paginaInicial" => "260"
                        "paginaFinal" => "261"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16333448"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Talc granulomatosis and angiothrombotic pulmonary hypertension in drug addicts"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;P&#46; Genereux"
                            1 => "H&#46;E&#46; Emson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Can Assoc Radiol"
                        "fecha" => "1974"
                        "volumen" => "25"
                        "paginaInicial" => "187"
                        "paginaFinal" => "193"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary &#8216;mainline&#8217; granulomatosis&#58; talcosis of intrevenous methadone abuse"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "P&#46;J&#46;A&#46; Pare"
                            1 => "R&#46;G&#46; Fraser"
                            2 => "J&#46;C&#46; Hogg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Medicine"
                        "fecha" => "1979"
                        "volumen" => "58"
                        "paginaInicial" => "229"
                        "paginaFinal" => "239"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/449659"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Talc granulomatosis&#58; laboratory findings similar to sarcoidosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "H&#46;W&#46; Farber"
                            1 => "R&#46;P&#46; Fairman"
                            2 => "F&#46;L&#46; Glauser"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/arrd.1982.125.2.258"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1982"
                        "volumen" => "125"
                        "paginaInicial" => "258"
                        "paginaFinal" => "261"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6278999"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lung disease in reformed drug addicts&#58; diagnostic and physiologic correlations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "D&#46; Tomashow"
                            1 => "W&#46;B&#46; Summer"
                            2 => "J&#46; Soin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "John Hopkins Med J"
                        "fecha" => "1977"
                        "volumen" => "141"
                        "paginaInicial" => "1"
                        "paginaFinal" => "8"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "pt"
  "url" => "/21735115/0000001600000001/v1_201305151522/S2173511510700257/v1_201305151522/pt/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9550"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case Report&#47;Caso Cl&#237;nico"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001600000001/v1_201305151522/S2173511510700257/v1_201305151522/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511510700257?idApp=UINPBA00004E"
]
Share
Journal Information
Vol. 16. Issue 1.
Pages 157-161 (January - February 2010)
Share
Share
Download PDF
More article options
Vol. 16. Issue 1.
Pages 157-161 (January - February 2010)
Full text access
Enfisema bolhoso associado a consumo de drogas
Bullous emphysema associated with drug abuse
Visits
883
Sandra Figueiredo1,3, Gabriela Fernandes2,3, António Morais2,3
1 Interna Complementar de Pneumologia/Resident, Pulmonology
2 Assistente Hospitalar de Pneumologia/Consultant, Pulmonology
3 Serviço de Pneumologia do Hospital de São João, Porto
This item has received
Article information
Resumo

O enfisema bolhoso é caracterizado pelo aumento dos espaços aéreos distais ao bronquíolo terminal com perda das paredes alveolares. Várias etiologias têm sido descritas, nomeadamente a deficiência de alfa1-antitripsina e o consumo de tabaco. À excepção da deficiência de alfa1-antitripsina, alguns casos de enfisema bolhoso no jovem continuam sem etiologia conhecida. Têm sido descritos alguns casos associados a consumo de drogas. O tabagismo associado ao consumo de drogas possivelmente criará as condições para o desenvolvimento de bolhas, com particular exuberância pelos lobos superiores. Os autores descrevem dois casos clínicos de doentes jovens, com história de consumo de drogas inaladas e enfisema bolhoso.

Palavras-chave:
Enfisema bolhoso
drogas inaladas
Abstract

Bullous emphysema is characterized by permanent enlargement of airspaces distal to the terminal bronchiole accompanied by destruction of alveolar walls. Several aetiologies have been described, namely deficiency of α1-antitrypsin and the consumption of tobacco. With the exception of the deficiency of α1-antitrypsin, some cases of bullous emphysema in the young adult continue without known aetiology. Some cases of bullous emphysema have been described, emphasising the relationship between the disease and drug consumption. The association possibly creates the conditions for the development of large lung bullae, with particular exuberance for the superior lobes. The authors describe two clinical cases of young patients, with history of consumption of smoked subs tance abuse and bullous emphysema.

Key-words:
Bullous emphysema
smoked substance abuse
Full text is only aviable in PDF
Bibliografia
[1]
S.F. Marasco, H.K. Lim.
Ectasy-associated pneumomediastinum.
Ann R Coll Surg Engl, 89 (2007), pp. 389-393
[2]
Restrepo CS, Carrilo JÁ, Martinez S, et al. Pulmonary Complications from cocaíne and cocaíne-based substances: Imaging manifestations. RadioGraphics 7(4):941–956.
[3]
M. Beshay, H. Kaiser, D. Niedhart, et al.
Emphysema and secondary pneumothorax in young adults smoking cannabis.
Eur J Cardiothorac Surg, 32 (2007), pp. 834-838
[4]
D.S. Goldstein, J.P. Karpel, D. Appel, et al.
Bullous pulmonary damage in users of intravenous drugs.
Chest, 89 (1986), pp. 266-269
[5]
A.E. O’ Donnell, L.S. Pappas.
Pulmonary complications of intravenous drug abuse: experience at an innercity hospital.
Chest, 94 (1988), pp. 251-253
[6]
M.D. William Clifford Roberts.
Pulmonary talc granulomas, pulmonary fibrosis and pulmonary hipertension resulting from intravenous injection of talccontaining dugs intended for oral use.
BUMC Proceedings, 15 (2002), pp. 260-261
[7]
G.P. Genereux, H.E. Emson.
Talc granulomatosis and angiothrombotic pulmonary hypertension in drug addicts.
J Can Assoc Radiol, 25 (1974), pp. 187-193
[8]
P.J.A. Pare, R.G. Fraser, J.C. Hogg, et al.
Pulmonary ‘mainline’ granulomatosis: talcosis of intrevenous methadone abuse.
Medicine, 58 (1979), pp. 229-239
[9]
H.W. Farber, R.P. Fairman, F.L. Glauser.
Talc granulomatosis: laboratory findings similar to sarcoidosis.
Am Rev Respir Dis, 125 (1982), pp. 258-261
[10]
D. Tomashow, W.B. Summer, J. Soin, et al.
Lung disease in reformed drug addicts: diagnostic and physiologic correlations.
John Hopkins Med J, 141 (1977), pp. 1-8
Copyright © 2010. Sociedade Portuguesa de Pneumologia
Download PDF
Pulmonology
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?