array:24 [
  "pii" => "S0873215911000675"
  "issn" => "08732159"
  "doi" => "10.1016/j.rppneu.2011.06.003"
  "estado" => "S300"
  "fechaPublicacion" => "2012-01-01"
  "aid" => "31"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2011"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "sco"
  "cita" => "Rev Port Pneumol. 2012;18:39-41"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 9109
    "formatos" => array:3 [
      "EPUB" => 278
      "HTML" => 7547
      "PDF" => 1284
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S0873215911000699"
    "issn" => "08732159"
    "doi" => "10.1016/j.rppneu.2011.06.005"
    "estado" => "S300"
    "fechaPublicacion" => "2012-01-01"
    "aid" => "33"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "sco"
    "cita" => "Rev Port Pneumol. 2012;18:42-5"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 10259
      "formatos" => array:3 [
        "EPUB" => 294
        "HTML" => 8773
        "PDF" => 1192
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>"
      "titulo" => "Pulmonar collision tumor&#58; Metastatic adenoid cystic carcinoma and lung adenocarcinoma"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "42"
          "paginaFinal" => "45"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Tumor pulmonar de colis&#227;o&#58; met&#225;stase de carcinoma aden&#243;ide c&#237;stico e adenocarcinoma pulmonar"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 754
              "Ancho" => 944
              "Tamanyo" => 82542
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">CT image showing the nodule in the middle lobe&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "M&#46; Blanco, E&#46; Garc&#237;a-Font&#225;n, J&#46; R&#237;os, J&#46;E&#46; Rivo, R&#46; Fern&#225;ndez-Mart&#237;n, M&#46;A&#46; Ca&#241;izares"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Blanco"
            ]
            1 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Garc&#237;a-Font&#225;n"
            ]
            2 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "R&#237;os"
            ]
            3 => array:2 [
              "nombre" => "J&#46;E&#46;"
              "apellidos" => "Rivo"
            ]
            4 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Fern&#225;ndez-Mart&#237;n"
            ]
            5 => array:2 [
              "nombre" => "M&#46;A&#46;"
              "apellidos" => "Ca&#241;izares"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215911000699?idApp=UINPBA00004E"
    "url" => "/08732159/0000001800000001/v2_201509041308/S0873215911000699/v2_201509041308/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S0873215911000717"
    "issn" => "08732159"
    "doi" => "10.1016/j.rppneu.2011.05.007"
    "estado" => "S300"
    "fechaPublicacion" => "2012-01-01"
    "aid" => "35"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "sco"
    "cita" => "Rev Port Pneumol. 2012;18:34-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 12904
      "formatos" => array:3 [
        "EPUB" => 255
        "HTML" => 10286
        "PDF" => 2363
      ]
    ]
    "pt" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>"
      "titulo" => "Infe&#231;&#227;o por <span class="elsevierStyleItalic">staphylococcus aureus</span> meticilina-resistente da comunidade em Portugal"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => "pt"
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "34"
          "paginaFinal" => "38"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Community-associated methicillin-resistant <span class="elsevierStyleItalic">Staphylococcus aureus</span> infection in Portugal"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "pt" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "R&#46; Nazareth, J&#46; Gon&#231;alves-Pereira, A&#46; Tavares, M&#46; Miragaia, H&#46; de Lencastre, J&#46; Silvestre, P&#46; Freitas, E&#46; Gon&#231;alves, F&#46; Martins, V&#46; Mendes, C&#46; Tapadinhas, P&#46; P&#243;voa"
          "autores" => array:12 [
            0 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Nazareth"
            ]
            1 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Gon&#231;alves-Pereira"
            ]
            2 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Tavares"
            ]
            3 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Miragaia"
            ]
            4 => array:2 [
              "nombre" => "H&#46;"
              "apellidos" => "de Lencastre"
            ]
            5 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Silvestre"
            ]
            6 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "Freitas"
            ]
            7 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Gon&#231;alves"
            ]
            8 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Martins"
            ]
            9 => array:2 [
              "nombre" => "V&#46;"
              "apellidos" => "Mendes"
            ]
            10 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Tapadinhas"
            ]
            11 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "P&#243;voa"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215911000717?idApp=UINPBA00004E"
    "url" => "/08732159/0000001800000001/v2_201509041308/S0873215911000717/v2_201509041308/pt/main.assets"
  ]
  "en" => array:18 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>"
    "titulo" => "Well-differentiated fetal adenocarcinoma&#58; A very uncommon malignant lung tumor"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "39"
        "paginaFinal" => "41"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "H&#46; El Ouazzani, A&#46; Jniene, M&#46; Bouchikh, L&#46; Achachi, M&#46; El ftouh, A&#46; Achir, M&#46;T&#46; El fassy Fihry"
        "autores" => array:7 [
          0 => array:3 [
            "nombre" => "H&#46;"
            "apellidos" => "El Ouazzani"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          1 => array:4 [
            "nombre" => "A&#46;"
            "apellidos" => "Jniene"
            "email" => array:1 [
              0 => "asmaajniene&#64;gmail&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "Bouchikh"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "L&#46;"
            "apellidos" => "Achachi"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "El ftouh"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "A&#46;"
            "apellidos" => "Achir"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          6 => array:3 [
            "nombre" => "M&#46;T&#46;"
            "apellidos" => "El fassy Fihry"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Department of pulmonology&#44; Ibn Sina Hospital&#44; Rabat&#44; Morocco"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Department of Thoracic surgery&#44; Ibn Sina Hospital&#44; Rabat&#44; Morocco"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2&#44; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2v3.jpeg"
            "Alto" => 1508
            "Ancho" => 964
            "Tamanyo" => 149794
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A computed tomography scan showing an inhomogenous mass partially cystic&#44; budding at the lingular bronchi and then develops in intrathoracic without mediastinal lymphadenopathy or pleural effusion&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Fetal Adenocarcinoma is a very uncommon malignant tumor originating in the lung&#44; and was first described by Kradin et al&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> as a subtype of pulmonary blastoma&#44; which resembled the epithelial component of the fetal lung without sarcomatous contingent&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">In 1984&#44; the term fetal adenocarcinoma was introduced by Kodama et al&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> 14 years later Nakatani et al&#46; identified 2 groups&#58; well differentiated occurring in young women and with a good prognosis and poorly differentiated with a similar prognosis to classical non-small cell carcinoma&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Fetal adenocarcinoma has been considered in the WHO classification since 1999 as a solid adenocarcinoma with mucin production&#46; However&#44; a new international multidisciplinary classification&#44; which focused on lung adenocarcinoma to standardize terminology and improve treatment and predict prognosis&#44; does not consider fetal adenocarcinoma as a solid adenocarcinoma with mucin production but as a variant of invasive adenocarcinoma&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">We &#40;The authors&#41; report a case of a 38-year-old female patient with WDFA&#44; and discuss the unusual features of this type of tumor&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Case report</span><p id="par0020" class="elsevierStylePara elsevierViewall">A 38 year old woman presented with a one year history of dyspnea for which she was put on a short-acting bronchodilator with no further testing&#44; in particular no chest X-ray considering she was in the early stages of pregnancy&#46; Two months after delivery&#44; she reported an aggravation of her dyspnea with no other respiratory or extra respiratory signs and was examined two months later&#46; She had no significant past medical history&#59; she had no history of smoking&#46; The physical examination was normal&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">A chest X-ray &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41; showed a hilar and paracardial left opacity with a well defined border and internal margin which extended into the mediastimum&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">A computed tomography scan &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Figs&#46; 2 and 3</a>&#41; revealed a partially cystic heterogeneous mass&#44; forming at the lingular bronchi and then developing in intrathoracic without mediastinal lymphadenopathy or pleural effusion&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">Bronchoscopy confirmed a whitish lingular lesion at the orifice&#44; with total occlusion of the airway lumen&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Microscopic examination of an endobronchial biopsy &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Figs&#46; 4 and 5</a>&#41; showed an obviously malignant tumor process which was extensively ulcerated on the surface&#46; It was made up of malignant glandular cells growing in tubules and papillary structures&#44; sometimes reproducing endometrioid differentiation&#46; These malignant cells had prominent clear cytoplasm&#44; and squamoid morules were present&#46; Some of the lumen of the glands were empty&#44; others contained eosinophilic material&#46; The dividing stroma was fibrous&#46; Large areas of necrosis were observed&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0045" class="elsevierStylePara elsevierViewall">The patient was assessed clinically at stage T3N0M0&#46; Thoracotomy was performed and the patient underwent a superior left lobectomy with lymphadenectomy&#46; The tumor measured 6<span class="elsevierStyleHsp" style=""></span>cm at the widest diameter&#46; Microscopic examination confirmed the description above&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Discussion</span><p id="par0050" class="elsevierStylePara elsevierViewall">Lung tumors resembling the fetal lung are a very uncommon primitive malignant tumor originating in the lung&#46; They include pulmonary blastoma and fetal adenocarcinoma&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> The incidence of this malignant tumor has been estimated at 0&#46;5&#37; of all primary lung tumors&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">In the series of Kodama et al&#46;&#44; all the patients were elderly males&#46; The majority died of their tumor&#46; Koss et al&#46; reported a series with better survival where almost all the patients were female&#46; In 1990&#44; Natakatani et al&#46; identified subcategories of fetal type adenocarcinoma where the prognosis was good&#44; specifically occurring among woman&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">In 1998 Natakatani et al&#46; identified 2 groups of fetal adenocarcinoma&#58; WDFA occurring in young women&#44; generally non smokers&#44; which had a good prognosis&#44; also called endodermal tumor resembling the fetal lung&#44; and poorly differentiated fetal adenocarcinoma with a similar prognosis to classical non-small cell carcinoma&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Histologically&#44; the WDFA element characteristically demonstrates glandular elements with tubules composed of glycogen-rich&#44; non-ciliated cells that resemble fetal lung tubules and squamoid morules may be seen with clear nuclei within lumens&#46; The immature mesenchyme and epithelium mimic the embryonic lung at 10&#8211;16 weeks gestation&#46; The name WDFA is therefore derived from the histological appearances of the tumor&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">6&#44;7</span></a> Most are low grade with a favorable outcome&#46; When mixtures occur with other histological subtypes&#44; the tumor should be classified according to the predominant component&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">A correct pre-operative diagnosis of endobronchial biopsies is difficult&#46; Although a correct diagnosis may be achieved after resection&#44; thorough sampling is essential&#44; because the tumor may be heterogenic&#44; with components characteristic of WDFA and pulmonary blastoma<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> or components of more conventional adenocarcinoma&#46; In both cases the prognosis is worse&#46; Indeed&#44; the 10-year survival for WDFA is about 75&#37; versus about 15&#37; for pulmonary blastoma&#46; In our case the presence of this latter was excluded by conventional microscopy&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">The standard treatment is surgical resection&#44; if technically possible&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Conclusion</span><p id="par0080" class="elsevierStylePara elsevierViewall">This case of well-differentiated fetal adenocarcinoma illustrates the importance of establishing an accurate diagnosis when a pregnant woman presents with respiratory symptoms by carrying out the necessary tests&#44; obviously taking great care&#44; especially when the symptomatic treatment does not provide any improvement&#46; However&#44; report emphasizes how important it is for clinicians to consider and identify this rare variant of adenocarcinoma because of its low grade malignancy associated with good prognosis&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:9 [
        0 => array:2 [
          "identificador" => "xres547625"
          "titulo" => "Abstract"
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec565504"
          "titulo" => "Keywords"
        ]
        2 => array:2 [
          "identificador" => "xres547624"
          "titulo" => "Resumo"
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec565505"
          "titulo" => "Palavras-chave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Case report"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Discussion"
        ]
        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Conclusion"
        ]
        8 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2011-01-19"
    "fechaAceptado" => "2011-06-06"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec565504"
          "palabras" => array:3 [
            0 => "Well-differentiated fetal adenocarcinoma"
            1 => "Lung"
            2 => "Good prognosis"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec565505"
          "palabras" => array:3 [
            0 => "Adenocarcinoma fetal bem diferenciado"
            1 => "pulm&#227;o"
            2 => "bom progn&#243;stico"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Well-differentiated fetal adenocarcinoma &#40;WDFA&#41; is a very uncommon malignant tumor originating in the lung&#46; This report describes the case of a 38-year-old woman with a WDFA treated by surgery&#46; The malignancy is low grade and associated with a good prognosis&#44; and so it is important for clinicians to be aware of and to identify this rare variant of adenocarcinoma&#46;</p></span>"
      ]
      "es" => array:2 [
        "titulo" => "Resumo"
        "resumen" => "<span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">O adenocarcinoma fetal bem diferenciado &#40;WDFA&#44; de acordo com a sigla em ingl&#234;s&#41; &#233; um tumor maligno no pulm&#227;o muito invulgar que tem origem no pulm&#227;o&#46; Este relat&#243;rio descreve o caso de uma mulher de 38 anos com WDFA tratada atrav&#233;s de cirurgia&#46; A malignidade &#233; de baixo grau e est&#225; associada a um bom progn&#243;stico e&#44; por isso&#44; &#233; importante que os cl&#237;nicos estejam atentos e identifiquem esta variante rara de adenocarcinoma&#46;</p></span>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 752
            "Ancho" => 900
            "Tamanyo" => 53387
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Chest X-ray demonstrating a hilar and paracardial left opacity&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2&#44; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2v3.jpeg"
            "Alto" => 1508
            "Ancho" => 964
            "Tamanyo" => 149794
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A computed tomography scan showing an inhomogenous mass partially cystic&#44; budding at the lingular bronchi and then develops in intrathoracic without mediastinal lymphadenopathy or pleural effusion&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 4&#44; 5"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr4v5.jpeg"
            "Alto" => 615
            "Ancho" => 1600
            "Tamanyo" => 278276
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Microscopic examination of an endobronchial biopsy showing malignant glandular cells growing in tubules and papillary structures&#44; reproducing sometimes endometrioid differentiation&#46; These malignant cells have prominent clear cytoplasm&#44; and squamoid morules were present&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:8 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary blastoma with argyrophill cells and lacking sarcomatous features &#40;pulmonary endodermal tumor resembling fetal lung&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46;L&#46; Kradin"
                            1 => "S&#46;E&#46; Kirkham"
                            2 => "E&#46;J&#46; Young"
                            3 => "G&#46;R&#46; Dickersin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1982"
                        "volumen" => "6"
                        "paginaInicial" => "165"
                        "paginaFinal" => "172"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6179430"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Six cases of well differentiated adenocarcinoma stimulating fetal lung tubules in pseudoglandular stage"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "T&#46; Kodoma"
                            1 => "T&#46; Koide"
                            2 => "Y&#46; Shimosato"
                            3 => "T&#46; Naruke"
                            4 => "S&#46; Watanabe"
                            5 => "J&#46; Shimase"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1984"
                        "volumen" => "8"
                        "paginaInicial" => "734"
                        "paginaFinal" => "744"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary adenocarcinomas of fetal lung type&#58; a clinicopathologic study indicating differences in histology epidemiology and natural history of low-grade and high grade forms"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "Y&#46; Nakatani"
                            1 => "H&#46; Kitamura"
                            2 => "Y&#46; Inayama"
                            3 => "S&#46; Kamijo"
                            4 => "Y&#46; Nagashima"
                            5 => "K&#46; Shimoyama"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1998"
                        "volumen" => "22"
                        "paginaInicial" => "399"
                        "paginaFinal" => "411"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9537466"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "International Association for the Study of Lung Cancer&#47;American Thoracic Society&#47;European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "W&#46;D&#46; Travis"
                            1 => "E&#46; Brambilla"
                            2 => "M&#46; Noguchi"
                            3 => "A&#46;G&#46; Nicholson"
                            4 => "K&#46;R&#46; Geisinger"
                            5 => "Y&#46; Yatabe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Thoric Oncol"
                        "fecha" => "2011"
                        "volumen" => "6"
                        "paginaInicial" => "244"
                        "paginaFinal" => "285"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ad&#233;nocarcinome pulmonaire bien diff&#233;renci&#233; de type f&#339;tal&#58; une tumeur de bon pronostic"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "L&#46; Amirat"
                            1 => "F&#46; le Pimpec Barthes"
                            2 => "C&#46; Danel"
                            3 => "B&#46; Poulet"
                            4 => "M&#46; Riquet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Mal Respir"
                        "fecha" => "2003"
                        "volumen" => "20"
                        "paginaInicial" => "429"
                        "paginaFinal" => "432"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12910118"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Well differentiated fetal adenocarcinoma of the lung in a 29-year-old woman"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "K&#46;M&#46; Sheehan"
                            1 => "J&#46; Curran"
                            2 => "E&#46;W&#46; Kay"
                            3 => "P&#46; Broe"
                            4 => "A&#46; Grace"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Pathol"
                        "fecha" => "2003"
                        "volumen" => "56"
                        "paginaInicial" => "478"
                        "paginaFinal" => "479"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12783979"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A 49-year-old woman with well-differentiated fetal adenocarcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;J&#46; Politiek"
                            1 => "B&#46; Vrugt"
                            2 => "R&#46; Aalbers"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "The Netherlands J Med"
                        "fecha" => "2001"
                        "volumen" => "58"
                        "paginaInicial" => "177"
                        "paginaFinal" => "180"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Haemoptysis in pregnancy caused by a well-differentiated fetal adenocarcinoma&#58; a case report"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "R&#46;J&#46; Thompson"
                            1 => "P&#46;S&#46; Hasleton"
                            2 => "P&#46;M&#46; Taylor"
                            3 => "M&#46; Woodhead"
                            4 => "L&#46;M&#46; Byrd"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/1752-1947-4-17"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Med Case Rep"
                        "fecha" => "2010"
                        "volumen" => "4"
                        "paginaInicial" => "17"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20205788"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/08732159/0000001800000001/v2_201509041308/S0873215911000675/v2_201509041308/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9580"
    "tipo" => "SECCION"
    "pt" => array:2 [
      "titulo" => "Casos cl&#237;nicos"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "pt"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/08732159/0000001800000001/v2_201509041308/S0873215911000675/v2_201509041308/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215911000675?idApp=UINPBA00004E"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Case report
Well-differentiated fetal adenocarcinoma: A very uncommon malignant lung tumor
H. El Ouazzania, A. Jnienea,
Corresponding author
asmaajniene@gmail.com

Corresponding author.
, M. Bouchikhb, L. Achachia, M. El ftouha, A. Achirb, M.T. El fassy Fihrya
a Department of pulmonology, Ibn Sina Hospital, Rabat, Morocco
b Department of Thoracic surgery, Ibn Sina Hospital, Rabat, Morocco
Read
14012
Times
was read the article
2875
Total PDF
11137
Total HTML
Share statistics
 array:24 [
  "pii" => "S0873215911000675"
  "issn" => "08732159"
  "doi" => "10.1016/j.rppneu.2011.06.003"
  "estado" => "S300"
  "fechaPublicacion" => "2012-01-01"
  "aid" => "31"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2011"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "sco"
  "cita" => "Rev Port Pneumol. 2012;18:39-41"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 9109
    "formatos" => array:3 [
      "EPUB" => 278
      "HTML" => 7547
      "PDF" => 1284
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S0873215911000699"
    "issn" => "08732159"
    "doi" => "10.1016/j.rppneu.2011.06.005"
    "estado" => "S300"
    "fechaPublicacion" => "2012-01-01"
    "aid" => "33"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "sco"
    "cita" => "Rev Port Pneumol. 2012;18:42-5"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 10259
      "formatos" => array:3 [
        "EPUB" => 294
        "HTML" => 8773
        "PDF" => 1192
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>"
      "titulo" => "Pulmonar collision tumor&#58; Metastatic adenoid cystic carcinoma and lung adenocarcinoma"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "42"
          "paginaFinal" => "45"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Tumor pulmonar de colis&#227;o&#58; met&#225;stase de carcinoma aden&#243;ide c&#237;stico e adenocarcinoma pulmonar"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 754
              "Ancho" => 944
              "Tamanyo" => 82542
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">CT image showing the nodule in the middle lobe&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "M&#46; Blanco, E&#46; Garc&#237;a-Font&#225;n, J&#46; R&#237;os, J&#46;E&#46; Rivo, R&#46; Fern&#225;ndez-Mart&#237;n, M&#46;A&#46; Ca&#241;izares"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Blanco"
            ]
            1 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Garc&#237;a-Font&#225;n"
            ]
            2 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "R&#237;os"
            ]
            3 => array:2 [
              "nombre" => "J&#46;E&#46;"
              "apellidos" => "Rivo"
            ]
            4 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Fern&#225;ndez-Mart&#237;n"
            ]
            5 => array:2 [
              "nombre" => "M&#46;A&#46;"
              "apellidos" => "Ca&#241;izares"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215911000699?idApp=UINPBA00004E"
    "url" => "/08732159/0000001800000001/v2_201509041308/S0873215911000699/v2_201509041308/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S0873215911000717"
    "issn" => "08732159"
    "doi" => "10.1016/j.rppneu.2011.05.007"
    "estado" => "S300"
    "fechaPublicacion" => "2012-01-01"
    "aid" => "35"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "sco"
    "cita" => "Rev Port Pneumol. 2012;18:34-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 12904
      "formatos" => array:3 [
        "EPUB" => 255
        "HTML" => 10286
        "PDF" => 2363
      ]
    ]
    "pt" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>"
      "titulo" => "Infe&#231;&#227;o por <span class="elsevierStyleItalic">staphylococcus aureus</span> meticilina-resistente da comunidade em Portugal"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => "pt"
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "34"
          "paginaFinal" => "38"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Community-associated methicillin-resistant <span class="elsevierStyleItalic">Staphylococcus aureus</span> infection in Portugal"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "pt" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "R&#46; Nazareth, J&#46; Gon&#231;alves-Pereira, A&#46; Tavares, M&#46; Miragaia, H&#46; de Lencastre, J&#46; Silvestre, P&#46; Freitas, E&#46; Gon&#231;alves, F&#46; Martins, V&#46; Mendes, C&#46; Tapadinhas, P&#46; P&#243;voa"
          "autores" => array:12 [
            0 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Nazareth"
            ]
            1 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Gon&#231;alves-Pereira"
            ]
            2 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Tavares"
            ]
            3 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Miragaia"
            ]
            4 => array:2 [
              "nombre" => "H&#46;"
              "apellidos" => "de Lencastre"
            ]
            5 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Silvestre"
            ]
            6 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "Freitas"
            ]
            7 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Gon&#231;alves"
            ]
            8 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Martins"
            ]
            9 => array:2 [
              "nombre" => "V&#46;"
              "apellidos" => "Mendes"
            ]
            10 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Tapadinhas"
            ]
            11 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "P&#243;voa"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215911000717?idApp=UINPBA00004E"
    "url" => "/08732159/0000001800000001/v2_201509041308/S0873215911000717/v2_201509041308/pt/main.assets"
  ]
  "en" => array:18 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>"
    "titulo" => "Well-differentiated fetal adenocarcinoma&#58; A very uncommon malignant lung tumor"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "39"
        "paginaFinal" => "41"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "H&#46; El Ouazzani, A&#46; Jniene, M&#46; Bouchikh, L&#46; Achachi, M&#46; El ftouh, A&#46; Achir, M&#46;T&#46; El fassy Fihry"
        "autores" => array:7 [
          0 => array:3 [
            "nombre" => "H&#46;"
            "apellidos" => "El Ouazzani"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          1 => array:4 [
            "nombre" => "A&#46;"
            "apellidos" => "Jniene"
            "email" => array:1 [
              0 => "asmaajniene&#64;gmail&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "Bouchikh"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "L&#46;"
            "apellidos" => "Achachi"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "El ftouh"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "A&#46;"
            "apellidos" => "Achir"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          6 => array:3 [
            "nombre" => "M&#46;T&#46;"
            "apellidos" => "El fassy Fihry"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Department of pulmonology&#44; Ibn Sina Hospital&#44; Rabat&#44; Morocco"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Department of Thoracic surgery&#44; Ibn Sina Hospital&#44; Rabat&#44; Morocco"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2&#44; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2v3.jpeg"
            "Alto" => 1508
            "Ancho" => 964
            "Tamanyo" => 149794
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A computed tomography scan showing an inhomogenous mass partially cystic&#44; budding at the lingular bronchi and then develops in intrathoracic without mediastinal lymphadenopathy or pleural effusion&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Fetal Adenocarcinoma is a very uncommon malignant tumor originating in the lung&#44; and was first described by Kradin et al&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> as a subtype of pulmonary blastoma&#44; which resembled the epithelial component of the fetal lung without sarcomatous contingent&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">In 1984&#44; the term fetal adenocarcinoma was introduced by Kodama et al&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> 14 years later Nakatani et al&#46; identified 2 groups&#58; well differentiated occurring in young women and with a good prognosis and poorly differentiated with a similar prognosis to classical non-small cell carcinoma&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Fetal adenocarcinoma has been considered in the WHO classification since 1999 as a solid adenocarcinoma with mucin production&#46; However&#44; a new international multidisciplinary classification&#44; which focused on lung adenocarcinoma to standardize terminology and improve treatment and predict prognosis&#44; does not consider fetal adenocarcinoma as a solid adenocarcinoma with mucin production but as a variant of invasive adenocarcinoma&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">We &#40;The authors&#41; report a case of a 38-year-old female patient with WDFA&#44; and discuss the unusual features of this type of tumor&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Case report</span><p id="par0020" class="elsevierStylePara elsevierViewall">A 38 year old woman presented with a one year history of dyspnea for which she was put on a short-acting bronchodilator with no further testing&#44; in particular no chest X-ray considering she was in the early stages of pregnancy&#46; Two months after delivery&#44; she reported an aggravation of her dyspnea with no other respiratory or extra respiratory signs and was examined two months later&#46; She had no significant past medical history&#59; she had no history of smoking&#46; The physical examination was normal&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">A chest X-ray &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41; showed a hilar and paracardial left opacity with a well defined border and internal margin which extended into the mediastimum&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">A computed tomography scan &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Figs&#46; 2 and 3</a>&#41; revealed a partially cystic heterogeneous mass&#44; forming at the lingular bronchi and then developing in intrathoracic without mediastinal lymphadenopathy or pleural effusion&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">Bronchoscopy confirmed a whitish lingular lesion at the orifice&#44; with total occlusion of the airway lumen&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Microscopic examination of an endobronchial biopsy &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Figs&#46; 4 and 5</a>&#41; showed an obviously malignant tumor process which was extensively ulcerated on the surface&#46; It was made up of malignant glandular cells growing in tubules and papillary structures&#44; sometimes reproducing endometrioid differentiation&#46; These malignant cells had prominent clear cytoplasm&#44; and squamoid morules were present&#46; Some of the lumen of the glands were empty&#44; others contained eosinophilic material&#46; The dividing stroma was fibrous&#46; Large areas of necrosis were observed&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0045" class="elsevierStylePara elsevierViewall">The patient was assessed clinically at stage T3N0M0&#46; Thoracotomy was performed and the patient underwent a superior left lobectomy with lymphadenectomy&#46; The tumor measured 6<span class="elsevierStyleHsp" style=""></span>cm at the widest diameter&#46; Microscopic examination confirmed the description above&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Discussion</span><p id="par0050" class="elsevierStylePara elsevierViewall">Lung tumors resembling the fetal lung are a very uncommon primitive malignant tumor originating in the lung&#46; They include pulmonary blastoma and fetal adenocarcinoma&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> The incidence of this malignant tumor has been estimated at 0&#46;5&#37; of all primary lung tumors&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">In the series of Kodama et al&#46;&#44; all the patients were elderly males&#46; The majority died of their tumor&#46; Koss et al&#46; reported a series with better survival where almost all the patients were female&#46; In 1990&#44; Natakatani et al&#46; identified subcategories of fetal type adenocarcinoma where the prognosis was good&#44; specifically occurring among woman&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">In 1998 Natakatani et al&#46; identified 2 groups of fetal adenocarcinoma&#58; WDFA occurring in young women&#44; generally non smokers&#44; which had a good prognosis&#44; also called endodermal tumor resembling the fetal lung&#44; and poorly differentiated fetal adenocarcinoma with a similar prognosis to classical non-small cell carcinoma&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Histologically&#44; the WDFA element characteristically demonstrates glandular elements with tubules composed of glycogen-rich&#44; non-ciliated cells that resemble fetal lung tubules and squamoid morules may be seen with clear nuclei within lumens&#46; The immature mesenchyme and epithelium mimic the embryonic lung at 10&#8211;16 weeks gestation&#46; The name WDFA is therefore derived from the histological appearances of the tumor&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">6&#44;7</span></a> Most are low grade with a favorable outcome&#46; When mixtures occur with other histological subtypes&#44; the tumor should be classified according to the predominant component&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">A correct pre-operative diagnosis of endobronchial biopsies is difficult&#46; Although a correct diagnosis may be achieved after resection&#44; thorough sampling is essential&#44; because the tumor may be heterogenic&#44; with components characteristic of WDFA and pulmonary blastoma<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> or components of more conventional adenocarcinoma&#46; In both cases the prognosis is worse&#46; Indeed&#44; the 10-year survival for WDFA is about 75&#37; versus about 15&#37; for pulmonary blastoma&#46; In our case the presence of this latter was excluded by conventional microscopy&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">The standard treatment is surgical resection&#44; if technically possible&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Conclusion</span><p id="par0080" class="elsevierStylePara elsevierViewall">This case of well-differentiated fetal adenocarcinoma illustrates the importance of establishing an accurate diagnosis when a pregnant woman presents with respiratory symptoms by carrying out the necessary tests&#44; obviously taking great care&#44; especially when the symptomatic treatment does not provide any improvement&#46; However&#44; report emphasizes how important it is for clinicians to consider and identify this rare variant of adenocarcinoma because of its low grade malignancy associated with good prognosis&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:9 [
        0 => array:2 [
          "identificador" => "xres547625"
          "titulo" => "Abstract"
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec565504"
          "titulo" => "Keywords"
        ]
        2 => array:2 [
          "identificador" => "xres547624"
          "titulo" => "Resumo"
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec565505"
          "titulo" => "Palavras-chave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Case report"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Discussion"
        ]
        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Conclusion"
        ]
        8 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2011-01-19"
    "fechaAceptado" => "2011-06-06"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec565504"
          "palabras" => array:3 [
            0 => "Well-differentiated fetal adenocarcinoma"
            1 => "Lung"
            2 => "Good prognosis"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec565505"
          "palabras" => array:3 [
            0 => "Adenocarcinoma fetal bem diferenciado"
            1 => "pulm&#227;o"
            2 => "bom progn&#243;stico"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Well-differentiated fetal adenocarcinoma &#40;WDFA&#41; is a very uncommon malignant tumor originating in the lung&#46; This report describes the case of a 38-year-old woman with a WDFA treated by surgery&#46; The malignancy is low grade and associated with a good prognosis&#44; and so it is important for clinicians to be aware of and to identify this rare variant of adenocarcinoma&#46;</p></span>"
      ]
      "es" => array:2 [
        "titulo" => "Resumo"
        "resumen" => "<span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">O adenocarcinoma fetal bem diferenciado &#40;WDFA&#44; de acordo com a sigla em ingl&#234;s&#41; &#233; um tumor maligno no pulm&#227;o muito invulgar que tem origem no pulm&#227;o&#46; Este relat&#243;rio descreve o caso de uma mulher de 38 anos com WDFA tratada atrav&#233;s de cirurgia&#46; A malignidade &#233; de baixo grau e est&#225; associada a um bom progn&#243;stico e&#44; por isso&#44; &#233; importante que os cl&#237;nicos estejam atentos e identifiquem esta variante rara de adenocarcinoma&#46;</p></span>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 752
            "Ancho" => 900
            "Tamanyo" => 53387
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Chest X-ray demonstrating a hilar and paracardial left opacity&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2&#44; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2v3.jpeg"
            "Alto" => 1508
            "Ancho" => 964
            "Tamanyo" => 149794
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A computed tomography scan showing an inhomogenous mass partially cystic&#44; budding at the lingular bronchi and then develops in intrathoracic without mediastinal lymphadenopathy or pleural effusion&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 4&#44; 5"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr4v5.jpeg"
            "Alto" => 615
            "Ancho" => 1600
            "Tamanyo" => 278276
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Microscopic examination of an endobronchial biopsy showing malignant glandular cells growing in tubules and papillary structures&#44; reproducing sometimes endometrioid differentiation&#46; These malignant cells have prominent clear cytoplasm&#44; and squamoid morules were present&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:8 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary blastoma with argyrophill cells and lacking sarcomatous features &#40;pulmonary endodermal tumor resembling fetal lung&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46;L&#46; Kradin"
                            1 => "S&#46;E&#46; Kirkham"
                            2 => "E&#46;J&#46; Young"
                            3 => "G&#46;R&#46; Dickersin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1982"
                        "volumen" => "6"
                        "paginaInicial" => "165"
                        "paginaFinal" => "172"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6179430"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Six cases of well differentiated adenocarcinoma stimulating fetal lung tubules in pseudoglandular stage"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "T&#46; Kodoma"
                            1 => "T&#46; Koide"
                            2 => "Y&#46; Shimosato"
                            3 => "T&#46; Naruke"
                            4 => "S&#46; Watanabe"
                            5 => "J&#46; Shimase"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1984"
                        "volumen" => "8"
                        "paginaInicial" => "734"
                        "paginaFinal" => "744"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary adenocarcinomas of fetal lung type&#58; a clinicopathologic study indicating differences in histology epidemiology and natural history of low-grade and high grade forms"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "Y&#46; Nakatani"
                            1 => "H&#46; Kitamura"
                            2 => "Y&#46; Inayama"
                            3 => "S&#46; Kamijo"
                            4 => "Y&#46; Nagashima"
                            5 => "K&#46; Shimoyama"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1998"
                        "volumen" => "22"
                        "paginaInicial" => "399"
                        "paginaFinal" => "411"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9537466"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "International Association for the Study of Lung Cancer&#47;American Thoracic Society&#47;European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "W&#46;D&#46; Travis"
                            1 => "E&#46; Brambilla"
                            2 => "M&#46; Noguchi"
                            3 => "A&#46;G&#46; Nicholson"
                            4 => "K&#46;R&#46; Geisinger"
                            5 => "Y&#46; Yatabe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Thoric Oncol"
                        "fecha" => "2011"
                        "volumen" => "6"
                        "paginaInicial" => "244"
                        "paginaFinal" => "285"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ad&#233;nocarcinome pulmonaire bien diff&#233;renci&#233; de type f&#339;tal&#58; une tumeur de bon pronostic"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "L&#46; Amirat"
                            1 => "F&#46; le Pimpec Barthes"
                            2 => "C&#46; Danel"
                            3 => "B&#46; Poulet"
                            4 => "M&#46; Riquet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Mal Respir"
                        "fecha" => "2003"
                        "volumen" => "20"
                        "paginaInicial" => "429"
                        "paginaFinal" => "432"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12910118"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Well differentiated fetal adenocarcinoma of the lung in a 29-year-old woman"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "K&#46;M&#46; Sheehan"
                            1 => "J&#46; Curran"
                            2 => "E&#46;W&#46; Kay"
                            3 => "P&#46; Broe"
                            4 => "A&#46; Grace"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Pathol"
                        "fecha" => "2003"
                        "volumen" => "56"
                        "paginaInicial" => "478"
                        "paginaFinal" => "479"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12783979"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A 49-year-old woman with well-differentiated fetal adenocarcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;J&#46; Politiek"
                            1 => "B&#46; Vrugt"
                            2 => "R&#46; Aalbers"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "The Netherlands J Med"
                        "fecha" => "2001"
                        "volumen" => "58"
                        "paginaInicial" => "177"
                        "paginaFinal" => "180"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Haemoptysis in pregnancy caused by a well-differentiated fetal adenocarcinoma&#58; a case report"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "R&#46;J&#46; Thompson"
                            1 => "P&#46;S&#46; Hasleton"
                            2 => "P&#46;M&#46; Taylor"
                            3 => "M&#46; Woodhead"
                            4 => "L&#46;M&#46; Byrd"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/1752-1947-4-17"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Med Case Rep"
                        "fecha" => "2010"
                        "volumen" => "4"
                        "paginaInicial" => "17"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20205788"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/08732159/0000001800000001/v2_201509041308/S0873215911000675/v2_201509041308/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9580"
    "tipo" => "SECCION"
    "pt" => array:2 [
      "titulo" => "Casos cl&#237;nicos"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "pt"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/08732159/0000001800000001/v2_201509041308/S0873215911000675/v2_201509041308/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215911000675?idApp=UINPBA00004E"
]
Article information
ISSN: 08732159
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 11 9 20
2024 October 66 35 101
2024 September 70 22 92
2024 August 93 34 127
2024 July 74 33 107
2024 June 58 36 94
2024 May 66 38 104
2024 April 64 36 100
2024 March 57 24 81
2024 February 77 28 105
2024 January 44 30 74
2023 December 35 21 56
2023 November 48 28 76
2023 October 54 35 89
2023 September 54 30 84
2023 August 42 26 68
2023 July 45 29 74
2023 June 48 14 62
2023 May 57 26 83
2023 April 48 15 63
2023 March 88 26 114
2023 February 54 18 72
2023 January 55 17 72
2022 December 72 19 91
2022 November 65 36 101
2022 October 56 29 85
2022 September 44 29 73
2022 August 57 39 96
2022 July 51 46 97
2022 June 42 30 72
2022 May 56 39 95
2022 April 57 33 90
2022 March 55 53 108
2022 February 56 35 91
2022 January 39 27 66
2021 December 33 37 70
2021 November 45 36 81
2021 October 38 46 84
2021 September 47 36 83
2021 August 45 20 65
2021 July 35 24 59
2021 June 33 21 54
2021 May 62 24 86
2021 April 149 41 190
2021 March 83 23 106
2021 February 66 22 88
2021 January 53 22 75
2020 December 56 15 71
2020 November 62 31 93
2020 October 57 15 72
2020 September 79 29 108
2020 August 107 30 137
2020 July 140 27 167
2020 June 133 21 154
2020 May 108 16 124
2020 April 88 9 97
2020 March 81 18 99
2020 February 88 15 103
2020 January 84 18 102
2019 December 82 19 101
2019 November 74 17 91
2019 October 88 19 107
2019 September 103 22 125
2019 August 159 21 180
2019 July 189 16 205
2019 June 164 11 175
2019 May 183 17 200
2019 April 181 35 216
2019 March 254 12 266
2019 February 224 7 231
2019 January 222 25 247
2018 December 129 5 134
2018 November 36 0 36
2018 October 31 12 43
2018 September 45 6 51
2018 August 53 28 81
2018 July 53 21 74
2018 June 75 17 92
2018 May 66 16 82
2018 April 112 19 131
2018 March 104 21 125
2018 February 47 10 57
2018 January 76 17 93
2017 December 89 12 101
2017 November 54 22 76
2017 October 32 19 51
2017 September 46 12 58
2017 August 51 21 72
2017 July 54 12 66
2017 June 60 30 90
2017 May 55 21 76
2017 April 43 3 46
2017 March 41 5 46
2017 February 22 5 27
2017 January 36 3 39
2016 December 34 12 46
2016 November 35 9 44
2016 October 44 8 52
2016 September 111 5 116
2016 August 26 3 29
2016 July 11 6 17
2016 June 0 4 4
2016 May 0 6 6
2016 April 49 2 51
2016 March 74 16 90
2016 February 94 18 112
2016 January 77 7 84
2015 December 76 7 83
2015 November 54 12 66
2015 October 71 10 81
2015 September 74 13 87
2015 August 57 14 71
2015 July 80 8 88
2015 June 54 5 59
2015 May 66 12 78
2015 April 93 12 105
2015 March 84 8 92
2015 February 60 4 64
2015 January 70 13 83
2014 December 100 9 109
2014 November 73 9 82
2014 October 96 12 108
2014 September 89 16 105
2014 August 88 11 99
2014 July 85 9 94
2014 June 78 8 86
2014 May 93 8 101
2014 April 95 13 108
2014 March 111 15 126
2014 February 143 11 154
2014 January 141 20 161
2013 December 93 11 104
2013 November 93 16 109
2013 October 76 13 89
2013 September 67 18 85
2013 August 79 20 99
2013 July 79 22 101
2013 June 64 15 79
2013 May 73 19 92
2013 April 77 24 101
2013 March 79 15 94
2013 February 62 26 88
2013 January 78 26 104
2012 December 61 17 78
2012 November 70 24 94
2012 October 52 68 120
2012 September 24 7 31
2012 January 361 0 361
Show all

Follow this link to access the full text of the article

Pulmonology

Are you a health professional able to prescribe or dispense drugs?