array:24 [
  "pii" => "S0873215913000858"
  "issn" => "08732159"
  "doi" => "10.1016/j.rppneu.2013.07.001"
  "estado" => "S300"
  "fechaPublicacion" => "2013-09-01"
  "aid" => "170"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2013"
  "documento" => "simple-article"
  "crossmark" => 0
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "edi"
  "cita" => "Rev Port Pneumol. 2013;19:190-1"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 4670
    "formatos" => array:3 [
      "EPUB" => 276
      "HTML" => 3257
      "PDF" => 1137
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S0873215913000585"
    "issn" => "08732159"
    "doi" => "10.1016/j.rppneu.2012.10.006"
    "estado" => "S300"
    "fechaPublicacion" => "2013-09-01"
    "aid" => "160"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Pneumol. 2013;19:192-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 8864
      "formatos" => array:3 [
        "EPUB" => 282
        "HTML" => 6415
        "PDF" => 2167
      ]
    ]
    "pt" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Artigo original</span>"
      "titulo" => "Pun&#231;&#227;o aspirativa transbr&#244;nquica guiada por ecoendoscopia br&#244;nquica no diagn&#243;stico e estadiamento de cancro do pulm&#227;o em 179 doentes"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => "pt"
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "192"
          "paginaFinal" => "199"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Endobronchial ultrasound-guided transbronchial needle aspiration for lung cancer diagnosis and staging in 179 patients"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "pt" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figura 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1002
              "Ancho" => 1500
              "Tamanyo" => 165293
            ]
          ]
          "descripcion" => array:1 [
            "pt" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Les&#227;o perif&#233;rica do lobo superior direito com esta&#231;&#227;o ganglionar 2<span class="elsevierStyleHsp" style=""></span>R positiva na PET <span class="elsevierStyleBold">&#40;A&#41;</span>&#59; agulha no interior de g&#226;nglio mediast&#237;nico hipoecog&#233;nico heterog&#233;neo com dimens&#245;es aumentadas <span class="elsevierStyleBold">&#40;B&#41;</span>&#59; diagn&#243;stico citol&#243;gico de adenocarcinoma do pulm&#227;o 400&#160;x <span class="elsevierStyleBold">&#40;C&#41;</span>&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; Bugalho, D&#46; Ferreira, R&#46; Barata, C&#46; Rodrigues, S&#46;S&#46; Dias, F&#46; Medeiros, L&#46; Carreiro"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Bugalho"
            ]
            1 => array:2 [
              "nombre" => "D&#46;"
              "apellidos" => "Ferreira"
            ]
            2 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Barata"
            ]
            3 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Rodrigues"
            ]
            4 => array:2 [
              "nombre" => "S&#46;S&#46;"
              "apellidos" => "Dias"
            ]
            5 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Medeiros"
            ]
            6 => array:2 [
              "nombre" => "L&#46;"
              "apellidos" => "Carreiro"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215913000585?idApp=UINPBA00004E"
    "url" => "/08732159/0000001900000005/v3_201509041357/S0873215913000585/v3_201509041357/pt/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S0873215913000949"
    "issn" => "08732159"
    "doi" => "10.1016/j.rppneu.2013.07.002"
    "estado" => "S300"
    "fechaPublicacion" => "2013-09-01"
    "aid" => "171"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "edi"
    "cita" => "Rev Port Pneumol. 2013;19:189"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4093
      "formatos" => array:3 [
        "EPUB" => 272
        "HTML" => 2688
        "PDF" => 1133
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>"
      "titulo" => "Impact factor 0&#46;562 &#8211; The ultimate goal or the next step forward&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "189"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Fator de impacto de 0&#44;562- um objectivo ou uma etapa&#63;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 770
              "Ancho" => 1573
              "Tamanyo" => 117506
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Impact factors&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; Morais"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Morais"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215913000949?idApp=UINPBA00004E"
    "url" => "/08732159/0000001900000005/v3_201509041357/S0873215913000949/v3_201509041357/en/main.assets"
  ]
  "en" => array:11 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>"
    "titulo" => "Access to the mediastinum&#8212;The standard has changed"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "190"
        "paginaFinal" => "191"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "F&#46;J&#46;F&#46; Herth"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "F&#46;J&#46;F&#46;"
            "apellidos" => "Herth"
            "email" => array:1 [
              0 => "felix&#46;herth&#64;thoraxklinik-heidelberg&#46;de"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Department of Pneumology and Critical Care Medicine&#44; Thoraxklinik Heidelberg&#44; German Center for Lung Research&#44; University of Heidelberg&#44; Heidelberg&#44; Germany"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Abordagem do Mediastino&#8212;A norma foi alterada"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">100 years ago&#44; lung cancer was a rare disease&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Over time it has become one of the leading causes of cancer death worldwide&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Along with this the diagnostic and also the therapeutic implications have changed several times over the last few decades&#46; In 1968 the first TNM description was published&#44; trying to standardize the tumor staging and thereby the specific therapeutic recommendations&#46; Today the 7th edition of the TNM system is still in use and the fact that the staging of the mediastinum is one of the most important topics has still not been challenged&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">In 1964 Werner Maa&#223;en published his first full report about mediastinoscopy as a staging technique and in the following years the technique was established as the gold standard for the mediastinum&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Even after the implementation of improved imaging techniques like computer tomography &#40;CT&#41; and Positron emissions tomography &#40;PET&#41;&#44; the surgical option was not discussed&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Watching and learning from gastroenterologists&#44; Olympus Medical introduced the world&#39;s first curved linear array ultrasonic bronchoscope in 2004&#46; The development of the endoscope had started more than 5 years earlier based on a request to minimise existing EUS-FNA technology so that can be used for diagnosis from within the bronchial system&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">The success story of EBUS-TBNA starts in 2003 with the publication in the journal <span class="elsevierStyleItalic">Thorax</span> by Krasnik and Vilmann&#44;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> followed by an article by Yasufuku in <span class="elsevierStyleItalic">Chest</span>&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> Both articles gave an initial description of the principle of EBUS-TBNA&#46; In 2006&#44; the biggest case series on 502 patients showed that EBUS-TBNA resulted in 93&#37; diagnostic yield&#44; a sensitivity of 94&#37;&#44; specificity of 100&#37; and accuracy of 94&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Over the last ten years the evidence about EBUS-TBNA has grown rapidly and after several meta-analyses<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">8&#8211;10</span></a> the endoscopic technique is quoted now as the first test for evaluation of the mediastinum&#44; replacing mediastinoscopy&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">In this issue Dr&#46; Bugalho<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> writes about his experience with this method in Portugal&#46; The paper nicely demonstrates that there has been a rapid learning curve&#59; the results achieved are consistent with previous published results and&#44; especially in relation to the initial results&#44; the negative predicted value has increased dramatically&#46; Particularly in line with the most recent publications on this topic&#44;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">13&#8211;16</span></a> it is clear that nowadays not only have the tissue samplers been adapted to the new technique&#44; but also the tissue readers&#44; mainly cytopathologist&#44; primed to read cells instead of tissue&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">And today&#63; As mentioned&#44; EBUS-TBNA has become the Gold standard for diagnosing and staging the mediastinum&#46; But we still need to get better&#46; Due to modern oncological options&#44; cell analysis is no longer enough&#46; Molecular staging will become the future standard and therefore we have to work on our techniques&#44; to provide sufficient material for such questions&#46;But for the moment&#44; endobronchial ultrasound has replaced mediastinoscopy&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:16 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Smoking and health"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46;M&#46; Fletcher"
                            1 => "D&#46; Horn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "WHO Chron"
                        "fecha" => "1970"
                        "volumen" => "24"
                        "paginaInicial" => "345"
                        "paginaFinal" => "370"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4917569"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cancer statistics&#44; 2013"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46; Siegel"
                            1 => "D&#46; Naishadham"
                            2 => "A&#46; Jemal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3322/caac.21166"
                      "Revista" => array:6 [
                        "tituloSerie" => "CA"
                        "fecha" => "2013"
                        "volumen" => "63"
                        "paginaInicial" => "11"
                        "paginaFinal" => "30"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23335087"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The revised TNM staging system for lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46; Rami-Porta"
                            1 => "J&#46;J&#46; Crowley"
                            2 => "P&#46; Goldstraw"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Cardiovasc Surg"
                        "fecha" => "2009"
                        "volumen" => "15"
                        "paginaInicial" => "4"
                        "paginaFinal" => "9"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19262443"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Indications and preliminary results in 300 mediastinoscopies"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "W&#46; Maassen"
                            1 => "M&#46; Kirsch"
                            2 => "M&#46; Thuemmler"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Prax Pneumol"
                        "fecha" => "1964"
                        "volumen" => "18"
                        "paginaInicial" => "65"
                        "paginaFinal" => "77"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14174604"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Preliminary experience with a new method of endoscopic transbronchial real time ultrasound guided biopsy for diagnosis of mediastinal and hilar lesions"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; Krasnik"
                            1 => "P&#46; Vilmann"
                            2 => "S&#46;S&#46; Larsen"
                            3 => "G&#46;K&#46; Jacobsen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "2003"
                        "volumen" => "58"
                        "paginaInicial" => "1083"
                        "paginaFinal" => "1086"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14645981"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Real-time endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46; Yasufuku"
                            1 => "M&#46; Chiyo"
                            2 => "Y&#46; Sekine"
                            3 => "P&#46;N&#46; Chhajed"
                            4 => "K&#46; Shibuya"
                            5 => "T&#46; Iizasa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.126.1.122"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2004"
                        "volumen" => "126"
                        "paginaInicial" => "122"
                        "paginaFinal" => "128"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15249452"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Real-time endobronchial ultrasound guided transbronchial needle aspiration for sampling mediastinal lymph nodes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "F&#46;J&#46;F&#46; Herth"
                            1 => "R&#46; Eberhardt"
                            2 => "P&#46; Vilmann"
                            3 => "M&#46; Krasnik"
                            4 => "A&#46; Ernst"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/thx.2005.047829"
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "2006"
                        "volumen" => "61"
                        "paginaInicial" => "795"
                        "paginaFinal" => "798"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16738038"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Endobronchial ultrasound-guided transbronchial needle aspiration cytology&#58; a state of the art review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;E&#46; Cameron"
                            1 => "R&#46;S&#46; Andrade"
                            2 => "Pambuccian SE"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-2303.2009.00722.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Cytopathology"
                        "fecha" => "2010"
                        "volumen" => "21"
                        "paginaInicial" => "6"
                        "paginaFinal" => "26"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20015257"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Test performance of endobronchial ultrasound and transbronchial needle aspiration biopsy for mediastinal staging in patients with lung cancer&#58; systematic review and meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "K&#46; Adams"
                            1 => "P&#46;L&#46; Shah"
                            2 => "L&#46; Edmonds"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/thx.2008.109868"
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "2009"
                        "volumen" => "64"
                        "paginaInicial" => "757"
                        "paginaFinal" => "762"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19454408"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effectiveness and safety of endobronchial ultrasound&#8212;transbronchial needle aspiration&#58; a systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "L&#46; Varela-Lema"
                            1 => "A&#46; Fernandez-Villar"
                            2 => "A&#46; Ruano-Ravina"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09031936.00097908"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2009"
                        "volumen" => "33"
                        "paginaInicial" => "1156"
                        "paginaFinal" => "1164"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19407050"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Methods for staging non-small cell lung cancer&#46; Diagnosis and management of lung cancer&#44; 3rd ed&#46;&#58; American College of Chest Physicians Evidence-Based Clinical Practice Guidelines"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "G&#46;A&#46; Silvestri"
                            1 => "A&#46;V&#46; Gonzalez"
                            2 => "M&#46;A&#46; Jantz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.12-2355"
                      "Revista" => array:8 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2013"
                        "volumen" => "143"
                        "numero" => "Suppl&#46;"
                        "paginaInicial" => "e211S"
                        "paginaFinal" => "e250S"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23649440"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S016882780700637X"
                          "estado" => "S300"
                          "issn" => "01688278"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Endobronchial ultrasound-guided transbronchial needle aspiration for lung cancer diagnosis and staging in 179 patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Bugalho"
                            1 => "D&#46; Ferreira"
                            2 => "R&#46; Barata"
                            3 => "C&#46; Rodrigues"
                            4 => "S&#46;S&#46; Dias"
                            5 => "F&#46; Medeiros"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:2 [
                        "tituloSerie" => "Portuguese J Pulmonol"
                        "fecha" => "2013"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Combined endoesophageal&#8211;endobronchial ultrasound-guided&#44; fine-needle aspiration of mediastinal lymph nodes through a single bronchoscope in 150 patients with suspected lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "F&#46;J&#46; Herth"
                            1 => "M&#46; Krasnik"
                            2 => "N&#46; Kahn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.09-2149"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2010"
                        "volumen" => "138"
                        "paginaInicial" => "790"
                        "paginaFinal" => "794"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20154073"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Transbronchial and transesophageal fine needle aspiration using an ultrasound bronchoscope in mediastinal staging of potentially operable lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B&#46; Hwangbo"
                            1 => "G&#46;K&#46; Lee"
                            2 => "H&#46;S&#46; Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.09-2100"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2010"
                        "volumen" => "138"
                        "paginaInicial" => "795"
                        "paginaFinal" => "802"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20348194"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Rapid on-site cytologic evaluation during endobronchial ultrasound-guided transbronchial needle aspiration for diagnosing lung cancer&#58; a randomized study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Oki"
                            1 => "H&#46; Saka"
                            2 => "C&#46; Kitagawa"
                            3 => "Y&#46; Kogure"
                            4 => "N&#46; Murata"
                            5 => "T&#46; Adachi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000346987"
                      "Revista" => array:6 [
                        "tituloSerie" => "Respiration"
                        "fecha" => "2013"
                        "volumen" => "85"
                        "paginaInicial" => "486"
                        "paginaFinal" => "492"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23571718"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Greater physician involvement improves coding outcomes in endobronchial ultrasound-guided transbronchial needle aspiration procedures"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46; Pillai"
                            1 => "A&#46;R&#46; Medford"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000346574"
                      "Revista" => array:6 [
                        "tituloSerie" => "Respiration"
                        "fecha" => "2013"
                        "volumen" => "85"
                        "paginaInicial" => "417"
                        "paginaFinal" => "421"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23486226"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/08732159/0000001900000005/v3_201509041357/S0873215913000858/v3_201509041357/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9595"
    "tipo" => "SECCION"
    "pt" => array:2 [
      "titulo" => "Editoriais"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "pt"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/08732159/0000001900000005/v3_201509041357/S0873215913000858/v3_201509041357/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215913000858?idApp=UINPBA00004E"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Editorial
Access to the mediastinum—The standard has changed
Abordagem do Mediastino—A norma foi alterada
F.J.F. Herth
Department of Pneumology and Critical Care Medicine, Thoraxklinik Heidelberg, German Center for Lung Research, University of Heidelberg, Heidelberg, Germany
Read
8563
Times
was read the article
2882
Total PDF
5681
Total HTML
Share statistics
 array:24 [
  "pii" => "S0873215913000858"
  "issn" => "08732159"
  "doi" => "10.1016/j.rppneu.2013.07.001"
  "estado" => "S300"
  "fechaPublicacion" => "2013-09-01"
  "aid" => "170"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2013"
  "documento" => "simple-article"
  "crossmark" => 0
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "edi"
  "cita" => "Rev Port Pneumol. 2013;19:190-1"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 4670
    "formatos" => array:3 [
      "EPUB" => 276
      "HTML" => 3257
      "PDF" => 1137
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S0873215913000585"
    "issn" => "08732159"
    "doi" => "10.1016/j.rppneu.2012.10.006"
    "estado" => "S300"
    "fechaPublicacion" => "2013-09-01"
    "aid" => "160"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Pneumol. 2013;19:192-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 8864
      "formatos" => array:3 [
        "EPUB" => 282
        "HTML" => 6415
        "PDF" => 2167
      ]
    ]
    "pt" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Artigo original</span>"
      "titulo" => "Pun&#231;&#227;o aspirativa transbr&#244;nquica guiada por ecoendoscopia br&#244;nquica no diagn&#243;stico e estadiamento de cancro do pulm&#227;o em 179 doentes"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => "pt"
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "192"
          "paginaFinal" => "199"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Endobronchial ultrasound-guided transbronchial needle aspiration for lung cancer diagnosis and staging in 179 patients"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "pt" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figura 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1002
              "Ancho" => 1500
              "Tamanyo" => 165293
            ]
          ]
          "descripcion" => array:1 [
            "pt" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Les&#227;o perif&#233;rica do lobo superior direito com esta&#231;&#227;o ganglionar 2<span class="elsevierStyleHsp" style=""></span>R positiva na PET <span class="elsevierStyleBold">&#40;A&#41;</span>&#59; agulha no interior de g&#226;nglio mediast&#237;nico hipoecog&#233;nico heterog&#233;neo com dimens&#245;es aumentadas <span class="elsevierStyleBold">&#40;B&#41;</span>&#59; diagn&#243;stico citol&#243;gico de adenocarcinoma do pulm&#227;o 400&#160;x <span class="elsevierStyleBold">&#40;C&#41;</span>&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; Bugalho, D&#46; Ferreira, R&#46; Barata, C&#46; Rodrigues, S&#46;S&#46; Dias, F&#46; Medeiros, L&#46; Carreiro"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Bugalho"
            ]
            1 => array:2 [
              "nombre" => "D&#46;"
              "apellidos" => "Ferreira"
            ]
            2 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Barata"
            ]
            3 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Rodrigues"
            ]
            4 => array:2 [
              "nombre" => "S&#46;S&#46;"
              "apellidos" => "Dias"
            ]
            5 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Medeiros"
            ]
            6 => array:2 [
              "nombre" => "L&#46;"
              "apellidos" => "Carreiro"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215913000585?idApp=UINPBA00004E"
    "url" => "/08732159/0000001900000005/v3_201509041357/S0873215913000585/v3_201509041357/pt/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S0873215913000949"
    "issn" => "08732159"
    "doi" => "10.1016/j.rppneu.2013.07.002"
    "estado" => "S300"
    "fechaPublicacion" => "2013-09-01"
    "aid" => "171"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "edi"
    "cita" => "Rev Port Pneumol. 2013;19:189"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4093
      "formatos" => array:3 [
        "EPUB" => 272
        "HTML" => 2688
        "PDF" => 1133
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>"
      "titulo" => "Impact factor 0&#46;562 &#8211; The ultimate goal or the next step forward&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "189"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Fator de impacto de 0&#44;562- um objectivo ou uma etapa&#63;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 770
              "Ancho" => 1573
              "Tamanyo" => 117506
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Impact factors&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; Morais"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Morais"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215913000949?idApp=UINPBA00004E"
    "url" => "/08732159/0000001900000005/v3_201509041357/S0873215913000949/v3_201509041357/en/main.assets"
  ]
  "en" => array:11 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>"
    "titulo" => "Access to the mediastinum&#8212;The standard has changed"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "190"
        "paginaFinal" => "191"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "F&#46;J&#46;F&#46; Herth"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "F&#46;J&#46;F&#46;"
            "apellidos" => "Herth"
            "email" => array:1 [
              0 => "felix&#46;herth&#64;thoraxklinik-heidelberg&#46;de"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Department of Pneumology and Critical Care Medicine&#44; Thoraxklinik Heidelberg&#44; German Center for Lung Research&#44; University of Heidelberg&#44; Heidelberg&#44; Germany"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Abordagem do Mediastino&#8212;A norma foi alterada"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">100 years ago&#44; lung cancer was a rare disease&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Over time it has become one of the leading causes of cancer death worldwide&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Along with this the diagnostic and also the therapeutic implications have changed several times over the last few decades&#46; In 1968 the first TNM description was published&#44; trying to standardize the tumor staging and thereby the specific therapeutic recommendations&#46; Today the 7th edition of the TNM system is still in use and the fact that the staging of the mediastinum is one of the most important topics has still not been challenged&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">In 1964 Werner Maa&#223;en published his first full report about mediastinoscopy as a staging technique and in the following years the technique was established as the gold standard for the mediastinum&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Even after the implementation of improved imaging techniques like computer tomography &#40;CT&#41; and Positron emissions tomography &#40;PET&#41;&#44; the surgical option was not discussed&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Watching and learning from gastroenterologists&#44; Olympus Medical introduced the world&#39;s first curved linear array ultrasonic bronchoscope in 2004&#46; The development of the endoscope had started more than 5 years earlier based on a request to minimise existing EUS-FNA technology so that can be used for diagnosis from within the bronchial system&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">The success story of EBUS-TBNA starts in 2003 with the publication in the journal <span class="elsevierStyleItalic">Thorax</span> by Krasnik and Vilmann&#44;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> followed by an article by Yasufuku in <span class="elsevierStyleItalic">Chest</span>&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> Both articles gave an initial description of the principle of EBUS-TBNA&#46; In 2006&#44; the biggest case series on 502 patients showed that EBUS-TBNA resulted in 93&#37; diagnostic yield&#44; a sensitivity of 94&#37;&#44; specificity of 100&#37; and accuracy of 94&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Over the last ten years the evidence about EBUS-TBNA has grown rapidly and after several meta-analyses<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">8&#8211;10</span></a> the endoscopic technique is quoted now as the first test for evaluation of the mediastinum&#44; replacing mediastinoscopy&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">In this issue Dr&#46; Bugalho<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> writes about his experience with this method in Portugal&#46; The paper nicely demonstrates that there has been a rapid learning curve&#59; the results achieved are consistent with previous published results and&#44; especially in relation to the initial results&#44; the negative predicted value has increased dramatically&#46; Particularly in line with the most recent publications on this topic&#44;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">13&#8211;16</span></a> it is clear that nowadays not only have the tissue samplers been adapted to the new technique&#44; but also the tissue readers&#44; mainly cytopathologist&#44; primed to read cells instead of tissue&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">And today&#63; As mentioned&#44; EBUS-TBNA has become the Gold standard for diagnosing and staging the mediastinum&#46; But we still need to get better&#46; Due to modern oncological options&#44; cell analysis is no longer enough&#46; Molecular staging will become the future standard and therefore we have to work on our techniques&#44; to provide sufficient material for such questions&#46;But for the moment&#44; endobronchial ultrasound has replaced mediastinoscopy&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:16 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Smoking and health"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46;M&#46; Fletcher"
                            1 => "D&#46; Horn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "WHO Chron"
                        "fecha" => "1970"
                        "volumen" => "24"
                        "paginaInicial" => "345"
                        "paginaFinal" => "370"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4917569"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cancer statistics&#44; 2013"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46; Siegel"
                            1 => "D&#46; Naishadham"
                            2 => "A&#46; Jemal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3322/caac.21166"
                      "Revista" => array:6 [
                        "tituloSerie" => "CA"
                        "fecha" => "2013"
                        "volumen" => "63"
                        "paginaInicial" => "11"
                        "paginaFinal" => "30"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23335087"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The revised TNM staging system for lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46; Rami-Porta"
                            1 => "J&#46;J&#46; Crowley"
                            2 => "P&#46; Goldstraw"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Cardiovasc Surg"
                        "fecha" => "2009"
                        "volumen" => "15"
                        "paginaInicial" => "4"
                        "paginaFinal" => "9"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19262443"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Indications and preliminary results in 300 mediastinoscopies"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "W&#46; Maassen"
                            1 => "M&#46; Kirsch"
                            2 => "M&#46; Thuemmler"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Prax Pneumol"
                        "fecha" => "1964"
                        "volumen" => "18"
                        "paginaInicial" => "65"
                        "paginaFinal" => "77"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14174604"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Preliminary experience with a new method of endoscopic transbronchial real time ultrasound guided biopsy for diagnosis of mediastinal and hilar lesions"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; Krasnik"
                            1 => "P&#46; Vilmann"
                            2 => "S&#46;S&#46; Larsen"
                            3 => "G&#46;K&#46; Jacobsen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "2003"
                        "volumen" => "58"
                        "paginaInicial" => "1083"
                        "paginaFinal" => "1086"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14645981"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Real-time endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46; Yasufuku"
                            1 => "M&#46; Chiyo"
                            2 => "Y&#46; Sekine"
                            3 => "P&#46;N&#46; Chhajed"
                            4 => "K&#46; Shibuya"
                            5 => "T&#46; Iizasa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.126.1.122"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2004"
                        "volumen" => "126"
                        "paginaInicial" => "122"
                        "paginaFinal" => "128"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15249452"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Real-time endobronchial ultrasound guided transbronchial needle aspiration for sampling mediastinal lymph nodes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "F&#46;J&#46;F&#46; Herth"
                            1 => "R&#46; Eberhardt"
                            2 => "P&#46; Vilmann"
                            3 => "M&#46; Krasnik"
                            4 => "A&#46; Ernst"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/thx.2005.047829"
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "2006"
                        "volumen" => "61"
                        "paginaInicial" => "795"
                        "paginaFinal" => "798"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16738038"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Endobronchial ultrasound-guided transbronchial needle aspiration cytology&#58; a state of the art review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;E&#46; Cameron"
                            1 => "R&#46;S&#46; Andrade"
                            2 => "Pambuccian SE"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-2303.2009.00722.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Cytopathology"
                        "fecha" => "2010"
                        "volumen" => "21"
                        "paginaInicial" => "6"
                        "paginaFinal" => "26"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20015257"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Test performance of endobronchial ultrasound and transbronchial needle aspiration biopsy for mediastinal staging in patients with lung cancer&#58; systematic review and meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "K&#46; Adams"
                            1 => "P&#46;L&#46; Shah"
                            2 => "L&#46; Edmonds"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/thx.2008.109868"
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "2009"
                        "volumen" => "64"
                        "paginaInicial" => "757"
                        "paginaFinal" => "762"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19454408"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effectiveness and safety of endobronchial ultrasound&#8212;transbronchial needle aspiration&#58; a systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "L&#46; Varela-Lema"
                            1 => "A&#46; Fernandez-Villar"
                            2 => "A&#46; Ruano-Ravina"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09031936.00097908"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2009"
                        "volumen" => "33"
                        "paginaInicial" => "1156"
                        "paginaFinal" => "1164"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19407050"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Methods for staging non-small cell lung cancer&#46; Diagnosis and management of lung cancer&#44; 3rd ed&#46;&#58; American College of Chest Physicians Evidence-Based Clinical Practice Guidelines"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "G&#46;A&#46; Silvestri"
                            1 => "A&#46;V&#46; Gonzalez"
                            2 => "M&#46;A&#46; Jantz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.12-2355"
                      "Revista" => array:8 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2013"
                        "volumen" => "143"
                        "numero" => "Suppl&#46;"
                        "paginaInicial" => "e211S"
                        "paginaFinal" => "e250S"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23649440"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S016882780700637X"
                          "estado" => "S300"
                          "issn" => "01688278"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Endobronchial ultrasound-guided transbronchial needle aspiration for lung cancer diagnosis and staging in 179 patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Bugalho"
                            1 => "D&#46; Ferreira"
                            2 => "R&#46; Barata"
                            3 => "C&#46; Rodrigues"
                            4 => "S&#46;S&#46; Dias"
                            5 => "F&#46; Medeiros"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:2 [
                        "tituloSerie" => "Portuguese J Pulmonol"
                        "fecha" => "2013"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Combined endoesophageal&#8211;endobronchial ultrasound-guided&#44; fine-needle aspiration of mediastinal lymph nodes through a single bronchoscope in 150 patients with suspected lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "F&#46;J&#46; Herth"
                            1 => "M&#46; Krasnik"
                            2 => "N&#46; Kahn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.09-2149"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2010"
                        "volumen" => "138"
                        "paginaInicial" => "790"
                        "paginaFinal" => "794"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20154073"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Transbronchial and transesophageal fine needle aspiration using an ultrasound bronchoscope in mediastinal staging of potentially operable lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B&#46; Hwangbo"
                            1 => "G&#46;K&#46; Lee"
                            2 => "H&#46;S&#46; Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.09-2100"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2010"
                        "volumen" => "138"
                        "paginaInicial" => "795"
                        "paginaFinal" => "802"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20348194"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Rapid on-site cytologic evaluation during endobronchial ultrasound-guided transbronchial needle aspiration for diagnosing lung cancer&#58; a randomized study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Oki"
                            1 => "H&#46; Saka"
                            2 => "C&#46; Kitagawa"
                            3 => "Y&#46; Kogure"
                            4 => "N&#46; Murata"
                            5 => "T&#46; Adachi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000346987"
                      "Revista" => array:6 [
                        "tituloSerie" => "Respiration"
                        "fecha" => "2013"
                        "volumen" => "85"
                        "paginaInicial" => "486"
                        "paginaFinal" => "492"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23571718"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Greater physician involvement improves coding outcomes in endobronchial ultrasound-guided transbronchial needle aspiration procedures"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46; Pillai"
                            1 => "A&#46;R&#46; Medford"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000346574"
                      "Revista" => array:6 [
                        "tituloSerie" => "Respiration"
                        "fecha" => "2013"
                        "volumen" => "85"
                        "paginaInicial" => "417"
                        "paginaFinal" => "421"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23486226"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/08732159/0000001900000005/v3_201509041357/S0873215913000858/v3_201509041357/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9595"
    "tipo" => "SECCION"
    "pt" => array:2 [
      "titulo" => "Editoriais"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "pt"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/08732159/0000001900000005/v3_201509041357/S0873215913000858/v3_201509041357/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215913000858?idApp=UINPBA00004E"
]
Article information
ISSN: 08732159
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 8 10 18
2024 October 28 38 66
2024 September 47 29 76
2024 August 59 34 93
2024 July 46 36 82
2024 June 31 24 55
2024 May 35 41 76
2024 April 54 33 87
2024 March 49 33 82
2024 February 43 19 62
2024 January 32 29 61
2023 December 24 22 46
2023 November 34 45 79
2023 October 23 38 61
2023 September 23 34 57
2023 August 25 22 47
2023 July 22 29 51
2023 June 18 17 35
2023 May 35 30 65
2023 April 23 22 45
2023 March 40 23 63
2023 February 41 21 62
2023 January 21 22 43
2022 December 35 12 47
2022 November 52 32 84
2022 October 53 42 95
2022 September 24 26 50
2022 August 36 42 78
2022 July 39 41 80
2022 June 31 32 63
2022 May 28 28 56
2022 April 33 31 64
2022 March 40 59 99
2022 February 34 23 57
2022 January 60 34 94
2021 December 60 49 109
2021 November 64 32 96
2021 October 103 40 143
2021 September 34 31 65
2021 August 32 19 51
2021 July 15 21 36
2021 June 29 22 51
2021 May 41 39 80
2021 April 81 89 170
2021 March 62 31 93
2021 February 44 18 62
2021 January 40 31 71
2020 December 43 22 65
2020 November 36 22 58
2020 October 38 25 63
2020 September 53 25 78
2020 August 56 35 91
2020 July 70 30 100
2020 June 62 28 90
2020 May 72 32 104
2020 April 75 20 95
2020 March 59 19 78
2020 February 68 33 101
2020 January 74 32 106
2019 December 55 24 79
2019 November 72 29 101
2019 October 60 31 91
2019 September 64 21 85
2019 August 79 31 110
2019 July 77 27 104
2019 June 72 18 90
2019 May 131 33 164
2019 April 88 28 116
2019 March 124 12 136
2019 February 106 16 122
2019 January 74 18 92
2018 December 69 9 78
2018 November 20 0 20
2018 October 23 8 31
2018 September 20 9 29
2018 August 26 29 55
2018 July 33 22 55
2018 June 45 15 60
2018 May 52 18 70
2018 April 61 18 79
2018 March 89 16 105
2018 February 44 8 52
2018 January 83 18 101
2017 December 98 18 116
2017 November 21 20 41
2017 October 21 14 35
2017 September 19 20 39
2017 August 25 10 35
2017 July 21 15 36
2017 June 24 24 48
2017 May 29 13 42
2017 April 17 5 22
2017 March 15 13 28
2017 February 10 6 16
2017 January 15 3 18
2016 December 16 13 29
2016 November 10 5 15
2016 October 14 13 27
2016 September 9 6 15
2016 August 5 4 9
2016 July 5 6 11
2016 May 0 8 8
2016 April 16 3 19
2016 March 27 5 32
2016 February 35 16 51
2016 January 35 10 45
2015 December 38 9 47
2015 November 28 15 43
2015 October 11 15 26
2015 September 31 15 46
2015 August 26 8 34
2015 July 23 7 30
2015 June 15 3 18
2015 May 39 17 56
2015 April 42 11 53
2015 March 25 11 36
2015 February 24 15 39
2015 January 32 11 43
2014 December 34 8 42
2014 November 28 9 37
2014 October 23 13 36
2014 September 30 12 42
2014 August 22 6 28
2014 July 30 9 39
2014 June 34 9 43
2014 May 54 14 68
2014 April 55 13 68
2014 March 58 10 68
2014 February 48 16 64
2014 January 71 9 80
2013 December 47 22 69
2013 November 73 23 96
2013 October 82 36 118
2013 September 67 30 97
Show all

Follow this link to access the full text of the article

Pulmonology

Are you a health professional able to prescribe or dispense drugs?