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        "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">A s&#237;ndroma da veia cava superior &#40;SVCS&#41; &#233; causada por uma obstru&#231;&#227;o&#47;compress&#227;o gradual e insidiosa da veia cava superior&#44; caracterizando-se por f&#225;cies plet&#243;rica&#44; edema e ingurgitamento vascular do pesco&#231;o e parte superior do tronco&#46; &#201; geralmente tradutora de neoplasia&#44; sendo o cancro do pulm&#227;o a sua causa mais comum&#46;</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Objectivo&#58;</span> Estudo retrospectivo dos internamentos no Hospital de S&#46; Jo&#227;o entre Janeiro de 1995 e Dezembro de 2006 por SVCS de etiologia a esclarecer com a caracteriza&#231;&#227;o cl&#237;nica dos doentes e a avalia&#231;&#227;o de factores de progn&#243;stico&#46;</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Material e m&#233;todos&#58;</span> Foram seleccionados 60 doentes que &#224; data de admiss&#227;o n&#227;o tinham causa para SVCS&#46; Foram avaliados&#44; entre outros&#44; idade&#44; sexo&#44; exposi&#231;&#227;o e carga tab&#225;gica&#44; etiologia do SVCS&#44; tratamento e sobreviv&#234;ncia global&#46;</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Resultados&#58;</span> Dos doentes estudados&#44; 87&#37; apresentavam cancro do pulm&#227;o&#44; sendo o tipo histol&#243;gico mais comum o carcinoma pulmonar de pequenas c&#233;lulas &#40;CPPC&#41;&#44; com 41&#37; dos casos&#46; Em 10&#37; dos doentes foi diagnosticado linfoma n&#227;o Hodgkin&#46; Em rela&#231;&#227;o aos factores de progn&#243;stico estudados&#44; verificou-se que a aus&#234;ncia de metastiza&#231;&#227;o&#44; o diagn&#243;stico histol&#243;gico de linfoma&#44; o bom estado geral e a aus&#234;ncia de consumo tab&#225;gico se correlacionam positivamente de forma significativa com a sobreviv&#234;ncia&#46; Contrariamente&#44; o diagn&#243;stico de CPPC apresentou igualmente de forma significativa uma menor sobreviv&#234;ncia&#46;</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclus&#227;o&#58;</span> Nesta s&#233;rie de doentes com SVCS como apresenta&#231;&#227;o da doen&#231;a observou-se uma sobreviv&#234;ncia significativamente menor nos casos de CPPC&#44; doentes fumadores &#40;especialmente com<span class="elsevierStyleHsp" style=""></span>&#8805;<span class="elsevierStyleHsp" style=""></span>40 UMA&#41;&#44; naqueles com mau estado geral&#44; bem como nos que apresentavam uma maior progress&#227;o da doen&#231;a&#44; com presen&#231;a de metastiza&#231;&#227;o&#46;</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010&#59; XVI &#40;1&#41;&#58; 73-88</span></p></span>"
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        "titulo" => "Abstract"
        "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0035" class="elsevierStyleSimplePara elsevierViewall">Superior vena cava syndrome &#40;SVCS&#41; is characterised by gradual and insidious compression&#47;obstruction of the superior vena cava &#40;SVC&#41;&#46; Upper chest and neck ingurgitation&#44; plethoric face and oedema are the common symptoms&#47;signs&#46; It generally means the presence of neoplasm&#44; namely lung cancer&#46;</p><p id="sp0040" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Aim&#58;</span> Retrospective analysis of the patients admitted to S&#46; Jo&#227;o Hospital&#44; Porto&#44; Portugal&#44; January 1995-December 2006 with SVCS without previous diagnosis&#46; Patients&#44; tumour characteristics and prognostic factors were studied&#46;</p><p id="sp0045" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Material and methods&#58;</span> Data was collected by consulting the clinical files of 60 SVCS patients without previous diagnosis&#46; Data was gathered on the patients&#8217; demographic characteristics &#40;age&#44; gender&#44; smoking habits&#41;&#44; performance status&#44; histology&#44; staging&#44; treatment and overall survival&#46;</p><p id="sp0050" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Results&#58;</span> Lung cancer was observed in 87&#37; of the patients&#46; Small-cell lung cancer &#40;SCLC&#41; was the most frequent histological type&#59; 41&#37; of the patients&#46; It is noticeable that 10&#37; were diagnosed with non-Hodgkin&#8217;s lymphoma&#46; In terms of prognostic factors analysed&#44; the absence of metastasis&#44; the lymphoma&#8217;s histological diagnosis&#44; good performance status and non-smoker status were positively correlated with the survival rate&#46; On the contrary SCLC was significantly correlated with a worse survival&#46;</p><p id="sp0055" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclusions&#58;</span> In our analysis we concluded that SCLC&#44; smokers and a poorer performance status as well as metastatic disease were unfavourable prognostic factors to SVCS as tumour presentation&#46;</p><p id="sp0060" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010&#59; XVI &#40;1&#41;&#58; 73-88</span></p></span>"
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Artigo Original/Original Article
Síndroma da veia cava superior como apresentação de neoplasia
Superior vena cava syndrome as tumour presentation
Nuno Filipe Pires1,
Corresponding author
nunofxpires@gmail.com

Correspondência/Correspondence to: Serviço de Pneumologia, Hospital S. João, Alameda Prof. Hernâni Monteiro, 4202-451 Porto Telefone: 225512215
, António Morais2, Henrique Queiroga3
1 Interno Complementar de Pneumologia/Resident, Pulmonology
2 Assistente Hospitalar de Pneumologia/Consultant, Pulmonology
3 Chefe de Serviço de Pneumologia/Head of Pulmonology Hospital de S. João, Porto
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        "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">A s&#237;ndroma da veia cava superior &#40;SVCS&#41; &#233; causada por uma obstru&#231;&#227;o&#47;compress&#227;o gradual e insidiosa da veia cava superior&#44; caracterizando-se por f&#225;cies plet&#243;rica&#44; edema e ingurgitamento vascular do pesco&#231;o e parte superior do tronco&#46; &#201; geralmente tradutora de neoplasia&#44; sendo o cancro do pulm&#227;o a sua causa mais comum&#46;</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Objectivo&#58;</span> Estudo retrospectivo dos internamentos no Hospital de S&#46; Jo&#227;o entre Janeiro de 1995 e Dezembro de 2006 por SVCS de etiologia a esclarecer com a caracteriza&#231;&#227;o cl&#237;nica dos doentes e a avalia&#231;&#227;o de factores de progn&#243;stico&#46;</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Material e m&#233;todos&#58;</span> Foram seleccionados 60 doentes que &#224; data de admiss&#227;o n&#227;o tinham causa para SVCS&#46; Foram avaliados&#44; entre outros&#44; idade&#44; sexo&#44; exposi&#231;&#227;o e carga tab&#225;gica&#44; etiologia do SVCS&#44; tratamento e sobreviv&#234;ncia global&#46;</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Resultados&#58;</span> Dos doentes estudados&#44; 87&#37; apresentavam cancro do pulm&#227;o&#44; sendo o tipo histol&#243;gico mais comum o carcinoma pulmonar de pequenas c&#233;lulas &#40;CPPC&#41;&#44; com 41&#37; dos casos&#46; Em 10&#37; dos doentes foi diagnosticado linfoma n&#227;o Hodgkin&#46; Em rela&#231;&#227;o aos factores de progn&#243;stico estudados&#44; verificou-se que a aus&#234;ncia de metastiza&#231;&#227;o&#44; o diagn&#243;stico histol&#243;gico de linfoma&#44; o bom estado geral e a aus&#234;ncia de consumo tab&#225;gico se correlacionam positivamente de forma significativa com a sobreviv&#234;ncia&#46; Contrariamente&#44; o diagn&#243;stico de CPPC apresentou igualmente de forma significativa uma menor sobreviv&#234;ncia&#46;</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclus&#227;o&#58;</span> Nesta s&#233;rie de doentes com SVCS como apresenta&#231;&#227;o da doen&#231;a observou-se uma sobreviv&#234;ncia significativamente menor nos casos de CPPC&#44; doentes fumadores &#40;especialmente com<span class="elsevierStyleHsp" style=""></span>&#8805;<span class="elsevierStyleHsp" style=""></span>40 UMA&#41;&#44; naqueles com mau estado geral&#44; bem como nos que apresentavam uma maior progress&#227;o da doen&#231;a&#44; com presen&#231;a de metastiza&#231;&#227;o&#46;</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010&#59; XVI &#40;1&#41;&#58; 73-88</span></p></span>"
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        "titulo" => "Abstract"
        "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0035" class="elsevierStyleSimplePara elsevierViewall">Superior vena cava syndrome &#40;SVCS&#41; is characterised by gradual and insidious compression&#47;obstruction of the superior vena cava &#40;SVC&#41;&#46; Upper chest and neck ingurgitation&#44; plethoric face and oedema are the common symptoms&#47;signs&#46; It generally means the presence of neoplasm&#44; namely lung cancer&#46;</p><p id="sp0040" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Aim&#58;</span> Retrospective analysis of the patients admitted to S&#46; Jo&#227;o Hospital&#44; Porto&#44; Portugal&#44; January 1995-December 2006 with SVCS without previous diagnosis&#46; Patients&#44; tumour characteristics and prognostic factors were studied&#46;</p><p id="sp0045" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Material and methods&#58;</span> Data was collected by consulting the clinical files of 60 SVCS patients without previous diagnosis&#46; Data was gathered on the patients&#8217; demographic characteristics &#40;age&#44; gender&#44; smoking habits&#41;&#44; performance status&#44; histology&#44; staging&#44; treatment and overall survival&#46;</p><p id="sp0050" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Results&#58;</span> Lung cancer was observed in 87&#37; of the patients&#46; Small-cell lung cancer &#40;SCLC&#41; was the most frequent histological type&#59; 41&#37; of the patients&#46; It is noticeable that 10&#37; were diagnosed with non-Hodgkin&#8217;s lymphoma&#46; In terms of prognostic factors analysed&#44; the absence of metastasis&#44; the lymphoma&#8217;s histological diagnosis&#44; good performance status and non-smoker status were positively correlated with the survival rate&#46; On the contrary SCLC was significantly correlated with a worse survival&#46;</p><p id="sp0055" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclusions&#58;</span> In our analysis we concluded that SCLC&#44; smokers and a poorer performance status as well as metastatic disease were unfavourable prognostic factors to SVCS as tumour presentation&#46;</p><p id="sp0060" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010&#59; XVI &#40;1&#41;&#58; 73-88</span></p></span>"
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ISSN: 08732159
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