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        "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0035" class="elsevierStyleSimplePara elsevierViewall">A pneumonia adquirida na comunidade &#40;PAC&#41; &#233; a principal causa de s&#233;psis em cuidados intensivos de adultos&#46; Com o objectivo de caracterizar o quadro cl&#237;nico de PAC em cuidados intensivos&#44; tratamento e avalia&#231;&#227;o de factores progn&#243;sticos&#44; com especial relev&#226;ncia para a antibioterapia&#44; realizou-se um estudo retrospectivo dos doentes admitidos numa UCI polivalente com PAC&#44; de 1 de Junho de 2004 a 31 de Dezembro de 2006&#46; Analisaram-se 76 doentes com uma idade m&#233;dia de 62&#44;88 &#40;18&#44;75&#41; anos&#46; O APACHE II m&#233;dio de 24&#44;88 &#40;9&#44;75&#41; e o SAPS 2 m&#233;dio era de 51&#44;18 &#40;18&#44;05&#41;&#44; com mortalidade prevista de 47&#44;27&#37;&#46; O microrganismo respons&#225;vel foi identificado em 42&#44;1&#37; dos casos&#46; O agente etiol&#243;gico mais comum foi o <span class="elsevierStyleItalic">Streptococcus pneumoniae</span>&#44; mas o grupo de agentes etiol&#243;gicos mais frequentemente identificados foi o dos bacilos ent&#233;ricos gramnegativos&#46;</p><p id="sp0040" class="elsevierStyleSimplePara elsevierViewall">A antibioterapia pr&#233;via mais usada foi a levofloxacina&#46; O esquema de antibioterapia mais usado na admiss&#227;o foi a associa&#231;&#227;o ceftriaxone com azitromicina&#46; Em 32 doentes em que foi poss&#237;vel avaliar a adequa&#231;&#227;o terap&#234;utica&#44; 27 estavam sob esquemas de antibioterapia adequados&#46; Foram submetidos a ventila&#231;&#227;o mec&#226;nica 66 doentes &#40;86&#44;8&#37;&#41;&#44; com uma dura&#231;&#227;o mediana de 4 dias&#46; A demora mediana foi de 5&#44;3 dias&#46; A mortalidade na unidade foi de 36&#44;8&#37; e a hospitalar de 55&#44;26&#37;&#46;</p><p id="sp0045" class="elsevierStyleSimplePara elsevierViewall">O &#237;ndice SAPS 2&#44; o valor de PCR&#44; o pot&#225;ssio s&#233;rico e a antibioterapia inicial n&#227;o adequada relacionaram-se com maior mortalidade&#46; Ap&#243;s an&#225;lise multivariada&#44; apenas o &#237;ndice SAPS II manteve significado estat&#237;stico&#46;</p><p id="sp0050" class="elsevierStyleSimplePara elsevierViewall">O uso da antibioterapia deve ser criterioso&#44; tendo em conta os principais agentes e a sua susceptibilidade&#46;</p><p id="sp0055" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010&#59; XVI &#40;2&#41;&#58; 223-235</span></p></span>"
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Artigo Original/Original Article
Pneumonia adquirida na comunidade numa unidade de cuidados intensivos
Community-acquired pneumonia in an intensive care unit
M. Raquel Marques1, António Nunes2, Cristina Sousa3, Fausto Moura2, João Gouveia2, Armindo Ramos4,*
1 Interna do internato Complementar de Medicina Interna/Resident, Internal Medicine
2 Assistente de Medicina Interna, Intensivista/Consultant, Internal Medicine, Intensive Care
3 Assistente Hospitalar Graduada de Gastrenterologia, Intensivista/Consultant, Gastroenterology Specialist, Intensive Care
4 Assistente Hospitalar Graduado de Medicina Interna, Intensivista e Director da Unidade de Cuidados Intensivos Médico-Cirúrgicos/Consultant, Internal Medicine Specialist, Intensive Care, Medical-Surgical Intensive Care Unit
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        "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0035" class="elsevierStyleSimplePara elsevierViewall">A pneumonia adquirida na comunidade &#40;PAC&#41; &#233; a principal causa de s&#233;psis em cuidados intensivos de adultos&#46; Com o objectivo de caracterizar o quadro cl&#237;nico de PAC em cuidados intensivos&#44; tratamento e avalia&#231;&#227;o de factores progn&#243;sticos&#44; com especial relev&#226;ncia para a antibioterapia&#44; realizou-se um estudo retrospectivo dos doentes admitidos numa UCI polivalente com PAC&#44; de 1 de Junho de 2004 a 31 de Dezembro de 2006&#46; Analisaram-se 76 doentes com uma idade m&#233;dia de 62&#44;88 &#40;18&#44;75&#41; anos&#46; O APACHE II m&#233;dio de 24&#44;88 &#40;9&#44;75&#41; e o SAPS 2 m&#233;dio era de 51&#44;18 &#40;18&#44;05&#41;&#44; com mortalidade prevista de 47&#44;27&#37;&#46; O microrganismo respons&#225;vel foi identificado em 42&#44;1&#37; dos casos&#46; O agente etiol&#243;gico mais comum foi o <span class="elsevierStyleItalic">Streptococcus pneumoniae</span>&#44; mas o grupo de agentes etiol&#243;gicos mais frequentemente identificados foi o dos bacilos ent&#233;ricos gramnegativos&#46;</p><p id="sp0040" class="elsevierStyleSimplePara elsevierViewall">A antibioterapia pr&#233;via mais usada foi a levofloxacina&#46; O esquema de antibioterapia mais usado na admiss&#227;o foi a associa&#231;&#227;o ceftriaxone com azitromicina&#46; Em 32 doentes em que foi poss&#237;vel avaliar a adequa&#231;&#227;o terap&#234;utica&#44; 27 estavam sob esquemas de antibioterapia adequados&#46; Foram submetidos a ventila&#231;&#227;o mec&#226;nica 66 doentes &#40;86&#44;8&#37;&#41;&#44; com uma dura&#231;&#227;o mediana de 4 dias&#46; A demora mediana foi de 5&#44;3 dias&#46; A mortalidade na unidade foi de 36&#44;8&#37; e a hospitalar de 55&#44;26&#37;&#46;</p><p id="sp0045" class="elsevierStyleSimplePara elsevierViewall">O &#237;ndice SAPS 2&#44; o valor de PCR&#44; o pot&#225;ssio s&#233;rico e a antibioterapia inicial n&#227;o adequada relacionaram-se com maior mortalidade&#46; Ap&#243;s an&#225;lise multivariada&#44; apenas o &#237;ndice SAPS II manteve significado estat&#237;stico&#46;</p><p id="sp0050" class="elsevierStyleSimplePara elsevierViewall">O uso da antibioterapia deve ser criterioso&#44; tendo em conta os principais agentes e a sua susceptibilidade&#46;</p><p id="sp0055" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010&#59; XVI &#40;2&#41;&#58; 223-235</span></p></span>"
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        "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0060" class="elsevierStyleSimplePara elsevierViewall">Community-acquired pneumonia &#40;CAP&#41; is the leading cause of sepsis in adult critical care&#46;</p><p id="sp0065" class="elsevierStyleSimplePara elsevierViewall">We present a retrospective study of patients admitted to a polyvalent intensive care unit with CAP from 1<span class="elsevierStyleSup">st</span> June 2004 &#8211; 31<span class="elsevierStyleSup">st</span> December 2006&#46;</p><p id="sp0070" class="elsevierStyleSimplePara elsevierViewall">We analysed 76 patients with a mean age of 62&#46;88 &#40;18&#46;75&#41; years&#46; Mean APACHE II score was 24&#46;88 &#40;9&#46;75&#41;&#46; Mean SAPS II was 51&#46;18 &#40;18&#46;05&#41;&#44; with a predicted mortality of 47&#46;27&#37;&#46; Aetiology was identified in 42&#46;1&#37; of the patients&#46; <span class="elsevierStyleItalic">Streptococcus pneumoniae</span> was the most frequent aetiological agent&#44; but the group of aetiological agents more frequently identified was Gram-negative enteric bacilli&#46;</p><p id="sp0075" class="elsevierStyleSimplePara elsevierViewall">Levofloxacine was the most frequently previously used antibiotic&#46; The most frequently used antibiotherapy scheme was the association ceftriaxone &#8211; azithromicine&#46; It was possible to evaluate suitability of treatment in 32 patients&#59; 27 were on suitable antibiotherapy regimes&#46; 66 patients &#40;86&#46;8&#37;&#41; were on respirators&#44; with a median length of 4 days&#46; The median length of stay was 5&#46;3<span class="elsevierStyleHsp" style=""></span>days&#46; ICU mortality was 36&#46;8&#37; and hospital mortality 55&#46;26&#37;&#46;</p><p id="sp0080" class="elsevierStyleSimplePara elsevierViewall">SAPS II&#44; CRP &#40;C-reactive protein&#41;&#44; potassium and initial unsuitable antibiotherapy were related to mortality&#46; After multivariate analysis&#44; only SAPS II maintained statistical significance&#46;</p><p id="sp0085" class="elsevierStyleSimplePara elsevierViewall">Use of antibiotics should be judicious&#44; taking the most frequent agents and their susceptibility into consideration&#46;</p><p id="sp0090" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010&#59; XVI &#40;2&#41;&#58; 223-235</span></p></span>"
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Article information
ISSN: 08732159
Original language: Portuguese
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