Caso Clínico/Case Report
Pertussis ainda mata
Pertussis keeps on killing
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Apresentava na admissão hiperleucocitose e trombocitose. Foi transferido no segundo dia de internamento para o serviço de cuidados intensivos por agravamento clínico, tendo falecido cerca de 20 horas após admissão por hipertensão e hemorragia pulmonar. A tosse convulsa foi diagnosticada por PCR.</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall">Nos últimos anos, tem-se verificado um aumento do número de casos de tosse convulsa. Os adolescentes e adultos têm-se tornado numa fonte subreconhecida mas significativa de infecção, particularmente para os pequenos lactentes ainda sem a vacinação primária completa.</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">Os autores salientam a importância do reconhecimento da tosse convulsa, para que, mesmo nos seus quadros mais atípicos, se possa suspeitar, tratar, declarar e prevenir uma doença que não está nem se espera que esteja erradicada a curto ou médio prazo. São necessárias novas estratégias de vacinação para evitar esta doença, que pode ser fatal nos mais vulneráveis.</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010; XVI (2): 315-320</span></p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0035" class="elsevierStyleSimplePara elsevierViewall">Pertussis, or whooping cough, is a highly infectious respiratory disease, endemic all over the world, caused by bacteria <span class="elsevierStyleItalic">Bordetella pertussis</span>.</p><p id="sp0040" class="elsevierStyleSimplePara elsevierViewall">The authors describe the case of a 36 day old infant, brought to the emergency room due to respiratory distress and cyanosing cough, admitted with suspected pertussis infection complicated by bacterial pneumonia, having begun large spectrum antibiotics. Labs showed hyperleukocytosis and thrombocytosis. She was transferred to an Intensive Care Unit because of a worsened state, dying 20 hours after admission with pulmonary hypertension and haemorrhage. Pertussis was diagnosed by PCR.</p><p id="sp0045" class="elsevierStyleSimplePara elsevierViewall">Over the last few years, there has been an increase in the number of cases of pertussis. Adolescents and adults have become an under-recognized but significant source of infection, particularly to small unvaccinated infants.</p><p id="sp0050" class="elsevierStyleSimplePara elsevierViewall">The authors underline the importance of recognizing pertussis, so that even in its atypical presentation, one can suspect, treat, report and prevent a disease that is not, and is not expected to be, eradicated any time soon. New vaccination strategies are necessary, to avoid this disease, which can be fatal to the most vulnerable.</p><p id="sp0055" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010; XVI (2): 315-320</span></p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0025">Bibliografia</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:8 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "Kliegman Behrman" 1 => "Nelson Jenson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:5 [ "edicion" => "18" "titulo" => "Textbook of Pediatrics" "fecha" => "2007" "paginaInicial" => "1178" "paginaFinal" => "1182" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bb0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnosis and management of pertussis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Tozzi" 1 => "L. Celentano" 2 => "M. Atti" 3 => "S. Salmaso" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "JAMC" "fecha" => "2005" "volumen" => "172" "numero" => "4" "paginaInicial" => "509" "paginaFinal" => "515" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bb0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Azythromycin is as effective and better tolerated than erythromycin estolate for the treatment of pertussis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J. Langley" 1 => "S. Halperin" 2 => "F. Boucher" 3 => "B. Smith" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "2004" "volumen" => "114" "paginaInicial" => "e96" "paginaFinal" => "e101" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15231980" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bb0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "What is new in pertussis?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E. Bamberger" 1 => "I. Scrugo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00431-007-0548-2" "Revista" => array:6 [ "tituloSerie" => "Eur J Pediatr" "fecha" => "2008" "volumen" => "167" "paginaInicial" => "133" "paginaFinal" => "139" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17668241" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bb0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cost effectiveness of pertussis vaccination in adults" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:1 [ 0 => "Lee" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.amepre.2006.10.016" "Revista" => array:7 [ "tituloSerie" => "Am J Prev Med" "fecha" => "2007" "volumen" => "32" "numero" => "3" "paginaInicial" => "186" "paginaFinal" => "193" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17296470" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bb0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The case for maternal vaccination against pertussis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "F. Mooi" 1 => "S. Greeff" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Lancet Infec Dis" "fecha" => "2007" "volumen" => "7" "paginaInicial" => "614" "paginaFinal" => "624" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bb0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pertussis in infants: Preventing deaths and hospitalizations in the very young" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "N. Wood" 1 => "H. Quinn" 2 => "P. McIntyre" 3 => "E. Elliot" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1440-1754.2008.01292.x" "Revista" => array:6 [ "tituloSerie" => "Journal of Paediatrics and Child Health" "fecha" => "2008" "volumen" => "44" "paginaInicial" => "161" "paginaFinal" => "165" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18377367" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bb0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pertussis in adolescents and adults: should we vaccinate?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "G. Lee" 1 => "C. LeBaron" 2 => "T. Murphy" 3 => "S. Lett" 4 => "S. Schauer" 5 => "T. Lieu" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1542/peds.2004-2509" "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "2005" "volumen" => "115" "paginaInicial" => "1675" "paginaFinal" => "1684" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15930232" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "pt" "url" => "/08732159/0000001600000002/v1_201509151443/S0873215915300295/v1_201509151443/pt/main.assets" "Apartado" => array:4 [ "identificador" => "43360" "tipo" => "SECCION" "pt" => array:2 [ "titulo" => "Casos Clínicos/Cases Reports" "idiomaDefecto" => true ] "idiomaDefecto" => "pt" ] "PDF" => "https://static.elsevier.es/multimedia/08732159/0000001600000002/v1_201509151443/S0873215915300295/v1_201509151443/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915300295?idApp=UINPBA00004E" ]
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ISSN: 08732159Original language: Portuguese
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