Caso Clínico/Case Report
Esclerose tuberosa com envolvimento pulmonar
Tuberous sclerosis with pulmonary involvment
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"identificador" => "af0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cr0005" ] ] ] 1 => array:3 [ "nombre" => "Carla" "apellidos" => "Nogueira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "af0005" ] ] ] 2 => array:3 [ "nombre" => "Daniela" "apellidos" => "Ferreira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "af0010" ] ] ] 3 => array:3 [ "nombre" => "Sofia" "apellidos" => "Neves" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "af0010" ] ] ] 4 => array:3 [ "nombre" => "Natália" "apellidos" => "Taveira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "af0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Interna Complementar de Pneumologia" "etiqueta" => "1" "identificador" => "af0005" ] 1 => array:3 [ "entidad" => "Assistente Hospitalar de Pneumologia" "etiqueta" => "2" "identificador" => "af0010" ] 2 => array:3 [ "entidad" => "Assistente Hospitalar Graduada de Pneumologia CHVNG/Espinho EPE" "etiqueta" => "3" "identificador" => "af0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cr0005" "etiqueta" => "*" "correspondencia" => "<span class="elsevierStyleBold">Correspondência</span>: Susana Alves Ferreira, Rua Conceição Fernandes, Vilar de Andorinho, 4430-502 Vila Nova de Gaia, Portugal, Telefone: 00351912767155" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Tuberous sclerosis with pulmonary involvment" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-03-31" "fechaAceptado" => "2009-08-06" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec570150" "palabras" => array:3 [ 0 => "Angiomiolipoma" 1 => "esclerose tuberosa" 2 => "linfangioleiomiomatose" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec570151" "palabras" => array:3 [ 0 => "Tuberous sclerosis" 1 => "lymphangioleiomyomatosis" 2 => "angiomyolipoma" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">A esclerose tuberosa (ET) é uma doença rara, esporádica ou transmitida de forma autossómica dominante. Caracteriza-se pela tríade convulsões, atraso mental e angiofibromas faciais. O envolvimento pulmonar é raro e, quando ocorre, é mais frequente no sexo feminino. Os autores apresentam o caso de uma doente de 52 anos, não fumadora, com antecedentes conhecidos de epilepsia na infância e angiomiolipomas renais. Assintomática e sem alterações ao exame objectivo. Em tomografia do tórax realizada para avaliação da doença, foram detectadas formações microquísticas dispersas em ambos os campos pulmonares. Exame funcional respiratório normal. A ressonância magnética cerebral evidenciou tuberosidades corticais e nódulos subependimários calcificados. Concluiu-sepelo diagnóstico de ET (linfangioleiomiomatose, tuberosidades corticais, nódulos subependimários e angiomiolipomas renais). Os autores apresentam o caso pela raridade da doença e do envolvimento pulmonar, ainda que em fase assintomática.</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010; XVI (2): 339-344</span></p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Tuberous sclerosis (TS) is a rare, sporadic or autosomal dominant disease characterized by the triad of seizures, mental retardation and angiofibromas. Lungs are rarely involved in TS, and pulmonary involvement is almost always found in females. We report the case of a 52 year-old female, nonsmoker, with a history of seizures in childhood and renal angiomyolipomas. She presented no complaints and her physical exam was normal. Chest CT performed for the evaluation of the disease detected thin-walled pulmonary cysts in both lungs. Lung function tests were normal. Cortical tubers and calcified subependymal nodules were seen in cerebral magnetic resonance. Tuberous sclerosis was diagnosed (lymphangioleiomyomatosis, cortical tubers, calcified subependymal nodules and angiomyiolipomas). The authors present this case because of its rarity and the existence of pulmonary involvement, while still asymptomatic.</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010; XVI (2): 339-344</span></p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0025">Bibliografia</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Scléreuse tubéreuse des circonvolutions cérébrales. 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Travis" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1999" "volumen" => "115" "paginaInicial" => "1041" "paginaFinal" => "1052" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10208206" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bb0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tuberous sclerosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.R. Yates" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/sj.ejhg.5201625" "Revista" => array:7 [ "tituloSerie" => "Eur J Hum Genet" "fecha" => "2006" "volumen" => "14" "numero" => "10" "paginaInicial" => "1065" "paginaFinal" => "1073" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16868562" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "pt" "url" => "/08732159/0000001600000002/v1_201509151443/S0873215915300325/v1_201509151443/pt/main.assets" "Apartado" => array:4 [ "identificador" => "43360" "tipo" => "SECCION" "pt" => array:2 [ "titulo" => "Casos Clínicos/Cases Reports" "idiomaDefecto" => true ] "idiomaDefecto" => "pt" ] "PDF" => "https://static.elsevier.es/multimedia/08732159/0000001600000002/v1_201509151443/S0873215915300325/v1_201509151443/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915300325?idApp=UINPBA00004E" ]
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ISSN: 08732159Original language: Portuguese
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| 2024 November | 2 | 2 | 4 |
| 2024 October | 56 | 46 | 102 |
| 2024 September | 36 | 38 | 74 |
| 2024 August | 43 | 63 | 106 |
| 2024 July | 38 | 51 | 89 |
| 2024 June | 31 | 65 | 96 |
| 2024 May | 32 | 40 | 72 |
| 2024 April | 28 | 52 | 80 |
| 2024 March | 32 | 46 | 78 |
| 2024 February | 25 | 26 | 51 |
| 2024 January | 20 | 36 | 56 |
| 2023 December | 25 | 38 | 63 |
| 2023 November | 21 | 32 | 53 |
| 2023 October | 10 | 38 | 48 |
| 2023 September | 24 | 38 | 62 |
| 2023 August | 19 | 27 | 46 |
| 2023 July | 21 | 40 | 61 |
| 2023 June | 27 | 31 | 58 |
| 2023 May | 23 | 42 | 65 |
| 2023 April | 18 | 42 | 60 |
| 2023 March | 19 | 41 | 60 |
| 2023 February | 18 | 27 | 45 |
| 2023 January | 28 | 36 | 64 |
| 2022 December | 21 | 44 | 65 |
| 2022 November | 38 | 48 | 86 |
| 2022 October | 41 | 46 | 87 |
| 2022 September | 17 | 51 | 68 |
| 2022 August | 45 | 64 | 109 |
| 2022 July | 22 | 48 | 70 |
| 2022 June | 13 | 36 | 49 |
| 2022 May | 43 | 60 | 103 |
| 2022 April | 25 | 53 | 78 |
| 2022 March | 29 | 50 | 79 |
| 2022 February | 26 | 40 | 66 |
| 2022 January | 22 | 50 | 72 |
| 2021 December | 32 | 44 | 76 |
| 2021 November | 28 | 40 | 68 |
| 2021 October | 24 | 45 | 69 |
| 2021 September | 30 | 46 | 76 |
| 2021 August | 18 | 29 | 47 |
| 2021 July | 34 | 33 | 67 |
| 2021 June | 21 | 28 | 49 |
| 2021 May | 32 | 37 | 69 |
| 2021 April | 68 | 93 | 161 |
| 2021 March | 44 | 31 | 75 |
| 2021 February | 47 | 20 | 67 |
| 2021 January | 35 | 16 | 51 |
| 2020 December | 20 | 20 | 40 |
| 2020 November | 45 | 28 | 73 |
| 2020 October | 32 | 22 | 54 |
| 2020 September | 56 | 21 | 77 |
| 2020 August | 56 | 23 | 79 |
| 2020 July | 53 | 13 | 66 |
| 2020 June | 32 | 15 | 47 |
| 2020 May | 50 | 17 | 67 |
| 2020 April | 47 | 20 | 67 |
| 2020 March | 44 | 9 | 53 |
| 2020 February | 35 | 22 | 57 |
| 2020 January | 43 | 12 | 55 |
| 2019 December | 39 | 21 | 60 |
| 2019 November | 40 | 16 | 56 |
| 2019 October | 32 | 18 | 50 |
| 2019 September | 39 | 12 | 51 |
| 2019 August | 39 | 21 | 60 |
| 2019 July | 31 | 10 | 41 |
| 2019 June | 33 | 19 | 52 |
| 2019 May | 29 | 27 | 56 |
| 2019 April | 34 | 24 | 58 |
| 2019 March | 32 | 16 | 48 |
| 2019 February | 33 | 12 | 45 |
| 2019 January | 39 | 17 | 56 |
| 2018 December | 19 | 13 | 32 |
| 2018 November | 7 | 2 | 9 |
| 2018 October | 10 | 6 | 16 |
| 2018 September | 16 | 5 | 21 |
| 2018 August | 68 | 18 | 86 |
| 2018 July | 43 | 22 | 65 |
| 2018 June | 70 | 23 | 93 |
| 2018 May | 96 | 18 | 114 |
| 2018 April | 64 | 33 | 97 |
| 2018 March | 65 | 40 | 105 |
| 2018 February | 34 | 9 | 43 |
| 2018 January | 47 | 10 | 57 |
| 2017 December | 46 | 11 | 57 |
| 2017 November | 44 | 15 | 59 |
| 2017 October | 28 | 11 | 39 |
| 2017 September | 16 | 23 | 39 |
| 2017 August | 12 | 18 | 30 |
| 2017 July | 12 | 10 | 22 |
| 2017 June | 21 | 13 | 34 |
| 2017 May | 28 | 6 | 34 |
| 2017 April | 8 | 19 | 27 |
| 2017 March | 14 | 44 | 58 |
| 2017 February | 10 | 4 | 14 |
| 2017 January | 9 | 3 | 12 |
| 2016 December | 11 | 3 | 14 |
| 2016 November | 8 | 9 | 17 |
| 2016 October | 15 | 8 | 23 |
| 2016 September | 1 | 3 | 4 |
| 2016 August | 7 | 2 | 9 |
| 2016 July | 3 | 2 | 5 |
| 2016 May | 0 | 1 | 1 |
| 2016 April | 1 | 4 | 5 |
| 2016 March | 4 | 8 | 12 |
| 2016 February | 4 | 12 | 16 |
| 2016 January | 7 | 15 | 22 |
| 2015 December | 10 | 3 | 13 |
| 2015 November | 4 | 2 | 6 |
| 2015 October | 2 | 2 | 4 |
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