Correspondência/Correspondence to Inês Vaz Luís, Serviço de Oncologia Médica, Hospital de Santa Maria/Faculdade de Medicina de Lisboa, Av. Prof. Egas Moniz, 1643-035 Lisboa, Telefone/Telephone: 21-7985257, Telemóvel/Mobile: 91-9129631.
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Aguiar, M. Felizardo, A.C. Mendes, D. Moniz, R. Sotto-Mayor, A. Bugalho de Almeida" "autores" => array:6 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Aguiar" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Felizardo" ] 2 => array:2 [ "nombre" => "A.C." "apellidos" => "Mendes" ] 3 => array:2 [ "nombre" => "D." "apellidos" => "Moniz" ] 4 => array:2 [ "nombre" => "R." "apellidos" => "Sotto-Mayor" ] 5 => array:2 [ "nombre" => "A. Bugalho" "apellidos" => "de Almeida" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915300362?idApp=UINPBA00004E" "url" => "/08732159/0000001600000003/v1_201509151447/S0873215915300362/v1_201509151447/pt/main.assets" ] "pt" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Artigo Original/Original Article</span>" "titulo" => "Características clínicas de doentes com neoplasia do pulmão e neoplasias primárias síncronas ou metácronas com outras localizações" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "391" "paginaFinal" => "405" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Inês Vaz Luís, Rita Macedo, Encarnação Teixeira, Renato Sotto-Mayor, A. Bugalho de Almeida" "autores" => array:5 [ 0 => array:4 [ "nombre" => "Inês Vaz" "apellidos" => "Luís" "email" => array:1 [ 0 => "inesvazluis@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "af0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cr0005" ] ] ] 1 => array:3 [ "nombre" => "Rita" "apellidos" => "Macedo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "af0010" ] ] ] 2 => array:3 [ "nombre" => "Encarnação" "apellidos" => "Teixeira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "af0015" ] ] ] 3 => array:3 [ "nombre" => "Renato" "apellidos" => "Sotto-Mayor" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "af0020" ] ] ] 4 => array:3 [ "nombre" => "A. Bugalho" "apellidos" => "de Almeida" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">5</span>" "identificador" => "af0025" ] ] ] ] "afiliaciones" => array:5 [ 0 => array:3 [ "entidad" => "Interna do Serviço de Oncologia Médica, Hospital de Santa Maria (HSM) – Centro Hospitalar Lisboa Norte (CHLN)/Resident, Medical Oncology Unit, Hospital de Santa Maria (HSM), Centro Hospitalar Lisboa Norte (CHLN)" "etiqueta" => "1" "identificador" => "af0005" ] 1 => array:3 [ "entidad" => "Assistente Eventual de Pneumologia/Future Pulmonolgy Consultant" "etiqueta" => "2" "identificador" => "af0010" ] 2 => array:3 [ "entidad" => "Assistente Hospitalar Graduada de Pneumologia/Consultant, Pulmonology Specialist" "etiqueta" => "3" "identificador" => "af0015" ] 3 => array:3 [ "entidad" => "Chefe de Serviço de Pneumologia/Head, Pulmonology Unit" "etiqueta" => "4" "identificador" => "af0020" ] 4 => array:3 [ "entidad" => "Director de Serviço, Professor da Faculdade de Medicina da Universidade de Lisboa/Unit Director, <span class="elsevierStyleItalic">Professor, Medical School, Universidade de Lisboa</span> Serviço de Pneumologia I, HSM – CLHN, Lisboa" "etiqueta" => "5" "identificador" => "af0025" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cr0005" "etiqueta" => "*" "correspondencia" => "<span class="elsevierStyleBold">Correspondência/<span class="elsevierStyleItalic">Correspondence to</span></span> Inês Vaz Luís, Serviço de Oncologia Médica, Hospital de Santa Maria/Faculdade de Medicina de Lisboa, Av. Prof. Egas Moniz, 1643-035 Lisboa, Telefone/Telephone: 21-7985257, Telemóvel/Mobile: 91-9129631." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Clinical characteristics of patients with lung cancer and metachronous or synchronous tumours with other locations" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-07-27" "fechaAceptado" => "2009-09-30" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec570158" "palabras" => array:5 [ 0 => "Neoplasias múltiplas" 1 => "neoplasia metácrona" 2 => "neoplasia síncrona" 3 => "neoplasia do pulmão" 4 => "vigilância" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec570159" "palabras" => array:5 [ 0 => "Multiple cancers" 1 => "metachronous cancer" 2 => "synchronous cancer" 3 => "lung cancer" 4 => "follow-up" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">O cancro do pulmão é a causa mais comum de morte por doença oncológica. Os doentes com diagnóstico de neoplasia – qualquer que seja a localização – têm risco acrescido de desenvolver um segundo tumor. Pretendeu-se caracterizar uma população com neoplasia do pulmão e o diagnóstico síncrono ou metácrono de tumor primário com outra localização. Foi feito um estudo retrospectivo, referente ao período de 2000-2007, analisando-se os processos clínicos de doentes seguidos na Unidade de Pneumologia Oncológica do nosso hospital em que estavam referenciadas duas neoplasias. Dos doentes seguidos na Unidade (n=1046) no período referido, 4,2% (n=44) tinham evidência de duas neoplasias. A maioria (88,6%) dos doentes eram homens, com idade média elevada (70,1±10 anos). Oitenta e seis por cento (n=38) tinham hábitos tabágicos e 65,4% dos doentes com registo de história familiar de neoplasia (n=26) tinham história familiar relevante (n=17). A doença oncológica manifestou-se em primeiro lugar na próstata, cólon, cabeça e pescoço ou bexiga. O cancro do pulmão foi em geral a segunda neoplasia. O intervalo de tempo médio entre a primeira e a segunda neoplasia foi de 62,9±64,9 meses (max: 240, min: 0), sendo que geralmente a segunda neoplasia foi detectada em estádio avançado. A sobrevivência média foi de 8,6±8,24 meses (max: 32; min: 1), permanecendo vivos quatro doentes.</p><p id="sp0105" class="elsevierStyleSimplePara elsevierViewall">Os presentes dados levam-nos a sugerir vigilância clínica prolongada em doentes com diagnóstico prévio de cancro. Sugerimos um algoritmo que possibilite vigiar melhor estes doentes e estudo prospectivo para verificar se existem marcadores moleculares nesta população.</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010; XVI (3): 391-405</span></p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">Lung cancer is the leading form of cancer death worldwide. Cancer patients are at a high risk of developing a second cancer. The present study attempts to determine the characteristics of a population with lung cancer diagnosed with another cancer.</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall">We analysed records of patients from the Department of Lung Oncology of our hospital from 2000 to 2007 who were identified as having two or more tumours. We found 4.2% (n=44) multiple cancers among the registered cases (n=1046), 88.6% males, (high) mean age 70.1±10<span class="elsevierStyleHsp" style=""></span>years old. About 86% (n=38) of the patients were smokers or ex-smokers. From the patients with record of family history, 65.4% (n=17) had relevant family history of cancer. The majority of the first malignancy diagnosed was prostate, colon, head and neck and bladder.</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">Lung cancer was essentially the second malignancy. The mean time lag between the two diagnoses was 62.9±64.9<span class="elsevierStyleHsp" style=""></span>months (max. 240, min. 0), with the second cancer usually detected at an advanced stage. The mean survival of patients who had a second primary lung cancer was 8.6±8.24<span class="elsevierStyleHsp" style=""></span>months (max. 32, min. 1), with four patients still surviving.</p><p id="sp0125" class="elsevierStyleSimplePara elsevierViewall">Our results suggest that extended follow-up is needed in these patients, using screening strategies which follow international recommendations, and with control of carcinogenic risk factors such as smoking. We suggest a tailored risk algorithm and a further study to assess if there are particular molecular markers in these patients.</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010; XVI (3): 391-405</span></p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0025">Bibliografia/Bibliography</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:23 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Estimates of cancer incidence ad mortality in Europe in 2006" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Ferlay" 1 => "P. Autier" 2 => "M. Boniol" 3 => "M. Heanue" 4 => "M. Colombet" 5 => "P. 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Perng" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Lung Cancer" "fecha" => "2002" "volumen" => "35" "numero" => "2" "paginaInicial" => "189" "paginaFinal" => "194" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11804692" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bb0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical features and prognosis of multiple primary tumors of lung combined with other organs–report of 281 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S.Z. Yi" 1 => "D.C. Zhang" 2 => "Y.G. Wang" 3 => "K.L. 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Travis" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1158/1055-9965.EPI-06-0414" "Revista" => array:8 [ "tituloSerie" => "Cancer Epidemiol Biomarkers Prev" "fecha" => "2006" "volumen" => "15" "numero" => "11" "paginaInicial" => "2020" "paginaFinal" => "2026" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17057028" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0161642009006113" "estado" => "S300" "issn" => "01616420" ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bb0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Multiple primary cancer: an experience at the cancer institute hospital with special reference to colorectal cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Ueno" 1 => "T. Muto" 2 => "M. Oya" 3 => "H. Ota" 4 => "K. Azekura" 5 => "T. 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Original language: Portuguese
Year/Month | Html | Total | |
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2024 November | 0 | 1 | 1 |
2024 October | 34 | 41 | 75 |
2024 September | 31 | 28 | 59 |
2024 August | 41 | 33 | 74 |
2024 July | 32 | 36 | 68 |
2024 June | 34 | 29 | 63 |
2024 May | 25 | 31 | 56 |
2024 April | 31 | 28 | 59 |
2024 March | 36 | 26 | 62 |
2024 February | 23 | 18 | 41 |
2024 January | 16 | 21 | 37 |
2023 December | 25 | 20 | 45 |
2023 November | 15 | 18 | 33 |
2023 October | 18 | 24 | 42 |
2023 September | 31 | 25 | 56 |
2023 August | 13 | 25 | 38 |
2023 July | 28 | 34 | 62 |
2023 June | 15 | 14 | 29 |
2023 May | 24 | 21 | 45 |
2023 April | 26 | 18 | 44 |
2023 March | 22 | 23 | 45 |
2023 February | 16 | 20 | 36 |
2023 January | 20 | 21 | 41 |
2022 December | 23 | 17 | 40 |
2022 November | 41 | 39 | 80 |
2022 October | 29 | 25 | 54 |
2022 September | 17 | 41 | 58 |
2022 August | 45 | 44 | 89 |
2022 July | 18 | 42 | 60 |
2022 June | 20 | 39 | 59 |
2022 May | 37 | 34 | 71 |
2022 April | 21 | 35 | 56 |
2022 March | 26 | 34 | 60 |
2022 February | 32 | 34 | 66 |
2022 January | 19 | 40 | 59 |
2021 December | 30 | 33 | 63 |
2021 November | 16 | 39 | 55 |
2021 October | 32 | 42 | 74 |
2021 September | 30 | 30 | 60 |
2021 August | 16 | 26 | 42 |
2021 July | 31 | 28 | 59 |
2021 June | 11 | 25 | 36 |
2021 May | 22 | 22 | 44 |
2021 April | 49 | 54 | 103 |
2021 March | 33 | 12 | 45 |
2021 February | 40 | 14 | 54 |
2021 January | 25 | 15 | 40 |
2020 December | 41 | 10 | 51 |
2020 November | 43 | 14 | 57 |
2020 October | 31 | 16 | 47 |
2020 September | 56 | 18 | 74 |
2020 August | 47 | 25 | 72 |
2020 July | 66 | 19 | 85 |
2020 June | 44 | 10 | 54 |
2020 May | 56 | 22 | 78 |
2020 April | 59 | 12 | 71 |
2020 March | 50 | 12 | 62 |
2020 February | 37 | 14 | 51 |
2020 January | 50 | 14 | 64 |
2019 December | 41 | 27 | 68 |
2019 November | 50 | 12 | 62 |
2019 October | 56 | 15 | 71 |
2019 September | 39 | 20 | 59 |
2019 August | 58 | 18 | 76 |
2019 July | 42 | 18 | 60 |
2019 June | 43 | 9 | 52 |
2019 May | 31 | 28 | 59 |
2019 April | 52 | 19 | 71 |
2019 March | 40 | 10 | 50 |
2019 February | 73 | 10 | 83 |
2019 January | 62 | 19 | 81 |
2018 December | 18 | 15 | 33 |
2018 November | 5 | 0 | 5 |
2018 October | 8 | 6 | 14 |
2018 September | 15 | 6 | 21 |
2018 August | 46 | 20 | 66 |
2018 July | 31 | 23 | 54 |
2018 June | 45 | 20 | 65 |
2018 May | 58 | 17 | 75 |
2018 April | 48 | 42 | 90 |
2018 March | 44 | 36 | 80 |
2018 February | 26 | 10 | 36 |
2018 January | 34 | 25 | 59 |
2017 December | 44 | 15 | 59 |
2017 November | 43 | 20 | 63 |
2017 October | 36 | 22 | 58 |
2017 September | 30 | 10 | 40 |
2017 August | 20 | 13 | 33 |
2017 July | 16 | 6 | 22 |
2017 June | 23 | 14 | 37 |
2017 May | 32 | 8 | 40 |
2017 April | 7 | 2 | 9 |
2017 March | 12 | 3 | 15 |
2017 February | 10 | 2 | 12 |
2017 January | 12 | 4 | 16 |
2016 December | 11 | 5 | 16 |
2016 November | 10 | 4 | 14 |
2016 October | 12 | 7 | 19 |
2016 September | 3 | 2 | 5 |
2016 August | 5 | 1 | 6 |
2016 July | 3 | 5 | 8 |
2016 April | 1 | 3 | 4 |
2016 March | 7 | 5 | 12 |
2016 February | 4 | 9 | 13 |
2016 January | 12 | 4 | 16 |
2015 December | 12 | 4 | 16 |
2015 November | 3 | 2 | 5 |
2015 October | 2 | 3 | 5 |