Endereço para correspondência / Correspondence to: SQN 206 BLOCO J APT 503. CEP: 70844-100 – Brasília-DF – Brasil, Telefone: 061-32452503
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CEP: 70844-100 – Brasília-DF – Brasil, Telefone: 061-32452503" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Correlation of levels of obstruction in COPD with lactate and six-minute walk test" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-07-22" "fechaAceptado" => "2008-09-17" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec570508" "palabras" => array:4 [ 0 => "Doença pulmonar obstrutiva crónica" 1 => "lactato" 2 => "teste de esforço" 3 => "dessaturação ao exercício" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec570509" "palabras" => array:4 [ 0 => "Chronic obstructive pulmonary disease" 1 => "lactate" 2 => "exercise test" 3 => "exercise desaturation" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0035" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Contextualização</span>: A doença pulmonar obstrutiva crónica (DPOC), importante causa de morbimortalidade em todo mundo, leva não só ao comprometimento pulmonar, mas também a alterações sistémicas, com repercussões sobre músculos esqueléticos e a capacidade de realizar esforços, mensurável pelo teste de caminhada de seis minutos (TC6’).</p><p id="sp0040" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Objectivos</span>: correlacionar obstrução da DPOC com lactato de repouso, frequência cardíaca de repouso, bem como com distância percorrida. Correlacionar distância percorrida com gasometria e ainda correlacionar dessaturação ao TC6’ com lactato e frequência cardíaca pós-TC6’.</p><p id="sp0045" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Método:</span> Portadores de DPOC realizaram espirometria, gasometria e TC6’, que avaliou: distância percorrida, frequência cardíaca (FC), lactato capilar (Lct) pré e pós-TC6’, além de dessaturação ao TC6’.</p><p id="sp0050" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Resultados:</span> Foram avaliados 91 doentes abrangendo todos os graus de obstrução. Os parâmetros pós-TC6’, como FC e Lct, aumentaram de maneira significativa com a realização do mesmo. A queda da saturação da hemoglobina ao oxigénio diante do TC6’ também foi significativa. A análise de correlação significativa mostrou-se positiva entre VEF<span class="elsevierStyleInf">1</span> e distância percorrida, negativa entre VEF<span class="elsevierStyleInf">1</span> e FC de repouso e negativa entre distância percorrida e PaCO<span class="elsevierStyleInf">2</span>, sendo não significante para as demais variáveis.</p><p id="sp0055" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclusões:</span> A progressão da obstrução na DPOC, bem como valores maiores de PaCO<span class="elsevierStyleInf">2</span>, contribuem para a redução da distância percorrida no TC6’. O grau de obstrução na DPOC leva a alteração hemodinâmica com o aumento da frequência cardíaca de repouso destes doentes.</p><p id="sp0060" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2009; XV (1): 11-25</span></p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Chronic obstructive pulmonary disease (COPD) is a leading cause of morbid-mortality world wide, leading not only to pulmonary damage but also to multi-systemic impairment, with repercussions on skeletal muscles and the ability to undertake effort, as measured in the six-minute walk test (6-MWT).</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Aims</span>: To correlate the level of obstruction in COPD with lactate concentration and heart rate (HR) at rest, and distance walked. To correlate distance walked with blood gas analysis and correlate desaturation in 6-MWT with post 6-MWT lactate concentration and heart rate.</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Methods</span>: COPD patients underwent spirometry, blood gas analysis and 6-MWT to evaluate distance walked, heart rate, capillary lactate (CL) concentration pre– and post 6MWT, and desaturation with 6-MWT.</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Results</span>: 91 patients with all levels of obstruction were evaluated. HR and CL increased significantly post 6-MWT. The decrease in peripheral saturation of haemoglobin to oxygen observed with 6-MWT was also significant. The distance walked was shorter the greater the obstruction. The correlation analysis was significantly positive between FEV<span class="elsevierStyleInf">1</span> and distance walked, negative between FEV<span class="elsevierStyleInf">1</span> and HR at rest and negative between distance walked and PaCO<span class="elsevierStyleInf">2</span>, and not significant for the other variables.</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclusions</span>: Increased obstruction in COPD and higher PaCO<span class="elsevierStyleInf">2</span> values contribute to a reduction in distance walked in 6-MWT. The level of obstruction in COPD leads to a haemodynamic impairment with increased HR at rest of these patients.</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2009; XV (1): 11-25</span></p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0025">Bibliografia / Bibliography</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:30 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The body-mass index, airflow obstruction, dyspnea and exercise capacity index in chronic obstructive pulmonary Disease" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "B.R. Celli" 1 => "C.G. Cote" 2 => "J.M. 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"referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Altered glutamate metabolism is associated with reduced muscle glutathione levels in patients with emphysema" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M.P.K.J. Engelen" 1 => "A.M.W.J. Schols" 2 => "J.D. Does" 3 => "N.E.P. Deutz" 4 => "E.F.M. Wouters" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.161.1.9901031" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2000" "volumen" => "161" "paginaInicial" => "98" "paginaFinal" => "103" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10619804" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bb0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Exercise-induced lactate increase in relation to muscle substrates in patients with chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M.P.K.J. Engelen" 1 => "A.M.W.J. Schols" 2 => "J.D. Does" 3 => "H.R. Gosker" 4 => "N.E.P. Deuts" 5 => "E.F.M. Wouters" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.162.5.9910066" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2000" "volumen" => "162" "paginaInicial" => "1697" "paginaFinal" => "1704" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11069799" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bb0050" "etiqueta" => "10." 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Original language: Portuguese
Year/Month | Html | Total | |
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2024 November | 3 | 5 | 8 |
2024 October | 40 | 30 | 70 |
2024 September | 29 | 25 | 54 |
2024 August | 48 | 41 | 89 |
2024 July | 42 | 35 | 77 |
2024 June | 22 | 17 | 39 |
2024 May | 27 | 44 | 71 |
2024 April | 31 | 31 | 62 |
2024 March | 35 | 33 | 68 |
2024 February | 24 | 23 | 47 |
2024 January | 23 | 25 | 48 |
2023 December | 17 | 19 | 36 |
2023 November | 28 | 33 | 61 |
2023 October | 19 | 35 | 54 |
2023 September | 18 | 33 | 51 |
2023 August | 23 | 22 | 45 |
2023 July | 19 | 32 | 51 |
2023 June | 23 | 17 | 40 |
2023 May | 25 | 34 | 59 |
2023 April | 16 | 27 | 43 |
2023 March | 18 | 34 | 52 |
2023 February | 22 | 30 | 52 |
2023 January | 22 | 27 | 49 |
2022 December | 14 | 26 | 40 |
2022 November | 28 | 37 | 65 |
2022 October | 37 | 34 | 71 |
2022 September | 20 | 36 | 56 |
2022 August | 24 | 44 | 68 |
2022 July | 22 | 43 | 65 |
2022 June | 18 | 27 | 45 |
2022 May | 33 | 40 | 73 |
2022 April | 23 | 34 | 57 |
2022 March | 15 | 35 | 50 |
2022 February | 28 | 30 | 58 |
2022 January | 26 | 30 | 56 |
2021 December | 19 | 37 | 56 |
2021 November | 26 | 27 | 53 |
2021 October | 42 | 40 | 82 |
2021 September | 19 | 30 | 49 |
2021 August | 30 | 27 | 57 |
2021 July | 21 | 31 | 52 |
2021 June | 19 | 26 | 45 |
2021 May | 40 | 33 | 73 |
2021 April | 48 | 53 | 101 |
2021 March | 53 | 20 | 73 |
2021 February | 58 | 15 | 73 |
2021 January | 34 | 11 | 45 |
2020 December | 20 | 14 | 34 |
2020 November | 45 | 17 | 62 |
2020 October | 17 | 23 | 40 |
2020 September | 67 | 16 | 83 |
2020 August | 53 | 21 | 74 |
2020 July | 47 | 18 | 65 |
2020 June | 52 | 19 | 71 |
2020 May | 44 | 18 | 62 |
2020 April | 49 | 14 | 63 |
2020 March | 46 | 10 | 56 |
2020 February | 29 | 18 | 47 |
2020 January | 39 | 20 | 59 |
2019 December | 48 | 20 | 68 |
2019 November | 45 | 24 | 69 |
2019 October | 45 | 24 | 69 |
2019 September | 53 | 20 | 73 |
2019 August | 81 | 27 | 108 |
2019 July | 55 | 23 | 78 |
2019 June | 72 | 13 | 85 |
2019 May | 50 | 37 | 87 |
2019 April | 63 | 17 | 80 |
2019 March | 88 | 12 | 100 |
2019 February | 78 | 13 | 91 |
2019 January | 121 | 13 | 134 |
2018 December | 42 | 12 | 54 |
2018 November | 17 | 1 | 18 |
2018 October | 18 | 9 | 27 |
2018 September | 10 | 11 | 21 |
2018 August | 51 | 22 | 73 |
2018 July | 29 | 22 | 51 |
2018 June | 59 | 18 | 77 |
2018 May | 46 | 14 | 60 |
2018 April | 58 | 41 | 99 |
2018 March | 55 | 26 | 81 |
2018 February | 31 | 13 | 44 |
2018 January | 44 | 12 | 56 |
2017 December | 35 | 17 | 52 |
2017 November | 33 | 8 | 41 |
2017 October | 24 | 15 | 39 |
2017 September | 28 | 22 | 50 |
2017 August | 38 | 20 | 58 |
2017 July | 28 | 11 | 39 |
2017 June | 27 | 16 | 43 |
2017 May | 31 | 8 | 39 |
2017 April | 13 | 26 | 39 |
2017 March | 17 | 63 | 80 |
2017 February | 13 | 3 | 16 |
2017 January | 12 | 7 | 19 |
2016 December | 18 | 9 | 27 |
2016 November | 7 | 3 | 10 |
2016 October | 11 | 14 | 25 |
2016 September | 2 | 1 | 3 |
2016 August | 5 | 1 | 6 |
2016 July | 2 | 4 | 6 |
2016 June | 0 | 5 | 5 |
2016 May | 0 | 12 | 12 |
2016 April | 1 | 2 | 3 |
2016 March | 2 | 5 | 7 |
2016 February | 4 | 9 | 13 |
2016 January | 6 | 3 | 9 |
2015 December | 8 | 2 | 10 |
2015 November | 4 | 1 | 5 |
2015 October | 3 | 2 | 5 |