Centro Hospitalar de Trás-os-Montes e Alto Douro Av. da Noruega 5000 Vila Real
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A propósito de um caso clínico" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "121" "paginaFinal" => "127" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Bebiana Conde, Ana Fernandes, Manuel Cunha, Abel Afonso" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Bebiana" "apellidos" => "Conde" "email" => array:1 [ 0 => "bebianaconde@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "af0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cr0005" ] ] ] 1 => array:3 [ "nombre" => "Ana" "apellidos" => "Fernandes" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "af0010" ] ] ] 2 => array:3 [ "nombre" => "Manuel" "apellidos" => "Cunha" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "af0015" ] ] ] 3 => array:3 [ "nombre" => "Abel" "apellidos" => "Afonso" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "af0010" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Interna do Internato Complementar de Pneumologia" "etiqueta" => "1" "identificador" => "af0005" ] 1 => array:3 [ "entidad" => "Chefe de Serviço de Pneumologia" "etiqueta" => "2" "identificador" => "af0010" ] 2 => array:3 [ "entidad" => "Assistente Graduado de Hematologia Clínica" "etiqueta" => "3" "identificador" => "af0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cr0005" "etiqueta" => "*" "correspondencia" => "Centro Hospitalar de Trás-os-Montes e Alto Douro Av. da Noruega 5000 Vila Real" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Immunocytoma IgA. Case report" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-05-06" "fechaAceptado" => "2008-10-01" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec570513" "palabras" => array:3 [ 0 => "Imunocitoma" 1 => "linfoma não Hodgkin" 2 => "envolvimento pulmonar" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec570512" "palabras" => array:3 [ 0 => "Immunocytoma" 1 => "non-Hodgkin’s lymphoma" 2 => "pulmonary involvement" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">O imunocitoma é um linfoma não Hodgkin (LNH) de células B, com evolução habitualmente indolente. Representa aproximadamente 1-3% dos LNH e atinge habitualmente adultos com mais de 50 anos, podendo manifestar-se por adenomegalias, hepatomegalia, esplenomegalia e linfocitose em 15 a 30% dos casos. Raramente tem envolvimento pulmonar. Com frequência ocorrendo picos monoclonais de imunoglobulinas, séricos, frequentemente IgM e raramente IgA.</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall">Como exemplo desta patologia apresentamos o caso clínico de um doente do sexo masculino, 52 anos, com clínica de infecções respiratórias bacterianas de repetição, com necessidade de internamentos sucessivos, cuja investigação identificou um imunocitoma IgA, estádio IV.</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">Assumindo-se o diagnóstico de um linfoma indolente, decidiu-se iniciar terapêutica profiláctica com imunoglobulinas humanas poliespecíficas, tendo havido diminuição das infecções respiratórias. Posteriormente, a evidência de progressão do linfoma condicionou o início de poliquimioterapia, com o esquema ciclofosfamida, vincristina, prednisolona (CVP) e rituximab®, tendo-se alcançado uma resposta parcial, que se manteve durante dois anos.</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2009; XV (1): 121-127</span></p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">Immunocytoma is a non-Hodgkin’s indolent evolution B cell lymphoma. It accounts for approximately 1-3% of non-Hodgkin's limphomas and usually onsets in adults aged over 50 years old. It manifests as lymphadenopathy, splenomegaly, hepatomegaly and lymphcytosis in 15-30% of cases and is rarely seen with pulmonary involvement. Monocloncal peaks of serum immunoglobulin often occur. These are IgM and rarely IgA.</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall">We present as an example a male patient aged 52 years old, with recurrent respiratory infections. Clinical work-up identified an immunocytoma IgA stage IV. Diagnosing an indolent lymphoma, we prophylactic polyspecific human immunoglobulin to treat the respiratory infection. Evidence of lymphoma progression leads us to prescribe combined cyclo-phosphamide (C), vincristine (V), prednisone (P) e rituximab (R) (CVP-R), which has obtained a partial response over two years.</p><p id="sp0035" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2009; XV (1): 121-127</span></p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0025">Bibliografia</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary immunocytoma with massive crystal storing histiocytosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.L. Prasad" 1 => "D.A. Charney" 2 => "J. Sarlin" 3 => "S.M. Keller" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Am J Surg Pathol" "fecha" => "1998" "volumen" => "22" "numero" => "9" "paginaInicial" => "1148" "paginaFinal" => "1153" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9737249" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bb0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphoproliferative diseases: non Hodgkin`s lymphoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.J. Densmore" 1 => "M.E. Williams" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "ASH-SAP American Society of Hematology Self-Assessment Program" "paginaInicial" => "205" "paginaFinal" => "226" "edicion" => "1" "serieFecha" => "2003" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bb0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Indolent B-cell Lymphomas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Petryk" 1 => "B.A. Peterson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "American Cancer Society Atlas of Clinical Oncology Malignant Lymphomas" "paginaInicial" => "103" "paginaFinal" => "104" "edicion" => "1" "serieFecha" => "2002" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bb0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Coexistence of (Parcial) Immune defects and risk of recurrent respiratory infections" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:9 [ 0 => "X. Bossuyt" 1 => "L. Moens" 2 => "E. Van Hoeyveld" 3 => "A. Jeurissen" 4 => "G. Bogaert" 5 => "Kate Sauer" 6 => "M. Proesmans" 7 => "M. Raes" 8 => "K. Boek" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1373/clinchem.2007.075861" "Revista" => array:6 [ "tituloSerie" => "Clinical Chemistry" "fecha" => "2007" "volumen" => "53" "paginaInicial" => "124" "paginaFinal" => "130" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17110469" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bb0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphoplasmacytic lymphoma and Waldenström's macroglobulinemia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "P.M. Mauch" 1 => "J.O. Armitage" 2 => "B. Coiffier" 3 => "R. Dalla-Favera" 4 => "N.L. Harris" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Non Hodgkin`s lymphomas" "paginaInicial" => "263" "paginaFinal" => "273" "serieFecha" => "2004" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bb0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary lymphoma of the mucosa-associated lymphoid tissue type: report of a case with cytological, histological, immunophenotypical correlation, and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.W. Micael" 1 => "P.H. Richardson" 2 => "C.W. Boudreaux" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1186/1746-1596-9-148" "Revista" => array:6 [ "tituloSerie" => "An Diagn Pathol" "fecha" => "2005" "volumen" => "9" "paginaInicial" => "148" "paginaFinal" => "152" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25056281" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bb0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchoalveolar lavage fluid profiles in sarcoidosis, tuberculosis, Non-Hodgkin's and Hodgkin's disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Drent" 1 => "S.S. Wagenaar" 2 => "P.H. Mulder" 3 => "H. Van Velzen-Blad" 4 => "M. Diamant" 5 => "J.M. Van den Bosh" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "An evaluation of differences. Chest" "fecha" => "1994" "volumen" => "105" "paginaInicial" => "514" "paginaFinal" => "519" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7905815" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bb0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Detection of lymphomatous involvement of lung by bronchoalveolar lavage" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "N. Keicho" 1 => "I. Oka" 2 => "K. Takeuchi" 3 => "A. Yamane" 4 => "Y. Yazaki" 5 => "I. Yotsumoto" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1994" "volumen" => "105" "paginaInicial" => "458" "paginaFinal" => "462" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8306747" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bb0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphoplasmacytic lymphoma/immunocytoma:towards a disease-targeted treatment?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:13 [ 0 => "M. Clavio" 1 => "S. Quintino" 2 => "C. Venturino" 3 => "F. Ballerini" 4 => "R. Varaldo" 5 => "S. Gatto" 6 => "V. Galbusera" 7 => "A. Garrone" 8 => "R. Grasso" 9 => "L. Canepa" 10 => "M. Miglino" 11 => "I. Pierri" 12 => "M. Gobbi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Exp Clin Res" "fecha" => "2001" "volumen" => "20" "paginaInicial" => "351" "paginaFinal" => "358" ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bb0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T.M. Grogan" 1 => "M.A. Jaramillo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "titulo" => "Pathology of Non-Hodgkin Lymphoma" "fecha" => "2002" "editorial" => "American Cancer Society Atlas of Clinical Oncology, Malignant Lymphomas" ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "pt" "url" => "/08732159/0000001500000001/v1_201509151539/S0873215915301173/v1_201509151539/pt/main.assets" "Apartado" => array:4 [ "identificador" => "43360" "tipo" => "SECCION" "pt" => array:2 [ "titulo" => "Casos Clínicos/Cases Reports" "idiomaDefecto" => true ] "idiomaDefecto" => "pt" ] "PDF" => "https://static.elsevier.es/multimedia/08732159/0000001500000001/v1_201509151539/S0873215915301173/v1_201509151539/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915301173?idApp=UINPBA00004E" ]
Original language: Portuguese
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2020 December | 15 | 5 | 20 |
2020 November | 55 | 17 | 72 |
2020 October | 28 | 22 | 50 |
2020 September | 59 | 25 | 84 |
2020 August | 66 | 27 | 93 |
2020 July | 86 | 21 | 107 |
2020 June | 80 | 20 | 100 |
2020 May | 89 | 24 | 113 |
2020 April | 54 | 19 | 73 |
2020 March | 63 | 16 | 79 |
2020 February | 58 | 55 | 113 |
2020 January | 67 | 17 | 84 |
2019 December | 77 | 28 | 105 |
2019 November | 57 | 18 | 75 |
2019 October | 78 | 25 | 103 |
2019 September | 67 | 13 | 80 |
2019 August | 96 | 30 | 126 |
2019 July | 91 | 20 | 111 |
2019 June | 88 | 18 | 106 |
2019 May | 75 | 36 | 111 |
2019 April | 89 | 44 | 133 |
2019 March | 99 | 22 | 121 |
2019 February | 102 | 20 | 122 |
2019 January | 110 | 26 | 136 |
2018 December | 61 | 18 | 79 |
2018 November | 34 | 0 | 34 |
2018 October | 36 | 10 | 46 |
2018 September | 19 | 6 | 25 |
2018 August | 58 | 17 | 75 |
2018 July | 52 | 28 | 80 |
2018 June | 66 | 20 | 86 |
2018 May | 75 | 45 | 120 |
2018 April | 99 | 44 | 143 |
2018 March | 70 | 27 | 97 |
2018 February | 53 | 11 | 64 |
2018 January | 54 | 13 | 67 |
2017 December | 50 | 13 | 63 |
2017 November | 47 | 6 | 53 |
2017 October | 30 | 8 | 38 |
2017 September | 41 | 18 | 59 |
2017 August | 39 | 26 | 65 |
2017 July | 35 | 27 | 62 |
2017 June | 45 | 24 | 69 |
2017 May | 42 | 15 | 57 |
2017 April | 28 | 2 | 30 |
2017 March | 19 | 19 | 38 |
2017 February | 18 | 8 | 26 |
2017 January | 16 | 5 | 21 |
2016 December | 25 | 5 | 30 |
2016 November | 12 | 5 | 17 |
2016 October | 22 | 7 | 29 |
2016 September | 5 | 6 | 11 |
2016 August | 3 | 7 | 10 |
2016 July | 4 | 7 | 11 |
2016 June | 1 | 3 | 4 |
2016 May | 0 | 6 | 6 |
2016 April | 3 | 1 | 4 |
2016 March | 8 | 3 | 11 |
2016 February | 5 | 6 | 11 |
2016 January | 4 | 6 | 10 |
2015 December | 7 | 5 | 12 |
2015 November | 3 | 1 | 4 |
2015 October | 3 | 1 | 4 |