Caso Clínico/Case Report
Exacerbação aguda da fibrose pulmonar idiopática
Acute exacerbation of idiopathic pulmonary fibrosis
Natália Melo1,
, Carla Damas2, Conceição Souto Moura3, António Morais2
Corresponding author
nataliafmelo@hotmail.com
Natália Melo, Serviço de Pneumologia, Hospital de S. João, Alameda Professor Hernâni Monteiro, 4202-451 Porto Telefone: 919371855.
Natália Melo, Serviço de Pneumologia, Hospital de S. João, Alameda Professor Hernâni Monteiro, 4202-451 Porto Telefone: 919371855.
1 Interna Complementar de Pneumologia
2 Assistente Hospitalar de Pneumologia Serviço de Pneumologia do Hospital S. João – Director de Serviço: Prof. Dr. Venceslau Hespanhol
3 Assistente Hospitalar Graduada de Anatomia Patológica Serviço de Anatomia Patológica do Hospital S. João – Directora de Serviço: Prof. Dra. Fátima Carneiro
Read
8224
Timeswas read the article
3896
Total PDF
4328
Total HTML
Share statistics
array:24 [ "pii" => "S0873215915301331" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)30133-1" "estado" => "S350" "fechaPublicacion" => "2009-03-01" "aid" => "11" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "copyrightAnyo" => "2009" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "sco" "cita" => "Rev Port Pneumol. 2009;15:305-12" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3115 "formatos" => array:3 [ "EPUB" => 224 "HTML" => 1845 "PDF" => 1046 ] ] "itemSiguiente" => array:19 [ "pii" => "S0873215915301343" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)30134-3" "estado" => "S350" "fechaPublicacion" => "2009-03-01" "aid" => "12" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "sco" "cita" => "Rev Port Pneumol. 2009;15:313-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2607 "formatos" => array:3 [ "EPUB" => 220 "HTML" => 1455 "PDF" => 932 ] ] "pt" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Caso Clínico/Case Report</span>" "titulo" => "Alveolite alérgica extrínseca com expressão imunológica atípica" "tienePdf" => "pt" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "pt" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "313" "paginaFinal" => "318" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Extrinsic allergic alveolitis with an atypical immune expression" ] ] "contieneResumen" => array:2 [ "pt" => true "en" => true ] "contienePdf" => array:1 [ "pt" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Teresa Costa, Cidália Rodrigues, Ana Arrobas" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Teresa" "apellidos" => "Costa" ] 1 => array:2 [ "nombre" => "Cidália" "apellidos" => "Rodrigues" ] 2 => array:2 [ "nombre" => "Ana" "apellidos" => "Arrobas" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915301343?idApp=UINPBA00004E" "url" => "/08732159/0000001500000002/v1_201509151524/S0873215915301343/v1_201509151524/pt/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S087321591530132X" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)30132-X" "estado" => "S350" "fechaPublicacion" => "2009-03-01" "aid" => "10" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "rev" "cita" => "Rev Port Pneumol. 2009;15:295-304" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2187 "formatos" => array:3 [ "EPUB" => 213 "HTML" => 1322 "PDF" => 652 ] ] "pt" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Artigo de Revisão/Review Article</span>" "titulo" => "Teste tuberculínico. Como optimizar?" "tienePdf" => "pt" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "pt" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "295" "paginaFinal" => "304" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Tuberculin skin test. How to optimise?" ] ] "contieneResumen" => array:2 [ "pt" => true "en" => true ] "contienePdf" => array:1 [ "pt" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Raquel Duarte" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Raquel" "apellidos" => "Duarte" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S087321591530132X?idApp=UINPBA00004E" "url" => "/08732159/0000001500000002/v1_201509151524/S087321591530132X/v1_201509151524/pt/main.assets" ] "pt" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Caso Clínico/Case Report</span>" "titulo" => "Exacerbação aguda da fibrose pulmonar idiopática" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "305" "paginaFinal" => "312" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Natália Melo, Carla Damas, Conceição Souto Moura, António Morais" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Natália" "apellidos" => "Melo" "email" => array:1 [ 0 => "nataliafmelo@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "af0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cr0005" ] ] ] 1 => array:3 [ "nombre" => "Carla" "apellidos" => "Damas" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "af0010" ] ] ] 2 => array:3 [ "nombre" => "Conceição Souto" "apellidos" => "Moura" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "af0015" ] ] ] 3 => array:3 [ "nombre" => "António" "apellidos" => "Morais" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "af0010" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Interna Complementar de Pneumologia" "etiqueta" => "1" "identificador" => "af0005" ] 1 => array:3 [ "entidad" => "Assistente Hospitalar de Pneumologia Serviço de Pneumologia do Hospital S. João – Director de Serviço: Prof. Dr. Venceslau Hespanhol" "etiqueta" => "2" "identificador" => "af0010" ] 2 => array:3 [ "entidad" => "Assistente Hospitalar Graduada de Anatomia Patológica Serviço de Anatomia Patológica do Hospital S. João – Directora de Serviço: Prof. Dra. Fátima Carneiro" "etiqueta" => "3" "identificador" => "af0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cr0005" "etiqueta" => "*" "correspondencia" => "Natália Melo, Serviço de Pneumologia, Hospital de S. João, Alameda Professor Hernâni Monteiro, 4202-451 Porto Telefone: 919371855." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Acute exacerbation of idiopathic pulmonary fibrosis" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-04-11" "fechaAceptado" => "2008-11-07" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec570454" "palabras" => array:2 [ 0 => "Fibrose pulmonar idiopática" 1 => "exacerbação aguda" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec570453" "palabras" => array:2 [ 0 => "Idiopathic pulmonary fibrosis" 1 => "acute exacerbation" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Alguns doentes com fibrose pulmonar idiopática (FPI) apresentam durante a sua evolução fases de agravamento clínico sem causa conhecida, designadas como “exacerbação aguda” ou “fase acelerada” da doença (EA). Caracterizam-se pelo agravamento marcado da dispneia, hipoxemia e pelo aparecimento de novas opacidades pulmonares ou pelo agravamento das já existentes no estudo imagiológico. Os achados histológicos típicos são o dano alveolar difuso (DAD) sobreposto a alterações de pneumonia intersticial usual (UIP). Esta entidade clínica associa-se a uma mortalidade elevada, não havendo até ao momento nenhuma terapêutica de comprovada eficácia.</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall">Os autores descrevem os casos clínicos de cinco doentes que apresentaram alterações clínicas, funcionais e radiológicas sugestivas de EA-FPI, assim como o tratamento efectuado e a evolução observada, enquadrando-os na discussão das características normalmente apresentadas por esta entidade.</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2009; XV (2): 305-312</span></p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall">Some patients with Idiopathic Pulmonary Fibrosis (IPF) have disease accelerated deterioration without identifiable cause referred as “acute exacerbation” or “accelerated stage”. It is characterized by severe worsening of dyspnea, hypoxemia and new or progressive opacities on imaging studies. The typical histological findings are diffuse alveolar damage in addition to the features of usual interstitial pneumonia pattern. Mortality in this clinical entity is very high and no efficacious therapeutic have been described.</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">The authors describe the clinical, functional and radiological features, treatment and evolution of five patients with IPF acute exacerbation. A discussion will be carry out concerning the IPF acute exacerbation usual features comparing with the alterations noticed in those patients.</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2009; XV (2): 305-312</span></p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0025">Bibliografia</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:16 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Classification and natural history of idiopathic interstitial pneumonias" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D.S. Kim" 1 => "H.R. Collard" 2 => "T.E. King Jr." ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1513/pats.200601-005TK" "Revista" => array:6 [ "tituloSerie" => "The proceedings of the American Thoracic Society" "fecha" => "2006" "volumen" => "3" "paginaInicial" => "285" "paginaFinal" => "292" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16738191" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bb0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cryptogenic fibrosing alveolitis: a study of an indigenous African population" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "C. Smith" 1 => "C. Feldman" 2 => "H. Levy" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Respiration (Herrlisheim)" "fecha" => "1990" "volumen" => "57" "paginaInicial" => "364" "paginaFinal" => "371" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bb0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Idiopathic pulmonary fibrosis. Clinical relevance of pathologic classification" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.L. Katzenstein" 1 => "J.L. Myers" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.157.4.9707039" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1998" "volumen" => "157" "paginaInicial" => "1301" "paginaFinal" => "1315" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9563754" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bb0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Idiopathic pulmonary fibrosis: diagnosis and treatment. International Consensus Statement" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "American Thoracic Society / European Respiratory Society" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.161.2.ats3-00" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2000" "volumen" => "161" "paginaInicial" => "646" "paginaFinal" => "664" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10673212" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bb0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical deterioration in patients with idiopathic pulmonary fibrosis: causes and assessment" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "R.J. Panos" 1 => "R. Mortenson" 2 => "S.A. Niccoli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Med" "fecha" => "1990" "volumen" => "88" "paginaInicial" => "396" "paginaFinal" => "404" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2183601" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bb0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute exacerbation in idiopathic pulmonary fibrosis: analysis of clinical and pathologic findings in three cases" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "Y. Kondoh" 1 => "H. Taniguchi" 2 => "Y. Kawabata" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1993" "volumen" => "103" "paginaInicial" => "1808" "paginaFinal" => "1812" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8404104" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bb0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "CT findings during phase of accelerated deterioration in patients with idiopathic pulmonary fibrosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "M. Akira" 1 => "H. Hamada" 2 => "M. Sakatani" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Roentgenol" "fecha" => "1997" "volumen" => "168" "paginaInicial" => "79" "paginaFinal" => "83" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bb0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute exacerbation of idiopathic pulmonary fibrosis: report of a series" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "V. Ambrosini" 1 => "A. Cancellieri" 2 => "M. Chilosi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "2003" "volumen" => "22" "paginaInicial" => "821" "paginaFinal" => "826" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14621091" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bb0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The clinical course of patients with idiopathic pulmonary fibrosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "F.J. Martinez" 1 => "S. Safrin" 2 => "D. Weycker" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med" "fecha" => "2005" "volumen" => "142" "paginaInicial" => "963" "paginaFinal" => "967" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15968010" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bb0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Double-blind placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "A. Azuma" 1 => "T. Nukwa" 2 => "E. Tsuboi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/rccm.200404-571OC" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2005" "volumen" => "171" "paginaInicial" => "1040" "paginaFinal" => "1047" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15665326" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bb0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute exacerbation of idiopathic pulmonary fibrosis: frequency and clinical features" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "D.S. Kim" 1 => "J.H. Park" 2 => "B.K. Park" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur Resp J" "fecha" => "2006" "volumen" => "27" "paginaInicial" => "143" "paginaFinal" => "150" ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bb0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchoalveolar lavage as a possible cause of acute exacerbation in idiopathic pulmonary fibrosis patients" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "N. Hiwatari" 1 => "S. Shimura" 2 => "T. Takishima" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Tohoku J Exp Med" "fecha" => "1994" "volumen" => "174" "paginaInicial" => "379" "paginaFinal" => "386" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7732520" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bb0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute exacerbation of idiopathic pulmonary fibrosis following surgical lung biopsy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "Y. Kondoh" 1 => "H. Taniguchi" 2 => "M. Kitaichi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.rmed.2006.02.002" "Revista" => array:6 [ "tituloSerie" => "Respir Med" "fecha" => "2006" "volumen" => "100" "paginaInicial" => "1753" "paginaFinal" => "1759" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16584880" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bb0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute exacerbation of interstitial fibrosis after pulmonary resection" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "M. Yüksel" 1 => "M.O. Özyurtkan" 2 => "K. Bostanci" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.athoracsur.2005.09.036" "Revista" => array:6 [ "tituloSerie" => "Ann Thorac Surg" "fecha" => "2006" "volumen" => "82" "paginaInicial" => "336" "paginaFinal" => "338" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16798250" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bb0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Histopathologic features and outcome of patients with acute exacerbation of idiopathic pulmonary fibrosis undergoing surgical lung biopsy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.G. Parambil" 1 => "J.L. Myers" 2 => "J.H. Ryu" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.128.5.3310" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2005" "volumen" => "128" "paginaInicial" => "3310" "paginaFinal" => "3315" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16304277" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bb0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute exacerbation of idiopathic pulmonary fibrosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R. Dallari" 1 => "M. Foglia" 2 => "M. Paci" 3 => "A. Cavazza" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur Respir J" "fecha" => "2004" "volumen" => "23" "paginaInicial" => "792" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15176701" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "pt" "url" => "/08732159/0000001500000002/v1_201509151524/S0873215915301331/v1_201509151524/pt/main.assets" "Apartado" => array:4 [ "identificador" => "43360" "tipo" => "SECCION" "pt" => array:2 [ "titulo" => "Casos Clínicos/Cases Reports" "idiomaDefecto" => true ] "idiomaDefecto" => "pt" ] "PDF" => "https://static.elsevier.es/multimedia/08732159/0000001500000002/v1_201509151524/S0873215915301331/v1_201509151524/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915301331?idApp=UINPBA00004E" ]
Article information
ISSN: 08732159Original language: Portuguese
The statistics are updated each day
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 12 | 16 |
| 2024 October | 48 | 45 | 93 |
| 2024 September | 28 | 48 | 76 |
| 2024 August | 46 | 68 | 114 |
| 2024 July | 41 | 60 | 101 |
| 2024 June | 40 | 47 | 87 |
| 2024 May | 41 | 53 | 94 |
| 2024 April | 35 | 54 | 89 |
| 2024 March | 30 | 54 | 84 |
| 2024 February | 35 | 54 | 89 |
| 2024 January | 26 | 40 | 66 |
| 2023 December | 23 | 49 | 72 |
| 2023 November | 22 | 63 | 85 |
| 2023 October | 17 | 79 | 96 |
| 2023 September | 22 | 76 | 98 |
| 2023 August | 16 | 68 | 84 |
| 2023 July | 33 | 102 | 135 |
| 2023 June | 30 | 39 | 69 |
| 2023 May | 28 | 72 | 100 |
| 2023 April | 29 | 66 | 95 |
| 2023 March | 38 | 106 | 144 |
| 2023 February | 26 | 66 | 92 |
| 2023 January | 37 | 47 | 84 |
| 2022 December | 25 | 52 | 77 |
| 2022 November | 41 | 73 | 114 |
| 2022 October | 49 | 68 | 117 |
| 2022 September | 27 | 96 | 123 |
| 2022 August | 46 | 91 | 137 |
| 2022 July | 35 | 65 | 100 |
| 2022 June | 28 | 62 | 90 |
| 2022 May | 52 | 75 | 127 |
| 2022 April | 33 | 65 | 98 |
| 2022 March | 26 | 34 | 60 |
| 2022 February | 52 | 40 | 92 |
| 2022 January | 46 | 56 | 102 |
| 2021 December | 35 | 46 | 81 |
| 2021 November | 28 | 38 | 66 |
| 2021 October | 32 | 57 | 89 |
| 2021 September | 31 | 45 | 76 |
| 2021 August | 42 | 30 | 72 |
| 2021 July | 44 | 28 | 72 |
| 2021 June | 43 | 31 | 74 |
| 2021 May | 68 | 40 | 108 |
| 2021 April | 119 | 76 | 195 |
| 2021 March | 70 | 14 | 84 |
| 2021 February | 81 | 17 | 98 |
| 2021 January | 46 | 22 | 68 |
| 2020 December | 26 | 17 | 43 |
| 2020 November | 72 | 24 | 96 |
| 2020 October | 40 | 22 | 62 |
| 2020 September | 67 | 24 | 91 |
| 2020 August | 62 | 33 | 95 |
| 2020 July | 88 | 22 | 110 |
| 2020 June | 77 | 28 | 105 |
| 2020 May | 92 | 36 | 128 |
| 2020 April | 89 | 21 | 110 |
| 2020 March | 58 | 24 | 82 |
| 2020 February | 50 | 48 | 98 |
| 2020 January | 47 | 27 | 74 |
| 2019 December | 52 | 29 | 81 |
| 2019 November | 67 | 40 | 107 |
| 2019 October | 51 | 28 | 79 |
| 2019 September | 51 | 52 | 103 |
| 2019 August | 62 | 48 | 110 |
| 2019 July | 50 | 29 | 79 |
| 2019 June | 53 | 50 | 103 |
| 2019 May | 55 | 92 | 147 |
| 2019 April | 51 | 62 | 113 |
| 2019 March | 98 | 55 | 153 |
| 2019 February | 67 | 45 | 112 |
| 2019 January | 66 | 52 | 118 |
| 2018 December | 41 | 31 | 72 |
| 2018 November | 16 | 2 | 18 |
| 2018 October | 5 | 8 | 13 |
| 2018 September | 30 | 10 | 40 |
| 2018 August | 71 | 31 | 102 |
| 2018 July | 59 | 26 | 85 |
| 2018 June | 74 | 19 | 93 |
| 2018 May | 69 | 21 | 90 |
| 2018 April | 88 | 28 | 116 |
| 2018 March | 63 | 29 | 92 |
| 2018 February | 37 | 9 | 46 |
| 2018 January | 55 | 15 | 70 |
| 2017 December | 57 | 16 | 73 |
| 2017 November | 51 | 20 | 71 |
| 2017 October | 44 | 18 | 62 |
| 2017 September | 32 | 12 | 44 |
| 2017 August | 27 | 14 | 41 |
| 2017 July | 21 | 5 | 26 |
| 2017 June | 33 | 10 | 43 |
| 2017 May | 38 | 8 | 46 |
| 2017 April | 16 | 3 | 19 |
| 2017 March | 22 | 3 | 25 |
| 2017 February | 12 | 3 | 15 |
| 2017 January | 14 | 2 | 16 |
| 2016 December | 14 | 6 | 20 |
| 2016 November | 8 | 3 | 11 |
| 2016 October | 8 | 10 | 18 |
| 2016 September | 3 | 1 | 4 |
| 2016 August | 4 | 3 | 7 |
| 2016 July | 4 | 4 | 8 |
| 2016 June | 1 | 7 | 8 |
| 2016 May | 0 | 2 | 2 |
| 2016 April | 1 | 2 | 3 |
| 2016 March | 4 | 1 | 5 |
| 2016 February | 1 | 8 | 9 |
| 2016 January | 5 | 2 | 7 |
| 2015 December | 7 | 2 | 9 |
| 2015 November | 5 | 2 | 7 |
| 2015 October | 3 | 3 | 6 |
Show all
