Artigo Original/Original Article
Evolução da mortalidade por cancro do pulmão em Portugal (1955-2005)
Trends in lung cancer mortality in Portugal (1955-2005)
Luís Alves1,2,3,
, Joana Bastos1,3, Nuno Lunet1,3
Corresponding author
lalves@med.up.pt
Correspondência/Correspondence to: Luís Alves Serviço de Higiene e Epidemiologia Faculdade de Medicina da Universidade do Porto Alameda Prof. Hernâni Monteiro 4200-319 Porto, Portugal, Telefone: +351225513652 Fax: +351225513653.
Correspondência/Correspondence to: Luís Alves Serviço de Higiene e Epidemiologia Faculdade de Medicina da Universidade do Porto Alameda Prof. Hernâni Monteiro 4200-319 Porto, Portugal, Telefone: +351225513652 Fax: +351225513653.
1 Serviço de Higiene e Epidemiologia, Faculdade de Medicina da Universidade do Porto, Portugal/Hygiene and Epidemiology Unit, Faculty of Medicine, Universidade do Porto, Portugal
2 Unidade de Saúde Familiar Santo André de Canidelo, Vila Nova de Gaia, Portugal/Santo André de Canidelo Family Health Unit, Vila Nova de Gaia, Portugal
3 Instituto de Saúde Publica da Universidade do Porto (ISPUP), Portugal/Institute of Public Health, Universidade do Porto(ISPUP), Portugal
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Contudo, até 1998 não se observava ainda um decréscimo da frequência deste cancro em Portugal.</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Objectivo:</span> Descrever a tendência secular da mortalidade por cancro do pulmão em Portugal.</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Métodos:</span> As taxas de mortalidade por cancro do pulmão (ICD10:C33-34) em Portugal, entre 1955 e 2005, por sexo e grupo etário (5 anos de amplitude), obtiveram-se através da Organização Mundial de Saúde e do Instituto Nacional de Estatística. Calcularam-se taxas de mortalidade padronizadas (método directo, população mundial), para os grupos etários 35-74/35-44/45-54/55-64/65-74 anos. Realizou-se uma regressão <span class="elsevierStyleItalic">joinpoint</span> para calcular a variação anual percentual (VA%) da mortalidade e identificar eventuais pontos de inflexão.</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Resultados:</span> Entre 1955 e 2005, em homens dos 35 aos 74 anos, observou-se uma estabilização da mortalidade por cancro do pulmão, variando 3,77%/ano (intervalo de confiança a 95% [IC95%]: 3,53; 4,01) entre 1955 e 1986 e -0,15%/ano (IC95%: -0,99; 0,69) entre 1996 e 2005. Observaram-se estimativas pontuais da VA% negativas (não significativamente inferiores a zero) nas tendências mais recentes de todos os grupos etários, excepto no grupo 45-54 anos, onde apenas se verificou uma desaceleração da VA% desde 1981. Em mulheres entre 35 e 74 anos, a mortalidade aumentou 1,60%/ano (IC95%: 1,40; 1,77) entre 1955 e 2005.</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclusão:</span> Observou-se uma estabilização das taxas de mortalidade por cancro do pulmão nos homens, enquanto nas mulheres esta aumentou de forma constante. Estes resultados colocam Portugal no final do terceiro estádio da epidemia tabágica.</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2009; XV (4): 575-587</span></p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0035" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Introduction:</span> While the rate of smoking and lung cancer mortality has been decreasing in western Europe, there was no decline in lung cancer mortality in Portugal until 1998.</p><p id="sp0040" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Aim:</span> To describe lung cancer mortality trends in Portugal.</p><p id="sp0045" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Methods:</span> Lung cancer mortality rates (International Disease Classification 10: C33-34) in Portugal 1955-2005 by gender and 5-year age groupings were provided by the World Health Organization and the National Institute of Statistics. Standard mortality rates (direct method, world population) were calculated for the 35-74, 35-44, 45-54, 55-64 and 65-74 year-old age groups. Joinpoint regression was used to calculate the annual percent change (APC) in mortality and to identify any inflection points.</p><p id="sp0050" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Results:</span> Between 1955 and 2005 we observed a stabilisation in lung cancer mortality in men aged 35-74 years old, varying 3.77%/year (95% confidence interval [95%CI]: 3.53-4.01) in 1955-1986 and -0.15%/year (95%CI: -0.99-0.69) in 1996-2005. We observed negative APC point estimates (with none significantly below zero) in the most recent trends except for the 45-54 age group, where we only noted an APC deceleration since 1981. The mortality increased 1.60%/year (95%CI: 1.40-1.77) in women aged 35-74 years old 1955-2005.</p><p id="sp0055" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclusion:</span> In the last two decades we observed a lung cancer mortality stabilisation in males, whereas mortality in females increased continuously. These results place Portugal at the end of the third stage of the smoking epidemic.</p><p id="sp0060" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2009; XV (4): 575-587</span></p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0025">Bibliografia/Bibliography</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:27 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." 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Article information
ISSN: 08732159Original language: Portuguese
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