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Artigo de Revisão/Review Article
Doença pulmonar obstrutiva crónica – Uma revisão
Chronic obstructive pulmonary disease – A review
Artur Laizo1,
Corresponding author
alaizo@oi.com.br

Universidade Presidente Antônio Carlos – Campus VI – Juiz de Fora
1 Mestre em Cirurgia Geral pela UFMG, intensivista, coordenador do Grupo de Estudos Sobre DPOC (GEDPOC), professor nas disciplinas Primeiros Socorros, Farmacologia e Fundamentos de Pneumologia, dos cursos da área de saúde da Universidade Presidente Antônio Carlos – UNIPAC – campus VI, Juiz de Fora – MG.
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        "titulo" => "Resumo"
        "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">A DPOC &#233; uma doen&#231;a preven&#237;vel e trat&#225;vel ocasionada pela exposi&#231;&#227;o ao tabagismo e gases t&#243;xicos&#46; A sua caracter&#237;stica &#233; a obstru&#231;&#227;o progressiva ao fluxo a&#233;reo de irrevers&#237;vel depois de ocorrerem as les&#245;es no par&#234;nquima&#46; O objectivo do trabalho &#233; uma revis&#227;o sistem&#225;tica da doen&#231;a e da forma de tratamento&#46; <span class="elsevierStyleBold">Discuss&#227;o&#58;</span> o tabagismo &#233; a maior causa de DPOC e leva a n&#227;o s&#243; uma diminui&#231;&#227;o da oxigena&#231;&#227;o por hiperinsufla&#231;&#227;o pulmonar com redu&#231;&#227;o do fluxo a&#233;reo como a um processo inflamat&#243;rio sist&#233;mico&#44; reduzindo a resist&#234;ncia &#224; fadiga da musculatura esquel&#233;tica produzindo hipoxemia&#44; diminui&#231;&#227;o do fluxo sangu&#237;neo perif&#233;rico&#44; levando inclusive a abortos espont&#226;neos e partos prematuros&#46; Marcadores inflamat&#243;rios como as interleucinas e o TNF-alfa mant&#234;m o quadro sist&#233;mico&#46; A cessa&#231;&#227;o do tabagismo melhora a hipoxemia&#44; a intoler&#226;ncia ao exerc&#237;cio&#44; por&#233;m n&#227;o recupera o tecido lesado&#46; A DPOC &#233; uma doen&#231;a grave que pode ser evitada se houver uma consciencializa&#231;&#227;o maior da popula&#231;&#227;o a respeito dos malef&#237;cios do cigarro&#46;</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2009&#59; XV &#40;6&#41;&#58; 1157-1166</span></p></span>"
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Article information
ISSN: 08732159
Original language: Portuguese
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