Stress oxidativo na lesão pulmonar neonatal

array:24 ["pii" => "S087321591530221X" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)30221-X" "estado" => "S350" "fechaPublicacion" => "2008-01-01" "aid" => "1" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "copyrightAnyo" => "2008" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "rev" "cita" => "Rev Port Pneumol. 2008;14:113-26" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2394 "formatos" => array:3 [ "EPUB" => 215 "HTML" => 1399 "PDF" => 780 ] ] "itemSiguiente" => array:19 [ "pii" => "S0873215915302221" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)30222-1" "estado" => "S350" "fechaPublicacion" => "2008-01-01" "aid" => "2" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "rev" "cita" => "Rev Port Pneumol. 2008;14:127-40" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2549 "formatos" => array:3 [ "EPUB" => 231 "HTML" => 1686 "PDF" => 632 ] ] "pt" => array:11 [ "idiomaDefecto" => true "cabecera" => "Artigo de Revisão/Revision Article" "titulo" => "Sarcoidose extratorácica" "tienePdf" => "pt" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "pt" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "127" "paginaFinal" => "140" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Extra-thoracic sarcoidosis" ] ] "contieneResumen" => array:2 [ "pt" => true "en" => true ] "contienePdf" => array:1 [ "pt" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Filipa Costa, Ana Arrobas" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Filipa" "apellidos" => "Costa" ] 1 => array:2 [ "nombre" => "Ana" "apellidos" => "Arrobas" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915302221?idApp=UINPBA00004E" "url" => "/08732159/0000001400000001/v1_201509151510/S0873215915302221/v1_201509151510/pt/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S0873215915302208" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)30220-8" "estado" => "S350" "fechaPublicacion" => "2008-01-01" "aid" => "12" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "rev" "cita" => "Rev Port Pneumol. 2008;14:89-112" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2590 "formatos" => array:3 [ "EPUB" => 253 "HTML" => 1616 "PDF" => 721 ] ] "pt" => array:11 [ "idiomaDefecto" => true "cabecera" => "Artigo de Revisão/Revision Article" "titulo" => "Fibrose quística: Revisão" "tienePdf" => "pt" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "pt" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "89" "paginaFinal" => "112" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Cystic fibrosis: Review" ] ] "contieneResumen" => array:2 [ "pt" => true "en" => true ] "contienePdf" => array:1 [ "pt" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "C. Damas, A. Amorim, I. Gomes" "autores" => array:3 [ 0 => array:2 [ "nombre" => "C." "apellidos" => "Damas" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Amorim" ] 2 => array:2 [ "nombre" => "I." "apellidos" => "Gomes" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915302208?idApp=UINPBA00004E" "url" => "/08732159/0000001400000001/v1_201509151510/S0873215915302208/v1_201509151510/pt/main.assets" ] "pt" => array:15 [ "idiomaDefecto" => true "cabecera" => "Artigo de Revisão/Revision Article" "titulo" => "Stress oxidativo na lesão pulmonar neonatal" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "113" "paginaFinal" => "126" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Gustavo Rocha" "autores" => array:1 [ 0 => array:4 [ "nombre" => "Gustavo" "apellidos" => "Rocha" "email" => array:1 [ 0 => "gusrocha@oninet.pt" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "1" "identificador" => "af0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cr0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Assistente Hospitalar, Serviço de Neonatologia. Unidade Autónoma de Gestão da Mulher e da Criança, Hospital de São João, Porto. Faculdade de Medicina da Universidade do Porto" "etiqueta" => "1" "identificador" => "af0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cr0005" "etiqueta" => "*" "correspondencia" => "Correspondência: Gustavo Rocha, Serviço de Neonatologia, Unidade Autónoma de Gestão da Mulher e da Criança, Hospital de São João – Piso 2, Alameda Prof. Hernâni Monteiro, 4202 – 451 Porto, Telefone: 22 551 21 00 ext: 1949, Fax: 22 551 22 73 / 22 502 57 66." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Oxidative stress in the neonatal lung disease" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-06-01" "fechaAceptado" => "2007-07-31" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec570299" "palabras" => array:4 [ 0 => "Displasia broncopulmonar" 1 => "defesa antioxidante" 2 => "recém-nascido de pré-termo" 3 => "stress oxidativo" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec570298" "palabras" => array:4 [ 0 => "Bronchopulmonary dysplasia" 1 => "antioxidant defense" 2 => "preterm infant" 3 => "oxidative stress" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "O stress oxidativo é um dos factores de risco para o desenvolvimento de displasia broncopulmonar no recém-nascido de pré-termo. Este apresenta deficiente defesa antioxidante. Por outro lado, o stress oxidativo também tem papel no crescimento e desenvolvimento celular. A relação entre stress oxidativo e crescimento celular necessita de ser melhor conhecida antes da introdução de terapêuticas antioxidantes. Várias terapêuticas antioxidantes têm sido tentadas, até ao momento sem êxito. Neste artigo é feita uma revisão da evidência do papel dos radicais livres de oxigénio na displasia broncopulmonar.Rev Port Pneumol 2008; XIV (1): 113-126" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "Oxidative stress is a risk factor for bronchopulmonary dysplasia in the preterm newborn. Antioxidant defense is impaired in the preterm newborn. Oxidative stress is also involved in cell growth and development. The relationship between oxidative stress and cell growth needs to be understood before antioxidant therapy can be routinely introduced. Several antioxidant therapies have been unsuccessfully tried until now. This review highlights the importance of oxygen free radicals in the pathogenesis of bronchopulmonary dysplasia.Rev Port Pneumol 2008; XIV (1): 113-126" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:84 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intensive oxygen therapy as a possible cause of retrolental fibroplasia: a clinical approach" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "K. 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Artigo de Revisão/Revision Article

Stress oxidativo na lesão pulmonar neonatal

Oxidative stress in the neonatal lung disease

Gustavo Rocha1,

Corresponding author

gusrocha@oninet.pt

Correspondência: Gustavo Rocha, Serviço de Neonatologia, Unidade Autónoma de Gestão da Mulher e da Criança, Hospital de São João – Piso 2, Alameda Prof. Hernâni Monteiro, 4202 – 451 Porto, Telefone: 22 551 21 00 ext: 1949, Fax: 22 551 22 73 / 22 502 57 66.

1 Assistente Hospitalar, Serviço de Neonatologia. Unidade Autónoma de Gestão da Mulher e da Criança, Hospital de São João, Porto. Faculdade de Medicina da Universidade do Porto

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Article information

ISSN: 08732159
Original language: Portuguese

DOI:10.1016/S0873-2159(15)30221-X

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Year/Month	Html	Pdf	Total

2024 November	9	6	15
2024 October	36	41	77
2024 September	26	24	50
2024 August	51	42	93
2024 July	45	24	69
2024 June	22	23	45
2024 May	29	25	54
2024 April	29	22	51
2024 March	34	31	65
2024 February	31	25	56
2024 January	25	20	45
2023 December	18	15	33
2023 November	26	24	50
2023 October	20	29	49
2023 September	20	23	43
2023 August	20	19	39
2023 July	21	30	51
2023 June	27	11	38
2023 May	20	22	42
2023 April	16	18	34
2023 March	28	22	50
2023 February	29	27	56
2023 January	30	22	52
2022 December	33	29	62
2022 November	35	31	66
2022 October	35	20	55
2022 September	24	29	53
2022 August	36	38	74
2022 July	28	33	61
2022 June	19	37	56
2022 May	37	36	73
2022 April	26	21	47
2022 March	26	34	60
2022 February	26	22	48
2022 January	19	39	58
2021 December	25	39	64
2021 November	26	26	52
2021 October	21	31	52
2021 September	24	20	44
2021 August	14	20	34
2021 July	19	23	42
2021 June	18	21	39
2021 May	20	25	45
2021 April	36	31	67
2021 March	38	12	50
2021 February	27	18	45
2021 January	43	6	49
2020 December	10	6	16
2020 November	30	21	51
2020 October	26	10	36
2020 September	33	30	63
2020 August	42	20	62
2020 July	69	17	86
2020 June	51	17	68
2020 May	73	22	95
2020 April	53	10	63
2020 March	55	15	70
2020 February	53	21	74
2020 January	50	21	71
2019 December	49	18	67
2019 November	46	16	62
2019 October	56	21	77
2019 September	49	14	63
2019 August	71	22	93
2019 July	40	18	58
2019 June	58	29	87
2019 May	49	36	85
2019 April	42	23	65
2019 March	50	17	67
2019 February	60	10	70
2019 January	50	17	67
2018 December	36	6	42
2018 November	5	7	12
2018 October	4	1	5
2018 September	13	7	20
2018 August	35	38	73
2018 July	30	25	55
2018 June	42	27	69
2018 May	56	27	83
2018 April	31	36	67
2018 March	51	32	83
2018 February	22	9	31
2018 January	16	19	35
2017 December	39	12	51
2017 November	21	21	42
2017 October	35	20	55
2017 September	18	13	31
2017 August	27	28	55
2017 July	27	12	39
2017 June	21	12	33
2017 May	48	15	63
2017 April	11	7	18
2017 March	16	43	59
2017 February	13	6	19
2017 January	15	11	26
2016 December	15	6	21
2016 November	9	4	13
2016 October	9	14	23
2016 September	2	4	6
2016 August	5	4	9
2016 July	4	3	7
2016 May	10	4	14
2016 April	3	4	7
2016 March	1	4	5
2016 February	5	8	13
2016 January	3	7	10
2015 December	8	1	9
2015 November	1	3	4
2015 October	3	3	6

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