Artigo Original/Original Article
Alterações ecocardiográficas em doentes asmáticos
Echocardiograph alterations in asthma patients
André Luís Mancini1, Sonia Regina da Silva Carvalho2, Maria do Carmo Valente de Crasto3, Ricardo Marques Dias4,
Corresponding author
dias.ricardomarques@gmail.com
Endereço correspondência / Corresponding author: Ricardo Marques Dias, Rua Barão da Torre 388/104, Ipanema, Rio de Janeiro, Brasil. CEP 22411.000. Tel: 55 21 22472431.
Endereço correspondência / Corresponding author: Ricardo Marques Dias, Rua Barão da Torre 388/104, Ipanema, Rio de Janeiro, Brasil. CEP 22411.000. Tel: 55 21 22472431.
1 Médico formado pela Universidade Federal do Estado do Rio de Janeiro – UNIRIO. Monitor da disciplina de Iniciação Científica 2 / Doctor trained at Universidade Federal do Estado do Rio de Janeiro – UNIRIO. Teaching Assistant, Iniciação Científica 2
2 Prof. Assistente da Universidade Federal do Estado do Rio de Janeiro – UNIRIO. Mestre em medicina / Assistant Professor, Universidade Federal do Estado do Rio de Janeiro – UNIRIO. MSc, Medicine
3 Prof. Adjunto da Universidade Federal do Estado do Rio de Janeiro – UNIRIO. Doutor em medicina / Adjunct Professor, Universidade Federal do Estado do Rio de Janeiro – UNIRIO. PhD, Medicine
4 Universidade Federal do Estado do Rio de Janeiro – UNIRIO. Doutor em medicina / Professor at Universidade Federal do Estado do Rio de Janeiro – UNIRIO. PhD, Medicine
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Tel: 55 21 22472431." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Echocardiograph alterations in asthma patients" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-02-22" "fechaAceptado" => "2008-01-22" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec570487" "palabras" => array:3 [ 0 => "Asma" 1 => "ecocardiograma" 2 => "hipertensão arterial pulmonar" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec570486" "palabras" => array:3 [ 0 => "Asthma" 1 => "electrocardiogram" 2 => "echocardiogram" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Introdução:</span> A asma é uma doença inflamatória cró-nica cuja prevalência vem aumentando nos últimos 20 anos. Demanda grande utilização de recursos, principalmente no grupo grave. Neste, há consumo crónico de corticóides inalatórios e de β2-agonistas, que podem produzir uma série de problemas. O objectivo deste trabalho é o de rastrear as alterações electro e ecocardiográficas e relacioná-las ao grau da asma.</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Metodologia:</span> Selecionámos 87 doentes do ambula-tório de asma do HUGG, que, por rotina, possuem uma espirografia, um eletrocardiograma (ECG) e um ecocardiograma (ECO) feitos com um intervalo máximo de um mês. As alterações ecocardiográficas encontradas foram relacionadas com o grau da asma. Foram usadas estatísticas não paramétricas para essas comparações.</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Resultados:</span> Encontrámos diferenças significativas (p<span class="elsevierStyleHsp" style=""></span>≤<span class="elsevierStyleHsp" style=""></span>0,05) quanto à idade, tempo de asma e saturação da hemoglobina (SaO<span class="elsevierStyleInf">2</span>) entre os grupos leve e grave. Na amostra, foi identificada alta prevalência de insuficiência tricúspide (41,4%).</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclusões:</span> O ECO identificou uma série de anor-malidades, dependentes ou não da gravidade da asma. O ECO pode identificar a hipertensão arterial pulmonar, pelo cálculo da pressão média da artéria pulmonar.</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2008; XIV (3): 363-377</span></p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Introduction:</span> Asthma is a chronic inflammatory disease which has increased during the last 20 years, putting a strain on medical resources, particularly severe forms of the disease. Treatment in such cases is inhaled corticosteroids and beta agonist drugs that can produce a range of side effects. The aim of this study is to identify echocardiograph abnormalities and correlate them with severity of disease.</p><p id="sp0035" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Methodology:</span> Eight-seven outpatients were selected at the asthma unit of the Gaffrée Guinle University Hospital (HUGG). Each patient underwent spirometry, electrocardiogram (ECG) and echocardiogram (ECO) during the trial within a month maximum. Echocardiograph abnormalities found related to degree of asthma. Statistical analysis was made by non-parametric tests.</p><p id="sp0040" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Results:</span> We found significant differences (p<span class="elsevierStyleHsp" style=""></span>≤<span class="elsevierStyleHsp" style=""></span>0.05) for age, disease duration and haemoglobin saturation (SaO<span class="elsevierStyleInf">2</span>) between the moderate and severe groups. In the sample a high prevalence of tricuspid insufficiency (41.4%) was identified.</p><p id="sp0045" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclusions:</span> ECO identified a series of abnormalities that were not always dependent on severity of disease. ECO can identify pulmonary hypertension through calculation of mean pressure of the pulmonary artery.</p><p id="sp0050" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2008; XIV (3): 363-377</span></p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0025">Bibliografia</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:23 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "titulo" => "III Consenso Brasileiro no Manejo da Asma" ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Jornal de Pneumologia" "fecha" => "2002" "volumen" => "28" "numero" => "Supl 1" "paginaInicial" => "S1" "paginaFinal" => "S28" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bb0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intergenerational 20 year trends in the prevalence of asthma and hay fever in adults: the Midspan family study surveys of parents and offspring" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M.N. Upton" 1 => "A. McConnachie" 2 => "C. Mcsharry" 3 => "C.L. Hart" 4 => "G.D. Smith" 5 => "C.R. Gillis" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "British Medical Journal" "fecha" => "2000" "volumen" => "321" "paginaInicial" => "88" "paginaFinal" => "92" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10884260" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bb0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Global Initiative for Asthma (GINA) – <a href="http://www.ginas-thma.com">www.ginas-thma.com</a>, acessado em 14/03/2005 às 19:00." ] ] ] 3 => array:3 [ "identificador" => "bb0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Serum potassium levels, CPK-MB and ECG in children suffering asthma treated with beclomethasone or beclomethasone-salmeterol" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "B.E. Del Río-Navarro" 1 => "J.J. Sienra-Monge" 2 => "M. Álvarez-Amador" 3 => "N. Reyes-Ruiz" 4 => "A. Arevalo-Salas" 5 => "A. Berber" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Allergol et Immunopathol" "fecha" => "2001" "volumen" => "29" "numero" => "1" "paginaInicial" => "16" "paginaFinal" => "21" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bb0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Interaction between corticosteroid and beta-agonist drugs" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "D.R. Taylor" 1 => "G.T. Wilkins" 2 => "G.P. Herbison" 3 => "E.M. Flannery" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Biochemical and cardiovascular effects in normal subjects. Chest" "fecha" => "1992" "volumen" => "102" "numero" => "2" "paginaInicial" => "519" "paginaFinal" => "524" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1353717" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bb0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ozyurek H" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.P. Uyan" 1 => "C. Uyan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Assessment of right diastolic filling parameters by Doppler echocardiography Pediatr Int [SI]" "fecha" => "2003" "volumen" => "45" "numero" => "3" "paginaInicial" => "7" "paginaFinal" => "263" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bb0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Left ventricular diastolic dysfunction in patients with bronchial asthma with long-term oral beta2-adrenoceptor agonists" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "O. Hirono" 1 => "I. Kubota" 2 => "O. Minamihaba" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am Heart J [SI]" "fecha" => "2001" "volumen" => "142" "numero" => "6" "paginaInicial" => "E11" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bb0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Non invasive assessment of cardiac function in pacients with bronchial asthma (BA) or chronic obstructive pulmonary disease (COPD)" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "G.F. Bagnato" 1 => "A. Mileto" 2 => "S. Gulli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Allergol Imminopathol (Madr)" "fecha" => "1999" "volumen" => "27" "numero" => "1" "paginaInicial" => "5" "paginaFinal" => "10" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bb0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of salbutamol on left ventricular function and selected biochemical parameters in patients with bronchial asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "R. Chazan" 1 => "M. Jakubowska-Najnigier" 2 => "D. Liszewska-Pfejfer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pol Arch Med Wewn [SI]" "fecha" => "1994" "volumen" => "92" "numero" => "4" "paginaInicial" => "299" "paginaFinal" => "305" ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bb0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of acute bronchospasm on pulmonary artery pressure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R. Sarac" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lijec Vjesn [SI]" "fecha" => "1991" "volumen" => "113" "numero" => "11–12" "paginaInicial" => "3" "paginaFinal" => "390" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bb0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary pulmonary hypertension: insights into pathogenesis from epidemiology" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "N. Galie" 1 => "A. Manes" 2 => "L. Uguccioni" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Chest [SI]" "fecha" => "1998" "volumen" => "114" "paginaInicial" => "94" "paginaFinal" => "184" ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bb0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hypokalemic and ECG Sequelae of Combined Beta-Agonist/Diuretic Therapy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:1 [ 0 => "B.J. Lipworth" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1990" "volumen" => "98" "paginaInicial" => "5" "paginaFinal" => "811" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2361412" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bb0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Changes in the normal maximal expiratory flow volume curve with growth and aging" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "R.J. Knudson" 1 => "M.D. Lebowitz" 2 => "C.J. Holberg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1983" "volumen" => "127" "paginaInicial" => "34" "paginaFinal" => "725" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bb0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Standardization of spirometry: 1994 Update" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "American Thoracic Society" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1995" "volumen" => "152" "paginaInicial" => "36" "paginaFinal" => "1107" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bb0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidemiology standardization project: recommended standardization procedure for pulmonary function testing" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "American Thoracic Society" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/arrd.1978.118.1.55" "Revista" => array:7 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1978" "volumen" => "118" "numero" => "Suppl 2" "paginaInicial" => "55" "paginaFinal" => "88" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/677558" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bb0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L.E. Febiger" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "edicion" => "5" "titulo" => "Echocardiography Harvey" "fecha" => "1994" "editorial" => "EUA" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bb0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "titulo" => "Classificação e avaliação diagnóstica da hipertensão pulmonar" ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Brás Pneumol" "fecha" => "2005" "volumen" => "31" "numero" => "Supl 2" "paginaInicial" => "S1" "paginaFinal" => "S8" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bb0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.K. Oh" 1 => "J.B. Seward" 2 => "A.J. Tajik" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:2 [ "titulo" => "Ecocardiografia – Clínica Mayo" "fecha" => "1997" ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bb0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Microsoft® Office Excel 2003 versão 11.6560.6568 SP2. Microsoft Office Professional Edição; USA, 2003." ] ] ] 19 => array:3 [ "identificador" => "bb0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "GraphPad Instat versão 3.01 para Windows 95, Copyright 1992-1998. GraphPad Software Inc, San Diego California USA, <a href="http://www.graphpad.com">www.graphpad.com</a>." ] ] ] 20 => array:3 [ "identificador" => "bb0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alterações eletrocardiográficas em pacientes asmáticos" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "A.L. Mancini" 1 => "S.R.S. Carvalho" 2 => "M.C.V. Crasto" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pulmão RJ" "fecha" => "2006" "volumen" => "15" "numero" => "2" "paginaInicial" => "4" "paginaFinal" => "70" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bb0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Medicina Interna" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "Harrison" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:6 [ "titulo" => "Cap" "paginaInicial" => "45" "paginaFinal" => "1539" "edicion" => "15" "serieVolumen" => "II" "serieFecha" => "2002" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bb0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Goodman e Gilman. As bases farmacológicas da terapêutica. 28:551-68 – 10.ª Ed. – Ed. 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Article information
ISSN: 08732159Original language: Portuguese
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