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Avaliação dos resultados nos ensaios clínicos na DPOC: Da função pulmonar aos marcadores biológicos
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Anakawa" "autores" => array:1 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Anakawa" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915302658?idApp=UINPBA00004E" "url" => "/08732159/0000001400000004/v1_201509151547/S0873215915302658/v1_201509151547/pt/main.assets" ] "pt" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">As Nossas Leituras</span>" "titulo" => "Avaliação dos resultados nos ensaios clínicos na DPOC: Da função pulmonar aos marcadores biológicos" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "579" "paginaFinal" => "583" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "M. Cazzola, W. MacNee, F.J. Martinez, K.F. Rabe" "autores" => array:4 [ 0 => array:3 [ "nombre" => "M." "apellidos" => "Cazzola" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "af0005" ] ] ] 1 => array:3 [ "nombre" => "W." "apellidos" => "MacNee" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "af0005" ] ] ] 2 => array:3 [ "nombre" => "F.J." "apellidos" => "Martinez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "af0005" ] ] ] 3 => array:3 [ "nombre" => "K.F." "apellidos" => "Rabe" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "af0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "On behalf of the ATS/ERS TASK Force on outcomes of COPD." "etiqueta" => "1" "identificador" => "af0005" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "tieneResumen" => true "resumen" => array:1 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">As sociedades científicas respiratórias europeia e americana (ERS e ATS) constituíram um grupo de trabalho sobre a “Avaliação dos resultados nos ensaios clínicos na DPOC: da função pulmonar aos marcadores biológicos” para informar a comunidade de investigadores em DPOC sobre o possível uso e limitações dos resultados obtidos e marcadores usados actualmente na avaliação do impacto da terapêutica farmacológica. Com base na revisão da literatura, este documento aborda diferentes secções que avaliam marcadores e resultados específicos: função pulmonar; resultados centrados no doente; exacerbações; nortalidade; impacto social e económico; exames de imagem; marcadores não pulmonares; mínima diferença clinicamente significativa; marcadores biológicos.</p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0010">Bibliografia</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." 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ISSN: 08732159Original language: Portuguese
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