Artigo de Revisão / Revision Article
O aparelho respiratório na doença vibroacústica: 25 anos de investigação
Respiratory pathology in vibroacoustic disease: 25 years of research
Read
4987
Timeswas read the article
1942
Total PDF
3045
Total HTML
Share statistics
array:23 [ "pii" => "S087321591530341X" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)30341-X" "estado" => "S350" "fechaPublicacion" => "2007-01-01" "aid" => "2" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "copyrightAnyo" => "2007" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "rev" "cita" => "Rev Port Pneumol. 2007;13:129-35" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2137 "formatos" => array:3 [ "EPUB" => 245 "HTML" => 1243 "PDF" => 649 ] ] "itemAnterior" => array:19 [ "pii" => "S0873215915303408" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)30340-8" "estado" => "S350" "fechaPublicacion" => "2007-01-01" "aid" => "1" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "rev" "cita" => "Rev Port Pneumol. 2007;13:101-28" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2261 "formatos" => array:3 [ "EPUB" => 199 "HTML" => 1364 "PDF" => 698 ] ] "pt" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Artigo de Revisão / Revision Article</span>" "titulo" => "Treino de exercício na doença pulmonar crónica" "tienePdf" => "pt" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "pt" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "101" "paginaFinal" => "128" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Exercise training in chronic pulmonary disease" ] ] "contieneResumen" => array:2 [ "pt" => true "en" => true ] "contienePdf" => array:1 [ "pt" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Paula Pamplona, Luísa Morais" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Paula" "apellidos" => "Pamplona" ] 1 => array:2 [ "nombre" => "Luísa" "apellidos" => "Morais" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915303408?idApp=UINPBA00004E" "url" => "/08732159/0000001300000001/v1_201509071333/S0873215915303408/v1_201509071333/pt/main.assets" ] "pt" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Artigo de Revisão / Revision Article</span>" "titulo" => "O aparelho respiratório na doença vibroacústica: 25 anos de investigação" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "129" "paginaFinal" => "135" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "Nuno A.A. Castelo Branco, José Reis Ferreira, Mariana Alves-Pereira" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Nuno A.A." "apellidos" => "Castelo Branco" "email" => array:1 [ 0 => "vibroacoustic.disease@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "af0005" ] ] ] 1 => array:3 [ "nombre" => "José Reis" "apellidos" => "Ferreira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "af0010" ] ] ] 2 => array:3 [ "nombre" => "Mariana" "apellidos" => "Alves-Pereira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "af0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Médico Anatomopatologista, presidente do Conselho Científico, Centro da Performance Humana, Alverca" "etiqueta" => "1" "identificador" => "af0005" ] 1 => array:3 [ "entidad" => "Médico Pneumologista, Unidade de Estudo Funcional Respiratório, Hospital da Força Aérea, Lisboa" "etiqueta" => "2" "identificador" => "af0010" ] 2 => array:3 [ "entidad" => "Engenheira Biomédica, ERISA – Universidade Lusófona" "etiqueta" => "3" "identificador" => "af0015" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Respiratory pathology in vibroacoustic disease: 25 years of research" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-02-28" "fechaAceptado" => "2006-11-10" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec567920" "palabras" => array:7 [ 0 => "Ruído de baixa frequência" 1 => "infra-sons" 2 => "fibrose" 3 => "derrame pleural" 4 => "broncoscopia" 5 => "cancro do pulmão" 6 => "sensibilidade ao CO<span class="elsevierStyleInf">2</span>" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec567921" "palabras" => array:7 [ 0 => "Low frequency noise" 1 => "infrasound" 2 => "fibrosis" 3 => "pleural effusion" 4 => "bronchoscopy" 5 => "lung cancer" 6 => "respiratory drive" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Enquadramento:</span> A patologia respiratória induzida pela exposição a ruído de baixa frequência (RBF, ≤<span class="elsevierStyleHsp" style=""></span>500<span class="elsevierStyleHsp" style=""></span>Hz, incluindo os infra-sons) não constitui novidade dado que, desde 1960, no âmbito dos programas espaciais dos EUA e da União Soviética, diversos autores divulgaram a sua existência. No contexto da doença vibroacústica (VAD – <span class="elsevierStyleItalic">vibroacoustic disease</span>), uma patologia sistémica causada pela exposição excessiva a RBF, as lesões respiratórias apresentam características próprias. Inicialmente, esta patologia respiratória não foi tida como uma consequência da exposição ao ruído; no entanto, hoje, o RBF é considerado um agente muito importante de doença respiratória. O objectivo deste trabalho é sistematizar e actualizar todos os dados sobre a patologia respiratória observada na VAD. <span class="elsevierStyleBold">Métodos:</span> Ao longo dos últimos 25 anos, reco-lheu-se informação, de modo continuado, de indivíduos e modelos animais expostos a RBF. Todos estes dados são aqui compilados. <span class="elsevierStyleBold">Resultados:</span> Em indivíduos expostos a ruído no trabalho, as queixas brônquicas aparecem nos primeiros 4 anos de actividade e, nesta fase, reduzem ou desaparecem quando de férias ou removidos do seu local de trabalho por outros motivos. Com a exposição prolongada, poderão surgir situações mais graves, como derrames pleurais, insuficiência respiratória, fibrose pulmonar e carcinomas do aparelho respiratório. Não existe correlação com hábitos tabágicos. Em modelos animais expostos a RBF, apresentavam-se alterações morfológicas da pleura e perda da capacidade fagocítica das células mesoteliais (explicando os derrames pleurais observados). Foram observadas lesões de fibrose e neovascularização ao longo de todo o aparelho respiratório dos animais expostos. Também se identificaram lesões pré-malignas, metaplasia e displasia. <span class="elsevierStyleBold">Conclusões:</span> O RBF é um agente de doença e tem como alvo preferencial o aparelho respiratório. A patologia respiratória associada à VAD necessita, ainda, de muito estudo para que uma maior compreenção possa ser alcançada e intervenções farmacológicas possam ser pensadas.</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2007; XIII (1): 129-135</span></p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Background:</span> Respiratory pathology induced by low frequency noise (LFN, <<span class="elsevierStyleHsp" style=""></span>500<span class="elsevierStyleHsp" style=""></span>Hz, including infrasound) is not a novel subject given that in the 1960’s, within the context of U.S. and U.S.S.R. Space Programs, other authors have already reported its existence. Within the scope of vibroacoustic disease (VAD), a whole-body pathology caused by excessive exposure to LFN, respiratory pathology takes on specific features. Initially, respiratory pathology was not considered a consequence of LFN exposure; but today, LFN can be regarded as a major agent of disease that targets the respiratory system. The goal of this report is to put forth what is known to date on the clinical signs of respiratory pathology seen in VAD patients. <span class="elsevierStyleBold">Methods:</span> Data from the past 25 years of research will be taken together and presented. <span class="elsevierStyleBold">Results:</span> In persons exposed to LFN on the job, respiratory complaints appear after the first 4 years of professional activity. At this stage, they disappear during vacation periods or when the person is removed form his /her workstation for other reasons. With long-term exposure, more serious situations can arise, such as, atypical pleural effusion, respiratory insufficiency, fibrosis and tumours. There is no correlation with smoking habits. In LFN-exposed animal models, morphological changes of the pleura, and loss of the phagocytic ability of pleural mesothelial cells (explaining the atypical pleural effusions). Fibrotic lesions and neo-vascularization were observed along the entire respiratory tract. Fibrosis lesions and neovascularisation were observed throughout the respiratory tract of the animals seen. Pre-ma-lignant lesions, metaplasia e displasia, were also identified. <span class="elsevierStyleBold">Discussion:</span> LFN is an agent of disease and the respiratory tract is one of its preferential targets. The respiratory pathology associated with VAD needs further in-depth studies in order to achieve a greater understanding, and develop methods of pharmacological intervention.</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2007; XIII (1): 129-135</span></p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0025">Bibliography</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:27 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of low-frequency and infrasonic noise on man" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "G.C. Mohr" 1 => "J.N. Cole" 2 => "E. Guild" 3 => "H.E. Von Gierke" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Aerospace Med" "fecha" => "1965" "volumen" => "36" "paginaInicial" => "817" "paginaFinal" => "824" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14332329" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bb0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Biological action of intense wide-band noise on animals" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:4 [ 0 => "V.I. Ponomarkov" 1 => "Tysik Ayu" 2 => "V.I. Kudryavtseva" 3 => "A.S. Barer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Problems of Space Biology NASA TT F-529" "fecha" => "1969" "volumen" => "7" "paginaInicial" => "307" "paginaFinal" => "309" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bb0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The influence of a company hearing conservation program on extra-auditory problems in workers" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A. Cohen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Safety Res" "fecha" => "1976" "volumen" => "8" "paginaInicial" => "146" "paginaFinal" => "162" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bb0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of infrasound on lung structure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "V.I. Svigovyi" 1 => "V.V. Glinchikov" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Gig Truda Prof Zabol" "fecha" => "1987" "volumen" => "1" "paginaInicial" => "34" "paginaFinal" => "37" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bb0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Vibroacoustic disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "N.A.A. Castelo Branco" 1 => "M. Alves-pereira" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/bioinformatics/btv520" "Revista" => array:7 [ "tituloSerie" => "Noise & Health" "fecha" => "2004" "volumen" => "6" "numero" => "23" "paginaInicial" => "3" "paginaFinal" => "20" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26342229" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bb0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The vibroacoustic disease – An emerging pathology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "N.A.A. Castelo Branco" 1 => "E. Rodriguez Lopez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Aviat Space Environ Med" "fecha" => "1999" "volumen" => "70" "numero" => "3, Suppl" "paginaInicial" => "A1" "paginaFinal" => "A6" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10189150" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bb0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The clinical stages of vibroacoustic disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Aviat Space Environ Med" "fecha" => "1999" "volumen" => "70" "numero" => "3, Suppl" "paginaInicial" => "A32" "paginaFinal" => "A39" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10189154" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bb0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A unique case of vibroacoustic disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "A tribute to an extraordinary patient. Aviat Space Environ Med" "fecha" => "1999" "volumen" => "70" "numero" => "3, Suppl" "paginaInicial" => "A27" "paginaFinal" => "A31" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10189153" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bb0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of low frequency noise upon the reaction of pleural milky spots to mycobacterial infection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M.J.R. Oliveira" 1 => "A. Sousa Pereira" 2 => "A.P. Águas" 3 => "E. Monteiro" 4 => "N.R. Grande" 5 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Aviat Space Environ Med" "fecha" => "1999" "volumen" => "70" "numero" => "Suppl" "paginaInicial" => "A137" "paginaFinal" => "A140" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10189171" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bb0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Morphofunctional study of rat pleural mesothelial cells exposed to low frequency noise" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Sousa Pereira" 1 => "N.R. Grande" 2 => "M.S.N. Castelo Branco" 3 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:8 [ "tituloSerie" => "Aviat Space Environ Med" "fecha" => "1999" "volumen" => "70" "numero" => "3, Suppl" "paginaInicial" => "A78" "paginaFinal" => "A85" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10189160" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S188558571400200X" "estado" => "S300" "issn" => "18855857" ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bb0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Morphological changes in the rat lung parenchyma exposed to low frequency noise" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "N. Grande" 1 => "A.P. Águas" 2 => "A. Sousa Pereira" 3 => "E. Monteiro" 4 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:8 [ "tituloSerie" => "Aviat Space Environ Med" "fecha" => "1999" "volumen" => "70" "numero" => "3, Suppl" "paginaInicial" => "A70" "paginaFinal" => "A77" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10189159" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S030089321100594X" "estado" => "S300" "issn" => "03008932" ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bb0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of low frequency noise on rat tracheal epithelium" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Sousa Pereira" 1 => "A. Águas" 2 => "N.R. Grande" 3 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "AviatSpace Environ Med" "fecha" => "1999" "volumen" => "70" "numero" => "3, Suppl" "paginaInicial" => "A86" "paginaFinal" => "A90" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bb0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Airflow limitations in patients with vibroacoustic disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.M. Reis Ferreira" 1 => "A.R. Couto" 2 => "N. Jalles-Tavares" 3 => "M.S.N. Castelo Branco" 4 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Aviat Space Environ Med" "fecha" => "1999" "volumen" => "70" "numero" => "3, Suppl" "paginaInicial" => "A63" "paginaFinal" => "A69" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10189158" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bb0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "SEM and TEM study of rat respiratory epithelia exposed to low frequency noise" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "N.A.A. Castelo Branco" 1 => "M. Alves-Pereira" 2 => "J. Martins dos Santos" 3 => "E. Monteiro" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "paginaInicial" => "505" "paginaFinal" => "533" "serieVolumen" => "II" "serieTitulo" => "Science and Technology Education in Microscopy: An Overview" "serieFecha" => "2002" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bb0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Respiratory epithelia in Wistar rats born in low frequency noise plus varying amounts of additional exposure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "N.A.A. Castelo Branco" 1 => "E. Monteiro" 2 => "A. Costa e Silva" 3 => "J. Reis Ferreira" 4 => "M. Alves-Pereira" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Rev Port Pneumol" "fecha" => "2003" "volumen" => "IX" "numero" => "6" "paginaInicial" => "481" "paginaFinal" => "492" "itemHostRev" => array:3 [ "pii" => "S188558571300306X" "estado" => "S300" "issn" => "18855857" ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bb0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Respiratory epithelia in Wistar rats after 48 hours of continuous exposure to low frequency noise" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "N.A.A. Castelo Branco" 1 => "P. Gomes-Ferreira" 2 => "E. Monteiro" 3 => "A. Costa e Silva" 4 => "J. Reis Ferreira" 5 => "M. Alves-Pereira" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Port Pneumol" "fecha" => "2003" "volumen" => "IX" "numero" => "6" "paginaInicial" => "473" "paginaFinal" => "479" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bb0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The lung parenchyma in low frequency noise exposed rats" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "N.A.A. Castelo Branco" 1 => "E. Monteiro" 2 => "A. Costa e Silva" 3 => "J. Reis Ferreira" 4 => "M. Alves-Pereira" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Port Pneumol" "fecha" => "2004" "volumen" => "X" "numero" => "1" "paginaInicial" => "77" "paginaFinal" => "85" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bb0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Noise and the respiratory system" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Alves-Pereira" 1 => "J. Reis Ferreira" 2 => "J. Joanaz de Melo" 3 => "J. Motylewski" 4 => "E. Kotlicka" 5 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Port Pneumol" "fecha" => "2003" "volumen" => "IX" "numero" => "5" "paginaInicial" => "367" "paginaFinal" => "379" ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bb0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Vibroacoustic disease and respiratory pathology I – Tumours" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C.P. Mendes" 1 => "J. Reis Ferreira" 2 => "M. Alves-Pereira" 3 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:3 [ "paginaInicial" => "5" "conferencia" => "Proc Internoise" "serieFecha" => "2004" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bb0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnosis of vibroacoustic disease – preliminary report" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:7 [ 0 => "J. Reis Ferreira" 1 => "C.P. Mendes" 2 => "M. Antunes" 3 => "A.J.F. Martinho Pimenta" 4 => "E. Monteiro" 5 => "M. Alves-Pereira" 6 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "paginaInicial" => "112" "paginaFinal" => "114" "conferencia" => "Proc 8th Intern Cong Noise as a Public Health Problem, July, Rotterdam, Holland" "serieFecha" => "2003" ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bb0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Changes of the brainstem auditory evoked potentials induced by occupational vibration" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.H. Marvão" 1 => "M.S.N. Castelo Branco" 2 => "A. Entrudo" 3 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Soc Ciências Med" "fecha" => "1985" "volumen" => "149" "paginaInicial" => "478" "paginaFinal" => "486" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bb0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Vibroacoustic disease and respiratory pathology III – Tracheal and bronchial lesions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M.B. Monteiro" 1 => "J. Reis Ferreira" 2 => "C.P. Mendes" 3 => "M. Alves-Pe-reira" 4 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:3 [ "paginaInicial" => "5" "conferencia" => "Proc Internoise" "serieFecha" => "2004" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bb0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Air pollutants and other stressors as confounding or aggravating factors in noise –induced health problems" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D. Schwela" 1 => "S. Kephalopoulos" 2 => "D. Prasher" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:3 [ "paginaInicial" => "10" "conferencia" => "Proc Internoise" "serieFecha" => "2004" ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bb0120" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mechanobiology and diseases of mechanotransduction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.E. Ingber" ] ] ] ] ] "host" => array:2 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Med" "fecha" => "2003" "volumen" => "35" "paginaInicial" => "1" "paginaFinal" => "14" "itemHostRev" => array:3 [ "pii" => "S1885585714001376" "estado" => "S300" "issn" => "18855857" ] ] ] 1 => array:1 [ "WWW" => array:1 [ "link" => "http://web1.tch.harvard.edu/research/ingber/homepage.htm" ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bb0125" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mechanochemical basis of cell and tissue regulation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.E. Ingber" ] ] ] ] ] "host" => array:2 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "NAE Bridge" "fecha" => "2004" "volumen" => "34" "numero" => "3" "paginaInicial" => "4" "paginaFinal" => "10" ] ] 1 => array:1 [ "WWW" => array:1 [ "link" => "http://www.nae.edu/NAE/bridgecom.nsf/weblinks/MKEZ65RHQL?" ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bb0130" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Global cytoskeletal control of mechanotransduction in kidney epithelial cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "F.J. Alenghat" 1 => "S.M. Nauli" 2 => "R. Kolb" 3 => "J. Zhou" 4 => "D.E. Ingber" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.yexcr.2004.08.003" "Revista" => array:6 [ "tituloSerie" => "Exp Cell Res" "fecha" => "2004" "volumen" => "301" "paginaInicial" => "23" "paginaFinal" => "30" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15501441" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bb0135" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Vibroacoustic disease: biological effects of ultrasound and low frequency noise explained by mechanotransduction cellular signalling" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Alves-Pereira" 1 => "N.A.A. Castelo Branco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:2 [ "titulo" => "Prog Biophy Molec Biol" "fecha" => "2006" ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "pt" "url" => "/08732159/0000001300000001/v1_201509071333/S087321591530341X/v1_201509071333/pt/main.assets" "Apartado" => array:4 [ "identificador" => "43356" "tipo" => "SECCION" "pt" => array:2 [ "titulo" => "Artigos de revisão" "idiomaDefecto" => true ] "idiomaDefecto" => "pt" ] "PDF" => "https://static.elsevier.es/multimedia/08732159/0000001300000001/v1_201509071333/S087321591530341X/v1_201509071333/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S087321591530341X?idApp=UINPBA00004E" ]
Article information
ISSN: 08732159Original language: Portuguese
The statistics are updated each day
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 6 | 7 | 13 |
| 2024 October | 43 | 25 | 68 |
| 2024 September | 28 | 27 | 55 |
| 2024 August | 38 | 34 | 72 |
| 2024 July | 44 | 32 | 76 |
| 2024 June | 18 | 25 | 43 |
| 2024 May | 31 | 24 | 55 |
| 2024 April | 35 | 24 | 59 |
| 2024 March | 31 | 24 | 55 |
| 2024 February | 40 | 27 | 67 |
| 2024 January | 25 | 20 | 45 |
| 2023 December | 24 | 17 | 41 |
| 2023 November | 31 | 28 | 59 |
| 2023 October | 20 | 24 | 44 |
| 2023 September | 48 | 27 | 75 |
| 2023 August | 32 | 15 | 47 |
| 2023 July | 26 | 30 | 56 |
| 2023 June | 22 | 21 | 43 |
| 2023 May | 29 | 27 | 56 |
| 2023 April | 28 | 10 | 38 |
| 2023 March | 27 | 22 | 49 |
| 2023 February | 25 | 25 | 50 |
| 2023 January | 27 | 17 | 44 |
| 2022 December | 30 | 23 | 53 |
| 2022 November | 39 | 24 | 63 |
| 2022 October | 38 | 25 | 63 |
| 2022 September | 21 | 22 | 43 |
| 2022 August | 29 | 33 | 62 |
| 2022 July | 27 | 29 | 56 |
| 2022 June | 18 | 20 | 38 |
| 2022 May | 37 | 33 | 70 |
| 2022 April | 29 | 36 | 65 |
| 2022 March | 16 | 22 | 38 |
| 2022 February | 18 | 22 | 40 |
| 2022 January | 29 | 28 | 57 |
| 2021 December | 19 | 27 | 46 |
| 2021 November | 29 | 24 | 53 |
| 2021 October | 19 | 19 | 38 |
| 2021 September | 25 | 25 | 50 |
| 2021 August | 21 | 21 | 42 |
| 2021 July | 16 | 17 | 33 |
| 2021 June | 28 | 21 | 49 |
| 2021 May | 19 | 25 | 44 |
| 2021 April | 34 | 42 | 76 |
| 2021 March | 38 | 12 | 50 |
| 2021 February | 50 | 16 | 66 |
| 2021 January | 30 | 9 | 39 |
| 2020 December | 19 | 16 | 35 |
| 2020 November | 43 | 19 | 62 |
| 2020 October | 36 | 13 | 49 |
| 2020 September | 46 | 25 | 71 |
| 2020 August | 55 | 20 | 75 |
| 2020 July | 72 | 22 | 94 |
| 2020 June | 61 | 27 | 88 |
| 2020 May | 53 | 19 | 72 |
| 2020 April | 33 | 14 | 47 |
| 2020 March | 30 | 9 | 39 |
| 2020 February | 38 | 26 | 64 |
| 2020 January | 46 | 21 | 67 |
| 2019 December | 44 | 15 | 59 |
| 2019 November | 43 | 16 | 59 |
| 2019 October | 56 | 20 | 76 |
| 2019 September | 47 | 15 | 62 |
| 2019 August | 45 | 20 | 65 |
| 2019 July | 32 | 17 | 49 |
| 2019 June | 39 | 13 | 52 |
| 2019 May | 42 | 24 | 66 |
| 2019 April | 41 | 29 | 70 |
| 2019 March | 88 | 13 | 101 |
| 2019 February | 67 | 16 | 83 |
| 2019 January | 39 | 16 | 55 |
| 2018 December | 34 | 10 | 44 |
| 2018 November | 7 | 0 | 7 |
| 2018 October | 19 | 0 | 19 |
| 2018 September | 8 | 9 | 17 |
| 2018 August | 37 | 17 | 54 |
| 2018 July | 26 | 25 | 51 |
| 2018 June | 41 | 16 | 57 |
| 2018 May | 35 | 24 | 59 |
| 2018 April | 43 | 24 | 67 |
| 2018 March | 28 | 30 | 58 |
| 2018 February | 9 | 9 | 18 |
| 2018 January | 15 | 11 | 26 |
| 2017 December | 15 | 19 | 34 |
| 2017 November | 21 | 10 | 31 |
| 2017 October | 22 | 21 | 43 |
| 2017 September | 17 | 15 | 32 |
| 2017 August | 15 | 19 | 34 |
| 2017 July | 12 | 9 | 21 |
| 2017 June | 23 | 16 | 39 |
| 2017 May | 31 | 6 | 37 |
| 2017 April | 10 | 4 | 14 |
| 2017 March | 18 | 15 | 33 |
| 2017 February | 7 | 8 | 15 |
| 2017 January | 14 | 4 | 18 |
| 2016 December | 11 | 5 | 16 |
| 2016 November | 9 | 5 | 14 |
| 2016 October | 20 | 9 | 29 |
| 2016 September | 6 | 3 | 9 |
| 2016 August | 3 | 3 | 6 |
| 2016 July | 4 | 4 | 8 |
| 2016 June | 0 | 7 | 7 |
| 2016 May | 3 | 11 | 14 |
| 2016 April | 8 | 1 | 9 |
| 2016 March | 4 | 5 | 9 |
| 2016 February | 3 | 5 | 8 |
| 2016 January | 4 | 7 | 11 |
| 2015 December | 6 | 2 | 8 |
| 2015 November | 1 | 1 | 2 |
| 2015 October | 4 | 1 | 5 |
Show all
