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array:23 [ "pii" => "S0873215915303743" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)30374-3" "estado" => "S350" "fechaPublicacion" => "2007-11-01" "aid" => "1" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "copyrightAnyo" => "2007" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "Rev Port Pneumol. 2007;13:763-74" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2970 "formatos" => array:3 [ "EPUB" => 254 "HTML" => 1786 "PDF" => 930 ] ] "itemSiguiente" => array:19 [ "pii" => "S0873215915303755" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)30375-5" "estado" => "S350" "fechaPublicacion" => "2007-11-01" "aid" => "2" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "Rev Port Pneumol. 2007;13:775-87" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2393 "formatos" => array:3 [ "EPUB" => 208 "HTML" => 1497 "PDF" => 688 ] ] "pt" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Artigo Original / Original Article</span>" "titulo" => "Tromboembolismo pulmonar e asma de difícil controlo" "tienePdf" => "pt" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "pt" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "775" "paginaFinal" => "787" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Pulmonary embolism and difficult-to-treat asthma" ] ] "contieneResumen" => array:2 [ "pt" => true "en" => true ] "contienePdf" => array:1 [ "pt" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Catarina Teles Martins, Carlos Lopes, Alda Manique, Dolores Moniz, Renato Sotto-Mayor, A Bugalho de Almeida" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Catarina Teles" "apellidos" => "Martins" ] 1 => array:2 [ "nombre" => "Carlos" "apellidos" => "Lopes" ] 2 => array:2 [ "nombre" => "Alda" "apellidos" => "Manique" ] 3 => array:2 [ "nombre" => "Dolores" "apellidos" => "Moniz" ] 4 => array:2 [ "nombre" => "Renato" "apellidos" => "Sotto-Mayor" ] 5 => array:2 [ "nombre" => "A Bugalho" "apellidos" => "de Almeida" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915303755?idApp=UINPBA00004E" "url" => "/08732159/0000001300000006/v1_201509151528/S0873215915303755/v1_201509151528/pt/main.assets" ] "pt" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Artigo Original / Original Article</span>" "titulo" => "A importância do estudo da difusão alvéolo-capilar, como complemento da pletismografia, na avaliação funcional de fumadores" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "763" "paginaFinal" => "774" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "António Paes Cardoso, José Manuel Reis Ferreira, Álvaro Moreira da Silva" "autores" => array:3 [ 0 => array:3 [ "nombre" => "António Paes" "apellidos" => "Cardoso" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "af0005" ] ] ] 1 => array:3 [ "nombre" => "José Manuel Reis" "apellidos" => "Ferreira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "af0010" ] ] ] 2 => array:3 [ "nombre" => "Álvaro Moreira" "apellidos" => "da Silva" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "af0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Pneumologista e Professor auxiliar convidado da Cadeira de Fisiologia Humana – Universidade do Porto – ICBAS (Instituto de Ciências Biomédicas de Abel Salazar). Consultor de fisiopatologia respiratória do Hospital Geral de Santo António / <span class="elsevierStyleItalic">Pulmonologist and guest professor, Human Physiology – Porto University – ICBAS (Instituto de Ciências Biomédicas de Abel Salazar). Consultant in Respiratory Physiopathology, Santo António Hospital</span>" "etiqueta" => "1" "identificador" => "af0005" ] 1 => array:3 [ "entidad" => "Pneumologista e chefe de Serviço de Pneumologia do Hospital da Força Aérea, responsável pelo Laboratório de Função Pulmonar. Director Clínico da Clínica de Doentes Pulmonares, Lisboa / <span class="elsevierStyleItalic">Pulmonologist and head of the Pulmonology unit of the Portuguese Air Force Hospital. Head of the Pulmonary Function Laboratory. Clinical Director of the Pulmonary Clinic, Lisbon</span>" "etiqueta" => "2" "identificador" => "af0010" ] 2 => array:3 [ "entidad" => "Chefe de Serviço do Serviço de Cuidados Intensivos do Hospital Geral de Santo António. Assistente Convidado de Clínica Médica II (Pneumologia). Responsável pelo laboratório de Função Pulmonar do Hospital Geral de Santo António/ <span class="elsevierStyleItalic">Head of the ICU at Santo António Hospital. Guest professor, Medical Clinic II (Pulmonology). Head of the Pulmonary Function Laboratory, Santo António Hospital</span>" "etiqueta" => "3" "identificador" => "af0015" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "The importance of diffusing capacity as a complementary study to plethysmography in smokers" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-06-27" "fechaAceptado" => "2007-09-12" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec570423" "palabras" => array:4 [ 0 => "Transferência alvéolo-capilar" 1 => "<span class="elsevierStyleItalic">single breath</span>" 2 => "pletismografia" 3 => "fumadores" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec570424" "palabras" => array:4 [ 0 => "Alveolar-capillary transfer" 1 => "single breath" 2 => "plethysmography" 3 => "smokers" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Foram estudados 194 casos de fumadores e exfumadores (≥ 1 UMA), de ambos os sexos e idades compreendidas entre os 20 e os 82 anos, tendo sido excluídos doentes detentores de patologias ou antecedentes profissionais de risco. Apresentavam grau variado de sintomatologia e exame pletismográfico normal, mas com valores anormais do factor de transferência alvéolo-capilar, determinados pelo método de <span class="elsevierStyleItalic">single breath</span> com CO (TL<span class="elsevierStyleInf">CO</span> SB e TL<span class="elsevierStyleInf">CO</span> /VA). Dos 194 casos avaliados, 136 (70,1%) tinham valores anormais de um ou dos dois parâmetros referidos. No tratamento estatístico da amostra (teste do qui-quadrado), a diferença da sensibilidade entre ambos os parâmetros foi significativa (p<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>0,0001). As eventuais limitações do método de avaliação usado (<span class="elsevierStyleItalic">single breath</span>) foram, no presente estudo, minimizadas (restrição ventilatória com capacidade vital<span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>1,5 litros), pela normalidade referida do exame pletismográfico. De igual modo, a presença de alterações da distribuição ventilatória foi, em princípio, excluída pela ausência de valores da relação CPT-sb/CPTplet inferiores a 0,85.</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclusões:</span> A normalidade do exame pletismográfico em grandes fumadores ou ex-fumadores não é suficiente para afirmar uma normalidade da função respiratória, visto que grande percentagem de casos apresenta anormalidades do factor de transferência alvéolo-capilar pelo CO. A limitação alveolar considerada foi, não só a anatómica, mas, igualmente, a de carácter funcional.</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2007; XIII (6): 763-774</span></p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall">This study comprised 194 male and female heavy smokers or ex-smokers (≥ 1 pack-year) aged between 20 and 82, whose symptoms varied. Cases were only selected from patients with normal whole-body plethysmography. Subjects with any significant pathology and occupational risk factors were excluded from the study.</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">Varying degrees of symptoms were found and a range of results from normal plethysmography examination, with abnormal levels of alveolar-capillary transfer, determined by the single-breath method to analyse CO (TL<span class="elsevierStyleInf">CO</span> and TL<span class="elsevierStyleInf">CO</span> -VA) coefficients. Using the chi-square test for statistical analysis of the sample revealed a significant variation in sensitivity between both parameters (p<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>0.0001).</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall">Possible limitations of using the single-breath method, of were reduced in this study (ventilatory restriction withVital Capacity <<span class="elsevierStyleHsp" style=""></span>1.5 litres) by the routine plethysmography results seen. Likewise, the presence of alterations in ventilatory distribution was, in principle, minimised by the absence of TLCsb/TLCplet values below 0.85%</p><p id="sp0035" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclusions</span>: Normal plethysmography results in heavy or ex-smokers are not enough to confirm normal respiratory function, as a large percentage of cases present abnormalities in the alveolar-capillary transfer factor for CO. Alveolar limitation was considered not only anatomically, but also from a functional perspective.</p><p id="sp0040" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2007; XIII (6): 763-774</span></p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0025">Bibliografia / Bibliography</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:31 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ventilation inhomogeneity in α1-antitrypsin-deficient emphysema" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "L. Fregonese" 1 => "H.P.A.A. Van Veen" 2 => "P.J. Sterk" 3 => "J. 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Original language: Portuguese
Year/Month | Html | Total | |
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2024 November | 15 | 4 | 19 |
2024 October | 115 | 30 | 145 |
2024 September | 104 | 25 | 129 |
2024 August | 136 | 35 | 171 |
2024 July | 65 | 34 | 99 |
2024 June | 93 | 23 | 116 |
2024 May | 100 | 46 | 146 |
2024 April | 114 | 34 | 148 |
2024 March | 81 | 27 | 108 |
2024 February | 65 | 25 | 90 |
2024 January | 65 | 29 | 94 |
2023 December | 71 | 28 | 99 |
2023 November | 68 | 40 | 108 |
2023 October | 84 | 39 | 123 |
2023 September | 62 | 26 | 88 |
2023 August | 62 | 27 | 89 |
2023 July | 66 | 34 | 100 |
2023 June | 67 | 17 | 84 |
2023 May | 93 | 28 | 121 |
2023 April | 76 | 24 | 100 |
2023 March | 107 | 40 | 147 |
2023 February | 77 | 20 | 97 |
2023 January | 64 | 21 | 85 |
2022 December | 49 | 19 | 68 |
2022 November | 105 | 33 | 138 |
2022 October | 59 | 26 | 85 |
2022 September | 47 | 35 | 82 |
2022 August | 51 | 50 | 101 |
2022 July | 41 | 42 | 83 |
2022 June | 42 | 25 | 67 |
2022 May | 67 | 42 | 109 |
2022 April | 50 | 26 | 76 |
2022 March | 63 | 41 | 104 |
2022 February | 68 | 24 | 92 |
2022 January | 75 | 37 | 112 |
2021 December | 26 | 36 | 62 |
2021 November | 39 | 27 | 66 |
2021 October | 86 | 59 | 145 |
2021 September | 37 | 33 | 70 |
2021 August | 32 | 23 | 55 |
2021 July | 34 | 21 | 55 |
2021 June | 49 | 25 | 74 |
2021 May | 85 | 32 | 117 |
2021 April | 168 | 57 | 225 |
2021 March | 77 | 32 | 109 |
2021 February | 77 | 20 | 97 |
2021 January | 51 | 20 | 71 |
2020 December | 40 | 14 | 54 |
2020 November | 49 | 18 | 67 |
2020 October | 23 | 9 | 32 |
2020 September | 67 | 17 | 84 |
2020 August | 78 | 27 | 105 |
2020 July | 73 | 8 | 81 |
2020 June | 70 | 25 | 95 |
2020 May | 82 | 20 | 102 |
2020 April | 79 | 17 | 96 |
2020 March | 72 | 15 | 87 |
2020 February | 60 | 20 | 80 |
2020 January | 60 | 16 | 76 |
2019 December | 49 | 21 | 70 |
2019 November | 64 | 13 | 77 |
2019 October | 57 | 25 | 82 |
2019 September | 63 | 16 | 79 |
2019 August | 89 | 21 | 110 |
2019 July | 70 | 20 | 90 |
2019 June | 62 | 33 | 95 |
2019 May | 76 | 55 | 131 |
2019 April | 64 | 57 | 121 |
2019 March | 123 | 33 | 156 |
2019 February | 112 | 22 | 134 |
2019 January | 92 | 34 | 126 |
2018 December | 57 | 12 | 69 |
2018 November | 4 | 5 | 9 |
2018 October | 6 | 0 | 6 |
2018 September | 16 | 8 | 24 |
2018 August | 41 | 34 | 75 |
2018 July | 33 | 32 | 65 |
2018 June | 51 | 25 | 76 |
2018 May | 47 | 25 | 72 |
2018 April | 67 | 50 | 117 |
2018 March | 31 | 33 | 64 |
2018 February | 31 | 4 | 35 |
2018 January | 34 | 26 | 60 |
2017 December | 31 | 14 | 45 |
2017 November | 34 | 15 | 49 |
2017 October | 33 | 7 | 40 |
2017 September | 36 | 10 | 46 |
2017 August | 25 | 17 | 42 |
2017 July | 18 | 7 | 25 |
2017 June | 24 | 12 | 36 |
2017 May | 36 | 15 | 51 |
2017 April | 8 | 46 | 54 |
2017 March | 16 | 66 | 82 |
2017 February | 9 | 7 | 16 |
2017 January | 13 | 6 | 19 |
2016 December | 12 | 3 | 15 |
2016 November | 7 | 3 | 10 |
2016 October | 11 | 6 | 17 |
2016 September | 3 | 2 | 5 |
2016 August | 3 | 1 | 4 |
2016 July | 3 | 4 | 7 |
2016 May | 1 | 3 | 4 |
2016 April | 1 | 8 | 9 |
2016 March | 3 | 10 | 13 |
2016 February | 7 | 16 | 23 |
2016 January | 4 | 4 | 8 |
2015 December | 8 | 9 | 17 |
2015 November | 1 | 3 | 4 |
2015 October | 3 | 2 | 5 |