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"titulo" => "Adenocarcinoma do pulmão: Aplicação da classificação WHO 1999/2004 à casuística do Serviço de Anatomia Patológica do Hospital da Universidade de Coimbra" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "255" "paginaFinal" => "268" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "Sónia Carvalho, Ricardo Branco, Pedro Serralheiro, Tiago Saraiva, Lina Carvalho" "autores" => array:5 [ 0 => array:3 [ "nombre" => "Sónia" "apellidos" => "Carvalho" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">#</span>" "identificador" => "af0005" ] ] ] 1 => array:3 [ "nombre" => "Ricardo" "apellidos" => "Branco" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">#</span>" "identificador" => "af0005" ] ] ] 2 => array:3 [ "nombre" => "Pedro" "apellidos" => "Serralheiro" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">#</span>" "identificador" => "af0005" ] ] ] 3 => array:3 [ "nombre" => "Tiago" "apellidos" => "Saraiva" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">#</span>" "identificador" => "af0005" ] ] ] 4 => array:3 [ "nombre" => "Lina" "apellidos" => "Carvalho" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "af0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Alunos do 6º ano da licenciatura em Medicina – Oncologia, Serviço de Anatomia Patológica do HUC – Directora: Dra. Fernanda Xavier da Cunha" "etiqueta" => "#" "identificador" => "af0005" ] 1 => array:3 [ "entidad" => "Professora de Anatomia Patológica, Serviço de Anatomia Patológica do HUC – Directora: Dra. Fernanda Xavier da Cunha" "etiqueta" => "*" "identificador" => "af0010" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-03-02" "fechaAceptado" => "2006-03-09" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec567783" "palabras" => array:3 [ 0 => "Adenocarcinoma do pulmão" 1 => "metátases pulmonares" 2 => "classificação WHO" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec567782" "palabras" => array:3 [ 0 => "Adenocarcinoma of the lung" 1 => "pulmonary metastasis" 2 => "WHO classification" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Num período de quinze anos, entre 1990 e 2004, foram diagnosticados 701 adenocarcinomas primários do pulmão no Serviço de Anatomia Patológica do Hospital da Universidade de Coimbra e 382 metástases de carcinomas, com predomínio do cólon (119) e mama (66). Os adenocarcinomas do pulmão tiveram um aumento relativo no sexo masculino, com crescimento de 16 casos em 1990 para 49 em 2004, e no sexo feminino verificou-se um aumento de 12 para 37 no mesmo período e, assim, a partir de 2001, a incidência foi equivalente em ambos os sexos.</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall">Também nos últimos quatro anos, o grupo etário de incidência dos adenocarcinomas passou para os 70 anos, havendo casos diagnosticados em doentes com idade superior a 80 anos.</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">Acompanhando o estudo numérico dos adenocarcinomas, foi feita a respectiva reclassificação histológica para aplicação dos critérios de diagnóstico estabelecidos pela classificação da OMS 1999-2004 para os tumores do pulmão, pleura, timo e coração. A incidência dos carcinomas bronquíoloalveolares foi naturalmente maior no sexo feminino, enquanto no sexo masculino, se verificou um maior número de adenocarcinomas acinares. Estas conclusões foram retiradas dos diagnósticos obtidos nas peças cirúrgicas e quando em biópsias cirúrgicas se considerou a amostra representativa. O estadiamento cirúrgico predominou entre IIA e IIIB e, em 109 casos, o diagnóstico possível foi apenas de adenocarcinoma do pulmão, por falta de amostragem e com imuno-histoquímica concordante.</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2006; XII (3): 255-268</span></p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">A study of 701 primary adenocarcinomas of the lung was made at the Department of Pathology of the Hospital da Universidade de Coimbra for a period of fifteen years, between 1990 and 2004. In the same period 382 metastases were diagnosed, mainly from colon (119) and breast (66). The incidence of primary adenocarcinomas varied from 16 cases in 1990 to 49 cases in men and from 12 to 37 cases in women in that period. From 2001 onwards, the incidence was almost coincident in both genders. In the last four years, since 2001, patients were in the seventies at the time of diagnosis and a considerable number of cases were diagnosed after 80 years of age.</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall">The criteria defined by the WHO classification of Tumours of the Lung, Pleura, Thymus and Heart 2004 were applied to the primary adenocarcinomas of the lung and as was expected, bronchioloalveolar carcinomas had its incidence in women while acinar adenocarcinomas were diagnosed mainly in men. These conclusions were obtained via surgical specimens and when surgical biopsies were representative and those were mainly in stage IIB and IIIA. A number of 109 cases had the final diagnosis of adenocarcinoma of the lung based on morphology and immunohistochemistry criteria.</p><p id="sp0035" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2006; XII (3): 255-268</span></p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0025">Bibliografia</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:29 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The increasing incidence of lung adenocarcinoma: reality or artefact? A review of the epide-miology of lung cancer adenocarcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Charloux" 1 => "E. Quoix" 2 => "N. Vcblkove" 3 => "D. Small" 4 => "G. Pauli" 5 => "H. 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Original language: Portuguese
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 6 | 6 | 12 |
2024 October | 25 | 30 | 55 |
2024 September | 31 | 27 | 58 |
2024 August | 38 | 48 | 86 |
2024 July | 25 | 38 | 63 |
2024 June | 27 | 36 | 63 |
2024 May | 19 | 38 | 57 |
2024 April | 21 | 41 | 62 |
2024 March | 30 | 23 | 53 |
2024 February | 25 | 26 | 51 |
2024 January | 24 | 27 | 51 |
2023 December | 23 | 25 | 48 |
2023 November | 19 | 31 | 50 |
2023 October | 14 | 29 | 43 |
2023 September | 16 | 34 | 50 |
2023 August | 15 | 21 | 36 |
2023 July | 25 | 27 | 52 |
2023 June | 16 | 9 | 25 |
2023 May | 28 | 24 | 52 |
2023 April | 12 | 14 | 26 |
2023 March | 17 | 26 | 43 |
2023 February | 17 | 23 | 40 |
2023 January | 20 | 19 | 39 |
2022 December | 19 | 18 | 37 |
2022 November | 41 | 22 | 63 |
2022 October | 25 | 35 | 60 |
2022 September | 22 | 21 | 43 |
2022 August | 34 | 50 | 84 |
2022 July | 25 | 24 | 49 |
2022 June | 20 | 27 | 47 |
2022 May | 27 | 31 | 58 |
2022 April | 23 | 29 | 52 |
2022 March | 20 | 32 | 52 |
2022 February | 21 | 23 | 44 |
2022 January | 25 | 29 | 54 |
2021 December | 19 | 30 | 49 |
2021 November | 20 | 21 | 41 |
2021 October | 25 | 34 | 59 |
2021 September | 20 | 27 | 47 |
2021 August | 24 | 18 | 42 |
2021 July | 24 | 19 | 43 |
2021 June | 16 | 21 | 37 |
2021 May | 28 | 25 | 53 |
2021 April | 56 | 37 | 93 |
2021 March | 27 | 19 | 46 |
2021 February | 43 | 14 | 57 |
2021 January | 30 | 19 | 49 |
2020 December | 21 | 7 | 28 |
2020 November | 36 | 21 | 57 |
2020 October | 21 | 18 | 39 |
2020 September | 55 | 27 | 82 |
2020 August | 50 | 18 | 68 |
2020 July | 67 | 12 | 79 |
2020 June | 60 | 21 | 81 |
2020 May | 56 | 16 | 72 |
2020 April | 43 | 11 | 54 |
2020 March | 45 | 13 | 58 |
2020 February | 32 | 15 | 47 |
2020 January | 40 | 19 | 59 |
2019 December | 50 | 17 | 67 |
2019 November | 43 | 12 | 55 |
2019 October | 57 | 16 | 73 |
2019 September | 45 | 21 | 66 |
2019 August | 63 | 14 | 77 |
2019 July | 40 | 10 | 50 |
2019 June | 40 | 24 | 64 |
2019 May | 50 | 28 | 78 |
2019 April | 48 | 25 | 73 |
2019 March | 67 | 15 | 82 |
2019 February | 69 | 11 | 80 |
2019 January | 66 | 19 | 85 |
2018 December | 31 | 14 | 45 |
2018 November | 3 | 4 | 7 |
2018 October | 5 | 8 | 13 |
2018 September | 18 | 10 | 28 |
2018 August | 40 | 19 | 59 |
2018 July | 32 | 23 | 55 |
2018 June | 31 | 19 | 50 |
2018 May | 27 | 25 | 52 |
2018 April | 38 | 28 | 66 |
2018 March | 28 | 28 | 56 |
2018 February | 12 | 15 | 27 |
2018 January | 12 | 15 | 27 |
2017 December | 19 | 19 | 38 |
2017 November | 12 | 17 | 29 |
2017 October | 19 | 17 | 36 |
2017 September | 20 | 18 | 38 |
2017 August | 14 | 4 | 18 |
2017 July | 19 | 9 | 28 |
2017 June | 15 | 14 | 29 |
2017 May | 25 | 15 | 40 |
2017 April | 22 | 8 | 30 |
2017 March | 11 | 26 | 37 |
2017 February | 6 | 6 | 12 |
2017 January | 7 | 15 | 22 |
2016 December | 10 | 5 | 15 |
2016 November | 9 | 5 | 14 |
2016 October | 7 | 7 | 14 |
2016 September | 6 | 10 | 16 |
2016 August | 5 | 2 | 7 |
2016 July | 6 | 3 | 9 |
2016 May | 0 | 1 | 1 |
2016 April | 1 | 10 | 11 |
2016 March | 2 | 19 | 21 |
2016 February | 4 | 12 | 16 |
2016 January | 4 | 6 | 10 |
2015 December | 4 | 2 | 6 |
2015 November | 2 | 1 | 3 |
2015 October | 2 | 3 | 5 |