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Cadernos de Anatomia Patológica\Pathology Note Books
Adenocarcinoma do pulmão: Aplicação da classificação WHO 1999/2004 à casuística do Serviço de Anatomia Patológica do Hospital da Universidade de Coimbra
Sónia Carvalho#, Ricardo Branco#, Pedro Serralheiro#, Tiago Saraiva#, Lina Carvalho*
# Alunos do 6º ano da licenciatura em Medicina – Oncologia, Serviço de Anatomia Patológica do HUC – Directora: Dra. Fernanda Xavier da Cunha
* Professora de Anatomia Patológica, Serviço de Anatomia Patológica do HUC – Directora: Dra. Fernanda Xavier da Cunha
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        "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Num per&#237;odo de quinze anos&#44; entre 1990 e 2004&#44; foram diagnosticados 701 adenocarcinomas prim&#225;rios do pulm&#227;o no Servi&#231;o de Anatomia Patol&#243;gica do Hospital da Universidade de Coimbra e 382 met&#225;stases de carcinomas&#44; com predom&#237;nio do c&#243;lon &#40;119&#41; e mama &#40;66&#41;&#46; Os adenocarcinomas do pulm&#227;o tiveram um aumento relativo no sexo masculino&#44; com crescimento de 16 casos em 1990 para 49 em 2004&#44; e no sexo feminino verificou-se um aumento de 12 para 37 no mesmo per&#237;odo e&#44; assim&#44; a partir de 2001&#44; a incid&#234;ncia foi equivalente em ambos os sexos&#46;</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall">Tamb&#233;m nos &#250;ltimos quatro anos&#44; o grupo et&#225;rio de incid&#234;ncia dos adenocarcinomas passou para os 70 anos&#44; havendo casos diagnosticados em doentes com idade superior a 80 anos&#46;</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">Acompanhando o estudo num&#233;rico dos adenocarcinomas&#44; foi feita a respectiva reclassifica&#231;&#227;o histol&#243;gica para aplica&#231;&#227;o dos crit&#233;rios de diagn&#243;stico estabelecidos pela classifica&#231;&#227;o da OMS 1999-2004 para os tumores do pulm&#227;o&#44; pleura&#44; timo e cora&#231;&#227;o&#46; A incid&#234;ncia dos carcinomas bronqu&#237;oloalveolares foi naturalmente maior no sexo feminino&#44; enquanto no sexo masculino&#44; se verificou um maior n&#250;mero de adenocarcinomas acinares&#46; Estas conclus&#245;es foram retiradas dos diagn&#243;sticos obtidos nas pe&#231;as cir&#250;rgicas e quando em bi&#243;psias cir&#250;rgicas se considerou a amostra representativa&#46; O estadiamento cir&#250;rgico predominou entre IIA e IIIB e&#44; em 109 casos&#44; o diagn&#243;stico poss&#237;vel foi apenas de adenocarcinoma do pulm&#227;o&#44; por falta de amostragem e com imuno-histoqu&#237;mica concordante&#46;</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2006&#59; XII &#40;3&#41;&#58; 255-268</span></p></span>"
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Article information
ISSN: 08732159
Original language: Portuguese
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