Caso Clínico / Clinical Case
Pneumonia aguda fibrinosa e organizante
Acute fibrinous and organizing pneumonia
1 Interna Complementar de Pneumologia, Serviço de Pneumologia, Hospital de São João, EPE, Porto, Faculdade de Medicina da Universidade do Porto (FMUP)
2 Assistente Hospitalar de Pneumologia, Serviço de Pneumologia, Hospital de São João, EPE, Porto, Faculdade de Medicina da Universidade do Porto (FMUP)
3 Assistente Hospitalar de Anatomia Patológica, Serviço de Pneumologia, Hospital de São João, EPE, Porto, Faculdade de Medicina da Uniersidade do Porto (FMUP)
4 Chefe de Serviço de Pneumologia, Professor Catedrático de Pneumologia da FMUP, Director do Serviço de Pneumologia, Serviço de Pneumologia, Hospital de São João, EPE, Porto, Faculdade de Medicina da Universidade do Porto (FMUP)
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Damas, A. Morais, C.S. Moura, J.A. Marques" "autores" => array:4 [ 0 => array:3 [ "nombre" => "C." "apellidos" => "Damas" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "af0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cr0005" ] ] ] 1 => array:3 [ "nombre" => "A." "apellidos" => "Morais" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "af0010" ] ] ] 2 => array:3 [ "nombre" => "C.S." "apellidos" => "Moura" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "af0015" ] ] ] 3 => array:3 [ "nombre" => "J.A." "apellidos" => "Marques" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "af0020" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Interna Complementar de Pneumologia, Serviço de Pneumologia, Hospital de São João, EPE, Porto, Faculdade de Medicina da Universidade do Porto (FMUP)" "etiqueta" => "1" "identificador" => "af0005" ] 1 => array:3 [ "entidad" => "Assistente Hospitalar de Pneumologia, Serviço de Pneumologia, Hospital de São João, EPE, Porto, Faculdade de Medicina da Universidade do Porto (FMUP)" "etiqueta" => "2" "identificador" => "af0010" ] 2 => array:3 [ "entidad" => "Assistente Hospitalar de Anatomia Patológica, Serviço de Pneumologia, Hospital de São João, EPE, Porto, Faculdade de Medicina da Uniersidade do Porto (FMUP)" "etiqueta" => "3" "identificador" => "af0015" ] 3 => array:3 [ "entidad" => "Chefe de Serviço de Pneumologia, Professor Catedrático de Pneumologia da FMUP, Director do Serviço de Pneumologia, Serviço de Pneumologia, Hospital de São João, EPE, Porto, Faculdade de Medicina da Universidade do Porto (FMUP)" "etiqueta" => "4" "identificador" => "af0020" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cr0005" "etiqueta" => "*" "correspondencia" => "<span class="elsevierStyleBold">Correspondência/Correspondence to:</span> Carla Damas, Travessa Fernando Namora, 48 5.º Esq. 4425 Pedrouços – Maia, Portugal" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Acute fibrinous and organizing pneumonia" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-03-28" "fechaAceptado" => "2006-05-26" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec567832" "palabras" => array:2 [ 0 => "AFOP" 1 => "pneumonia organizativa" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec567833" "palabras" => array:2 [ 0 => "AFOP" 1 => "organizing pneumonia" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">A designação <span class="elsevierStyleItalic">acute fibrinous and organizing pneumonia (AFOP)</span> foi proposta por Beasley <span class="elsevierStyleItalic">et al</span> para os casos em que as características histopatológicas das lesões não se enquadravam em outras situações clínicas (agu-das ou subagudas) conhecidas. A presença de fibrina intra alveolar e de pneumonia organizativa, com distribuição difusa, é a principal alteração histológica associada a esta entidade.</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall">Os autores descrevem o caso de um doente do sexo masculino, com o diagnóstico de AFOP, por bióp-sia pulmonar cirúrgica. O doente teve uma apresentação subaguda, apresentando por queixas principais tosse, dor torácica e febre. TAC torácica mostrou infiltrados bilaterais, difusos. Após início de corticoterapia sistémica e ciclofosfamida, o doente apresentou melhoria clínica significativa. Ao elaborar este caso, os autores esperam acrescentar mais alguns dados sobre esta nova entidade.</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2006; XII (5): 615-620</span></p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall">The term Acute Fibrinous and Organizing Pneumonia (AFOP) has been proposed by Beasley <span class="elsevierStyleItalic">et al</span> for cases that not fit into the histopathologic criteria of the recognized entities described as acute or subacute clinical presentations. The presence of intra-alveolar fibrin in the form of fibrin ‘balls’ and organizing pneumonia with patchy distribution are the main histological features of this entity. We describe the case of a male patient with the diagnostic of AFOP made by surgical lung biopsy. He had a subacute presentation of symptoms consisting of productive cough, chest pain and fever. Bilateral infiltrates with patchy and diffuse distribution were the predominant features in his chest HRCT scan. The patient had a good clinical course after a treatment with prednisone and cyclophosphamide. Our hope in reporting this case study is to add some more data to the discussion of this new entity.</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2006; XII (5): 615-620</span></p></span>" ] ] "lecturaRecomendada" => array:1 [ 0 => array:3 [ "vista" => "all" "titulo" => "<span class="elsevierStyleSectionTitle" id="st0025">Bibliography</span>" "seccion" => array:1 [ 0 => array:2 [ "vista" => "all" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute Fibrinous and Organizing Pneumonia: a histologic pattern of lung injury and possible variant of difuse alveolar damage" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M.B. Beasley" 1 => "T.J. Franks" 2 => "J.R. Galvin" 3 => "B. Gochuico" 4 => "W.D. Travis" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1043/0003-9985(2002)126<1064:AFAOP>2.0.CO;2" "Revista" => array:7 [ "tituloSerie" => "Archives of Pathology and Laboratory Medicine" "fecha" => "2002" "volumen" => "126" "numero" => "9" "paginaInicial" => "1064" "paginaFinal" => "1070" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12204055" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bb0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Organizing Pneumonia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.F. Cordier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Thorax" "fecha" => "2002" "volumen" => "55" "paginaInicial" => "318" "paginaFinal" => "328" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10722773" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bb0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchiolar Disorders" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.H. Ryu" 1 => "J.L. Myers" 2 => "S.J. Swensen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Resp and Crit Care Med" "fecha" => "2003" "volumen" => "168" "paginaInicial" => "1277" "paginaFinal" => "2129" ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "pt" "url" => "/08732159/0000001200000005/v1_201509071315/S0873215915304530/v1_201509071315/pt/main.assets" "Apartado" => array:4 [ "identificador" => "43360" "tipo" => "SECCION" "pt" => array:2 [ "titulo" => "Casos Clínicos/Cases Reports" "idiomaDefecto" => true ] "idiomaDefecto" => "pt" ] "PDF" => "https://static.elsevier.es/multimedia/08732159/0000001200000005/v1_201509071315/S0873215915304530/v1_201509071315/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915304530?idApp=UINPBA00004E" ]
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ISSN: 08732159Original language: Portuguese
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