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array:24 [ "pii" => "S0873215915312484" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)31248-4" "estado" => "S350" "fechaPublicacion" => "2010-11-01" "aid" => "50000003" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "copyrightAnyo" => "2010" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "Rev Port Pneumol. 2010;16:870-9" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2330 "formatos" => array:3 [ "EPUB" => 227 "HTML" => 1490 "PDF" => 613 ] ] "itemSiguiente" => array:19 [ "pii" => "S0873215915312496" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)31249-6" "estado" => "S350" "fechaPublicacion" => "2010-11-01" "aid" => "50000004" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "Rev Port Pneumol. 2010;16:880-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2484 "formatos" => array:3 [ "EPUB" => 235 "HTML" => 1641 "PDF" => 608 ] ] "pt" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">ARTIGO ORIGINAL</span>" "titulo" => "Pandemia de gripe A (H1N1) no Norte de Portugal: características da onda de Outono/Inverno" "tienePdf" => "pt" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "pt" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "880" "paginaFinal" => "886" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Pandemic influenza A (H1N1) in the North of Portugal: how did the Autumn-Winter wave behave?" ] ] "contieneResumen" => array:2 [ "pt" => true "en" => true ] "contienePdf" => array:1 [ "pt" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A.M. Correia, L. Queirós, J. Dias" "autores" => array:3 [ 0 => array:2 [ "nombre" => "A.M." "apellidos" => "Correia" ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Queirós" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Dias" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915312496?idApp=UINPBA00004E" "url" => "/08732159/0000001600000006/v1_201509151455/S0873215915312496/v1_201509151455/pt/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S0873215915312472" "issn" => "08732159" "doi" => "10.1016/S0873-2159(15)31247-2" "estado" => "S350" "fechaPublicacion" => "2010-11-01" "aid" => "50000002" "copyright" => "Sociedade Portuguesa de Pneumologia/SPP" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "edi" "cita" => "Rev Port Pneumol. 2010;16:867-9" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3298 "formatos" => array:3 [ "EPUB" => 206 "HTML" => 2098 "PDF" => 994 ] ] "pt" => array:9 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">EDITORIAL</span>" "titulo" => "A year and two months of 2009 influenza pandemic" "tienePdf" => "pt" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "867" "paginaFinal" => "869" ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Um ano e dois meses de pandemia de gripe 2009" ] ] "contienePdf" => array:1 [ "pt" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "F. Froes, A. Diniz" "autores" => array:2 [ 0 => array:2 [ "nombre" => "F." "apellidos" => "Froes" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Diniz" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0873215915312472?idApp=UINPBA00004E" "url" => "/08732159/0000001600000006/v1_201509151455/S0873215915312472/v1_201509151455/pt/main.assets" ] "pt" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">ARTIGO ORIGINAL</span>" "titulo" => "Os dias iniciais da infecção pelo vírus da gripe pandémica (H1N1) 2009 na região centro de Portugal" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "870" "paginaFinal" => "879" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "V. Duque, E. Cordeiro, V. Mota, J. Vaz, C. Morais, F. Rodrigues, F. Coelho, J. Saraiva da Cunha, A. Meliço-Silvestre" "autores" => array:9 [ 0 => array:4 [ "nombre" => "V." "apellidos" => "Duque" "email" => array:1 [ 0 => "duque.vitor@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "af0005" ] ] ] 1 => array:3 [ "nombre" => "E." "apellidos" => "Cordeiro" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "af0010" ] ] ] 2 => array:3 [ "nombre" => "V." "apellidos" => "Mota" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "af0015" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Vaz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "af0020" ] ] ] 4 => array:3 [ "nombre" => "C." "apellidos" => "Morais" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">e</span>" "identificador" => "af0025" ] ] ] 5 => array:3 [ "nombre" => "F." "apellidos" => "Rodrigues" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">f</span>" "identificador" => "af0030" ] ] ] 6 => array:3 [ "nombre" => "F." "apellidos" => "Coelho" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">g</span>" "identificador" => "af0035" ] ] ] 7 => array:3 [ "nombre" => "J." "apellidos" => "Saraiva da Cunha" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">h</span>" "identificador" => "af0040" ] ] ] 8 => array:3 [ "nombre" => "A." "apellidos" => "Meliço-Silvestre" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">i</span>" "identificador" => "af0045" ] ] ] ] "afiliaciones" => array:9 [ 0 => array:3 [ "entidad" => "Serviço de Doenças Infecciosas dos Hospitais da Universidade de Coimbra, EPE, Laboratorio de Virologia dos Hospitais da Universidade de Coimbra, Faculdade de Medicina da Universidade de Coimbra, Coimbra, Portugal" "etiqueta" => "a" "identificador" => "af0005" ] 1 => array:3 [ "entidad" => "Epidemiologia, Departamento de Saúde Pública e Planeamento, Administração Regional de Saúde do Centro, IP, Portugal" "etiqueta" => "b" "identificador" => "af0010" ] 2 => array:3 [ "entidad" => "Laboratório de Virologia, Hospitais da Universidade de Coimbra, EPE, Coimbra, Portugal" "etiqueta" => "c" "identificador" => "af0015" ] 3 => array:3 [ "entidad" => "Laboratório de Virologia, Hospitais da Universidade de Coimbra, EPE, Coimbra, Portugal" "etiqueta" => "d" "identificador" => "af0020" ] 4 => array:3 [ "entidad" => "Departamento de Diagnóstico e Terapêutica, Laboratório de Virologia, Hospitais da Universidade de Coimbra, EPE, Coimbra, Portugal" "etiqueta" => "e" "identificador" => "af0025" ] 5 => array:3 [ "entidad" => "Pediatria, Unidade de Infecciologia e Serviço de Urgência, Hospital Pediátrico de Coimbra, Coimbra, Portugal" "etiqueta" => "f" "identificador" => "af0030" ] 6 => array:3 [ "entidad" => "Comissão de Higiene e Epidemiologia Infecciosa, Serviço de Doenças Infecciosas, Hospitais da Universidade de Coimbra, EPE, Coimbra, Portugal" "etiqueta" => "g" "identificador" => "af0035" ] 7 => array:3 [ "entidad" => "Serviço de Doencas Infecciosas, Hospitais da Universidade de Coimbra, EPE, Faculdade de Medicina da Universidade de Coimbra, Coimbra, Portugal" "etiqueta" => "h" "identificador" => "af0040" ] 8 => array:3 [ "entidad" => "Área de Gestão Integrada II, Hospitais da Universidade de Coimbra, EPE, Faculdade de Medicina da Universidade de Coimbra, Coimbra, Portugal" "etiqueta" => "i" "identificador" => "af0045" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "The early days of pandemic (H1N1) 2009 virus infection in the central region of Portugal" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2010-04-07" "fechaAceptado" => "2010-07-20" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:3 [ "clase" => "keyword" "identificador" => "xpalclavsec570230" "palabras" => array:6 [ 0 => "Palavras-Chave" 1 => "Gripe" 2 => "Influenza" 3 => "H1N1" 4 => "Pandemia" 5 => "2009" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec570231" "palabras" => array:4 [ 0 => "Influenza" 1 => "H1N1" 2 => "Pandemics" 3 => "2009" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:3 [ "titulo" => "Resumo" "resumen" => "<span id="as0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0015">Introdução</span><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">O primeiro caso de infecção pelo vírus da gripe pandémica (H1N1) 2009 foi diagnosticado na região centro de Portugal no dia 16 de Junho de 2009, numa mulher infectada no Canadá.</p></span> <span id="as0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0020">Métodos</span><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall">O nosso estudo tem por objectivos, em primeiro lugar caracterizar os aspectos clínicos e epidemiológicos de todos os doentes que tiveram manifestações clínicas incluídas na definição de caso para investigação com amostras submetidas para diagnóstico da infecção pelo vírus da gripe pandémica (H1N1) 2009; em segundo lugar, avaliar a precisão da definição de caso para investigação de acordo com a presença ou ausência de febre no momento da observação clinica. Efectuámos a revisão dos registos médicos de todos os doentes classificados como caso para investigação e analisaram-se os primeiros casos de doentes infectados com o novo vírus da gripe pandémica (H1N1) 2009, diagnosticados na região centro de Portugal durante o período pandémico compreendido entre Junho e Agosto de 2009.</p><p id="sp0035" class="elsevierStyleSimplePara elsevierViewall">Foi utilizado o método da reacção em cadeia da polimerase de retrotranscripção em tempo real para confirmação da infecção pelo vírus da gripe pandémica (H1N1) 2009. A colheita de dados foi efectuada de forma padronizada em suporte de papel de acordo com as normas da Direcçào Geral de Saúde.</p></span> <span id="as0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0025">Resultados e discussão</span><p id="sp0040" class="elsevierStyleSimplePara elsevierViewall">A infecção pelo vírus da gripe pandémica (H1N1) 2009 foi confirmada laboratorialmente em 255 casos. A idade média foi de 23 anos e 42,7 % foram incluídos na categoria dos 20 aos 29 anos. A infecção em doentes com menos de 2 anos ou mais de 50 anos foi um acontecimiento raro. Os primeiros casos foram importados da Europa: Franca, Espanha e Inglaterra. Numa segunda fase, a infecção foi adquirida no sul de Portugal (Algarve). A taxa de incidência de infecção pelo vírus da gripe pandémica (H1N1) 2009 foi de 10,7 por 100 000 pessoas e foi diferente consoante o distrito. Foi mais elevado no distrito de Coimbra e da Guarda onde estão as principais estradas de ligação com a Europa. O período de incubação calculado para a infecção pelo vírus da gripe pandémica (H1N1) 2009 foi de 2 dias. A duração das manifestações clínicas até os doentes procurarem observação médica teve um valor mediano de 2 dias. Todos os casos foram de gravidade ligeira a moderada, sem casos de morte.</p></span> <span id="as0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0030">Conclusões</span><p id="sp0045" class="elsevierStyleSimplePara elsevierViewall">Os dias iniciais da infecção pelo vírus da gripe pandémica (H1N1) 2009 foram caracterizados na nossa região por casos de doença com gravidade ligeira a moderada. Os mais afectados foram os jovens adultos, com as idades extremas da vida poupadas. O diagnóstico precoce, o isolamento estrito e o tratamento podem ter diminuído a disseminação da infecção.</p></span>" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "as0010" "titulo" => "Introdução" ] 1 => array:2 [ "identificador" => "as0015" "titulo" => "Métodos" ] 2 => array:2 [ "identificador" => "as0020" "titulo" => "Resultados e discussão" ] 3 => array:2 [ "identificador" => "as0025" "titulo" => "Conclusões" ] ] ] "en" => array:3 [ "titulo" => "Abstract" "resumen" => "<span id="as0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0040">Background</span><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">The first case of pandemic (H1N1) 2009 virus infection was diagnosed in the central region of Portugal on June 16, 2009, in a woman infected in Canada.</p></span> <span id="as0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0045">Methods</span><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall">The aim of our study was, first to characterize the clinical and epidemiologic aspects of all the patients with clinical manifestations included in the definition of case for investigation with samples submitted to diagnosis of the pandemic (H1N1) 2009 virus infection, in the central region of Portugal; second to assess the precision of the case definition of case for investigation considered in the study according to the presence or the absence of fever at the moment of clinical observation. We reviewed the medical records of all the patients presenting with Influenza like-illness classified as case for investigation and the first cases of patients infected with the new pandemic (H1N1) 2009 virus, diagnosed in the central region of Portugal during the pandemic period between June and August, 2009, were analyzed. Real-time reverse-transcriptase polymerase-chain-reaction (RT-PCR) testing was used to confirm the pandemic (H1N1) 2009 virus infection. Data collection was performed on a standardized paper format in agreement with the General Health Directorate.</p></span> <span id="as0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0050">Results and discussion</span><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">Pandemic (H1N1) 2009 virus infection was confirmed in 255 patients. Overall, median age was 23 years and 42.7<span class="elsevierStyleHsp" style=""></span>% were included in the category of 20 to 29 years. Confirmed infection in patients with less than 2 years or greater than 50 years was a rare event. The first cases were imported from Europe, namely France, Spain and England. On a second phase, pandemic (H1N1) 2009 virus infection was acquired in the south of Portugal (Algarve), before de diagnosis of the first domestic case. The incidence rate for pandemic (H1N1) 2009 virus infection was 10.7 per 100,000 persons and was different according to the district. It was higher in the district of Coimbra and Guarda were the main roads connecting to Europe are. The median calculated incubation period for the for pandemic (H1N1) 2009 virus infection was 2 days. The length of the clinical manifestations until the patients look for medical observation had a median time of 2 days. All the cases were of mild to moderate severity. No deaths were observed.</p></span> <span id="as0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0055">Conclusions</span><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall">The early days of pandemic (H1N1) 2009 virus infection was mild in our region. Most affected patients were young adults, with the extreme categories ages of life being spared. Early detection and diagnosis, combined with stringent isolation and treatment procedures could have slowed the spread of the infection in our region.</p></span>" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "as0030" "titulo" => "Background" ] 1 => array:2 [ "identificador" => "as0035" "titulo" => "Methods" ] 2 => array:2 [ "identificador" => "as0040" "titulo" => "Results and discussion" ] 3 => array:2 [ "identificador" => "as0045" "titulo" => "Conclusions" ] ] ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bs0005" "bibliografiaReferencia" => array:19 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1." 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"referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Pandemic Influenza – Inovations – Portugal. European Centre for Disease Prevention and Control. (Acedido a 3 de Fevereiro de 2010, em <a href="http://ecdc.europa.eu/en/healthtopics/pages/pandemic_influenza_innovations_portugal.aspx">http://ecdc.europa.eu/en/healthtopics/pages/pandemic_influenza_innovations_portugal.aspx</a>.)" ] ] ] 6 => array:3 [ "identificador" => "bb0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Gripe OT-1. (Acedido a 30 de Junho de 2010, em <a href="http://www.dgs.pt/ms/2/default.aspx?pl=&id=5509&acess=0&cpp=1">http://www.dgs.pt/ms/2/default.aspx?pl=&id=5509∾ess=0&cpp=1</a>.)." ] ] ] 7 => array:3 [ "identificador" => "bb0040" "etiqueta" => "8." 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Original language: Portuguese
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 5 | 4 | 9 |
2024 October | 37 | 27 | 64 |
2024 September | 33 | 22 | 55 |
2024 August | 39 | 39 | 78 |
2024 July | 29 | 38 | 67 |
2024 June | 21 | 22 | 43 |
2024 May | 24 | 34 | 58 |
2024 April | 26 | 32 | 58 |
2024 March | 28 | 21 | 49 |
2024 February | 36 | 20 | 56 |
2024 January | 22 | 32 | 54 |
2023 December | 26 | 26 | 52 |
2023 November | 17 | 26 | 43 |
2023 October | 14 | 25 | 39 |
2023 September | 25 | 29 | 54 |
2023 August | 22 | 18 | 40 |
2023 July | 17 | 44 | 61 |
2023 June | 22 | 16 | 38 |
2023 May | 21 | 23 | 44 |
2023 April | 25 | 12 | 37 |
2023 March | 51 | 23 | 74 |
2023 February | 21 | 28 | 49 |
2023 January | 22 | 17 | 39 |
2022 December | 28 | 16 | 44 |
2022 November | 36 | 40 | 76 |
2022 October | 26 | 20 | 46 |
2022 September | 16 | 29 | 45 |
2022 August | 33 | 48 | 81 |
2022 July | 20 | 34 | 54 |
2022 June | 17 | 34 | 51 |
2022 May | 34 | 35 | 69 |
2022 April | 18 | 30 | 48 |
2022 March | 26 | 39 | 65 |
2022 February | 21 | 32 | 53 |
2022 January | 15 | 41 | 56 |
2021 December | 21 | 39 | 60 |
2021 November | 25 | 35 | 60 |
2021 October | 17 | 40 | 57 |
2021 September | 28 | 29 | 57 |
2021 August | 20 | 22 | 42 |
2021 July | 30 | 23 | 53 |
2021 June | 11 | 26 | 37 |
2021 May | 21 | 28 | 49 |
2021 April | 66 | 35 | 101 |
2021 March | 27 | 25 | 52 |
2021 February | 26 | 15 | 41 |
2021 January | 26 | 12 | 38 |
2020 December | 7 | 15 | 22 |
2020 November | 47 | 20 | 67 |
2020 October | 22 | 12 | 34 |
2020 September | 43 | 21 | 64 |
2020 August | 65 | 21 | 86 |
2020 July | 77 | 19 | 96 |
2020 June | 48 | 22 | 70 |
2020 May | 66 | 15 | 81 |
2020 April | 56 | 10 | 66 |
2020 March | 44 | 11 | 55 |
2020 February | 40 | 21 | 61 |
2020 January | 50 | 12 | 62 |
2019 December | 41 | 15 | 56 |
2019 November | 35 | 17 | 52 |
2019 October | 50 | 13 | 63 |
2019 September | 45 | 18 | 63 |
2019 August | 85 | 18 | 103 |
2019 July | 68 | 14 | 82 |
2019 June | 61 | 22 | 83 |
2019 May | 82 | 26 | 108 |
2019 April | 57 | 23 | 80 |
2019 March | 75 | 11 | 86 |
2019 February | 66 | 11 | 77 |
2019 January | 80 | 28 | 108 |
2018 December | 37 | 4 | 41 |
2018 November | 9 | 2 | 11 |
2018 October | 5 | 7 | 12 |
2018 September | 21 | 16 | 37 |
2018 August | 36 | 33 | 69 |
2018 July | 29 | 18 | 47 |
2018 June | 41 | 19 | 60 |
2018 May | 48 | 20 | 68 |
2018 April | 42 | 38 | 80 |
2018 March | 46 | 32 | 78 |
2018 February | 20 | 13 | 33 |
2018 January | 20 | 7 | 27 |
2017 December | 33 | 21 | 54 |
2017 November | 33 | 9 | 42 |
2017 October | 26 | 21 | 47 |
2017 September | 29 | 19 | 48 |
2017 August | 22 | 15 | 37 |
2017 July | 19 | 11 | 30 |
2017 June | 21 | 14 | 35 |
2017 May | 31 | 11 | 42 |
2017 April | 15 | 2 | 17 |
2017 March | 14 | 2 | 16 |
2017 February | 16 | 7 | 23 |
2017 January | 13 | 7 | 20 |
2016 December | 21 | 4 | 25 |
2016 November | 7 | 5 | 12 |
2016 October | 11 | 4 | 15 |
2016 September | 3 | 3 | 6 |
2016 August | 3 | 3 | 6 |
2016 July | 3 | 1 | 4 |