array:24 [
  "pii" => "S2173511506704213"
  "issn" => "21735115"
  "doi" => "10.1016/S2173-5115(06)70421-3"
  "estado" => "S300"
  "fechaPublicacion" => "2006-09-01"
  "aid" => "70421"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2006"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "rev"
  "cita" => "Rev Port Pneumol. 2006;12:563-79"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3479
    "formatos" => array:3 [
      "EPUB" => 235
      "HTML" => 1768
      "PDF" => 1476
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173511506704225"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70422-5"
    "estado" => "S300"
    "fechaPublicacion" => "2006-09-01"
    "aid" => "70422"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "rev"
    "cita" => "Rev Port Pneumol. 2006;12:581-601"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4320
      "formatos" => array:3 [
        "EPUB" => 219
        "HTML" => 1660
        "PDF" => 2441
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Pneumonias intersticiais idiopáticas – Uma revisão da literatura"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "581"
          "paginaFinal" => "601"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Interstitial idiopathic pneumonias – A literature review"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Paulo José de Lima Mota"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "Paulo José"
              "apellidos" => "de Lima Mota"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704225?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000005/v1_201305151428/S2173511506704225/v1_201305151428/pt/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173511506704201"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70420-1"
    "estado" => "S300"
    "fechaPublicacion" => "2006-09-01"
    "aid" => "70420"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "rev"
    "cita" => "Rev Port Pneumol. 2006;12:545-61"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2755
      "formatos" => array:3 [
        "EPUB" => 232
        "HTML" => 1651
        "PDF" => 872
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Cancro do pulmão na mulher: Uma entidade diferente?"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "545"
          "paginaFinal" => "561"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Lung cancer in women: A different entity?"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Renato Sotto-Mayor"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "Renato"
              "apellidos" => "Sotto-Mayor"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704201?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000005/v1_201305151428/S2173511506704201/v1_201305151428/pt/main.assets"
  ]
  "pt" => array:14 [
    "idiomaDefecto" => true
    "titulo" => "Doenças inflamatórias alérgicas das vias aéreas superiores e suas implicações na asma brônquica – A propósito de um caso clínico"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "563"
        "paginaFinal" => "579"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Ana L. Fonseca, Ana M. Arrobas"
        "autores" => array:2 [
          0 => array:3 [
            "nombre" => "Ana L."
            "apellidos" => "Fonseca"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Ana M&#46;"
            "apellidos" => "Arrobas"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">2</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Interna do Complementar de Pneumologia&#44; Servi&#231;o de Pneumologia&#46; Director&#58; Dr&#46; Jorge Pires Hospital Geral do Centro Hospitalar de Coimbra Quinta dos Vales Coimbra"
            "etiqueta" => "<span class="elsevierStyleSup">1</span>"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Assistente Hospitalar Graduada de Pneumologia&#44; Servi&#231;o de Pneumologia&#46; Director&#58; Dr&#46; Jorge Pires Hospital Geral do Centro Hospitalar de Coimbra Quinta dos Vales Coimbra"
            "etiqueta" => "<span class="elsevierStyleSup">2</span>"
            "identificador" => "aff0010"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Allergic inflammatory diseases of the upper airways and their impact on asthma &#8211; Following on from a case report"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2006-02-02"
    "fechaAceptado" => "2006-05-18"
    "PalabrasClave" => array:2 [
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec158865"
          "palabras" => array:4 [
            0 => "Asma br&#244;nquica"
            1 => "rinite al&#233;rgica"
            2 => "sinusite cr&#243;nica"
            3 => "polipose nasal"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key-words"
          "identificador" => "xpalclavsec158864"
          "palabras" => array:4 [
            0 => "Asthma"
            1 => "allergic rhinitis"
            2 => "chronic sinusitis"
            3 => "nasal polyposis"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "pt" => array:2 [
        "titulo" => "Resumo"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Os autores apresentam o caso cl&#237;nico de uma doente referenciada &#224; consulta de alergologia respirat&#243;ria por &#8220;asma de dif&#237;cil controlo&#8221;&#46; A investiga&#231;&#227;o cl&#237;nica conduziu &#224; identifica&#231;&#227;o de patologia inflamat&#243;ria cr&#243;nica das vias a&#233;reas superiores de car&#225;cter grave&#44; como factor de agravamento da asma br&#244;nquica&#46; Ap&#243;s terap&#234;utica&#44; que no referido caso implicou abordagem cir&#250;rgica dos seios perinasais&#44; houve melhoria franca do controlo da asma&#46; A prop&#243;sito do caso&#44; &#233; efectuada uma revis&#227;o das principais patologias inflamat&#243;rias al&#233;rgicas das vias a&#233;reas superiores &#40;rinite&#44; sinusite e polipose nasal&#41; e abordadas as suas principais implica&#231;&#245;es no controlo da asma br&#244;nquica&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The authors present a case report of a patient refered to physician for &#8220;difficult-to-treat asthma&#8221;&#46; Clinical evaluation concluded that severe chronic inflammatory upper airway disease was an asthma worsening factor&#46; Patient demonstrated improvement in asthma control&#44; after surgery&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">In the context of the clinical study&#44; the authors present a review of the most common allergic inflammatory diseases of the upper airways &#40;allergic rhinitis&#44; chronic sinusitis and nasal polyposis&#41; and reflect on their impact on asthma&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:38 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Nutku E&#44; Toda M&#44; Hamid Q A&#46; Rhinitis&#44; nasal polyposis and asthma&#58; pathological aspects&#46; <span class="elsevierStyleItalic">In</span> The Nose and Lung Diseases&#46; European Respiratory Monograph&#46; Vol&#46; 6&#46; Monograph 18&#46; 2001&#59; 9&#58;115-32&#46;"
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Global Strategy for Asthma Management and Prevention&#46; National Institutes of Health&#46; National Heart&#44; Lung and Blood Institute&#46; Revised 2005&#46;"
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Allergic Rhinitis and its Impact on Asthma &#40;ARIA&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Bousquet"
                            1 => "P&#46; Van Cauwenberge"
                            2 => "N&#46; Khaltaev"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "2001"
                        "volumen" => "108"
                        "paginaInicial" => "5174"
                        "paginaFinal" => "5334"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Rhinitis and Asthma&#58; One Airway One Disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46; Serrano"
                            1 => "A&#46; Valero"
                            2 => "C&#46; Picado"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2005"
                        "volumen" => "41"
                        "numero" => "10"
                        "paginaInicial" => "569"
                        "paginaFinal" => "578"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16266671"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Perennial Rhinitis&#58; An independent risk factor for asthma in nonatopic subjects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Leynaert B&#233;n&#233;dicte"
                            1 => "Bousquet Jean"
                            2 => "Neukirch Catherine"
                            3 => "Liard Renata"
                            4 => "Neukirch Fran&#231;oise"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1999"
                        "volumen" => "104"
                        "paginaInicial" => "301"
                        "paginaFinal" => "304"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10452748"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Changes in bronchial responsiveness following nasal provocation allergen"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Corren"
                            1 => "A&#46; Adinoff"
                            2 => "C&#46; Irvin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1992"
                        "volumen" => "89"
                        "paginaInicial" => "611"
                        "paginaFinal" => "618"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1740589"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary response to nasal-challenge testing of athopic subject with stable asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Schumaker"
                            1 => "K&#46; Cora"
                            2 => "L&#46; Taussig"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1986"
                        "volumen" => "78"
                        "paginaInicial" => "30"
                        "paginaFinal" => "35"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3722633"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Changes in airway resistance following nasal provocation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "N&#46; Littell"
                            1 => "C&#46; Carlisle"
                            2 => "R&#46; Millman"
                            3 => "S&#46; Braman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm/141.3.580"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am Rev Resp Dis"
                        "fecha" => "1990"
                        "volumen" => "141"
                        "paginaInicial" => "580"
                        "paginaFinal" => "583"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2178523"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Systemic immunologic and inflammatory aspects of allergic rhinitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46; Togias"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "2000"
                        "volumen" => "106"
                        "paginaInicial" => "S247"
                        "paginaFinal" => "S250"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11080739"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sitespecific sensitisation in a murine model of allergic rhinitis&#58; role of the upper airway in lower airway disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; McCusker"
                            1 => "M&#46; Chicoine"
                            2 => "D&#46; Hamid"
                            3 => "B&#46; Mazer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Allergy Clin Immunol"
                        "fecha" => "2002"
                        "volumen" => "110"
                        "paginaInicial" => "891"
                        "paginaFinal" => "898"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12464956"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "G&#46;J&#46; Braunstahl"
                            1 => "S&#46;E&#46; Overbeek"
                            2 => "A&#46; KleinJan"
                            3 => "J&#46;B&#46; Prins"
                            4 => "H&#46;C&#46; Hoogsteden"
                            5 => "W&#46;J&#46; Fokkens"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1067/mai.2001.113046"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "2001"
                        "volumen" => "107"
                        "paginaInicial" => "469"
                        "paginaFinal" => "476"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11240947"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A single nasal allergen challenge increases induced sputum inflammatory markers in nonasthmatic subjects with seasonal allergic rhinitis&#58; correlation with plasma interleukin-5"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "K&#46;M&#46; Beeh"
                            1 => "J&#46; Beier"
                            2 => "O&#46; Kornmann"
                            3 => "C&#46; Meier"
                            4 => "T&#46; Taeumer"
                            5 => "R&#46; Buhl"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Exp Allergy"
                        "fecha" => "2003"
                        "volumen" => "33"
                        "paginaInicial" => "475"
                        "paginaFinal" => "482"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12680863"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Segmental bronchial provocation induces nasal inflammation in allergic rhinitis patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "G&#46;J&#46; Braunstahl"
                            1 => "A&#46; KleinJan"
                            2 => "S&#46;E&#46; Overbeek"
                            3 => "J&#46;B&#46; Prins"
                            4 => "H&#46;C&#46; Hoogsteden"
                            5 => "W&#46;J&#46; Fokkens"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.161.6.9906121"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Resp Crit Care Med"
                        "fecha" => "2000"
                        "volumen" => "161"
                        "paginaInicial" => "2051"
                        "paginaFinal" => "2057"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10852787"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Segmental bronchoprovocation in allergic rhinitis affects mast cell and basophil numbers in nasal and bronchial mucosa"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46;J&#46; Braunstahl"
                            1 => "S&#46;E&#46; Overbeek"
                            2 => "W&#46;J&#46; Fokkens"
                            3 => "A&#46; KleinJan"
                            4 => "A&#46;R&#46; McEuen"
                            5 => "A&#46;F&#46; Walls"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Resp Crit Care Med"
                        "fecha" => "2001"
                        "volumen" => "161"
                        "paginaInicial" => "858"
                        "paginaFinal" => "865"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An update on the asthma &#8211; rhinitis link"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Passalacqua Giovanni"
                            1 => "Ciprandi Giorgio"
                            2 => "Pasquali Mercedes"
                            3 => "Guerra Laura"
                            4 => "Canonica Giogio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Curr Opin Allergy Clin Immunol"
                        "fecha" => "2004"
                        "volumen" => "4"
                        "paginaInicial" => "177"
                        "paginaFinal" => "183"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15126938"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Durham SR&#44; Mackay S&#46; Diseases of the nose&#46; In Respiratory Medicine&#46; Volume 2&#46; Third Edition&#46; 43&#58;1035- -47&#46; Gibson GJ&#44; Geddes DM&#44; Costabel U&#44; Sterk PJ&#44; Corrin B&#44; editors&#46; Saunders&#46;"
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Intranasal corticosteroids versus oral H1 receptor antagonists in allergic rhinitis&#58; systematic review of randomised controlled trials"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "John Weiner"
                            1 => "Michael Abramson"
                            2 => "Puy&#46; Robert"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "1998"
                        "volumen" => "317"
                        "paginaInicial" => "1624"
                        "paginaFinal" => "1629"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9848901"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effect of montelukast on rhinitis symptoms in patients with asthma and seasonal allergic rhinitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "George Philip"
                            1 => "Anjuli&#46;S&#46; Nayak"
                            2 => "Berger William"
                            3 => "Leynadier Francisque"
                            4 => "S&#46; France Vrijens"
                            5 => "Dass Balachandra"
                            6 => "Reiss Theodore"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Curr Med Res"
                        "fecha" => "2004"
                        "volumen" => "20"
                        "numero" => "10"
                        "paginaInicial" => "1549"
                        "paginaFinal" => "1558"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Immunologic changes associated with allergen imunotherapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Stephan Durham"
                            1 => "Till&#46; Stephan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1998"
                        "volumen" => "102"
                        "paginaInicial" => "157"
                        "paginaFinal" => "164"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9723654"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Samantha M&#46; Mucha&#44; Fuad M&#46; Baroody&#46; Sinusitis Update&#46; Curr Opin Allergy Clin Immunol 3&#58;33-38&#46;"
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Adult rhinosinusitis defined"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; Donald"
                            1 => "Lanza"
                            2 => "W&#46; David"
                            3 => "Kennedy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Otoryngol Head Neck Surg"
                        "fecha" => "1997"
                        "volumen" => "117"
                        "paginaInicial" => "S1"
                        "paginaFinal" => "S7"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Carlos Lucas&#46; Asma de dif&#237;cil controlo&#46; In Tratado de Pneumologia&#46; Vol&#46; I&#46; 66&#46;5&#58; 909-920&#46; Gomes MJ&#44; Sotto-Mayor R &#40;eds&#46;&#41;&#46; Sociedade Portuguesa de Pneumologia&#46;"
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Rhinosinusitis in severe asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46; Bresiani"
                            1 => "L&#46; Paradis"
                            2 => "A&#46; Des Roches"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1067/mai.2001.111593"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "2001"
                        "volumen" => "107"
                        "paginaInicial" => "73"
                        "paginaFinal" => "80"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11149994"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nasal endoscopy in asthmatic childr assessment of rhinosinusitis adenoiditis incidence correlations with cytology F microbiology"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Tosca"
                            1 => "A&#46;M&#46; Riccio"
                            2 => "G&#46;L&#46; Marseglia"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Exp Allergy"
                        "fecha" => "2001"
                        "volumen" => "31"
                        "paginaInicial" => "609"
                        "paginaFinal" => "615"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11359430"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chronic sinusitis in severe asthma is related to sputum eosinophilia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46;T&#46; Brinke"
                            1 => "D&#46;C&#46; Grootendorst"
                            2 => "J&#46;T&#46; Schmidt"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "2002"
                        "volumen" => "109"
                        "paginaInicial" => "621"
                        "paginaFinal" => "626"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11941310"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "J&#46; Mensa"
                            1 => "J&#46;M&#46; Gatell"
                            2 => "J&#46;R&#46; Azanza"
                            3 => "A&#46; Dominguez-Gil"
                            4 => "J&#46;E&#46; Garcia"
                            5 => "M&#46;T&#46; Jiminez de Anta"
                            6 => "G&#46; Prats"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Gu&#237;a de Terap&#234;utica Antimicrobiana"
                        "fecha" => "2005"
                        "volumen" => "3"
                        "paginaInicial" => "407"
                        "paginaFinal" => "410"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
              "etiqueta" => "27&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Cori Copilevitz&#44; Raymond Slavin&#46; Sinusitis and asthma&#46; <span class="elsevierStyleItalic">In</span> Current Review of Asthma 2003&#59; 7&#58;61-5&#46; Kaliner MA &#40;ed&#46;&#41;&#46; Current Medicine&#46;"
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib28"
              "etiqueta" => "28&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Intrasinus administration of topical budesonide to allergic patients with chronic sinusitis following surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "F&#46; Lavigne"
                            1 => "L&#46; Cameron"
                            2 => "P&#46;M&#46; Renzi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/00005537-200205000-00015"
                      "Revista" => array:6 [
                        "tituloSerie" => "Laryngoscope"
                        "fecha" => "2002"
                        "volumen" => "112"
                        "paginaInicial" => "858"
                        "paginaFinal" => "864"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12150618"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib29"
              "etiqueta" => "29&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The link between the nose and lung&#44; perennial rhinitis and asthma-is it the same disease&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46;M&#46; Rowe-Jones"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Allergy"
                        "fecha" => "1997"
                        "volumen" => "52"
                        "numero" => "Suppl 36"
                        "paginaInicial" => "20"
                        "paginaFinal" => "28"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12598719"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib30"
              "etiqueta" => "30&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of endoscopic sinus surgery on asthmatic patients with chronic rhinosinusitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "H&#46;-J&#46; Dhong"
                            1 => "Y&#46;S&#46; Jung"
                            2 => "S&#46;K&#46; Chung"
                            3 => "D&#46;C&#46; Choi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Otolaryngol Head Neck Surg"
                        "fecha" => "2001"
                        "volumen" => "124"
                        "paginaInicial" => "99"
                        "paginaFinal" => "104"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11228462"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib31"
              "etiqueta" => "31&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of endoscopic surgery in the management of patients with asthma and chronic sinusitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;N&#46; Palmer"
                            1 => "D&#46;B&#46; Conley"
                            2 => "R&#46;G&#46; Dong"
                            3 => "A&#46;M&#46; Ditto"
                            4 => "P&#46;R&#46; Yamold"
                            5 => "R&#46;C&#46; Kern"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Rhinol"
                        "fecha" => "2001"
                        "volumen" => "15"
                        "numero" => "1"
                        "paginaInicial" => "49"
                        "paginaFinal" => "53"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11258656"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib32"
              "etiqueta" => "32&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effect of endoscopic sinus surgery asthma&#58; management of patients with chronic rhinosinusitis&#44; nasal polyposis&#44; and asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46; Dunlop"
                            1 => "G&#46;K&#46; Scadding"
                            2 => "V&#46;J&#46; Lund"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Rhinol"
                        "fecha" => "1999"
                        "volumen" => "13"
                        "paginaInicial" => "261"
                        "paginaFinal" => "265"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10485011"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib33"
              "etiqueta" => "33&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nasal polyposis&#58; an update"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "Ruby"
                            1 => "Pawanker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cur Opin Allergy Clin Immunol"
                        "fecha" => "2003"
                        "volumen" => "3"
                        "paginaInicial" => "1"
                        "paginaFinal" => "6"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib34"
              "etiqueta" => "34&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pathogenesis of nasal polyps&#58; an update"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46; Pawliczak"
                            1 => "A&#46; Lewandowska-Polak"
                            2 => "M&#46;L&#46; Kowalski"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Curr Allergy Asthma Rep"
                        "fecha" => "2005"
                        "volumen" => "5"
                        "numero" => "6"
                        "paginaInicial" => "463"
                        "paginaFinal" => "471"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16216171"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib35"
              "etiqueta" => "35&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Superantigens and nasal polyps"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46; Bachert"
                            1 => "T&#46; Van Zele"
                            2 => "P&#46; Gevaert"
                            3 => "L&#46; De Schrijver"
                            4 => "P&#46; Van Cauwenberge"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Curr Allergy Asthma Rep"
                        "fecha" => "2003"
                        "volumen" => "3"
                        "numero" => "6"
                        "paginaInicial" => "523"
                        "paginaFinal" => "531"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14531975"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib36"
              "etiqueta" => "36&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nasal polyps"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "Drake-Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Hosp Med"
                        "fecha" => "2004"
                        "volumen" => "65"
                        "numero" => "5"
                        "paginaInicial" => "264"
                        "paginaFinal" => "267"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15176141"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bib37"
              "etiqueta" => "37&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Recorrence rates after endoscopic sinus surgery for massive sinus polyposis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Wynn"
                            1 => "G&#46; Har-El"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/00005537-200405000-00004"
                      "Revista" => array:7 [
                        "tituloSerie" => "Laryngoscope"
                        "fecha" => "2004"
                        "volumen" => "114"
                        "numero" => "5"
                        "paginaInicial" => "811"
                        "paginaFinal" => "813"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15126735"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            37 => array:3 [
              "identificador" => "bib38"
              "etiqueta" => "38&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nasal polypectomy and sinus surgery in patients with asthma and aspirin idiosyncrasy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "G&#46;M&#46; English"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Laryngoscope"
                        "fecha" => "1986"
                        "volumen" => "96"
                        "paginaInicial" => "374"
                        "paginaFinal" => "380"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3959695"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "pt"
  "url" => "/21735115/0000001200000005/v1_201305151428/S2173511506704213/v1_201305151428/pt/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9551"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Review Article&#47;Artigo de Revis&#227;o"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001200000005/v1_201305151428/S2173511506704213/v1_201305151428/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704213?idApp=UINPBA00004E"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Doenças inflamatórias alérgicas das vias aéreas superiores e suas implicações na asma brônquica – A propósito de um caso clínico
Allergic inflammatory diseases of the upper airways and their impact on asthma – Following on from a case report
Ana L. Fonseca1, Ana M. Arrobas2
1 Interna do Complementar de Pneumologia, Serviço de Pneumologia. Director: Dr. Jorge Pires Hospital Geral do Centro Hospitalar de Coimbra Quinta dos Vales Coimbra
2 Assistente Hospitalar Graduada de Pneumologia, Serviço de Pneumologia. Director: Dr. Jorge Pires Hospital Geral do Centro Hospitalar de Coimbra Quinta dos Vales Coimbra
Read
925
Times
was read the article
502
Total PDF
423
Total HTML
Share statistics
 array:24 [
  "pii" => "S2173511506704213"
  "issn" => "21735115"
  "doi" => "10.1016/S2173-5115(06)70421-3"
  "estado" => "S300"
  "fechaPublicacion" => "2006-09-01"
  "aid" => "70421"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2006"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "rev"
  "cita" => "Rev Port Pneumol. 2006;12:563-79"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3479
    "formatos" => array:3 [
      "EPUB" => 235
      "HTML" => 1768
      "PDF" => 1476
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173511506704225"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70422-5"
    "estado" => "S300"
    "fechaPublicacion" => "2006-09-01"
    "aid" => "70422"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "rev"
    "cita" => "Rev Port Pneumol. 2006;12:581-601"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4320
      "formatos" => array:3 [
        "EPUB" => 219
        "HTML" => 1660
        "PDF" => 2441
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Pneumonias intersticiais idiop&#225;ticas &#8211; Uma revis&#227;o da literatura"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "581"
          "paginaFinal" => "601"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Interstitial idiopathic pneumonias &#8211; A literature review"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Paulo Jos&#233; de Lima Mota"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "Paulo Jos&#233;"
              "apellidos" => "de Lima Mota"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704225?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000005/v1_201305151428/S2173511506704225/v1_201305151428/pt/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173511506704201"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70420-1"
    "estado" => "S300"
    "fechaPublicacion" => "2006-09-01"
    "aid" => "70420"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "rev"
    "cita" => "Rev Port Pneumol. 2006;12:545-61"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2755
      "formatos" => array:3 [
        "EPUB" => 232
        "HTML" => 1651
        "PDF" => 872
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Cancro do pulm&#227;o na mulher&#58; Uma entidade diferente&#63;"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "545"
          "paginaFinal" => "561"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Lung cancer in women&#58; A different entity&#63;"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Renato Sotto-Mayor"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "Renato"
              "apellidos" => "Sotto-Mayor"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704201?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000005/v1_201305151428/S2173511506704201/v1_201305151428/pt/main.assets"
  ]
  "pt" => array:14 [
    "idiomaDefecto" => true
    "titulo" => "Doen&#231;as inflamat&#243;rias al&#233;rgicas das vias a&#233;reas superiores e suas implica&#231;&#245;es na asma br&#244;nquica &#8211; A prop&#243;sito de um caso cl&#237;nico"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "563"
        "paginaFinal" => "579"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Ana L&#46; Fonseca, Ana M&#46; Arrobas"
        "autores" => array:2 [
          0 => array:3 [
            "nombre" => "Ana L&#46;"
            "apellidos" => "Fonseca"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Ana M&#46;"
            "apellidos" => "Arrobas"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">2</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Interna do Complementar de Pneumologia&#44; Servi&#231;o de Pneumologia&#46; Director&#58; Dr&#46; Jorge Pires Hospital Geral do Centro Hospitalar de Coimbra Quinta dos Vales Coimbra"
            "etiqueta" => "<span class="elsevierStyleSup">1</span>"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Assistente Hospitalar Graduada de Pneumologia&#44; Servi&#231;o de Pneumologia&#46; Director&#58; Dr&#46; Jorge Pires Hospital Geral do Centro Hospitalar de Coimbra Quinta dos Vales Coimbra"
            "etiqueta" => "<span class="elsevierStyleSup">2</span>"
            "identificador" => "aff0010"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Allergic inflammatory diseases of the upper airways and their impact on asthma &#8211; Following on from a case report"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2006-02-02"
    "fechaAceptado" => "2006-05-18"
    "PalabrasClave" => array:2 [
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec158865"
          "palabras" => array:4 [
            0 => "Asma br&#244;nquica"
            1 => "rinite al&#233;rgica"
            2 => "sinusite cr&#243;nica"
            3 => "polipose nasal"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key-words"
          "identificador" => "xpalclavsec158864"
          "palabras" => array:4 [
            0 => "Asthma"
            1 => "allergic rhinitis"
            2 => "chronic sinusitis"
            3 => "nasal polyposis"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "pt" => array:2 [
        "titulo" => "Resumo"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Os autores apresentam o caso cl&#237;nico de uma doente referenciada &#224; consulta de alergologia respirat&#243;ria por &#8220;asma de dif&#237;cil controlo&#8221;&#46; A investiga&#231;&#227;o cl&#237;nica conduziu &#224; identifica&#231;&#227;o de patologia inflamat&#243;ria cr&#243;nica das vias a&#233;reas superiores de car&#225;cter grave&#44; como factor de agravamento da asma br&#244;nquica&#46; Ap&#243;s terap&#234;utica&#44; que no referido caso implicou abordagem cir&#250;rgica dos seios perinasais&#44; houve melhoria franca do controlo da asma&#46; A prop&#243;sito do caso&#44; &#233; efectuada uma revis&#227;o das principais patologias inflamat&#243;rias al&#233;rgicas das vias a&#233;reas superiores &#40;rinite&#44; sinusite e polipose nasal&#41; e abordadas as suas principais implica&#231;&#245;es no controlo da asma br&#244;nquica&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The authors present a case report of a patient refered to physician for &#8220;difficult-to-treat asthma&#8221;&#46; Clinical evaluation concluded that severe chronic inflammatory upper airway disease was an asthma worsening factor&#46; Patient demonstrated improvement in asthma control&#44; after surgery&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">In the context of the clinical study&#44; the authors present a review of the most common allergic inflammatory diseases of the upper airways &#40;allergic rhinitis&#44; chronic sinusitis and nasal polyposis&#41; and reflect on their impact on asthma&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:38 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Nutku E&#44; Toda M&#44; Hamid Q A&#46; Rhinitis&#44; nasal polyposis and asthma&#58; pathological aspects&#46; <span class="elsevierStyleItalic">In</span> The Nose and Lung Diseases&#46; European Respiratory Monograph&#46; Vol&#46; 6&#46; Monograph 18&#46; 2001&#59; 9&#58;115-32&#46;"
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Global Strategy for Asthma Management and Prevention&#46; National Institutes of Health&#46; National Heart&#44; Lung and Blood Institute&#46; Revised 2005&#46;"
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Allergic Rhinitis and its Impact on Asthma &#40;ARIA&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Bousquet"
                            1 => "P&#46; Van Cauwenberge"
                            2 => "N&#46; Khaltaev"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "2001"
                        "volumen" => "108"
                        "paginaInicial" => "5174"
                        "paginaFinal" => "5334"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Rhinitis and Asthma&#58; One Airway One Disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46; Serrano"
                            1 => "A&#46; Valero"
                            2 => "C&#46; Picado"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2005"
                        "volumen" => "41"
                        "numero" => "10"
                        "paginaInicial" => "569"
                        "paginaFinal" => "578"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16266671"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Perennial Rhinitis&#58; An independent risk factor for asthma in nonatopic subjects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Leynaert B&#233;n&#233;dicte"
                            1 => "Bousquet Jean"
                            2 => "Neukirch Catherine"
                            3 => "Liard Renata"
                            4 => "Neukirch Fran&#231;oise"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1999"
                        "volumen" => "104"
                        "paginaInicial" => "301"
                        "paginaFinal" => "304"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10452748"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Changes in bronchial responsiveness following nasal provocation allergen"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Corren"
                            1 => "A&#46; Adinoff"
                            2 => "C&#46; Irvin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1992"
                        "volumen" => "89"
                        "paginaInicial" => "611"
                        "paginaFinal" => "618"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1740589"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary response to nasal-challenge testing of athopic subject with stable asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Schumaker"
                            1 => "K&#46; Cora"
                            2 => "L&#46; Taussig"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1986"
                        "volumen" => "78"
                        "paginaInicial" => "30"
                        "paginaFinal" => "35"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3722633"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Changes in airway resistance following nasal provocation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "N&#46; Littell"
                            1 => "C&#46; Carlisle"
                            2 => "R&#46; Millman"
                            3 => "S&#46; Braman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm/141.3.580"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am Rev Resp Dis"
                        "fecha" => "1990"
                        "volumen" => "141"
                        "paginaInicial" => "580"
                        "paginaFinal" => "583"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2178523"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Systemic immunologic and inflammatory aspects of allergic rhinitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46; Togias"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "2000"
                        "volumen" => "106"
                        "paginaInicial" => "S247"
                        "paginaFinal" => "S250"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11080739"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sitespecific sensitisation in a murine model of allergic rhinitis&#58; role of the upper airway in lower airway disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; McCusker"
                            1 => "M&#46; Chicoine"
                            2 => "D&#46; Hamid"
                            3 => "B&#46; Mazer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J&#46; Allergy Clin Immunol"
                        "fecha" => "2002"
                        "volumen" => "110"
                        "paginaInicial" => "891"
                        "paginaFinal" => "898"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12464956"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "G&#46;J&#46; Braunstahl"
                            1 => "S&#46;E&#46; Overbeek"
                            2 => "A&#46; KleinJan"
                            3 => "J&#46;B&#46; Prins"
                            4 => "H&#46;C&#46; Hoogsteden"
                            5 => "W&#46;J&#46; Fokkens"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1067/mai.2001.113046"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "2001"
                        "volumen" => "107"
                        "paginaInicial" => "469"
                        "paginaFinal" => "476"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11240947"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A single nasal allergen challenge increases induced sputum inflammatory markers in nonasthmatic subjects with seasonal allergic rhinitis&#58; correlation with plasma interleukin-5"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "K&#46;M&#46; Beeh"
                            1 => "J&#46; Beier"
                            2 => "O&#46; Kornmann"
                            3 => "C&#46; Meier"
                            4 => "T&#46; Taeumer"
                            5 => "R&#46; Buhl"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Exp Allergy"
                        "fecha" => "2003"
                        "volumen" => "33"
                        "paginaInicial" => "475"
                        "paginaFinal" => "482"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12680863"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Segmental bronchial provocation induces nasal inflammation in allergic rhinitis patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "G&#46;J&#46; Braunstahl"
                            1 => "A&#46; KleinJan"
                            2 => "S&#46;E&#46; Overbeek"
                            3 => "J&#46;B&#46; Prins"
                            4 => "H&#46;C&#46; Hoogsteden"
                            5 => "W&#46;J&#46; Fokkens"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.161.6.9906121"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Resp Crit Care Med"
                        "fecha" => "2000"
                        "volumen" => "161"
                        "paginaInicial" => "2051"
                        "paginaFinal" => "2057"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10852787"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Segmental bronchoprovocation in allergic rhinitis affects mast cell and basophil numbers in nasal and bronchial mucosa"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46;J&#46; Braunstahl"
                            1 => "S&#46;E&#46; Overbeek"
                            2 => "W&#46;J&#46; Fokkens"
                            3 => "A&#46; KleinJan"
                            4 => "A&#46;R&#46; McEuen"
                            5 => "A&#46;F&#46; Walls"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Resp Crit Care Med"
                        "fecha" => "2001"
                        "volumen" => "161"
                        "paginaInicial" => "858"
                        "paginaFinal" => "865"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An update on the asthma &#8211; rhinitis link"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Passalacqua Giovanni"
                            1 => "Ciprandi Giorgio"
                            2 => "Pasquali Mercedes"
                            3 => "Guerra Laura"
                            4 => "Canonica Giogio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Curr Opin Allergy Clin Immunol"
                        "fecha" => "2004"
                        "volumen" => "4"
                        "paginaInicial" => "177"
                        "paginaFinal" => "183"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15126938"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Durham SR&#44; Mackay S&#46; Diseases of the nose&#46; In Respiratory Medicine&#46; Volume 2&#46; Third Edition&#46; 43&#58;1035- -47&#46; Gibson GJ&#44; Geddes DM&#44; Costabel U&#44; Sterk PJ&#44; Corrin B&#44; editors&#46; Saunders&#46;"
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Intranasal corticosteroids versus oral H1 receptor antagonists in allergic rhinitis&#58; systematic review of randomised controlled trials"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "John Weiner"
                            1 => "Michael Abramson"
                            2 => "Puy&#46; Robert"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "1998"
                        "volumen" => "317"
                        "paginaInicial" => "1624"
                        "paginaFinal" => "1629"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9848901"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effect of montelukast on rhinitis symptoms in patients with asthma and seasonal allergic rhinitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "George Philip"
                            1 => "Anjuli&#46;S&#46; Nayak"
                            2 => "Berger William"
                            3 => "Leynadier Francisque"
                            4 => "S&#46; France Vrijens"
                            5 => "Dass Balachandra"
                            6 => "Reiss Theodore"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Curr Med Res"
                        "fecha" => "2004"
                        "volumen" => "20"
                        "numero" => "10"
                        "paginaInicial" => "1549"
                        "paginaFinal" => "1558"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Immunologic changes associated with allergen imunotherapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Stephan Durham"
                            1 => "Till&#46; Stephan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1998"
                        "volumen" => "102"
                        "paginaInicial" => "157"
                        "paginaFinal" => "164"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9723654"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Samantha M&#46; Mucha&#44; Fuad M&#46; Baroody&#46; Sinusitis Update&#46; Curr Opin Allergy Clin Immunol 3&#58;33-38&#46;"
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Adult rhinosinusitis defined"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; Donald"
                            1 => "Lanza"
                            2 => "W&#46; David"
                            3 => "Kennedy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Otoryngol Head Neck Surg"
                        "fecha" => "1997"
                        "volumen" => "117"
                        "paginaInicial" => "S1"
                        "paginaFinal" => "S7"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Carlos Lucas&#46; Asma de dif&#237;cil controlo&#46; In Tratado de Pneumologia&#46; Vol&#46; I&#46; 66&#46;5&#58; 909-920&#46; Gomes MJ&#44; Sotto-Mayor R &#40;eds&#46;&#41;&#46; Sociedade Portuguesa de Pneumologia&#46;"
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Rhinosinusitis in severe asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46; Bresiani"
                            1 => "L&#46; Paradis"
                            2 => "A&#46; Des Roches"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1067/mai.2001.111593"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "2001"
                        "volumen" => "107"
                        "paginaInicial" => "73"
                        "paginaFinal" => "80"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11149994"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nasal endoscopy in asthmatic childr assessment of rhinosinusitis adenoiditis incidence correlations with cytology F microbiology"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Tosca"
                            1 => "A&#46;M&#46; Riccio"
                            2 => "G&#46;L&#46; Marseglia"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Exp Allergy"
                        "fecha" => "2001"
                        "volumen" => "31"
                        "paginaInicial" => "609"
                        "paginaFinal" => "615"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11359430"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chronic sinusitis in severe asthma is related to sputum eosinophilia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46;T&#46; Brinke"
                            1 => "D&#46;C&#46; Grootendorst"
                            2 => "J&#46;T&#46; Schmidt"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "2002"
                        "volumen" => "109"
                        "paginaInicial" => "621"
                        "paginaFinal" => "626"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11941310"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "J&#46; Mensa"
                            1 => "J&#46;M&#46; Gatell"
                            2 => "J&#46;R&#46; Azanza"
                            3 => "A&#46; Dominguez-Gil"
                            4 => "J&#46;E&#46; Garcia"
                            5 => "M&#46;T&#46; Jiminez de Anta"
                            6 => "G&#46; Prats"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Gu&#237;a de Terap&#234;utica Antimicrobiana"
                        "fecha" => "2005"
                        "volumen" => "3"
                        "paginaInicial" => "407"
                        "paginaFinal" => "410"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
              "etiqueta" => "27&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Cori Copilevitz&#44; Raymond Slavin&#46; Sinusitis and asthma&#46; <span class="elsevierStyleItalic">In</span> Current Review of Asthma 2003&#59; 7&#58;61-5&#46; Kaliner MA &#40;ed&#46;&#41;&#46; Current Medicine&#46;"
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib28"
              "etiqueta" => "28&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Intrasinus administration of topical budesonide to allergic patients with chronic sinusitis following surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "F&#46; Lavigne"
                            1 => "L&#46; Cameron"
                            2 => "P&#46;M&#46; Renzi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/00005537-200205000-00015"
                      "Revista" => array:6 [
                        "tituloSerie" => "Laryngoscope"
                        "fecha" => "2002"
                        "volumen" => "112"
                        "paginaInicial" => "858"
                        "paginaFinal" => "864"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12150618"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib29"
              "etiqueta" => "29&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The link between the nose and lung&#44; perennial rhinitis and asthma-is it the same disease&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46;M&#46; Rowe-Jones"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Allergy"
                        "fecha" => "1997"
                        "volumen" => "52"
                        "numero" => "Suppl 36"
                        "paginaInicial" => "20"
                        "paginaFinal" => "28"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12598719"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib30"
              "etiqueta" => "30&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of endoscopic sinus surgery on asthmatic patients with chronic rhinosinusitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "H&#46;-J&#46; Dhong"
                            1 => "Y&#46;S&#46; Jung"
                            2 => "S&#46;K&#46; Chung"
                            3 => "D&#46;C&#46; Choi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Otolaryngol Head Neck Surg"
                        "fecha" => "2001"
                        "volumen" => "124"
                        "paginaInicial" => "99"
                        "paginaFinal" => "104"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11228462"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib31"
              "etiqueta" => "31&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of endoscopic surgery in the management of patients with asthma and chronic sinusitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;N&#46; Palmer"
                            1 => "D&#46;B&#46; Conley"
                            2 => "R&#46;G&#46; Dong"
                            3 => "A&#46;M&#46; Ditto"
                            4 => "P&#46;R&#46; Yamold"
                            5 => "R&#46;C&#46; Kern"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Rhinol"
                        "fecha" => "2001"
                        "volumen" => "15"
                        "numero" => "1"
                        "paginaInicial" => "49"
                        "paginaFinal" => "53"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11258656"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib32"
              "etiqueta" => "32&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effect of endoscopic sinus surgery asthma&#58; management of patients with chronic rhinosinusitis&#44; nasal polyposis&#44; and asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46; Dunlop"
                            1 => "G&#46;K&#46; Scadding"
                            2 => "V&#46;J&#46; Lund"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Rhinol"
                        "fecha" => "1999"
                        "volumen" => "13"
                        "paginaInicial" => "261"
                        "paginaFinal" => "265"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10485011"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib33"
              "etiqueta" => "33&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nasal polyposis&#58; an update"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "Ruby"
                            1 => "Pawanker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cur Opin Allergy Clin Immunol"
                        "fecha" => "2003"
                        "volumen" => "3"
                        "paginaInicial" => "1"
                        "paginaFinal" => "6"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib34"
              "etiqueta" => "34&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pathogenesis of nasal polyps&#58; an update"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46; Pawliczak"
                            1 => "A&#46; Lewandowska-Polak"
                            2 => "M&#46;L&#46; Kowalski"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Curr Allergy Asthma Rep"
                        "fecha" => "2005"
                        "volumen" => "5"
                        "numero" => "6"
                        "paginaInicial" => "463"
                        "paginaFinal" => "471"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16216171"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib35"
              "etiqueta" => "35&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Superantigens and nasal polyps"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46; Bachert"
                            1 => "T&#46; Van Zele"
                            2 => "P&#46; Gevaert"
                            3 => "L&#46; De Schrijver"
                            4 => "P&#46; Van Cauwenberge"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Curr Allergy Asthma Rep"
                        "fecha" => "2003"
                        "volumen" => "3"
                        "numero" => "6"
                        "paginaInicial" => "523"
                        "paginaFinal" => "531"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14531975"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib36"
              "etiqueta" => "36&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nasal polyps"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "Drake-Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Hosp Med"
                        "fecha" => "2004"
                        "volumen" => "65"
                        "numero" => "5"
                        "paginaInicial" => "264"
                        "paginaFinal" => "267"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15176141"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bib37"
              "etiqueta" => "37&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Recorrence rates after endoscopic sinus surgery for massive sinus polyposis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Wynn"
                            1 => "G&#46; Har-El"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/00005537-200405000-00004"
                      "Revista" => array:7 [
                        "tituloSerie" => "Laryngoscope"
                        "fecha" => "2004"
                        "volumen" => "114"
                        "numero" => "5"
                        "paginaInicial" => "811"
                        "paginaFinal" => "813"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15126735"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            37 => array:3 [
              "identificador" => "bib38"
              "etiqueta" => "38&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nasal polypectomy and sinus surgery in patients with asthma and aspirin idiosyncrasy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "G&#46;M&#46; English"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Laryngoscope"
                        "fecha" => "1986"
                        "volumen" => "96"
                        "paginaInicial" => "374"
                        "paginaFinal" => "380"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3959695"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "pt"
  "url" => "/21735115/0000001200000005/v1_201305151428/S2173511506704213/v1_201305151428/pt/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9551"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Review Article&#47;Artigo de Revis&#227;o"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001200000005/v1_201305151428/S2173511506704213/v1_201305151428/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704213?idApp=UINPBA00004E"
]
Article information
ISSN: 21735115
Original language: Portuguese
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 5 2 7
2024 October 29 22 51
2024 September 26 24 50
2024 August 42 33 75
2024 July 34 30 64
2024 June 21 20 41
2024 May 25 35 60
2024 April 20 23 43
2024 March 22 38 60
2024 February 24 28 52
2024 January 13 14 27
2023 December 23 21 44
2023 November 18 23 41
2023 October 16 31 47
2023 September 21 30 51
2023 August 19 25 44
2023 July 16 38 54
2023 June 19 19 38
2023 May 17 35 52
2023 April 13 11 24
Show all

Follow this link to access the full text of the article

Pulmonology

Are you a health professional able to prescribe or dispense drugs?