array:24 [
  "pii" => "S2173511506704304"
  "issn" => "21735115"
  "doi" => "10.1016/S2173-5115(06)70430-4"
  "estado" => "S300"
  "fechaPublicacion" => "2006-11-01"
  "aid" => "70430"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2006"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "rev"
  "cita" => "Rev Port Pneumol. 2006;12:709-14"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 5029
    "formatos" => array:3 [
      "EPUB" => 229
      "HTML" => 2197
      "PDF" => 2603
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173511506704316"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70431-6"
    "estado" => "S300"
    "fechaPublicacion" => "2006-11-01"
    "aid" => "70431"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Pneumol. 2006;12:715-24"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4244
      "formatos" => array:3 [
        "EPUB" => 220
        "HTML" => 2925
        "PDF" => 1099
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Toxicidade pulmonar induzida pela rapamicina"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "715"
          "paginaFinal" => "724"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Lung toxicity induced by rapamycin"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "C. Damas, A. Oliveira, A. Morais, J. Agostinho Marques"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "C."
              "apellidos" => "Damas"
            ]
            1 => array:2 [
              "nombre" => "A."
              "apellidos" => "Oliveira"
            ]
            2 => array:2 [
              "nombre" => "A."
              "apellidos" => "Morais"
            ]
            3 => array:2 [
              "nombre" => "J."
              "apellidos" => "Agostinho Marques"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704316?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000006/v1_201305151431/S2173511506704316/v1_201305151431/pt/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173511506704298"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70429-8"
    "estado" => "S300"
    "fechaPublicacion" => "2006-11-01"
    "aid" => "70429"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "rev"
    "cita" => "Rev Port Pneumol. 2006;12:683-708"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3269
      "formatos" => array:3 [
        "EPUB" => 234
        "HTML" => 1890
        "PDF" => 1145
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Os factores genéticos da asma"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "683"
          "paginaFinal" => "708"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Asthma genetic factors"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Paula Alexandra Videira, Luís Miguel Borrego, Hélder Trindade"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "Paula"
              "apellidos" => "Alexandra Videira"
            ]
            1 => array:2 [
              "nombre" => "Luís"
              "apellidos" => "Miguel Borrego"
            ]
            2 => array:2 [
              "nombre" => "Hélder"
              "apellidos" => "Trindade"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704298?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000006/v1_201305151431/S2173511506704298/v1_201305151431/pt/main.assets"
  ]
  "pt" => array:14 [
    "idiomaDefecto" => true
    "titulo" => "Asma, polipose nasal e intolerância à aspirina – Uma tríade a recordar"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "709"
        "paginaFinal" => "714"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Bárbara Seabra, Raquel Duarte, Raul César Sá"
        "autores" => array:3 [
          0 => array:3 [
            "nombre" => "Bárbara"
            "apellidos" => "Seabra"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">4</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Raquel"
            "apellidos" => "Duarte"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">2</span>"
                "identificador" => "aff0010"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">4</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Raul"
            "apellidos" => "C&#233;sar S&#225;"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">3</span>"
                "identificador" => "aff0015"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">4</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:4 [
          0 => array:3 [
            "entidad" => "Interna Complementar de Pneumologia"
            "etiqueta" => "<span class="elsevierStyleSup">1</span>"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Assistente Hospitalar de Pneumologia"
            "etiqueta" => "<span class="elsevierStyleSup">2</span>"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Director do Servi&#231;o de Pneumologia"
            "etiqueta" => "<span class="elsevierStyleSup">3</span>"
            "identificador" => "aff0015"
          ]
          3 => array:3 [
            "entidad" => "Centro Hospitalar Vila Nova de Gaia&#44; Servi&#231;o de Pneumologia&#44; Rua Concei&#231;&#227;o Fernandes&#44; 4434-502 V&#46; N&#46; Gaia"
            "etiqueta" => "<span class="elsevierStyleSup">4</span>"
            "identificador" => "aff0020"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Asthma&#44; nasal polyposis and aspirin intolerance &#8211; A triad to remember"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2006-03-03"
    "fechaAceptado" => "2006-06-30"
    "PalabrasClave" => array:2 [
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec158926"
          "palabras" => array:4 [
            0 => "Asma"
            1 => "polipose nasal"
            2 => "intoler&#226;ncia aspirina"
            3 => "s&#237;ndroma de Widal"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec158925"
          "palabras" => array:4 [
            0 => "Asthma"
            1 => "nasal polyposis"
            2 => "aspirin intolerance"
            3 => "Widal syndrome"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "pt" => array:2 [
        "titulo" => "Resumo"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Apesar de reconhecida h&#225; mais de meio s&#233;culo&#44; a tr&#237;ade constitu&#237;da por asma severa&#44; polipose nasal e intoler&#226;ncia ao &#225;cido acetilsalic&#237;lico a denominada <span class="elsevierStyleItalic">asma induzida pela aspirina</span> ou <span class="elsevierStyleItalic">sindrome de Widal</span> permanece francamente subdiagnosticada e insuficientemente tratada&#46; De entre as principais raz&#245;es para esta situa&#231;&#227;o destacam-se o desconhecimento das suas caracter&#237;sticas cl&#237;nicas&#44; a fisiopatologia e&#44; por vezes&#44; at&#233; a pr&#243;pria exist&#234;ncia desta entidade&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">O presente artigo pretende alertar a popula&#231;&#227;o m&#233;dica para esta s&#237;ndroma&#44; para as suas particularidades e para os cuidados espec&#237;ficos no seu tratamento&#44; com vista a uma melhoria na presta&#231;&#227;o dos cuidados de sa&#250;de&#58; O diagn&#243;stico correcto &#233; o primeiro passo no tratamento eficaz de qualquer patologia&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Despite more than a half-century of recognition&#44; the triad characterised by severe asthma&#44; nasal polyposis and acetylsalicylic acid intolerance known as <span class="elsevierStyleItalic">aspirin induced asthma</span> or <span class="elsevierStyleItalic">Widal&#39;s triad</span> remains markedly underdiagnosed and mistreated&#46; A number of reasons may contribute to this situation with the lack of awareness of its clinical characteristics&#44; pathophysiology and even sometimes of its&#8217; actual existence the main ones&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">This review article aims to alert physicians to this entity and its particularities in an attempt to improve healthcare&#46; A correct diagnosis is the first step in the effective treatment of a disease&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:7 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;F&#46; Widal"
                            1 => "P&#46; Abrami"
                            2 => "J&#46; Lermoyez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1922"
                        "editorial" => "La Presse M&#233;dicale"
                        "editorialLocalizacion" => "Paris"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diagnosis&#44; Prevention and Treatment of Aspirin-Induced Asthma and Rhinitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "G&#46; Bochenek"
                            1 => "K&#46; Banska"
                            2 => "Z&#46; Szabo"
                            3 => "E&#46; Nizankowska"
                            4 => "A&#46; Szczeklik"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Current Drug Targets &#8211; Inflammation &#38;Allergy"
                        "fecha" => "2002"
                        "numero" => "1"
                        "paginaInicial" => "1"
                        "paginaFinal" => "11"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25772178"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cross sensitivity with acetaminophen in aspirin-sensitive subjects with asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;A&#46; Settipane"
                            1 => "D&#46;D&#46; Stevenson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clinical Immunology"
                        "fecha" => "1989"
                        "volumen" => "84"
                        "numero" => "1"
                        "paginaInicial" => "26"
                        "paginaFinal" => "33"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Aspirin and Asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "K&#46;S&#46; Babu"
                            1 => "S&#46;S&#46; Salvi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2000"
                        "volumen" => "118"
                        "paginaInicial" => "1470"
                        "paginaFinal" => "1476"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11083703"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin intolerant asthmatics"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "B&#46; Dahlen"
                            1 => "E&#46; Nizankowska"
                            2 => "A&#46; Szczeliik"
                            3 => "G&#46; Bochenek"
                            4 => "M&#46; Kumlin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Respiratory Care Med"
                        "fecha" => "1998"
                        "volumen" => "157"
                        "paginaInicial" => "11887"
                        "paginaFinal" => "11896"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The pivotal role of lipoxigenase products in the reaction of aspirin sensitive asthmatics to aspirin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46; Israel"
                            1 => "E&#46;R&#46; Fisher"
                            2 => "M&#46;A&#46; Rosenberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm/148.6_Pt_1.1447"
                      "Revista" => array:5 [
                        "tituloSerie" => "Am Rev Respiratory Dis"
                        "fecha" => "1993"
                        "volumen" => "148"
                        "paginaInicial" => "1447"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8256883"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long term effects of asthma desensitization &#8211; treatment of aspirin induced rhinosinusitis-asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;M&#46; Sweet"
                            1 => "D&#46;D&#46; Stevenson"
                            2 => "D&#46;A&#46; Mathison"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "J Clin Immunol"
                        "fecha" => "1990"
                        "volumen" => "85"
                        "paginaInicial" => "59"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "pt"
  "url" => "/21735115/0000001200000006/v1_201305151431/S2173511506704304/v1_201305151431/pt/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9551"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Review Article&#47;Artigo de Revis&#227;o"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001200000006/v1_201305151431/S2173511506704304/v1_201305151431/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704304?idApp=UINPBA00004E"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Asma, polipose nasal e intolerância à aspirina – Uma tríade a recordar
Asthma, nasal polyposis and aspirin intolerance – A triad to remember
Bárbara Seabra1,4, Raquel Duarte2,4, Raul César Sá3,4
1 Interna Complementar de Pneumologia
2 Assistente Hospitalar de Pneumologia
3 Director do Serviço de Pneumologia
4 Centro Hospitalar Vila Nova de Gaia, Serviço de Pneumologia, Rua Conceição Fernandes, 4434-502 V. N. Gaia
Read
954
Times
was read the article
490
Total PDF
464
Total HTML
Share statistics
 array:24 [
  "pii" => "S2173511506704304"
  "issn" => "21735115"
  "doi" => "10.1016/S2173-5115(06)70430-4"
  "estado" => "S300"
  "fechaPublicacion" => "2006-11-01"
  "aid" => "70430"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2006"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "rev"
  "cita" => "Rev Port Pneumol. 2006;12:709-14"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 5029
    "formatos" => array:3 [
      "EPUB" => 229
      "HTML" => 2197
      "PDF" => 2603
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173511506704316"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70431-6"
    "estado" => "S300"
    "fechaPublicacion" => "2006-11-01"
    "aid" => "70431"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Pneumol. 2006;12:715-24"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4244
      "formatos" => array:3 [
        "EPUB" => 220
        "HTML" => 2925
        "PDF" => 1099
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Toxicidade pulmonar induzida pela rapamicina"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "715"
          "paginaFinal" => "724"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Lung toxicity induced by rapamycin"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "C&#46; Damas, A&#46; Oliveira, A&#46; Morais, J&#46; Agostinho Marques"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Damas"
            ]
            1 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Oliveira"
            ]
            2 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Morais"
            ]
            3 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Agostinho Marques"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704316?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000006/v1_201305151431/S2173511506704316/v1_201305151431/pt/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173511506704298"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70429-8"
    "estado" => "S300"
    "fechaPublicacion" => "2006-11-01"
    "aid" => "70429"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "rev"
    "cita" => "Rev Port Pneumol. 2006;12:683-708"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3269
      "formatos" => array:3 [
        "EPUB" => 234
        "HTML" => 1890
        "PDF" => 1145
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Os factores gen&#233;ticos da asma"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "683"
          "paginaFinal" => "708"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Asthma genetic factors"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Paula Alexandra Videira, Lu&#237;s Miguel Borrego, H&#233;lder Trindade"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "Paula"
              "apellidos" => "Alexandra Videira"
            ]
            1 => array:2 [
              "nombre" => "Lu&#237;s"
              "apellidos" => "Miguel Borrego"
            ]
            2 => array:2 [
              "nombre" => "H&#233;lder"
              "apellidos" => "Trindade"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704298?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000006/v1_201305151431/S2173511506704298/v1_201305151431/pt/main.assets"
  ]
  "pt" => array:14 [
    "idiomaDefecto" => true
    "titulo" => "Asma&#44; polipose nasal e intoler&#226;ncia &#224; aspirina &#8211; Uma tr&#237;ade a recordar"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "709"
        "paginaFinal" => "714"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "B&#225;rbara Seabra, Raquel Duarte, Raul C&#233;sar S&#225;"
        "autores" => array:3 [
          0 => array:3 [
            "nombre" => "B&#225;rbara"
            "apellidos" => "Seabra"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">4</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Raquel"
            "apellidos" => "Duarte"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">2</span>"
                "identificador" => "aff0010"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">4</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Raul"
            "apellidos" => "C&#233;sar S&#225;"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">3</span>"
                "identificador" => "aff0015"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">4</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:4 [
          0 => array:3 [
            "entidad" => "Interna Complementar de Pneumologia"
            "etiqueta" => "<span class="elsevierStyleSup">1</span>"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Assistente Hospitalar de Pneumologia"
            "etiqueta" => "<span class="elsevierStyleSup">2</span>"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Director do Servi&#231;o de Pneumologia"
            "etiqueta" => "<span class="elsevierStyleSup">3</span>"
            "identificador" => "aff0015"
          ]
          3 => array:3 [
            "entidad" => "Centro Hospitalar Vila Nova de Gaia&#44; Servi&#231;o de Pneumologia&#44; Rua Concei&#231;&#227;o Fernandes&#44; 4434-502 V&#46; N&#46; Gaia"
            "etiqueta" => "<span class="elsevierStyleSup">4</span>"
            "identificador" => "aff0020"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Asthma&#44; nasal polyposis and aspirin intolerance &#8211; A triad to remember"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2006-03-03"
    "fechaAceptado" => "2006-06-30"
    "PalabrasClave" => array:2 [
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec158926"
          "palabras" => array:4 [
            0 => "Asma"
            1 => "polipose nasal"
            2 => "intoler&#226;ncia aspirina"
            3 => "s&#237;ndroma de Widal"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec158925"
          "palabras" => array:4 [
            0 => "Asthma"
            1 => "nasal polyposis"
            2 => "aspirin intolerance"
            3 => "Widal syndrome"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "pt" => array:2 [
        "titulo" => "Resumo"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Apesar de reconhecida h&#225; mais de meio s&#233;culo&#44; a tr&#237;ade constitu&#237;da por asma severa&#44; polipose nasal e intoler&#226;ncia ao &#225;cido acetilsalic&#237;lico a denominada <span class="elsevierStyleItalic">asma induzida pela aspirina</span> ou <span class="elsevierStyleItalic">sindrome de Widal</span> permanece francamente subdiagnosticada e insuficientemente tratada&#46; De entre as principais raz&#245;es para esta situa&#231;&#227;o destacam-se o desconhecimento das suas caracter&#237;sticas cl&#237;nicas&#44; a fisiopatologia e&#44; por vezes&#44; at&#233; a pr&#243;pria exist&#234;ncia desta entidade&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">O presente artigo pretende alertar a popula&#231;&#227;o m&#233;dica para esta s&#237;ndroma&#44; para as suas particularidades e para os cuidados espec&#237;ficos no seu tratamento&#44; com vista a uma melhoria na presta&#231;&#227;o dos cuidados de sa&#250;de&#58; O diagn&#243;stico correcto &#233; o primeiro passo no tratamento eficaz de qualquer patologia&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Despite more than a half-century of recognition&#44; the triad characterised by severe asthma&#44; nasal polyposis and acetylsalicylic acid intolerance known as <span class="elsevierStyleItalic">aspirin induced asthma</span> or <span class="elsevierStyleItalic">Widal&#39;s triad</span> remains markedly underdiagnosed and mistreated&#46; A number of reasons may contribute to this situation with the lack of awareness of its clinical characteristics&#44; pathophysiology and even sometimes of its&#8217; actual existence the main ones&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">This review article aims to alert physicians to this entity and its particularities in an attempt to improve healthcare&#46; A correct diagnosis is the first step in the effective treatment of a disease&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:7 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;F&#46; Widal"
                            1 => "P&#46; Abrami"
                            2 => "J&#46; Lermoyez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1922"
                        "editorial" => "La Presse M&#233;dicale"
                        "editorialLocalizacion" => "Paris"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diagnosis&#44; Prevention and Treatment of Aspirin-Induced Asthma and Rhinitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "G&#46; Bochenek"
                            1 => "K&#46; Banska"
                            2 => "Z&#46; Szabo"
                            3 => "E&#46; Nizankowska"
                            4 => "A&#46; Szczeklik"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Current Drug Targets &#8211; Inflammation &#38;Allergy"
                        "fecha" => "2002"
                        "numero" => "1"
                        "paginaInicial" => "1"
                        "paginaFinal" => "11"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25772178"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cross sensitivity with acetaminophen in aspirin-sensitive subjects with asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;A&#46; Settipane"
                            1 => "D&#46;D&#46; Stevenson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clinical Immunology"
                        "fecha" => "1989"
                        "volumen" => "84"
                        "numero" => "1"
                        "paginaInicial" => "26"
                        "paginaFinal" => "33"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Aspirin and Asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "K&#46;S&#46; Babu"
                            1 => "S&#46;S&#46; Salvi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2000"
                        "volumen" => "118"
                        "paginaInicial" => "1470"
                        "paginaFinal" => "1476"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11083703"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin intolerant asthmatics"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "B&#46; Dahlen"
                            1 => "E&#46; Nizankowska"
                            2 => "A&#46; Szczeliik"
                            3 => "G&#46; Bochenek"
                            4 => "M&#46; Kumlin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Respiratory Care Med"
                        "fecha" => "1998"
                        "volumen" => "157"
                        "paginaInicial" => "11887"
                        "paginaFinal" => "11896"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The pivotal role of lipoxigenase products in the reaction of aspirin sensitive asthmatics to aspirin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46; Israel"
                            1 => "E&#46;R&#46; Fisher"
                            2 => "M&#46;A&#46; Rosenberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm/148.6_Pt_1.1447"
                      "Revista" => array:5 [
                        "tituloSerie" => "Am Rev Respiratory Dis"
                        "fecha" => "1993"
                        "volumen" => "148"
                        "paginaInicial" => "1447"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8256883"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long term effects of asthma desensitization &#8211; treatment of aspirin induced rhinosinusitis-asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;M&#46; Sweet"
                            1 => "D&#46;D&#46; Stevenson"
                            2 => "D&#46;A&#46; Mathison"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "J Clin Immunol"
                        "fecha" => "1990"
                        "volumen" => "85"
                        "paginaInicial" => "59"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "pt"
  "url" => "/21735115/0000001200000006/v1_201305151431/S2173511506704304/v1_201305151431/pt/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9551"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Review Article&#47;Artigo de Revis&#227;o"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001200000006/v1_201305151431/S2173511506704304/v1_201305151431/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506704304?idApp=UINPBA00004E"
]
Article information
ISSN: 21735115
Original language: Portuguese
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 6 5 11
2024 October 34 40 74
2024 September 28 28 56
2024 August 41 32 73
2024 July 31 27 58
2024 June 27 26 53
2024 May 27 23 50
2024 April 27 22 49
2024 March 22 21 43
2024 February 18 17 35
2024 January 15 27 42
2023 December 27 19 46
2023 November 16 23 39
2023 October 13 27 40
2023 September 33 35 68
2023 August 22 16 38
2023 July 22 35 57
2023 June 19 29 48
2023 May 20 29 49
2023 April 16 9 25
Show all

Follow this link to access the full text of the article

Pulmonology

Are you a health professional able to prescribe or dispense drugs?