Chorioamnionitis and lung damage in the extremely low birth weight infant
Corioamnionite e lesão pulmonar no recém-nascido de extremo baixo peso
Gustavo Rocha1,
, Elisa Proença2, Conceição Quintas3, Teresa Rodrigues4, Hercília Guimarães5
Corresponding author
gusrocha@oninet.pt
Correspondence/Correspondência: Serviço de Neonatologia / Departamento de Pediatria, Hospital de São João – Piso 2, Alameda Prof. Hernâni Monteiro, 4202 – 451 Porto, Portugal. Tel.: +351 225095816 Fax: +351225512273.
Correspondence/Correspondência: Serviço de Neonatologia / Departamento de Pediatria, Hospital de São João – Piso 2, Alameda Prof. Hernâni Monteiro, 4202 – 451 Porto, Portugal. Tel.: +351 225095816 Fax: +351225512273.
1 Assistente Hospitalar. Pediatric Department, Division of Neonatology, Hospital de São João, University Hospital
2 Assistente Hospitalar. Pediatric Department, Maternidade Júlio Dinis
3 Assistente Hospitalar. Pediatric Department, Division of Neonatology, Centro Hospitalar de Vila Nova de Gaia
4 Assistente Hospitalar. Obstetrics and Gynecology Department, Epidemiology Department, Hospital de São João, University Hospital
5 Chefe de Serviço. Pediatric Department, Division of Neonatology, Hospital de São João, University Hospital
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Pediatric Department, Division of Neonatology, Hospital de São João, University Hospital" "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Assistente Hospitalar. Pediatric Department, Maternidade Júlio Dinis" "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Assistente Hospitalar. Pediatric Department, Division of Neonatology, Centro Hospitalar de Vila Nova de Gaia" "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Assistente Hospitalar. Obstetrics and Gynecology Department, Epidemiology Department, Hospital de São João, University Hospital" "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0020" ] 4 => array:3 [ "entidad" => "Chefe de Serviço. Pediatric Department, Division of Neonatology, Hospital de São João, University Hospital" "etiqueta" => "<span class="elsevierStyleSup">5</span>" "identificador" => "aff0025" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "<span class="elsevierStyleBold"><span class="elsevierStyleItalic">Correspondence</span>/Correspondência</span>: Serviço de Neonatologia / Departamento de Pediatria, Hospital de São João – Piso 2, Alameda Prof. Hernâni Monteiro, 4202 – 451 Porto, Portugal. Tel.: +351 225095816 Fax: +351225512273." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Corioamnionite e lesão pulmonar no recém-nascido de extremo baixo peso" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-02-10" "fechaAceptado" => "2007-03-26" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec159273" "palabras" => array:3 [ 0 => "Chorioamnionitis" 1 => "bronchopulmonary dysplasia" 2 => "respiratory distress syndrome" ] ] ] "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec159274" "palabras" => array:3 [ 0 => "Corioamnionite" 1 => "displasia broncopulmonar" 2 => "doença das membranas hialinas" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Some experimental work suggests that exposure to intrauterine infection is associated, not only, with lung maturation and a reduced risk of respiratory distress syndrome, but also, with delayed alveolarization and increased risk of bronchopulmonary dysplasia.</p> <span class="elsevierStyleSectionTitle">Aim</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">To evaluate the association between histological chorioamnionitis and lung disease in extremely low birth weight preterm infants.</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">A retrospective chart review of 63 less than 1000<span class="elsevierStyleHsp" style=""></span>g birthweight, appropriated for gestational age neonates, delivered at three tertiary medical centers in the north of Portugal, between 2001 and 2002. The association between histological chorioamnionitis and lung damage (respiratory distress syndrome and bronchopulmonary dysplasia) was evaluated through the calculation of crude and adjusted odds ratio.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">There were 32 newborns from mothers with histological chorioamnionitis and 31 without the condition. The association between histological chorioamnionitis and respiratory distress syndrome was OR 0.23 (95% CI 0.01 – 2.51). The association between chorioamnionitis and bronchopulmonary dysplasia was OR 1.61 (95% CI 0.38 – 6.97). The association between histological chorioamnionitis and bronchopulmonary dysplasia when adjusted for gestational age, multiple birth and C-section revealed no statistical significance: OR 2.66 (95% CI 0.36 – 19.60) for chorioamnionitis without funisitis or vasculitis and OR 1.68 (95% CI 0.25 – 11.18) for funisitis and/or vasculitis.</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">In this study we could not confirm a decreased risk of respiratory distress syndrome nor an increased risk of bronchopulmonary dysplasia in extremely low birth weight preterm neonates with histological chorioamnionitis.</p>" ] "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Alguns estudos experimentais sugerem que a exposição a infecção intra-uterina associa-se, não só, a maturação pulmonar e menor risco de doença das membranas hialinas, mas também a atraso na formação alveolar e maior risco de displasia broncopulmonar.</p> <span class="elsevierStyleSectionTitle">Objectivo</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Avaliar a associação entre corioamnionite histológica e lesão pulmonar no recém-nascido pré-termo de extremo baixo peso.</p> <span class="elsevierStyleSectionTitle">Métodos</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Estudo retrospectivo em 63 recém-nascidos com peso ao nascimento inferior a 1000<span class="elsevierStyleHsp" style=""></span>g, apropriados à idade gestacional, nascidos em três centros hospitalares do Norte de Portugal, entre 2001 e 2002. A associação entre corioamnionite histológica e lesão pulmonar (doença das membranas hialinas e displasia broncopulmonar) foi avaliada através do cálculo de <span class="elsevierStyleItalic">odds ratio</span>.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Em 32 recém-nascidos as mães apresentaram corioamnionite histológica e em 31 a condição não estava presente. A associação entre corioamnionite histológica e doença das membranas hialinas foi OR 0,23 (IC 95% 0,01 – 2,51). A associação entre corioamnionite histológica e displasia broncopulmonar foi OR 1,61 (IC 95% 0,38 – 6,97). A associação entre corioamnionite histológica e displasia broncopulmonar ajustada para a idade gestacional, gestação múltipla e parto por cesariana não foi estatisticamente significativa: OR 2,66 (IC 95% 0,36 – 19,60) para corioamnionite sem funisite ou vasculite e OR 1,68 (IC 95% 0,25 – 11,18) para corioamnionite com funisite e/ou vasculite.</p> <span class="elsevierStyleSectionTitle">Conclusão</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Este estudo não nos permitiu confirmar a existência de menor risco de doença das membranas hialinas ou de maior risco de displasia broncopulmonar no recém-nascido pré-termo de extremo baixo peso com corioamnionite histológica.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliography" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:32 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pathogenesis of preterm labor and preterm premature rupture of membranes associated with intra-amniotic infection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R. Gomez" 1 => "R. Romero" 2 => "S.S. Edwin" 3 => "C. David" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Infect Dis Clin North Am" "fecha" => "1997" "volumen" => "11" "paginaInicial" => "135" "paginaFinal" => "176" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9067790" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inflammation and bronchopulmonary dysplasia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "C.P. Speer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Semin Neonatol" "fecha" => "2003" "volumen" => "8" "paginaInicial" => "29" "paginaFinal" => "38" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12667828" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of antenatal endotoxin and glucocorticoids on the lungs of preterm lambs" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.H. Jobe" 1 => "J.P. Newnham" 2 => "K.E. Willet" 3 => "P. Sly" 4 => "M.G. Ervin" 5 => "C. Bachurski" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Obstet Gynecol" "fecha" => "2000" "volumen" => "182" "paginaInicial" => "401" "paginaFinal" => "408" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10694344" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Antenatal endotoxin and glucocorticoid effects on lung morphometry in preterm lambs" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "K.E. Willet" 1 => "A.H. Jobe" 2 => "M. Ikegami" 3 => "J. Newnham" 4 => "S. Brennan" 5 => "P.D. Sly" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1203/00006450-200012000-00013" "Revista" => array:6 [ "tituloSerie" => "Pediatr Res" "fecha" => "2000" "volumen" => "48" "paginaInicial" => "782" "paginaFinal" => "788" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11102547" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chorioamnionitis and inflammation of the fetal lung" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "B. Schmidt" 1 => "L. Cao" 2 => "S. Mackensen-Haen" 3 => "H. Kendziorra" 4 => "K. Klingel" 5 => "C.P. Speer" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1067/mob.2001.113321" "Revista" => array:6 [ "tituloSerie" => "Am J Obstet Gynecol" "fecha" => "2001" "volumen" => "185" "paginaInicial" => "173" "paginaFinal" => "177" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11483924" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mucosal tumor necrosis factor-alpha production and extensive disruption of sulphated glycosaminoglycans begin within hours of birth in neonatal respiratory distress syndrome" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:7 [ 0 => "S.H. Murch" 1 => "K. Costeloe" 2 => "N.J. Klein" 3 => "H. Rees" 4 => "N. McIntosh" 5 => "J.W. Keeling" 6 => "T.T. MacDonald" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1203/00006450-199609000-00019" "Revista" => array:6 [ "tituloSerie" => "Pediatr Res" "fecha" => "1996" "volumen" => "40" "paginaInicial" => "484" "paginaFinal" => "489" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8865288" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Amniotic fluid tumor necrosis factor alpha and the risk of respiratory distress syndrome among preterm infants" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:7 [ 0 => "J. Hitti" 1 => "M.A. Krohn" 2 => "D.L. Patton" 3 => "P. Tarczy-Hornoch" 4 => "S.L. Hillier" 5 => "E.M. Cassen" 6 => "D.A. Eschenbach" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Obstet Gynecol" "fecha" => "1997" "volumen" => "177" "paginaInicial" => "50" "paginaFinal" => "56" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9240582" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chorioamnionitis, mechanical ventilation, and postnatal sepsis as modulators of chronic lung disease in preterm infants" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L.J. Van Marter" 1 => "O. Dammann" 2 => "E.N. Allred" 3 => "A. Leviton" 4 => "M. Pagano" 5 => "M. Moore" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1067/mpd.2002.121381" "Revista" => array:6 [ "tituloSerie" => "J Pediatr" "fecha" => "2002" "volumen" => "140" "paginaInicial" => "171" "paginaFinal" => "176" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11865267" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Placental and other perinatal risk factors for chronic lung disease in very low birth weight infants" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R.W. Redline" 1 => "D. Wilson-Costello" 2 => "M. Hack" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1203/00006450-200211000-00017" "Revista" => array:6 [ "tituloSerie" => "Pediatr Res" "fecha" => "2002" "volumen" => "52" "paginaInicial" => "713" "paginaFinal" => "719" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12409518" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chorioamnionitis/funisitis and the development of bronchopulmonary dysplasia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Kent" 1 => "J.E. Dahlstrom" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1440-1754.2004.00366.x" "Revista" => array:6 [ "tituloSerie" => "J Paediatr Child Health" "fecha" => "2004" "volumen" => "40" "paginaInicial" => "356" "paginaFinal" => "359" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15228562" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "American Academy of Pediatrics. Committee on Fetus and Newborn . Perinatal Care at the Threshold of Viability" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "H. MacDonald" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "2002" "volumen" => "110" "paginaInicial" => "1024" "paginaFinal" => "1027" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12415047" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New Ballard Score, expanded to include extremely premature infants" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J.L. Ballard" 1 => "J.C. Khoury" 2 => "K. Wedig" 3 => "L. Wang" 4 => "B.L. Eilers- -Walsman" 5 => "R. Lipp" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Pediatr" "fecha" => "1991" "volumen" => "119" "paginaInicial" => "417" "paginaFinal" => "423" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1880657" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A United States national reference for fetal growth" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "G.R. Alexander" 1 => "J.H. Himes" 2 => "R.B. Kaufman" 3 => "J. Mor" 4 => "M. Kogan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/0029-7844(95)00386-X" "Revista" => array:6 [ "tituloSerie" => "Obstet Gynecol" "fecha" => "1996" "volumen" => "87" "paginaInicial" => "163" "paginaFinal" => "168" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8559516" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pathology of the Placenta, Membranes, and Umbilical Cord in Bacterial, Fungal, and Viral Infections in Man" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "W.A. Blanc" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:2 [ "titulo" => "International Academy of Pathology monograph Perinatal Diseases by 14 authors" "serieFecha" => "1981" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Antenatal corticosteroid therapy: a meta- -analysis of randomized trials, 1972 to 1994" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P.A. Crowley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Obstet Gynecol" "fecha" => "1995" "volumen" => "173" "paginaInicial" => "322" "paginaFinal" => "335" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7631713" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Idiopathic respiratory distress syndrome of the newborn" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.J. Rudolph" 1 => "C.A. Smith" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Pediatr" "fecha" => "1960" "volumen" => "57" "paginaInicial" => "905" "paginaFinal" => "921" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchopulmonary dysplasia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.H. Jobe" 1 => "E. Bancalari" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Respi Crit Care Med" "fecha" => "2001" "volumen" => "163" "paginaInicial" => "1723" "paginaFinal" => "1729" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chorioamnionitis, cortisol, and acute lung disease in very low birth weight infants" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K.L. Watterberg" 1 => "S.M. Scott" 2 => "R.L. Naeye" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Pediatrics" "fecha" => "1997" "volumen" => "99" "paginaInicial" => "E6" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9164802" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R. Sapolsky" 1 => "C. Rivier" 2 => "G. Yamamoto" 3 => "P. Plotsky" 4 => "W. Vale" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Science" "fecha" => "1987" "volumen" => "238" "paginaInicial" => "522" "paginaFinal" => "524" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2821621" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Release of multiple hormones by a direct action of interleukin-1 on pituitary cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E.W. Bernton" 1 => "J.E. Beach" 2 => "J.W. Holaday" 3 => "R.C. Smallridge" 4 => "H.G. Fein" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Science" "fecha" => "1987" "volumen" => "238" "paginaInicial" => "519" "paginaFinal" => "521" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2821620" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Regulation of fetal lung maturation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "I. Gross" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Physiol" "fecha" => "1990" "volumen" => "259" "paginaInicial" => "337" "paginaFinal" => "344" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "the interactive effects of endotoxin with prenatal glucocorticoids on short-term lung function in sheep" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:8 [ 0 => "J.P. Newnham" 1 => "T.J. Moss" 2 => "J.F. Padbury" 3 => "K.E. Willet" 4 => "M. Ikegami" 5 => "M.G. Ervin" 6 => "P. Sly" 7 => "A. Jobe" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1067/mob.2001.114500" "Revista" => array:6 [ "tituloSerie" => "Am J Obstet Gynecol" "fecha" => "2001" "volumen" => "185" "paginaInicial" => "190" "paginaFinal" => "197" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11483927" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The new BPD: An arrest of lung development" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.H. Jobe" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatr Res" "fecha" => "1999" "volumen" => "46" "paginaInicial" => "641" "paginaFinal" => "643" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10590017" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Abnormal pulmonary outcomes in premature infants: Prediction from oxygen requirement in the neonatal period" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A.T. Shennan" 1 => "M.S. Dunn" 2 => "A. Ohlsson" 3 => "K. Lennox" 4 => "E.M. Hoskins" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "1988" "volumen" => "82" "paginaInicial" => "527" "paginaFinal" => "532" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3174313" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inflammatory mechanisms in neonatal chronic lung disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "C.P. Speer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Eur J Pediatr" "fecha" => "1999" "volumen" => "158" "numero" => "suppl 1" "paginaInicial" => "18" "paginaFinal" => "22" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9950302" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Amniotic fluid cytokines (interleukin 6, tumour necrosis factor alpha, interleukin 1b, and interleukin 8) and the risk for the development of bronchopulmonary dysplasia" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "B.H. Yoon" 1 => "R. Romero" 2 => "J.K. Jun" 3 => "K.H. Park" 4 => "J.D. Park" 5 => "F. Ghezzi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Obstet Gynecol" "fecha" => "1997" "volumen" => "177" "paginaInicial" => "825" "paginaFinal" => "830" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9369827" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A systemic fetal inflammatory response and the development of bronchopulmonary dysplasia" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "B.H. Yoon" 1 => "R. Romero" 2 => "K.S. Kim" 3 => "J.S. Park" 4 => "S.H. Ki" 5 => "B.I. Kim" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Obstet Gynecol" "fecha" => "1999" "volumen" => "181" "paginaInicial" => "773" "paginaFinal" => "779" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10521727" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchoalveolar inflammation following airway infection in preterm infants with chronic lung disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "P. Groneck" 1 => "J. Schmale" 2 => "V. Soditt" 3 => "H. Stutzer" 4 => "B. Gotze- -Speer" 5 => "C.P. Speer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatr Pulmonol" "fecha" => "2001" "volumen" => "31" "paginaInicial" => "331" "paginaFinal" => "338" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11340678" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Re-evaluation of chorioamnionitis and funisitis with a special reference to subacute chorioamnionitis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Ohyama" 1 => "Y. Itani" 2 => "M. Yamanaka" 3 => "A. Goto" 4 => "K. Kato" 5 => "R. Ijiri" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Hum Pathol" "fecha" => "2002" "volumen" => "33" "paginaInicial" => "183" "paginaFinal" => "190" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11957143" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung and brain damage in preterm newborns. Are they related? How? Why?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "O. Dammann" 1 => "A. Leviton" 2 => "D.B. Bartels" 3 => "C.E. Dammann" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000078175" "Revista" => array:6 [ "tituloSerie" => "Biol Neonate" "fecha" => "2004" "volumen" => "85" "paginaInicial" => "305" "paginaFinal" => "313" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15218288" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib31" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Necrotizing funisitis: Clinical significance and association with chronic lung disease in premature infants" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:7 [ 0 => "T. Matsuda" 1 => "T. Nakajima" 2 => "S. Hattori" 3 => "K. Hanatani" 4 => "Y. Fukazawa" 5 => "K. Kosayashi" 6 => "S. Fujimoto" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Obstet Gynecol" "fecha" => "1997" "volumen" => "177" "paginaInicial" => "1402" "paginaFinal" => "1407" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9423742" "web" => "Medline" ] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib32" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inflammatory markers in intrauterine and fetal blood and cerebrospinal fluid compartments are associated with adverse pulmonary and neurologic outcomes in preterm infants" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R.M. Viscardi" 1 => "C.K. Muhumuza" 2 => "A. Rodriguez" 3 => "K.D. Fairchild" 4 => "C.C. Sun" 5 => "G.W. Gross" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1203/01.pdr.0000127015.60185.8a" "Revista" => array:6 [ "tituloSerie" => "Pediatr Res" "fecha" => "2004" "volumen" => "55" "paginaInicial" => "1009" "paginaFinal" => "1017" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15155869" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735115/0000001300000005/v1_201305151444/S2173511507703706/v1_201305151444/en/main.assets" "Apartado" => array:4 [ "identificador" => "9550" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case Report/Caso Clínico" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001300000005/v1_201305151444/S2173511507703706/v1_201305151444/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511507703706?idApp=UINPBA00004E" ]
| Year/Month | Html | Total | |
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| 2024 November | 4 | 4 | 8 |
| 2024 October | 28 | 31 | 59 |
| 2024 September | 32 | 22 | 54 |
| 2024 August | 36 | 29 | 65 |
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| 2024 April | 19 | 24 | 43 |
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| 2024 January | 13 | 25 | 38 |
| 2023 December | 22 | 27 | 49 |
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| 2023 September | 18 | 37 | 55 |
| 2023 August | 13 | 19 | 32 |
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| 2023 May | 21 | 26 | 47 |
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