Défice de alfa-1 antitripsina. A propósito de dois casos clínicos
Alpha-1 antitrypsin deficiency. Two cases report
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A propósito de dois casos clínicos" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "295" "paginaFinal" => "302" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "Sónia Serra, Graça Banha, Paula Duarte" "autores" => array:3 [ 0 => array:3 [ "nombre" => "Sónia" "apellidos" => "Serra" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0020" ] ] ] 1 => array:3 [ "nombre" => "Graça" "apellidos" => "Banha" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0020" ] ] ] 2 => array:3 [ "nombre" => "Paula" "apellidos" => "Duarte" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0015" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0020" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Interna do Complementar de Medicina Interna" "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Assistente Hospitalar Graduada de Pneumologia" "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Serviço de Pneumologia" "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Centro Hospitalar de Setúbal, EPE, Rua Camilo Castelo Branco, 2910-446 Setúbal – Portugal." "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0020" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Alpha-1 antitrypsin deficiency. Two cases report" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-10-01" "fechaAceptado" => "2007-10-26" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec159505" "palabras" => array:3 [ 0 => "Defice de alfa-1 antitripsina" 1 => "fenotipo Pi ZZ" 2 => "enfisema" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec159504" "palabras" => array:3 [ 0 => "Alpha-1 antitrypsin deficiency" 1 => "phenotype Pi ZZ" 2 => "emphysema" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">O defice de alfa-1 antitripsina e uma doenca hereditaria autossomica codominante. O fenotipo Pi ZZ esta associado com maior frequencia a doenca pulmonar, sendo responsavel pelo aparecimento precoce de enfisema, sobretudo nos fumadores. Os autores apresentam dois casos de diagnostico tardio e em que estiveram presentes outros factores que terao contribuido para o aparecimento de manifestacoes clinicas.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The alpha-1 antitrypsin deficiency is an hereditary autosomic codominant disease. The phenotype Pi ZZ is associated more frequently with pulmonary disease and is responsible for the presence of emphysema early in life, particularly in smokers. The author's present two cases which diagnosis were performed later in life and in which other factors could be also responsible for clinical manifestations.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:17 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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Article information
ISSN: 21735115Original language: Portuguese
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