Correspondence: Serviço de Neonatologia / Departamento de Pediatria, Hospital de São João – Piso 2, Alameda Prof. Hernâni Monteiro, 4202 – 451 Porto, Portugal. Tel.: +351 225095816, Fax: +351225512273.
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Tel.: +351 225095816, Fax: +351225512273." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Infecção por Bordetella pertussis com hipertensão pulmonar grave num recém-nascido com boa evolução clínica – Caso clínico" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-02-22" "fechaAceptado" => "2008-05-27" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec159758" "palabras" => array:5 [ 0 => "Neonate" 1 => "nitric oxide" 2 => "pertussis" 3 => "pulmonary hypertension" 4 => "sildenafil" ] ] ] "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec159757" "palabras" => array:5 [ 0 => "Recém-nascido" 1 => "oxido nítrico" 2 => "<span class="elsevierStyleItalic">pertussis</span>" 3 => "hipertensão pulmonar" 4 => "sildenafil" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">In spite of the availability and widespread use of vaccines, pertussis is far from controlled. Newborns and infants too young to be fully vaccinated, born from mothers with low antibody titers to <span class="elsevierStyleItalic">Bordetella pertussis</span>, are highly susceptible to infection and at risk of severe disease and death. Pertussis associated with pulmonary hypertension in the newborn is often fatal. The authors report a clinical case of severe pertussis-induced respiratory failure associated to severe pulmonary hypertension in a neonate successfully treated with sildenafil and inhaled nitric oxide.</p>" ] "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Apesar da ampla cobertura vacinal, a infecção por <span class="elsevierStyleItalic">Bordetella pertussis</span> está longe de estar controlada. Os recém-nascidos e lactentes ainda sem imunização completa e filhos de mães com baixos títulos de anticorpos para a <span class="elsevierStyleItalic">Bordetella pertussis</span> são altamente susceptíveis à infecção e têm maior risco de doença grave e morte. A infecção por <span class="elsevierStyleItalic">Bordetella pertussis</span> associada a hipertensão pulmonar no recém-nascido é frequentemente fatal. Os autores descrevem um caso clínico de doença grave num recém-nascido com insuficiência respiratória aguda e hipertensão pulmonar grave, tratado com sucesso com sildenafil e óxido nítrico inalado.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "nota" => "<p class="elsevierStyleNotepara">Faculty of Medicine of Porto University, Porto, Portugal</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliography" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bacterial infections of the respiratory tract" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E.D. Barnett" 1 => "J.O. 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Year/Month | Html | Total | |
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