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Costa, R. Rocha, M. Tavares, A. Bonito-Vítor, L. Guedes-Vaz, Hospital S. João" "autores" => array:6 [ 0 => array:2 [ "nombre" => "S." "apellidos" => "Costa" ] 1 => array:2 [ "nombre" => "R." "apellidos" => "Rocha" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Tavares" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Bonito-Vítor" ] 4 => array:2 [ "nombre" => "L." "apellidos" => "Guedes-Vaz" ] 5 => array:2 [ "nombre" => "Hospital S." "apellidos" => "João" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511509700880?idApp=UINPBA00004E" "url" => "/21735115/0000001500000001/v1_201305151504/S2173511509700880/v1_201305151504/en/main.assets" ] "pt" => array:14 [ "idiomaDefecto" => true "titulo" => "Projecto de estadiamento do cancro do pulmão pela IASLC: Estudo comparativo entre a 6.ª edição TNM em vigor e a 7.ª edição proposta" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "67" "paginaFinal" => "76" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "Lina Carvalho, Edgar Cardoso, Henrique Nunes, Victor Baptista, Ana Gomes, Patrícia Couceiro" "autores" => array:6 [ 0 => array:3 [ "nombre" => "Lina" "apellidos" => "Carvalho" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "Edgar" "apellidos" => "Cardoso" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Henrique" "apellidos" => "Nunes" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "Victor" "apellidos" => "Baptista" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] ] ] 4 => array:3 [ "nombre" => "Ana" "apellidos" => "Gomes" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0015" ] ] ] 5 => array:3 [ "nombre" => "Patrícia" "apellidos" => "Couceiro" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Professora de Anatomia Patológica" "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Disciplina de Oncologia" "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Investigadoras CIMAGO – Centro de Investigação em Meio Ambiente, Genética e Oncologia da Faculdade de Medicina da Universidade de Coimbra" "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0015" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "The IASLC lung cancer staging project. Comparing the current 6<span class="elsevierStyleSup">th</span> TNM edition with the proposed 7<span class="elsevierStyleSup">th</span> edition" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-09-12" "fechaAceptado" => "2008-10-15" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec159899" "palabras" => array:2 [ 0 => "7.ª edição TNM" 1 => "cancro do pulmão" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec159898" "palabras" => array:2 [ 0 => "7th TNM edition" 1 => "lung cancer" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A futura 7.ª edição TNM da Classificação de Tumores Malignos, a publicar em 2009, contempla várias recomendações estabelecidas pela IASLC para alterações nos componentes T, N e M, no que diz respeito ao estadiamento do cancro do pulmão. As alterações no estadiamento global dos doentes, que decorrem destas recomendações, incluem: a reclassificação de tumores com mais de 7cm de T2 para T3; a mudança de algumas categorias dadas a nódulos pulmonares tumorais adicionais em algumas localizações; reclassificar o derrame pleural como componente M; devendo ainda mover -se os casos T2b N0 M0 do estádio IB para o IIA, os casos T2a N1 M0 do estádio IIB para IIA e os casos T4 N0 -1 M0 do estádio IIIB para IIIA.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Foram aplicadas as definições da nova proposta TNM – 7.ª edição a 203 casos de carcinoma broncopulmonar, correspondendo a carcinoma epidermóide (83) e adenocarcinoma (120) em estádios cirúrgicos, da casuística do Serviço de Anatomia Patológica dos Hospitais da Universidade de Coimbra, tendo-se verificado as seguintes alterações: vinte casos no estádio IB movidos para o estádio IIA e três casos movidos para IIB; dezoito casos no estádio IIB movidos para o estádio IIA e um caso movido para IIIA; dois casos no estádio IIIB movidos para o estádio IV; seis casos no estádio IV movidos para o estádio IIIA e um caso movido para o estádio IIIB. Conclui-se assim que ocorreram alterações de estadiamento global dos doentes em 51 dos 203 casos analisados (25,1%).</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">The future 7th edition of TNM classification for lung cancer will be published in 2009 and comprises the IASLC recommendations for TNM parameters. The general staging of lung cancer includes the new parameters: reclassification of tumours larger than 7 cm from T2 to T3; extra tumoral nodules will change their category to T3, T4 and M1 when in the same, ipsilateral or contralateral lobe, respectively; pleural effusion will be M1a. With these alterations, cases staged as IB – T2b N0 M0 will be IIA, cases staged IIB – T2a N1 M0 will be IIA and cases IIIB– T4 N0-1 M0 will be IIIA.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The 7<span class="elsevierStyleSup">th</span> TNM edition recommendations were applied to 203 broncho-pulmonary carcinomas, concerning epidermoid carcinomas (83) and adenocarcinomas (120) registered in the archive of the Serviço de Anatomia Patológica of the Hospitais da Universidade de Coimbra – Portugal, previously submitted to surgical resection and lymph node excision. The following alterations will be kept as the application of the future 7<span class="elsevierStyleSup">th</span> TNM edition: 20 cases in stage IB will move to stage IIA (17) and stage IIB (3); 18 cases will change from stage IIB to stage IIA (17) and 1 case to stage IIIA; 2 cases from stage IIIB will move to stage IV; 6 cases in stage IV will move to stage IIIA (5) and 1 case to stage IIIB. In this translational adaptation from 6<span class="elsevierStyleSup">th</span> to 7<span class="elsevierStyleSup">th</span> TNM staging, 51 out of the 203 analysed cases change their staging, corresponding to 25.1%.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:11 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The IASLC Lung Cancer Staging Project: proposals regarding the clinical staging of Small Cell Lung Cancer in the forthcoming (seventh) edition of the TNM classification for lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "F.A. Shepherd" 1 => "J. Crowley" 2 => "P.V. Houtte" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/JTO.0b013e31815bdc0d" "Revista" => array:6 [ "tituloSerie" => "J Thorac Oncol" "fecha" => "2007" "volumen" => "2" "paginaInicial" => "1067" "paginaFinal" => "1077" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18090577" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The IASLC Lung Cancer Staging Project: validation of the proposals for revision of the T N and M descriptors and consequent stage groupings in the forthcoming (seventh) edition of the TNM classification for lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "P.A. Groome" 1 => "V. Bolejack" 2 => "J.J. Crowley" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/JTO.0b013e31812d05d5" "Revista" => array:6 [ "tituloSerie" => "J Thorac Oncol" "fecha" => "2007" "volumen" => "2" "paginaInicial" => "694" "paginaFinal" => "705" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17762335" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification for lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "P. Goldstraw" 1 => "J. Crowley" 2 => "K. 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Giroux" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/JTO.0b013e31807ec803" "Revista" => array:6 [ "tituloSerie" => "J Thorac Oncol" "fecha" => "2007" "volumen" => "2" "paginaInicial" => "603" "paginaFinal" => "612" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17607115" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The IASLC Lung Cancer Staging Project: Proposals for revision of the M descriptors in the forthcoming (seventh) edition of the TNM classification for lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "P.E. Postmus" 1 => "K. Chansky" 2 => "J.J. Crowley" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/JTO.0b013e31811f4703" "Revista" => array:6 [ "tituloSerie" => "J Thorac Oncol" "fecha" => "2007" "volumen" => "2" "paginaInicial" => "686" "paginaFinal" => "693" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17762334" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Validation of the proposed IASLC Non-small Cell Lung Cancer staging system revisions for advanced bronchioloalveolar carcinoma using data from the California Cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "J.A. Zell" 1 => "S-HI Ou" 2 => "A. Ziogas" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/JTO.0b013e31815ba260" "Revista" => array:6 [ "tituloSerie" => "J Thorac Oncol" "fecha" => "2007" "volumen" => "2" "paginaInicial" => "1078" "paginaFinal" => "1085" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18090578" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Validation study of the proposed IASLC staging revisions of the T4 and M non-small cell lung cancer descriptors using data from 23,583 patients in the California Cancer Registry" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S-HI Ou" 1 => "J.A. Zell" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/JTO.0b013e318164545d" "Revista" => array:6 [ "tituloSerie" => "J Thorac Oncol" "fecha" => "2008" "volumen" => "3" "paginaInicial" => "216" "paginaFinal" => "227" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18317063" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The International Epidemiology of Lung Cancer Geographical distribution and secular trends" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D.R. Youlden" 1 => "S.M. Cramb" 2 => "P.D. Baade" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/JTO.0b013e31818020eb" "Revista" => array:6 [ "tituloSerie" => "J Thorac Oncol" "fecha" => "2008" "volumen" => "3" "paginaInicial" => "819" "paginaFinal" => "831" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18670299" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The impact of additional prognostic factors on survival and their relationship with the anatomical extent of disease expressed by the 6th edition of the TNM classification of malignant tumors and the proposals for the 7th edition" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "J.P. Sculier" 1 => "K. Chansky" 2 => "J.J. 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Original language: Portuguese
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