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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Tuberculosis is a leading cause of world-wide mortality and morbidity&#46; A reduced rate of tuberculosis in people aged less than 15 years has been seen in Portugal over the last decade of the twentieth century&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Retrospective analysis of tuberculosis cases in children admitted to the Centro Hospitalar de Vila Nova de Gaia January 1 2000 to December 31 2007&#46; The individual epidemiological&#44; clinical&#44; radiological&#44; microbiological and treatment information was analysed&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">We found 23 cases of tuberculosis disease &#40;78&#37; pulmonary tuberculosis and 22&#37; extra-pulmonary tuberculosis&#41;&#46; Children&#39;s ages varied from 6 months to 16 years&#44; with the male gender predominant&#46; All patients had previously been vaccinated with BCG and there was a prior contact with TB in 57&#37;&#46; 2007 was the year with the highest number of cases&#46; The Mantoux test was positive in 91&#37; cases and <span class="elsevierStyleItalic">M&#46; tuberculosis</span> isolation was possible in 61&#37;&#46; Gastric fluid analysis allowed isolation in 1&#47;3 of cases and bronchoscopy contributed to <span class="elsevierStyleItalic">M&#46; tuberculosis</span> isolation in 43&#37; cases with negative gastric fluid analysis&#46; Every patient underwent at least 6 months of tuberculostatic treatment&#44; without any documented resistances&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Tuberculosis remains a real problem&#44; with the diagnosis&#44; the search for contacts and adequate treatment &#40;including prophylaxis&#41; the main challenge&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introdu&#231;&#227;o</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A tuberculose &#40;TB&#41; &#233; uma importante causa de mortalidade e morbilidade mundial&#46; Em Portugal&#44; na &#250;ltima d&#233;cada do s&#233;culo xx&#44; assistiu-se a uma diminui&#231;&#227;o da incid&#234;ncia de TB no grupo et&#225;rio com menos de 15 anos&#46;</p> <span class="elsevierStyleSectionTitle">Material e m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">An&#225;lise retrospectiva dos casos de TB doen&#231;a em crian&#231;as internadas no Centro Hospitalar de Vila Nova de Gaia entre 1 de Janeiro de 2000 e 31 de Dezembro de 2007&#46; Analisaram-se os respectivos dados epidemiol&#243;gicos&#44; cl&#237;nicos&#44; radiol&#243;gicos&#44; microbiol&#243;gicos e terap&#234;uticos&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">No per&#237;odo estudado registaram-se 23 casos de tuberculose doen&#231;a &#40;78&#37; TB pulmonar e 22&#37; TB extrapulmonar&#41;&#46; A faixa et&#225;ria variou dos 6 meses aos 16 anos&#44; predominando o sexo masculino&#46; Todos os doentes tinham sido previamente vacinados com BCG e existia hist&#243;ria de contacto pr&#233;vio com TB em 57&#37;&#46; O ano de 2007 foi aquele em que ocorreu um maior n&#250;mero de casos&#46; A prova de Mantoux foi positiva em 91&#37; dos casos e o isolamento de <span class="elsevierStyleItalic">M&#46; tuberculosis</span> foi poss&#237;vel em 61&#37;&#46; A colheita de suco g&#225;strico permitiu o isolamento em 1&#47;3 dos casos e a broncoscopia contribuiu para o isolamento do <span class="elsevierStyleItalic">M&#46; tuberculosis</span> em 43&#37; dos casos com suco g&#225;strico negativo&#46; Todos os doentes efectuaram&#44; no m&#237;nimo&#44; 6 meses de tratamento com antibacilares&#44; n&#227;o sendo documentadas resist&#234;ncias&#46; Ap&#243;s internamento&#44; identificaram-se 43&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>10&#41; casos intrafamiliares de TB&#46;</p> <span class="elsevierStyleSectionTitle">Conclus&#227;o</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A tuberculose mant&#233;m-se um problema actual&#44; sendo o diagn&#243;stico&#44; o rastreio dos contactos e o cumprimento terap&#234;utico &#40;inclusive profil&#225;ctico&#41; um desafio fulcral na sua conten&#231;&#227;o&#46;</p>"
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Tuberculosis disease – Statistics of a paediatric department in the 21st century
Tuberculose doença – Casuística de um serviço de pediatria no século XXI
Ana Luísa Leite1,
Corresponding author
ana.luisa20@gmail.com

Correspondence to/Correspondência: Serviço de Pediatria, Centro Hospitalar de Vila Nova de Gaia – Unidade 2, Rua Dr. Francisco Sá Carneiro, 4400 – Vila Nova de Gaia.
, Isabel Carvalho2, Elvira Tavares3, António Vilarinho3
1 Interna Complementar de Pediatria/Resident, Paediatrics, Serviço de Pediatria, Centro Hospitalar de Vila Nova de Gaia / Espinho, EPE
2 Assistente Hospitalar de Pediatria/Consultant, Paediatrics, Serviço de Pediatria, Centro Hospitalar de Vila Nova de Gaia / Espinho, EPE
3 Chefe de Serviço/Department Head, Serviço de Pediatria, Centro Hospitalar de Vila Nova de Gaia / Espinho, EPE
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introdu&#231;&#227;o</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A tuberculose &#40;TB&#41; &#233; uma importante causa de mortalidade e morbilidade mundial&#46; Em Portugal&#44; na &#250;ltima d&#233;cada do s&#233;culo xx&#44; assistiu-se a uma diminui&#231;&#227;o da incid&#234;ncia de TB no grupo et&#225;rio com menos de 15 anos&#46;</p> <span class="elsevierStyleSectionTitle">Material e m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">An&#225;lise retrospectiva dos casos de TB doen&#231;a em crian&#231;as internadas no Centro Hospitalar de Vila Nova de Gaia entre 1 de Janeiro de 2000 e 31 de Dezembro de 2007&#46; Analisaram-se os respectivos dados epidemiol&#243;gicos&#44; cl&#237;nicos&#44; radiol&#243;gicos&#44; microbiol&#243;gicos e terap&#234;uticos&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">No per&#237;odo estudado registaram-se 23 casos de tuberculose doen&#231;a &#40;78&#37; TB pulmonar e 22&#37; TB extrapulmonar&#41;&#46; A faixa et&#225;ria variou dos 6 meses aos 16 anos&#44; predominando o sexo masculino&#46; Todos os doentes tinham sido previamente vacinados com BCG e existia hist&#243;ria de contacto pr&#233;vio com TB em 57&#37;&#46; O ano de 2007 foi aquele em que ocorreu um maior n&#250;mero de casos&#46; A prova de Mantoux foi positiva em 91&#37; dos casos e o isolamento de <span class="elsevierStyleItalic">M&#46; tuberculosis</span> foi poss&#237;vel em 61&#37;&#46; A colheita de suco g&#225;strico permitiu o isolamento em 1&#47;3 dos casos e a broncoscopia contribuiu para o isolamento do <span class="elsevierStyleItalic">M&#46; tuberculosis</span> em 43&#37; dos casos com suco g&#225;strico negativo&#46; Todos os doentes efectuaram&#44; no m&#237;nimo&#44; 6 meses de tratamento com antibacilares&#44; n&#227;o sendo documentadas resist&#234;ncias&#46; Ap&#243;s internamento&#44; identificaram-se 43&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>10&#41; casos intrafamiliares de TB&#46;</p> <span class="elsevierStyleSectionTitle">Conclus&#227;o</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A tuberculose mant&#233;m-se um problema actual&#44; sendo o diagn&#243;stico&#44; o rastreio dos contactos e o cumprimento terap&#234;utico &#40;inclusive profil&#225;ctico&#41; um desafio fulcral na sua conten&#231;&#227;o&#46;</p>"
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Pulmonology

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