Caso Clínico
Granulomatose de Wegener – Envolvimento otológico, nasal, laringotraqueal e pulmonar
Wegener granulomatosis – Otologic, nasal, tracheobronchial and pulmonary involvement
Sandra Figueiredo1,
, Laurentino Mendes Leal2, António Morais3, Adriana Magalhães4, Teresa Oliveira5, Venceslau Hespanhol4, Carlos Dias6, Gabriela Fernandes3,4,5,6
Corresponding author
1 Internato Médico. Serviço de Pneumologia)
2 Internato Médico. Serviço de Otorrinolaringologia
3 Assistente Hospitalar. Serviço de Pneumologia
4 Assistente Hospitalar Graduado. Serviço de Pneumologia
5 Assistente Hospitalar Graduada. Unidade de Cuidados Intensivos Polivalentes
6 Assistente Hospitalar Graduado. Serviço de Medicina Intern
Read
889
Timeswas read the article
471
Total PDF
418
Total HTML
Share statistics
array:24 [ "pii" => "S2173511509701630" "issn" => "21735115" "doi" => "10.1016/S2173-5115(09)70163-0" "estado" => "S300" "fechaPublicacion" => "2009-09-01" "aid" => "70163" "copyright" => "Sociedade Portuguesa de Pneumologia" "copyrightAnyo" => "2009" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "cor" "cita" => "Rev Port Pneumol. 2009;15:929-35" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3512 "formatos" => array:3 [ "EPUB" => 244 "HTML" => 2029 "PDF" => 1239 ] ] "itemSiguiente" => array:19 [ "pii" => "S2173511509701642" "issn" => "21735115" "doi" => "10.1016/S2173-5115(09)70164-2" "estado" => "S300" "fechaPublicacion" => "2009-09-01" "aid" => "70164" "copyright" => "Sociedade Portuguesa de Pneumologia" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "cor" "cita" => "Rev Port Pneumol. 2009;15:937-41" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3943 "formatos" => array:3 [ "EPUB" => 206 "HTML" => 1965 "PDF" => 1772 ] ] "pt" => array:10 [ "idiomaDefecto" => true "titulo" => "Hemotórax espontâneo em doente com neurofibromatose tipo I – A propósito de um caso clínico" "tienePdf" => "pt" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "pt" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "937" "paginaFinal" => "941" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Spontaneous hemothorax in a neurofibromatosis type I patient – A case report" ] ] "contieneResumen" => array:2 [ "pt" => true "en" => true ] "contienePdf" => array:1 [ "pt" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Alexandra Bento, Ana Paula Gonçalves" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Alexandra" "apellidos" => "Bento" ] 1 => array:2 [ "nombre" => "Ana Paula" "apellidos" => "Gonçalves" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511509701642?idApp=UINPBA00004E" "url" => "/21735115/0000001500000005/v1_201305151515/S2173511509701642/v1_201305151515/pt/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2173511509701629" "issn" => "21735115" "doi" => "10.1016/S2173-5115(09)70162-9" "estado" => "S300" "fechaPublicacion" => "2009-09-01" "aid" => "70162" "copyright" => "Sociedade Portuguesa de Pneumologia" "documento" => "simple-article" "crossmark" => 0 "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "cor" "cita" => "Rev Port Pneumol. 2009;15:923-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 4050 "formatos" => array:3 [ "EPUB" => 224 "HTML" => 2079 "PDF" => 1747 ] ] "pt" => array:10 [ "idiomaDefecto" => true "titulo" => "DPOC agudizada ou algo mais? Caso clínico" "tienePdf" => "pt" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "pt" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "923" "paginaFinal" => "927" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "COPD exacerbation or something else? Clinical case" ] ] "contieneResumen" => array:2 [ "pt" => true "en" => true ] "contienePdf" => array:1 [ "pt" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Paulo Gouveia, Arnaldo Pires, Frederica Coimbra, Isabel Trindade, Carlos Capela, Guilherme Gomes, Abel Rua" "autores" => array:7 [ 0 => array:2 [ "nombre" => "Paulo" "apellidos" => "Gouveia" ] 1 => array:2 [ "nombre" => "Arnaldo" "apellidos" => "Pires" ] 2 => array:2 [ "nombre" => "Frederica" "apellidos" => "Coimbra" ] 3 => array:2 [ "nombre" => "Isabel" "apellidos" => "Trindade" ] 4 => array:2 [ "nombre" => "Carlos" "apellidos" => "Capela" ] 5 => array:2 [ "nombre" => "Guilherme" "apellidos" => "Gomes" ] 6 => array:2 [ "nombre" => "Abel" "apellidos" => "Rua" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511509701629?idApp=UINPBA00004E" "url" => "/21735115/0000001500000005/v1_201305151515/S2173511509701629/v1_201305151515/pt/main.assets" ] "pt" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Caso Clínico</span>" "titulo" => "Granulomatose de Wegener – Envolvimento otológico, nasal, laringotraqueal e pulmonar" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "929" "paginaFinal" => "935" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Sandra Figueiredo, Laurentino Mendes Leal, António Morais, Adriana Magalhães, Teresa Oliveira, Venceslau Hespanhol, Carlos Dias, Gabriela Fernandes" "autores" => array:8 [ 0 => array:4 [ "nombre" => "Sandra" "apellidos" => "Figueiredo" "email" => array:1 [ 0 => "sandrabugalho@iol.pt" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Laurentino Mendes" "apellidos" => "Leal" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "António" "apellidos" => "Morais" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "Adriana" "apellidos" => "Magalhães" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff4" ] ] ] 4 => array:3 [ "nombre" => "Teresa" "apellidos" => "Oliveira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">5</span>" "identificador" => "aff0020" ] ] ] 5 => array:3 [ "nombre" => "Venceslau" "apellidos" => "Hespanhol" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff4" ] ] ] 6 => array:3 [ "nombre" => "Carlos" "apellidos" => "Dias" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">6</span>" "identificador" => "aff0025" ] ] ] 7 => array:3 [ "nombre" => "Gabriela" "apellidos" => "Fernandes" "referencia" => array:4 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0015" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff4" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">5</span>" "identificador" => "aff0020" ] 3 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">6</span>" "identificador" => "aff0025" ] ] ] ] "afiliaciones" => array:6 [ 0 => array:3 [ "entidad" => "Internato Médico. Serviço de Pneumologia)" "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Internato Médico. Serviço de Otorrinolaringologia" "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Assistente Hospitalar. Serviço de Pneumologia" "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Assistente Hospitalar Graduado. Serviço de Pneumologia" "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff4" ] 4 => array:3 [ "entidad" => "Assistente Hospitalar Graduada. Unidade de Cuidados Intensivos Polivalentes" "etiqueta" => "<span class="elsevierStyleSup">5</span>" "identificador" => "aff0020" ] 5 => array:3 [ "entidad" => "Assistente Hospitalar Graduado. Serviço de Medicina Intern" "etiqueta" => "<span class="elsevierStyleSup">6</span>" "identificador" => "aff0025" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Hospital de São João (EPE), Porto." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Wegener granulomatosis – Otologic, nasal, tracheobronchial and pulmonary involvement" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-12-22" "fechaAceptado" => "2009-03-05" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec160374" "palabras" => array:2 [ 0 => "Granulomatose de Wegener" 1 => "forma limitada grave" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec160375" "palabras" => array:2 [ 0 => "Wegener¿s granulomatosis" 1 => "severe limited form" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A granulomatose de Wegener é uma vasculite sistémica rara e idiopática caracterizada pelo atingimento dos pequenos vasos. A doença atinge, preferencialmente, as vias aérea superior e inferior e os rins, levando à formação de granulomas e necrose destes órgãos. As manifestações clínicas e o envolvimento orgânico variam largamente. O diagnóstico e tratamento precoce podem levar à recuperação total. No entanto, o atraso no diagnóstico pode ser fatal. Os autores apresentam o caso de uma doente de 33 anos com uma forma de apresentação grave e rara da doença, mas com uma evolução favorável após diagnóstico e tratamento adequado.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Wegener granulomatosis is a rare systemic idiopathic disease characterized by involvement of small vessels – medium and small arteries, venules, arterioles and ocasionally large arteries. This disease has predilection for the upper and lower respiratory tract and the kidney, with granulomatous inflamation and necrosis. Clinical manifestations and organ involvement of the disease vary widely. Early diagnosis and treatment may lead to a full recovery. Without treatment, Wegener's granulomatosis can be fatal. The authors present a case of a 33 year-old female, with severe disease, but with good outcome, after adequate diagnosis and treatment.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:24 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Uber generalisierte septische Gefässerkrankungen" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "F. Wegener" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Verh Dtsch Ges Pathol" "fecha" => "1936" "volumen" => "29" "paginaInicial" => "202" "paginaFinal" => "210" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Necrotizing granulomatosis and angiitis of the lungs" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R. Fienberg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Clin Pathol" "fecha" => "1953" "volumen" => "23" "paginaInicial" => "413" "paginaFinal" => "428" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13040300" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Limited forms of angiitis and granulomatosis of Wegener's type" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C.B. Carrington" 1 => "M. Liebow" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Med" "fecha" => "1966" "volumen" => "41" "paginaInicial" => "497" "paginaFinal" => "527" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5923596" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The concept of limited forms of Wegener's granulomatosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.M. Cassan" 1 => "D.T. Coles" 2 => "E.G. Harisson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Med" "fecha" => "1970" "volumen" => "49" "paginaInicial" => "366" "paginaFinal" => "379" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4917075" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidemiology of Wegener's granulomatosis in Nothern Norway" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "W. Koldingsnes" 1 => "H. Nossent" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Art Rheum" "fecha" => "2000" "volumen" => "43" "numero" => "11" "paginaInicial" => "2481" "paginaFinal" => "2487" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Wegener's granulomatosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "G.F. Duna" 1 => "C. Galperin" 2 => "G.S. Hoffman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rheum Dis Clin North Am" "fecha" => "1995" "volumen" => "21" "paginaInicial" => "949" "paginaFinal" => "986" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8592744" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A.S. Fauci" 1 => "B.F. Haynes" 2 => "P. Katz" 3 => "S.M. Wolff" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Ann Intern Med" "fecha" => "1983" "volumen" => "98" "numero" => "1" "paginaInicial" => "76" "paginaFinal" => "85" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6336643" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Wegener¿s granulomatosis: studies in eighteen patients and a review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.S. Fauci" 1 => "S.M. Wolf" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Medicine (Baltimore)" "fecha" => "1973" "volumen" => "52" "numero" => "6" "paginaInicial" => "535" "paginaFinal" => "561" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nasal manifestations of rheumatic diseases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "N.S. Jones" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Rheum Dis" "fecha" => "1999" "volumen" => "58" "paginaInicial" => "589" "paginaFinal" => "590" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10491354" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Wegener's granulomatosis presenting as a recurrence of chronic otitis media" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "D.M. Hartl" 1 => "P. Aidan" 2 => "O. Brugière" 3 => "O. Sterkers" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Otol" "fecha" => "1998" "volumen" => "19" "numero" => "1" "paginaInicial" => "54" "paginaFinal" => "60" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary Wegener's granulomatosis. A clinical and imaging study of 77 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.F. Cordier" 1 => "D. Valeyre" 2 => "L. Guillevin" 3 => "R. Loire" 4 => "J.M. Brechot" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1990" "volumen" => "97" "paginaInicial" => "906" "paginaFinal" => "912" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2323259" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Thoracic manifestations of Wegener¿s granulomatosis: CT findings in 30 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "S.K. Lee" 1 => "T.S. Kim" 2 => "K. Fujimoto" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00330-002-1422-2" "Revista" => array:7 [ "tituloSerie" => "Eur Radiol" "fecha" => "2003" "volumen" => "13" "paginaInicial" => "43" "paginaFinal" => "51" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12541109" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0300893211006373" "estado" => "S300" "issn" => "03008932" ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Daum TE, Specks U, Colby TV, Edell ES, Brutinel MW, Prakash UB, DeRemee RA. Tracheobronchial involvement in Wegener's granulomatosis Am J Respir Crit Care Med 151:522-526." ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lebovics RS. Clinical features and therapeutic management of subglottic stenosis in patients with Wegener's granulomatosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:7 [ 0 => "C.A. Langford" 1 => "M.C. Sneller" 2 => "C.W. Hallahan" 3 => "G.S. Hoffman" 4 => "W.A. Kammerer" 5 => "C. Talar-Williams" 6 => "A.S. Fauci" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Arthritis Rheum" "fecha" => "1996" "volumen" => "39" "numero" => "10" "paginaInicial" => "1754" "paginaFinal" => "1760" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8843868" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The antineutrophil cytoplasmic antibody-associatedvasculitides" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P. Seo" 1 => "J.H. Stone" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Am JMed" "fecha" => "2004" "volumen" => "117" "paginaInicial" => "39" ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surgical pathology of the lung in Wegener's granulomatosisReview of 87open lung biopsies from 67 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "W.D. Travis" 1 => "G.S. Hoffman" 2 => "R.Y. Leavitt" 3 => "H.I. Pass" 4 => "A.S. Fauci" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Surg Pathol" "fecha" => "1991" "volumen" => "15" "paginaInicial" => "315" "paginaFinal" => "333" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2006712" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The management of subglottic stenosis in patients with Wegener's granulomatosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:9 [ 0 => "R.S. Lebovics" 1 => "G.S. Hoffman" 2 => "R.Y. Leavitt" 3 => "G.S. Kerr" 4 => "W.D. Travis" 5 => "W. Kammere" 6 => "C. Hallahan" 7 => "M. Rottem" 8 => "A.S. Fauci" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1288/00005537-199212000-00005" "Revista" => array:7 [ "tituloSerie" => "Laryngoscope" "fecha" => "1992" "volumen" => "102" "numero" => "12 Pt 1" "paginaInicial" => "1341" "paginaFinal" => "1345" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1453838" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical features and therapeutic management of subglottic stenosis in patients" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:1 [ 0 => "Laqué Solans" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1177/0961203308089693" "Revista" => array:6 [ "tituloSerie" => "Lupus" "fecha" => "2008" "volumen" => "17" "paginaInicial" => "832" "paginaFinal" => "836" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18755865" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A prospective study of antineutrophil cytoplasmic antibody (c-ANCA) and clinical criteria in diagnosing Wegener's granulomatosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.K. Rao" 1 => "N.B. Allen" 2 => "J.R. Feussner" 3 => "M. Weinberger" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Lancet" "fecha" => "1995 7" "volumen" => "346" "numero" => "8980" "paginaInicial" => "926" "paginaFinal" => "931" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7564726" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nomenclature of systemic vasculitis: the proposal of an international consensus conference" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.C. Jennette" 1 => "R.J. Falk" 2 => "K. Andrassy" 3 => "P.A. Bacon" 4 => "J. Churg" 5 => "W.L. Gross" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arthritis Rheum" "fecha" => "1994" "volumen" => "37" "paginaInicial" => "187" "paginaFinal" => "192" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8129773" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Wegener¿s granulomatosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G.S. Hoffman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Curr Opin Reumathol" "fecha" => "1993" "volumen" => "5" "numero" => "1" "paginaInicial" => "11" "paginaFinal" => "17" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evidence-based treatment of systemic vasculitis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D. Jayne" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rheumatology" "fecha" => "2000" "volumen" => "39" "paginaInicial" => "585" "paginaFinal" => "595" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10888702" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Maintenance Therapy for vasculitis associated with antineutrophil cytoplasmic autoantibodies" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.-S.F. Sanders" 1 => "M.C. Slot" 2 => "C.A. Stegeman" 3 => "D. Jayne" 4 => "N. Rasmussen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM200311203492116" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2003" "volumen" => "349" "paginaInicial" => "2072" "paginaFinal" => "2073" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14627795" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prediction of relapses in PR3-ANCA-associated vasculitis by assessing responses of ANCA titres to treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.-SF. Sanders" 1 => "M.G. Huitma" 2 => "C.G.M. Kallenberg" 3 => "C.A. Stegeman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/rheumatology/kei272" "Revista" => array:7 [ "tituloSerie" => "Rheumatology" "fecha" => "2006" "volumen" => "45" "numero" => "6" "paginaInicial" => "724" "paginaFinal" => "729" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16399845" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "pt" "url" => "/21735115/0000001500000005/v1_201305151515/S2173511509701630/v1_201305151515/pt/main.assets" "Apartado" => array:4 [ "identificador" => "9550" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case Report/Caso Clínico" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001500000005/v1_201305151515/S2173511509701630/v1_201305151515/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511509701630?idApp=UINPBA00004E" ]
Article information
ISSN: 21735115Original language: Portuguese
The statistics are updated each day
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 1 | 0 | 1 |
| 2024 October | 33 | 28 | 61 |
| 2024 September | 28 | 20 | 48 |
| 2024 August | 40 | 31 | 71 |
| 2024 July | 31 | 30 | 61 |
| 2024 June | 19 | 32 | 51 |
| 2024 May | 23 | 34 | 57 |
| 2024 April | 25 | 24 | 49 |
| 2024 March | 19 | 24 | 43 |
| 2024 February | 19 | 27 | 46 |
| 2024 January | 17 | 22 | 39 |
| 2023 December | 15 | 16 | 31 |
| 2023 November | 17 | 24 | 41 |
| 2023 October | 14 | 24 | 38 |
| 2023 September | 25 | 33 | 58 |
| 2023 August | 17 | 16 | 33 |
| 2023 July | 19 | 31 | 50 |
| 2023 June | 17 | 17 | 34 |
| 2023 May | 24 | 29 | 53 |
| 2023 April | 15 | 9 | 24 |
Show all
