Caso Clínico
Granulomatose de Wegener – Envolvimento otológico, nasal, laringotraqueal e pulmonar
Wegener granulomatosis – Otologic, nasal, tracheobronchial and pulmonary involvement
Sandra Figueiredo1,
, Laurentino Mendes Leal2, António Morais3, Adriana Magalhães4, Teresa Oliveira5, Venceslau Hespanhol4, Carlos Dias6, Gabriela Fernandes3,4,5,6
Corresponding author
1 Internato Médico. Serviço de Pneumologia)
2 Internato Médico. Serviço de Otorrinolaringologia
3 Assistente Hospitalar. Serviço de Pneumologia
4 Assistente Hospitalar Graduado. Serviço de Pneumologia
5 Assistente Hospitalar Graduada. Unidade de Cuidados Intensivos Polivalentes
6 Assistente Hospitalar Graduado. Serviço de Medicina Intern
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A doença atinge, preferencialmente, as vias aérea superior e inferior e os rins, levando à formação de granulomas e necrose destes órgãos. As manifestações clínicas e o envolvimento orgânico variam largamente. O diagnóstico e tratamento precoce podem levar à recuperação total. No entanto, o atraso no diagnóstico pode ser fatal. Os autores apresentam o caso de uma doente de 33 anos com uma forma de apresentação grave e rara da doença, mas com uma evolução favorável após diagnóstico e tratamento adequado.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Wegener granulomatosis is a rare systemic idiopathic disease characterized by involvement of small vessels – medium and small arteries, venules, arterioles and ocasionally large arteries. This disease has predilection for the upper and lower respiratory tract and the kidney, with granulomatous inflamation and necrosis. Clinical manifestations and organ involvement of the disease vary widely. Early diagnosis and treatment may lead to a full recovery. Without treatment, Wegener's granulomatosis can be fatal. The authors present a case of a 33 year-old female, with severe disease, but with good outcome, after adequate diagnosis and treatment.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:24 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Uber generalisierte septische Gefässerkrankungen" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "F. 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ISSN: 21735115Original language: Portuguese
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