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Doença pulmonar obstrutiva crónica – Uma revisão
Chronic obstructive pulmonary disease – A review
Artur Laizo1,
Corresponding author
alaizo@oi.com.br

Universidade Presidente Antônio Carlos – Campus VI – Juiz de Fora.
1 Mestre em Cirurgia Geral pela UFMG, intensivista, coordenador do Grupo de Estudos Sobre DPOC (GEDPOC), professor nas disciplinas Primeiros Socorros, Farmacologia e Fundamentos de Pneumologia, dos cursos da área de saúde da Universidade Presidente Antônio Carlos – UNIPAC – campus VI, Juiz de Fora – MG
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        "autoresLista" => "Artur Laizo"
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            "entidad" => "Mestre em Cirurgia Geral pela UFMG&#44; intensivista&#44; coordenador do Grupo de Estudos Sobre DPOC &#40;GEDPOC&#41;&#44; professor nas disciplinas Primeiros Socorros&#44; Farmacologia e Fundamentos de Pneumologia&#44; dos cursos da &#225;rea de sa&#250;de da Universidade Presidente Ant&#244;nio Carlos &#8211; UNIPAC &#8211; campus VI&#44; Juiz de Fora &#8211; MG"
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      "en" => array:1 [
        "titulo" => "Chronic obstructive pulmonary disease &#8211; A review"
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        "titulo" => "Resumo"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A DPOC &#233; uma doen&#231;a preven&#237;vel e trat&#225;vel ocasionada pela exposi&#231;&#227;o ao tabagismo e gases t&#243;xicos&#46; A sua caracter&#237;stica &#233; a obstru&#231;&#227;o progressiva ao fluxo a&#233;reo de irrevers&#237;vel depois de ocorrerem as les&#245;es no par&#234;nquima&#46; O objectivo do trabalho &#233; uma revis&#227;o sistem&#225;tica da doen&#231;a e da forma de tratamento&#46;</p> <span class="elsevierStyleSectionTitle">Discuss&#227;o</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">o tabagismo &#233; a maior causa de DPOC e leva a n&#227;o s&#243; uma diminui&#231;&#227;o da oxigena&#231;&#227;o por hiperinsufla&#231;&#227;o pulmonar com redu&#231;&#227;o do fluxo a&#233;reo como a um processo inflamat&#243;rio sist&#233;mico&#44; reduzindo a resist&#234;ncia &#224; fadiga da musculatura esquel&#233;tica produzindo hipoxemia&#44; diminui&#231;&#227;o do fluxo sangu&#237;neo perif&#233;rico&#44; levando inclusive a abortos espont&#226;neos e partos prematuros&#46; Marcadores inflamat&#243;rios como as interleucinas e o TNF-alfa mant&#234;m o quadro sist&#233;mico&#46; A cessa&#231;&#227;o do tabagismo melhora a hipoxemia&#44; a intoler&#226;ncia ao exerc&#237;cio&#44; por&#233;m n&#227;o recupera o tecido lesado&#46; A DPOC &#233; uma doen&#231;a grave que pode ser evitada se houver uma consciencializa&#231;&#227;o maior da popula&#231;&#227;o a respeito dos malef&#237;cios do cigarro&#46;</p>"
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        "titulo" => "Abstract"
        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">COPD is a preventable and treatable disease caused by exposure to tobacco smoke and poisonous gases&#46; It is characterised by progressive obstruction of the airflow&#44; irreversible once lesions occur in the parenchyma&#46; This article aims to systematically review the disease and its treatment&#46;</p> <span class="elsevierStyleSectionTitle">Discussion</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Smoking is the main cause of COPD and leads to decreased oxygenation via lung hyperinflation with reduced airflow as a systemic inflammatory process&#46; This reduces resistance to fatigue of the skeletal musculature&#44; leading to hypoxemia&#44; decreased peripheral blood flow and also miscarriages and premature births&#46; Inflammatory markers such as interleukins and TNF-alpha maintain the systemic picture&#46; While smoking cessation improves hypoxemia and exercise intolerance&#44; it does not repair damaged tissue&#46; COPD is a serious disease which can be avoided by a wider understanding by the population of the harm smoking causes&#46;</p>"
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Article information
ISSN: 21735115
Original language: Portuguese
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