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Linfangioleiomiomatose – A propósito de três casos clínicos
Lymphangioleiomyomatosis – report of three cases
Carla Valente1,
Corresponding author
carlavalente77@yahoo.com.br

Departamento de Ciências Pneumológicas e Alergológicas dos Hospitais da Universidade de Coimbra Av. Bissaya Barreto e Praceta Prof. Mota Pinto 3000-075 Coimbra.
, Sónia André1, Alexandra Catarino2, Fátima Fradinho2, Fernanda Gamboa2, Mário Loureiro3, M Fontes Baganha4
1 Interna Complementar de Pneumologia/Resident, Pulmonology
2 Assistente Hospitalar de Pneumologia/Consultant, Pulmonology
3 Director do Serviço de Pneumologia dos HUC/Head, Pulomonology Unit, HUC
4 Director do Departamento de Ciências Pneumológicas e Alergológicas dos HUC/Director, Dept. of Pulmonology and Allergological Sciences, HUC
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          "palabras" => array:2 [
            0 => "Linfangioleiomiomatose"
            1 => "complexo esclerose tuberosa"
          ]
        ]
      ]
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            0 => "Lymphangioleiomyomatosis"
            1 => "tuberous sclero sis complex"
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      "pt" => array:2 [
        "titulo" => "Resumo"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A linfangioleiomiomatose &#40;LAM&#41; &#233; uma doen&#231;a rara&#44; de etiologia desconhecida&#44; caracterizada pela prolifera&#231;&#227;o anormal de c&#233;lulas musculares lisas nas regi&#245;es perilinf&#225;tica&#44; perivascular e peribr&#244;nquica&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A LAM pode ocorrer esporadicamente ou associada ao complexo esclerose tuberosa &#40;CET&#41; e hamartose heredit&#225;ria multiorg&#226;nica<span class="elsevierStyleSup">1</span>&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Em ambas as situa&#231;&#245;es a LAM afecta principalmente mulheres jovens em idade f&#233;rtil&#44; sendo que aproximadamente 1&#47;3 das mulheres com CET t&#234;m LAM<span class="elsevierStyleSup">2</span>&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A prop&#243;sito desta patologia&#44; os autores elaboram uma revis&#227;o da literatura e descrevem os casos cl&#237;nicos de tr&#234;s doentes do sexo feminino com o diagn&#243;stico de LAM com base nos achados cl&#237;nicos e imagiol&#243;gicos&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Pulmonary lymphangioleiomyomatosis &#40;LAM&#41; is a rare disease of unknown aetiology&#46; It is characterized by proliferation of abnormal smooth-muscle cells throughout the peribronchial&#44; perivascular and perilymphatic regions of the lung&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">LAM may occur sporadically&#44; in association with tuberous sclerosis complex &#40;TSC&#41; or inheritable multiorgan hamartomatosis <span class="elsevierStyleSup">1</span>&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">In either situation&#44; LAM occurs almost exclusively in women of reproductive age&#44; and approximately one third of the patients with TSC have LAM2&#46; The authors review the cases of three female patients diagnosed with LAM based on clinical and radiological findings&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">A brief review of the disease is then presented&#46;</p>"
      ]
    ]
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Article information
ISSN: 21735115
Original language: Portuguese
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