Hemangioendotelioma epitelióide da pleura – Uma apresentação rara a propósito de um caso clínico
Epithelioid hemangioendothelioma of the pleura – A rare presentation of a clinical case
Sónia André1,
, Carla Valente1,6, Benedita Paiva2,6, Alice Pêgo3,6, Lina Carvalho4,6, A. Segorbe Luís5,6
Corresponding author
1 Interna do Internato Complementar de Pneumologia
2 Assistente Hospitalar de Pneumologia
3 Assistente Graduada de Pneumologia
4 Professora de Anatomia Patológica da FMUC e Chefe de Serviço de Anatomia Patológica dos HUC
5 Professor de Pneumologia da FMUC e Chefe de Serviço de Pneumologia dos HUC
6 Faculdade de Medicina, Universidade de Coimbra, Departamento de Ciências Pneumológicas e Alergológicas dos Hospitais da Universidade de Coimbra, Av. Bissaya Barreto e Praceta Prof. Mota Pinto, 3000-075 Coimbra
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Bissaya Barreto e Praceta Prof. Mota Pinto, 3000-075 Coimbra" "etiqueta" => "<span class="elsevierStyleSup">6</span>" "identificador" => "aff0030" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondência." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Epithelioid hemangioendothelioma of the pleura – A rare presentation of a clinical case" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-09-02" "fechaAceptado" => "2009-10-08" "PalabrasClave" => array:2 [ "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec160832" "palabras" => array:3 [ 0 => "Hemangioendotelioma" 1 => "tumor vascular" 2 => "pleura" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec160831" "palabras" => array:3 [ 0 => "Haemangioendotelioma" 1 => "vascular tumour" 2 => "pleura" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">O hemangioendotelioma epitelióide (HEE) é um tumor de origem vascular, de grau intermédio de malignidade, cuja apresentação primária na pleura é rara. Pelo reduzido número de casos descritos na literatura, os autores apresentam o caso de uma doente de 65 anos, que recorreu ao serviço de urgência por toracalgia à direita, com sete meses de evolução, na sequência de um traumatismo torácico. Radiologicamente apresentava sinais sugestivos de derrame pleural direito de volume moderado. A biópsia pleuropulmonar, efectuada por toracotomia, permitiu estabelecer o diagnóstico histológico de HEE da pleura.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Atendendo ao estádio localmente avançado do tumor, a doente iniciou quimioterapia com carboplatina e etoposido, tendo falecido 6 meses após o diagnóstico. Constata-se, com este caso, que a manifestação pleural do HEE tem um comportamento agressivo, semelhante ao do angiossarcoma, com uma sobrevida de apenas alguns meses após o diagnóstico.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Epithelioid Hemangioendothelioma (EHE) is a vascular tumour with rare pleural presentation. As there are a small number of cases described in the literature the authors present the case of a 65-year-old woman, who was admitted to the Emergency Department for a right-sided chest pain, which progressed over 7 months, after a thoracic trauma. The chest X-ray showed signs of a moderate right-sided pleural effusion. A pleural-pulmonary biopsy carried out by toracotomy established the histological diagnosis of EHE of the pleura.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Due to the locally advanced stage of the tumour, chemotherapy with carboplatin and etoposide was prescribed and the patient died 6 months later.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">This case confirms that pleural EHE has an aggressive behaviour, similar to an angiossarcoma, with a median survival of only a few months after diagnosis.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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ISSN: 21735115Original language: Portuguese
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