Pertussis in Portugal – Time for a new strategy
Pertussis em Portugal – A importância de uma nova estratégia vacinal
Susana Gama de Sousa1,
, Henrique Barros2, Doutor Henrique Barros3
Corresponding author
susana.gama@chma.min_saude.pt
susanagamasousa@gmail.com
Correspondence to/Correspondência: Serviço de Pediatria Centro Hospitalar Médio Ave – Unidade de Famalicão Rua Cupertino de Miranda, s/n Apartado 31 4764-958 Vila Nova de Famalicão, Telef: (+351) 252300800.
susanagamasousa@gmail.com
Correspondence to/Correspondência: Serviço de Pediatria Centro Hospitalar Médio Ave – Unidade de Famalicão Rua Cupertino de Miranda, s/n Apartado 31 4764-958 Vila Nova de Famalicão, Telef: (+351) 252300800.
1 Pediatra, Serviço de Higiene e Epidemiologia, Instituto Superior de Saúde Pública – Faculdade de Medicina da Universidade do Porto, Porto e Serviço de Pediatria, Centro Hospitalar Médio Ave, Famalicão, Portugal/Pediatrician
2 Prof. Catedrático e Director do Serviço de Higiene e Epidemiologia, Instituto de Saúde Pública – Faculdade de Medicina da Universidade do Porto, Porto, Portugal
3 Serviço de Higiene e Epidemiologia Instituto de Saúde Pública – Faculdade de Medicina da Universidade do Porto, Porto, Portugal
Read
1042
Timeswas read the article
505
Total PDF
537
Total HTML
Share statistics
array:24 [ "pii" => "S2173511510700609" "issn" => "21735115" "doi" => "10.1016/S2173-5115(10)70060-9" "estado" => "S300" "fechaPublicacion" => "2010-07-01" "aid" => "70060" "copyright" => "Sociedade Portuguesa de Pneumologia" "copyrightAnyo" => "2010" "documento" => "article" "crossmark" => 0 "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "rev" "cita" => "Rev Port Pneumol. 2010;16:573-88" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2837 "formatos" => array:3 [ "EPUB" => 222 "HTML" => 1583 "PDF" => 1032 ] ] "itemSiguiente" => array:19 [ "pii" => "S2173511510700610" "issn" => "21735115" "doi" => "10.1016/S2173-5115(10)70061-0" "estado" => "S300" "fechaPublicacion" => "2010-07-01" "aid" => "70061" "copyright" => "Sociedade Portuguesa de Pneumologia" "documento" => "article" "crossmark" => 0 "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "rev" "cita" => "Rev Port Pneumol. 2010;16:589-606" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 5422 "formatos" => array:3 [ "EPUB" => 229 "HTML" => 2403 "PDF" => 2790 ] ] "pt" => array:10 [ "idiomaDefecto" => true "titulo" => "Ecografia na patologia torácica" "tienePdf" => "pt" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "pt" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "589" "paginaFinal" => "606" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Ultrasound in chest disease" ] ] "contieneResumen" => array:2 [ "pt" => true "en" => true ] "contienePdf" => array:1 [ "pt" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "António Bugalho, Júlio Semedo, João Alpendre, José Cepeda Ribeiro, Luís Carreiro" "autores" => array:5 [ 0 => array:2 [ "nombre" => "António" "apellidos" => "Bugalho" ] 1 => array:2 [ "nombre" => "Júlio" "apellidos" => "Semedo" ] 2 => array:2 [ "nombre" => "João" "apellidos" => "Alpendre" ] 3 => array:2 [ "nombre" => "José" "apellidos" => "Cepeda Ribeiro" ] 4 => array:2 [ "nombre" => "Luís" "apellidos" => "Carreiro" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511510700610?idApp=UINPBA00004E" "url" => "/21735115/0000001600000004/v1_201305151531/S2173511510700610/v1_201305151531/pt/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2173511510700592" "issn" => "21735115" "doi" => "10.1016/S2173-5115(10)70059-2" "estado" => "S300" "fechaPublicacion" => "2010-07-01" "aid" => "70059" "copyright" => "Sociedade Portuguesa de Pneumologia" "documento" => "article" "crossmark" => 0 "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "rev" "cita" => "Rev Port Pneumol. 2010;16:559-72" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 5813 "formatos" => array:3 [ "EPUB" => 217 "HTML" => 2499 "PDF" => 3097 ] ] "pt" => array:10 [ "idiomaDefecto" => true "titulo" => "Abordagem terapêutica da tuberculose e resolução de alguns problemas associados à medicação" "tienePdf" => "pt" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "pt" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "559" "paginaFinal" => "572" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Tuberculosis treatment and management of some Sproblems related to the medication" ] ] "contieneResumen" => array:2 [ "pt" => true "en" => true ] "contienePdf" => array:1 [ "pt" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "R. Duarte, A. Carvalho, D. Ferreira, S. Saleiro, R. Lima, M. Mota, E. Raymundo, M. Villar, A. Correia" "autores" => array:9 [ 0 => array:2 [ "nombre" => "R." "apellidos" => "Duarte" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Carvalho" ] 2 => array:2 [ "nombre" => "D." "apellidos" => "Ferreira" ] 3 => array:2 [ "nombre" => "S." "apellidos" => "Saleiro" ] 4 => array:2 [ "nombre" => "R." "apellidos" => "Lima" ] 5 => array:2 [ "nombre" => "M." "apellidos" => "Mota" ] 6 => array:2 [ "nombre" => "E." "apellidos" => "Raymundo" ] 7 => array:2 [ "nombre" => "M." "apellidos" => "Villar" ] 8 => array:2 [ "nombre" => "A." "apellidos" => "Correia" ] ] ] ] ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511510700592?idApp=UINPBA00004E" "url" => "/21735115/0000001600000004/v1_201305151531/S2173511510700592/v1_201305151531/pt/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "titulo" => "Pertussis in Portugal – Time for a new strategy" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "573" "paginaFinal" => "588" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Susana Gama de Sousa, Henrique Barros, Doutor Henrique Barros" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Susana Gama" "apellidos" => "de Sousa" "email" => array:2 [ 0 => "susana.gama@chma.min_saude.pt" 1 => "susanagamasousa@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Henrique" "apellidos" => "Barros" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Doutor" "apellidos" => "Henrique Barros" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Pediatra, Serviço de Higiene e Epidemiologia, Instituto Superior de Saúde Pública – Faculdade de Medicina da Universidade do Porto, Porto e Serviço de Pediatria, Centro Hospitalar Médio Ave, Famalicão, Portugal/Pediatrician" "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Prof. Catedrático e Director do Serviço de Higiene e Epidemiologia, Instituto de Saúde Pública – Faculdade de Medicina da Universidade do Porto, Porto, Portugal" "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Serviço de Higiene e Epidemiologia Instituto de Saúde Pública – Faculdade de Medicina da Universidade do Porto, Porto, Portugal" "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondence to/Correspondência: Serviço de Pediatria Centro Hospitalar Médio Ave – Unidade de Famalicão Rua Cupertino de Miranda, s/n Apartado 31 4764-958 Vila Nova de Famalicão, Telef: (+351) 252300800." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Pertussis em Portugal – A importância de uma nova estratégia vacinal" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-06-29" "fechaAceptado" => "2010-01-07" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec160895" "palabras" => array:5 [ 0 => "Bordetella pertussis" 1 => "pertussis" 2 => "vaccination" 3 => "Portugal" 4 => "mathematical models" ] ] ] "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec160894" "palabras" => array:5 [ 0 => "Tosse convulsa" 1 => "coqueluche" 2 => "Bordetella pertussis" 3 => "vacinação" 4 => "modelos matemáticos" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The introduction of routine vaccination against <span class="elsevierStyleItalic">Bordetella pertussis</span> led to a drastic decline in the number of reported cases of pertussis. Nevertheless, a gradual increase in pertussis notifications has been observed in the last years, and political vaccination changes have been conducted in some countries. Pertussis epidemiology is reviewed, taking into account mathematical models studies concerning new vaccinal strategies for pertussis prevention and new international recommendations. Regarding Portugal, the need for a “booster” in adolescence is emphasized, and other recommendations for pertussis control are suggested.</p>" ] "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A introdução da vacina antipertussis nos programas de vacinação originou uma diminuição drástica da incidência de tosse convulsa no mundo. No entanto, nos últimos anos tem-se observado um aumento gradual do número de notificações, facto que já levou vários países a reformularem estratégias vacinais para esta doença. Foi efectuada uma revisão epidemiológica da tosse convulsa, realçando estudos baseados em modelos matemáticos que tentam prever o impacto de novas estratégias vacinais e novas recomendações internacionais. Tendo em conta a realidade portuguesa, alerta-se para a necessidade de um reforço vacinal na idade da adolescência e sugerem-se outras recomendações para um melhor controlo da tosse convulsa no nosso país.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliography/Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:40 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pertussis – United States January 1992–June 1995" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Centers for Disease Control and Prevention" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "MMWR" "fecha" => "1995" "volumen" => "44" "paginaInicial" => "525" "paginaFinal" => "529" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7603428" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increase in deaths from pertussis among young infants in the United States in the 1990s" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C.R. Vitek" 1 => "F.B. Pascual" 2 => "A.L. Baughman" 3 => "T.V. Murphy" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.inf.0000073266.30728.0e" "Revista" => array:7 [ "tituloSerie" => "Pediatr Infect Dis J" "fecha" => "2003" "volumen" => "22" "numero" => "7" "paginaInicial" => "628" "paginaFinal" => "634" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12867839" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "World Health Organization. WHO position paper on pertussis (January 2005). (<a class="elsevierStyleInterRef" href="http://www.who.int/">www.who.int/</a>) Accessed June 2009." ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Outcomes of <span class="elsevierStyleItalic">Bordetella pertussis</span> infection in different age groups of an immunized population" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "Q. He" 1 => "M.K. Viljanen" 2 => "S. Nikkari" 3 => "R. Lyytikainen" 4 => "J. Mertsola" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Infect Dis" "fecha" => "1994" "volumen" => "170" "numero" => "4" "paginaInicial" => "873" "paginaFinal" => "877" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7930729" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Duration of effectiveness of pertussis vaccine: evidence from a 10 year community study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D. Jenkinson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br Med J (Clin Res Ed)" "fecha" => "1988" "volumen" => "296" "numero" => "6622" "paginaInicial" => "612" "paginaFinal" => "614" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pertussis outbreak in an elementary school with high vaccination coverage" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "N. Khetsuriani" 1 => "K. Bisgard" 2 => "D.R. Prevots" 3 => "M. Brennan" 4 => "M. Wharton" 5 => "S. Pandya" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Pediatr Infect Dis J" "fecha" => "2001" "volumen" => "20" "numero" => "12" "paginaInicial" => "1108" "paginaFinal" => "1112" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11740314" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High prevalence of antibody titers against Bordetella pertussis in an adult population with prolonged cough" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A.M. Kapaskelis" 1 => "E.K. Vouloumanou" 2 => "E.K. Rafailidis" 3 => "P. Hatzoupoulou" 4 => "D. Nikita" 5 => "M.E. Falagas" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Resp Med" "fecha" => "2008" "volumen" => "102" "paginaInicial" => "1586" "paginaFinal" => "1591" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Population based incidence of pertussis among adolescents and adults Minnesota 1995–1996" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P. Strebel" 1 => "J. Nordin" 2 => "K. Edwards" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/319853" "Revista" => array:6 [ "tituloSerie" => "J Infect Dis" "fecha" => "2001" "volumen" => "183" "paginaInicial" => "1353" "paginaFinal" => "1359" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11294666" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neonatal vaccination with acellular pertussis vaccine accelerates the acquisition of pertussis antibodies in infants" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:8 [ 0 => "M. Knuf" 1 => "H.J. Schmitt" 2 => "J. Wolter" 3 => "L. Schuerman" 4 => "J.M. Jacquet" 5 => "D. Kieninger" 6 => "C.A. Siegrist" 7 => "F. Zepp" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jpeds.2007.09.034" "Revista" => array:7 [ "tituloSerie" => "J Pediatr" "fecha" => "2008" "volumen" => "152" "numero" => "5" "paginaInicial" => "655" "paginaFinal" => "660" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18410769" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Infectious diseases of humans: dynamics and control" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.M.M.R. Anderson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:2 [ "fecha" => "1991" "editorial" => "Oxford Science Publications" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The science and fiction of the “resurgence” of pertussis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.D. Cherry" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Pediatrics" "fecha" => "2003" "volumen" => "112" "numero" => "2" "paginaInicial" => "405" "paginaFinal" => "406" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12897292" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pertussis vaccine" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.D. KM Edwards" 1 => "E.A. Mortimer Jr." ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "edicion" => "3rd" "fecha" => "1999" "editorial" => "W.B. Saunders" "editorialLocalizacion" => "Philadelphia" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Whooping cough makes global comeback" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P. Das" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet Infect Dis" "fecha" => "2002" "volumen" => "2" "numero" => "6" "paginaInicial" => "322" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12144890" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pertussis resurgence in Canada largely caused by a cohort effect" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B. Ntezayabo" 1 => "G. De Serres" 2 => "B. Duval" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.inf.0000045220.82991.5a" "Revista" => array:8 [ "tituloSerie" => "Pediatr Infect Dis J" "fecha" => "2003" "volumen" => "22" "numero" => "1" "paginaInicial" => "22" "paginaFinal" => "27" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12544404" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S021057051200088X" "estado" => "S300" "issn" => "02105705" ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adaptation of <span class="elsevierStyleItalic">Bordetella pertussis</span> to vaccination: a cause for its reemergence?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "F.R. Mooi" 1 => "I.H. van Loo" 2 => "A.J. King" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3201/eid0707.010708" "Revista" => array:7 [ "tituloSerie" => "Emerg Infect Dis" "fecha" => "2001" "volumen" => "7" "numero" => "3 Suppl" "paginaInicial" => "526" "paginaFinal" => "528" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11485646" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Thirty-five years’ experience with the whole-cell pertussis vaccine in France: vaccine strains analysis and immunogenicity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E. Njamkepo" 1 => "F. Rimlinger" 2 => "S. Thiberge" 3 => "N. Guiso" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Vaccine" "fecha" => "2002" "volumen" => "20" "numero" => "9–10" "paginaInicial" => "1290" "paginaFinal" => "1294" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11818147" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Shifts of <span class="elsevierStyleItalic">Bordetella pertussis</span> variants in Sweden from 1970 to 2003, during three periods marked by different vaccination programs" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H.O. Hallander" 1 => "A. Advani" 2 => "D. Donnelly" 3 => "L. Gustafsson" 4 => "R.M. Carlsson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1128/JCM.43.6.2856-2865.2005" "Revista" => array:7 [ "tituloSerie" => "J Clin Microbiol" "fecha" => "2005" "volumen" => "43" "numero" => "6" "paginaInicial" => "2856" "paginaFinal" => "2865" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15956409" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Large-scale comparative analysis of pertussis population dynamics: periodicity, synchrony, and impact of vaccination" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H. Broutin" 1 => "J.F. Guegan" 2 => "E. Elguero" 3 => "F. Simondon" 4 => "B. Cazelles" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/aje/kwi141" "Revista" => array:7 [ "tituloSerie" => "Am J Epidemiol" "fecha" => "2005" "volumen" => "161" "numero" => "12" "paginaInicial" => "1159" "paginaFinal" => "1167" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15937025" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Trends in pertussis among infants in the United States, 1980–1999" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Tanaka" 1 => "C.R. Vitek" 2 => "F.B. Pascual" 3 => "K.M. Bisgard" 4 => "J.E. Tate" 5 => "T.V. Murphy" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/jama.290.22.2968" "Revista" => array:7 [ "tituloSerie" => "Jama" "fecha" => "2003" "volumen" => "290" "numero" => "22" "paginaInicial" => "2968" "paginaFinal" => "2975" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14665658" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pertussis in adults: frequency of transmission after household exposure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C.H. Wirsing von Konig" 1 => "S. Postels-Multani" 2 => "H.L. Bock" 3 => "H.J. Schmitt" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Lancet" "fecha" => "1995" "volumen" => "346" "numero" => "8986" "paginaInicial" => "1326" "paginaFinal" => "1329" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7475771" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Return of epidemic pertussis in the United States" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.W. Bass" 1 => "R.R. Wittler" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:8 [ "tituloSerie" => "Pediatr Infect Dis J" "fecha" => "1994" "volumen" => "13" "numero" => "5" "paginaInicial" => "343" "paginaFinal" => "345" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8072813" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S1542356508002425" "estado" => "S300" "issn" => "15423565" ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "An adult formulation of a five-component acellular pertussis vaccine combined with diphtheria and tetanus toxoids is safe and immunogenic in adolescents and adults" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S.A. Halperin" 1 => "B. Smith" 2 => "M. Russell" 3 => "P. Hasselback" 4 => "R. Guasparini" 5 => "D. Skowronski" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Vaccine" "fecha" => "2000" "volumen" => "18" "numero" => "14" "paginaInicial" => "1312" "paginaFinal" => "1319" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10618527" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acellular vaccines containing reduced quantities of pertussis antigens as a booster in adolescents" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "N.N. Tran Minh" 1 => "Q. He" 2 => "A. Ramalho" 3 => "A. Kaufhold" 4 => "M.K. Viljanen" 5 => "H. Arvilommi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Pediatrics" "fecha" => "1999" "volumen" => "104" "numero" => "6" "paginaInicial" => "e70" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10586004" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S188898911100111X" "estado" => "S300" "issn" => "18889891" ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A randomized trial of two acellular pertussis vaccines (dTpa and pa) and a licensed diphtheria-tetanus vaccine (Td) in adults" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "F.M. Turnbull" 1 => "T.C. Heath" 2 => "B.B. Jalaludin" 3 => "M.A. Burgess" 4 => "A.C. Ramalho" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:8 [ "tituloSerie" => "Vaccine" "fecha" => "2000" "volumen" => "19" "numero" => "6" "paginaInicial" => "628" "paginaFinal" => "636" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11090714" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S1699258X08724641" "estado" => "S300" "issn" => "1699258X" ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Is pertussis a frequent cause of cough in adolescents and adults? Should routine pertussis immunization be recommended?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "K.M. Edwards" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/320762" "Revista" => array:7 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "2001" "volumen" => "32" "numero" => "12" "paginaInicial" => "1698" "paginaFinal" => "1699" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11360209" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adolescent and adult pertussis vaccination: computer simulations of five new strategies" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Van Rie" 1 => "H.W. Hethcote" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.vaccine.2004.01.067" "Revista" => array:7 [ "tituloSerie" => "Vaccine" "fecha" => "2004" "volumen" => "22" "numero" => "23–24" "paginaInicial" => "3154" "paginaFinal" => "3165" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15297068" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Two primary doses of diphtheria–tetanus–acellular pertussis vaccine induce immunological responses to <span class="elsevierStyleItalic">Bordetella pertussis</span> as strong as those induced by three primary doses" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "T. Tomoda HOaTK" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Vaccine" "fecha" => "1997" "volumen" => "15" "paginaInicial" => "1955" "paginaFinal" => "1958" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9413107" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Using computer simulations to compare pertussis vaccination strategies in Australia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "H.W. Hethcote" 1 => "P. Horby" 2 => "P. McIntyre" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.vaccine.2003.11.053" "Revista" => array:8 [ "tituloSerie" => "Vaccine" "fecha" => "2004" "volumen" => "22" "numero" => "17–18" "paginaInicial" => "2181" "paginaFinal" => "2191" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15149775" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S1699258X09001910" "estado" => "S300" "issn" => "1699258X" ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sustained efficacy during the first 6 years of life of 3-component acellular pertussis vaccines administered in infancy: the Italian experience" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Salmaso" 1 => "P. Mastrantonio" 2 => "A.E. Tozzi" 3 => "P. Stefanelli" 4 => "A. Anemona" 5 => "M.L. Ciofi degli Atti" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "2001" "volumen" => "108" "numero" => "5" "paginaInicial" => "E81" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11694665" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A modelling analysis of pertussis transmission and vaccination in Rio de Janeiro" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P.M. Luz" 1 => "C.T. Codeco" 2 => "G.L. Werneck" 3 => "C.J. Struchiner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Brazil. Epidemiol Infect" "fecha" => "2006" "volumen" => "134" "numero" => "4" "paginaInicial" => "850" "paginaFinal" => "862" ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib31" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New pertussis vaccination strategies beyond infancy: recommendations by the global pertussis initiative" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K.D. Forsyth" 1 => "M. Campins-Marti" 2 => "J. Caro" 3 => "J.D. Cherry" 4 => "D. Greenberg" 5 => "N. Guiso" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/426020" "Revista" => array:7 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "2004" "volumen" => "39" "numero" => "12" "paginaInicial" => "1802" "paginaFinal" => "1809" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15578403" "web" => "Medline" ] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib32" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevention of pertussis: recommendations derived from the second Global Pertussis Initiative roundtable meeting" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "K.D. Forsyth" 1 => "C.H. Wirsing von Konig" 2 => "T. Tan" 3 => "J. Caro" 4 => "S. Plotkin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.vaccine.2006.12.017" "Revista" => array:7 [ "tituloSerie" => "Vaccine" "fecha" => "2007" "volumen" => "25" "numero" => "14" "paginaInicial" => "2634" "paginaFinal" => "2642" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17280745" "web" => "Medline" ] ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib33" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Ministério da Saúde, Portugal. Direcção-Geral de Saude. Circular Normativa n.° 08/DT de 21.12.2005. Plano Nacional de Vacinação 2006 (Orientações técnicas n.° 10) Accessed June 2009.(<a class="elsevierStyleInterRef" href="http://www.dgs.pt/">www.dgs.pt/</a>)." ] ] ] 33 => array:3 [ "identificador" => "bib34" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adult formulation of a five component acellular pertussis vaccine combined with diphtheria and tetanus toxoids and inactivated poliovirus vaccine is safe and immunogenic in adolescents and adults" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S.A. Halperin" 1 => "B. Smith" 2 => "M. Russell" 3 => "D. Scheifele" 4 => "E. Mills" 5 => "P. Hasselback" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Pediatr Infect Dis J" "fecha" => "2000" "volumen" => "19" "numero" => "4" "paginaInicial" => "276" "paginaFinal" => "283" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10783014" "web" => "Medline" ] ] ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib35" "etiqueta" => "35." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The EUVAC-NET survey: national pertussis surveillance systems in the European Union, Switzerland Norway, and Iceland" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.E. Schmidt" 1 => "A.E. Tozzi" 2 => "L. Rava" 3 => "S. Glismann" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Euro Surveill" "fecha" => "2001" "volumen" => "6" "numero" => "6" "paginaInicial" => "98" "paginaFinal" => "104" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11675537" "web" => "Medline" ] ] ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib36" "etiqueta" => "36." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diphtheria, pertussis, and measles in Portugal before and after mass vaccination: a time series analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M.C. Gomes" 1 => "J.J. Gomes" 2 => "A.C. Paulo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Eur J Epidemiol" "fecha" => "1999" "volumen" => "15" "numero" => "9" "paginaInicial" => "791" "paginaFinal" => "798" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10608357" "web" => "Medline" ] ] ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib37" "etiqueta" => "37." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunisation coverage in the European Union" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "N. Guerin" 1 => "C. Roure" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Euro Surveill" "fecha" => "1997" "volumen" => "2" "numero" => "1" "paginaInicial" => "2" "paginaFinal" => "4" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12631831" "web" => "Medline" ] ] ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib38" "etiqueta" => "38." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Resurgence of pertussis in northern Portugal: two severe cases in very young children" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G. Goncalves" 1 => "E. Machado" 2 => "E. Gouveia" 3 => "M.A. Santos" 4 => "L. Castro" 5 => "R. Aguas" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Euro Surveill" "fecha" => "2005" "volumen" => "10" "numero" => "6" ] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib39" "etiqueta" => "39." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Ministério da Saúde, Portugal. Direcção de Serviços de Epidemiologia e Estatisticas da Saúde. Doenças de Declaração Obrigatória. 2008, Lisboa. Accessed June 2009.(<a class="elsevierStyleInterRef" href="http://www.dgs.pt/">www.dgs.pt/</a>)" ] ] ] 39 => array:3 [ "identificador" => "bib40" "etiqueta" => "40." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluation of strategies for use of acellular pertussis vaccine in adolescents and adults: a cost-benefit analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "K.W. Purdy" 1 => "J.W. Hay" 2 => "M.F. Botteman" 3 => "J.I. Ward" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/421091" "Revista" => array:7 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "2004" "volumen" => "39" "numero" => "1" "paginaInicial" => "20" "paginaFinal" => "28" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15206048" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735115/0000001600000004/v1_201305151531/S2173511510700609/v1_201305151531/en/main.assets" "Apartado" => array:4 [ "identificador" => "9551" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Review Article/Artigo de Revisão" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001600000004/v1_201305151531/S2173511510700609/v1_201305151531/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511510700609?idApp=UINPBA00004E" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 5 | 1 | 6 |
| 2024 October | 32 | 32 | 64 |
| 2024 September | 34 | 25 | 59 |
| 2024 August | 44 | 31 | 75 |
| 2024 July | 33 | 38 | 71 |
| 2024 June | 21 | 36 | 57 |
| 2024 May | 28 | 30 | 58 |
| 2024 April | 30 | 31 | 61 |
| 2024 March | 20 | 24 | 44 |
| 2024 February | 26 | 20 | 46 |
| 2024 January | 34 | 25 | 59 |
| 2023 December | 26 | 25 | 51 |
| 2023 November | 22 | 24 | 46 |
| 2023 October | 20 | 34 | 54 |
| 2023 September | 44 | 25 | 69 |
| 2023 August | 34 | 26 | 60 |
| 2023 July | 22 | 33 | 55 |
| 2023 June | 13 | 13 | 26 |
| 2023 May | 24 | 24 | 48 |
| 2023 April | 25 | 8 | 33 |
Show all
