Correspondence to/Correspondência: Departamento de Pediatria. Hospital de Santa Maria, Av. Professor. Egas Moniz, 1649-035 Lisboa.
was read the article
array:24 [ "pii" => "S2173511510700774" "issn" => "21735115" "doi" => "10.1016/S2173-5115(10)70077-4" "estado" => "S300" "fechaPublicacion" => "2010-09-01" "aid" => "70077" "copyright" => "Sociedade Portuguesa de Pneumologia" "copyrightAnyo" => "2010" "documento" => "article" "crossmark" => 0 "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "fla" "cita" => "Rev Port Pneumol. 2010;16:779-95" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 4382 "formatos" => array:3 [ "EPUB" => 241 "HTML" => 2844 "PDF" => 1297 ] ] "itemSiguiente" => array:19 [ "pii" => "S2173511510700786" "issn" => "21735115" "doi" => "10.1016/S2173-5115(10)70078-6" "estado" => "S300" "fechaPublicacion" => "2010-09-01" "aid" => "70078" "copyright" => "Sociedade Portuguesa de Pneumologia" "documento" => "article" "crossmark" => 0 "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "fla" "cita" => "Rev Port Pneumol. 2010;16:797-808" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3230 "formatos" => array:3 [ "EPUB" => 219 "HTML" => 1936 "PDF" => 1075 ] ] "en" => array:10 [ "idiomaDefecto" => true "titulo" => "The Influence of an undergraduate scientific initiation programme onn the professional profile of new physicians" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "pt" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "797" "paginaFinal" => "808" ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Influência de um programa de iniciação científica de graduação no perfil profissional dos médicos recém -formados" ] ] "contieneResumen" => array:2 [ "en" => true "pt" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Raphael Joaquim Teles Cyrillo, Sérgio Setúbal, Cyro Teixeira da Silva Júnior, Luis Guillermo Coca Velarde, Ana Carolina Musser Tavares de Mattos, Renato Bergallo Bezerra Cardoso, Gilberto Perez Cardoso" "autores" => array:7 [ 0 => array:2 [ "nombre" => "Raphael Joaquim" "apellidos" => "Teles Cyrillo" ] 1 => array:2 [ "nombre" => "Sérgio" "apellidos" => "Setúbal" ] 2 => array:2 [ "nombre" => "Cyro Teixeira" "apellidos" => "da Silva Júnior" ] 3 => array:2 [ "nombre" => "Luis Guillermo" "apellidos" => "Coca Velarde" ] 4 => array:2 [ "nombre" => "Ana Carolina Musser" "apellidos" => "Tavares de Mattos" ] 5 => array:2 [ "nombre" => "Renato Bergallo" "apellidos" => "Bezerra Cardoso" ] 6 => array:2 [ "nombre" => "Gilberto Perez" "apellidos" => "Cardoso" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511510700786?idApp=UINPBA00004E" "url" => "/21735115/0000001600000005/v1_201305151534/S2173511510700786/v1_201305151534/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2173511510700762" "issn" => "21735115" "doi" => "10.1016/S2173-5115(10)70076-2" "estado" => "S300" "fechaPublicacion" => "2010-09-01" "aid" => "70076" "copyright" => "Sociedade Portuguesa de Pneumologia" "documento" => "article" "crossmark" => 0 "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "fla" "cita" => "Rev Port Pneumol. 2010;16:759-77" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3920 "formatos" => array:3 [ "EPUB" => 242 "HTML" => 2515 "PDF" => 1163 ] ] "en" => array:10 [ "idiomaDefecto" => true "titulo" => "Risk factors for readmission after hospital discharge in chronic obstructive pulmonary disease. The role of quality of life indicators" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "pt" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "759" "paginaFinal" => "777" ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Risco de reinternamento na doença pulmonar obstrutiva crónica – Estudo prospectivo com ênfase no valor da avaliação da qualidade de vida e depressão" ] ] "contieneResumen" => array:2 [ "en" => true "pt" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Rui Carneiro, Cristiana Sousa, Alexandre Pinto, Fernanda Almeida, Júlio R. Oliveira, Nelson Rocha" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Rui" "apellidos" => "Carneiro" ] 1 => array:2 [ "nombre" => "Cristiana" "apellidos" => "Sousa" ] 2 => array:2 [ "nombre" => "Alexandre" "apellidos" => "Pinto" ] 3 => array:2 [ "nombre" => "Fernanda" "apellidos" => "Almeida" ] 4 => array:2 [ "nombre" => "Júlio R." "apellidos" => "Oliveira" ] 5 => array:2 [ "nombre" => "Nelson" "apellidos" => "Rocha" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511510700762?idApp=UINPBA00004E" "url" => "/21735115/0000001600000005/v1_201305151534/S2173511510700762/v1_201305151534/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "titulo" => "Early nasal continuous positive airway pressure versus INSURE in VLBW neonates" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "779" "paginaFinal" => "795" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Ana Saianda, Ricardo M. Fernandes, Joana Saldanha" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Ana" "apellidos" => "Saianda" "email" => array:1 [ 0 => "asaianda@gmail.pt" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Ricardo M." "apellidos" => "Fernandes" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "Joana" "apellidos" => "Saldanha" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Interno do Complementar. Departamento da Criança e da Família. Hospital de Santa Maria – Lisboa/Resident. Child and Family Health Service. Hospital de Santa Maria – Lisboa, Neonatal Unit. Hospital de Santa Maria – Lisboa" "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Assistente graduada. Departamento da Criança e da Família. Unidade de Neonatologia. Hospital de Santa Maria – Lisboa/Consultant. Child and Family Health Service., Neonatal Unit. Hospital de Santa Maria – Lisboa" "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondence to/Correspondência: Departamento de Pediatria. Hospital de Santa Maria, Av. Professor. Egas Moniz, 1649-035 Lisboa." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Uso do método INSURE <span class="elsevierStyleItalic">versus</span> CPAP nasal isolado em recém-nascidos de muito baixo peso com 30 ou menos semanas de gestação" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-10-19" "fechaAceptado" => "2010-07-05" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key-words" "identificador" => "xpalclavsec161034" "palabras" => array:6 [ 0 => "Very low birth weight" 1 => "nCPAP ventilation" 2 => "INSURE" 3 => "respiratory distress syndrome (newborn)" 4 => "chronic lung disease of prematurity" 5 => "mortality" ] ] ] "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec161035" "palabras" => array:6 [ 0 => "Recém-nascido muito baixo peso" 1 => "nCPAP" 2 => "INSURE" 3 => "sindroma de dificuldade respiratória neonatal" 4 => "doença pulmonar crónica da prematuridade" 5 => "mortalidade" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Evidence suggests the INSURE strategy (INtubate-SURfactant administration and Extubate to nasal continuous positive airway pressure [nCPAP]) is superior to mechanical ventilation (MV) with rescue surfactant for the management of respiratory distress syndrome (RDS) in very low birth weight (VLBW) neonates. There is limited data, however, to assess whether INSURE is superior to nCPAP alone. We aimed to compare these two strategies regarding early and late outcomes.</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Retrospective cohort study from Jan/2002 to Aug/2008. We included VLBW neonateswith gestational age (GA) ≤ 30 weeks registered in the Vermont Oxford Network that used either nCPAP alone (nCPAP group, N<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>40), or with INSURE (INSURE group, N<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>56). We assessed early (RDS, need for rescue surfactant, and CPAP failure with MV) and late outcomes (chronic lung disease of prematurity (CLD), mortality, and composite outcome of mortality and/or CLD).</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Neonates in the INSURE group had lower mean GA, while other baseline variables were comparable. The proportion of RDS was significantly superior in the nCPAP group (53% vs. 30%; adjusted OR [95% CI] – 0.2 [0.1-0.6]). Therapeutic surfactant was administered to all cases with RDS in the nCPAP group, but to none from the INSURE group. MV was more frequently required in the nCPAP group (11/ 40, 28% <span class="elsevierStyleItalic">vs</span>. 9/ 56, 12%; p<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>0.04). No statistically significant differences were found in either of the late outcomes.</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The use of nCPAP alone in VLBW neonates with GA ≤ 30 weeks may be associated with slightly poorer early outcomes than the INSURE strategy, but there were no significant differences in CLD or mortality.</p>" ] "pt" => array:2 [ "titulo" => "Resumo" "resumen" => "<span class="elsevierStyleSectionTitle">Introdução</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Pretende-se determinar se a utilização do método INSURE em recém-nascidos de muito baixo peso, com idade gestacional (IG) ≤ 30 semanas se associa a menor morbilidade e mortalidade quando comparado com uso de nCPAP isolado.</p> <span class="elsevierStyleSectionTitle">Métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Estudo de coorte retrospectiva dos RNMBP nascidos num hospital de apoio perinatal diferenciado entre Janeiro/2002-Agosto/2008. Incluíram-se as crianças registadas na Vermont-Oxford Network com IG ≤30semanas e com uso de nCPAP logo após o nascimento (N<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>96). Estabeleceu-se Grupo nCPAP – uso de nCPAP isolado (N<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>40) e Grupo INSURE (N<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>56). Consideraram-se <span class="elsevierStyleItalic">outcomes</span> precoces: síndroma de dificuldade respiratória (SDR), necessidade de administrar surfactante com intuito terapêutico ou recurso a ventilação invasiva. Compararam-se igualmente <span class="elsevierStyleItalic">outcomes</span> tardios: doença pulmonar crónica da prematuridade (DPC), mortalidade e o <span class="elsevierStyleItalic">outcome</span> composto DPC-mortalidade.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">No grupo INSURE verificou-se menor IG, não se registando diferenças relativamente ao peso ao nascer e indução da maturação pulmonar. Verificou-se SDR em 21/40 (53%) casos do grupo nCPAP e em 17/56 (30%) casos do grupo INSURE (OR ajustado [IC 95%] – 0,2 [0,1-0,6]). No grupo nCPAP todos estes casos realizaram surfactante com intuito terapêutico, não tendo sido efectuada nenhuma dose adicional de surfactante no grupo INSURE. Verificou-se maior número de casos com necessidade de VI no grupo nCPAP do que no grupo INSURE (11/40, 28% <span class="elsevierStyleItalic">vs</span> 9/56, 12%). Não foram encontradas diferenças estatisticamente significativas relativamente aos <span class="elsevierStyleItalic">outcomes</span> tardios.</p> <span class="elsevierStyleSectionTitle">Conclusão</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Em RNMBP com IG ≤30sem, o uso isolado de nCPAP poderá traduzir-se numa ligeira desvantagem em <span class="elsevierStyleItalic">outcomes</span> precoces, sem evidentes repercussões em termos de DPC ou mortalidade.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliography/Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:16 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neonatal care of very-low-birthweight infants in special-care units and neonatal intensive-care units in Stockholm. Early nasal continuous positive airway pressure versus mechanical ventilation: gain and losses" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "B. Jónsson" 1 => "M. Katz-Salamon" 2 => "G. Faxelius" 3 => "U. Broberger" 4 => "H. Lagercrantz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Paediatr Suppl" "fecha" => "1997" "volumen" => "419" "paginaInicial" => "4" "paginaFinal" => "10" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9185897" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Variables associated with the early failure of nasal CPAP in very low birth weigth infants" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:5 [ 0 => "A. Ammari" 1 => "M. Suri" 2 => "V. Milisavljevic" 3 => "R. Sahni" 4 => "D. Bateman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jpeds.2005.04.062" "Revista" => array:6 [ "tituloSerie" => "J Pediatr" "fecha" => "2005" "volumen" => "147" "paginaInicial" => "341" "paginaFinal" => "347" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16182673" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Is it safer to intubate Premature Infants in the delivery room?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "H. Aly" 1 => "A.N. Massaro" 2 => "K. Patel" 3 => "A. El-Mohandes" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1542/peds.2004-2493" "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "2005" "volumen" => "115" "paginaInicial" => "1660" "paginaFinal" => "1665" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15930230" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "European consensus guidelines on the management of neonatal respiratory distress syndrome" "autores" => array:1 [ 0 => array:3 [ "colaboracion" => "Working Group on Prematurity of the World Association of Perinatal Medicine" "etal" => true "autores" => array:5 [ 0 => "D. Sweet" 1 => "G. Bevilacqua" 2 => "V. Carnielli" 3 => "G. Greisen" 4 => "R. Plavka" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1515/JPM.2007.048" "Revista" => array:7 [ "tituloSerie" => "J Perinat Med" "fecha" => "2007" "volumen" => "35" "numero" => "3" "paginaInicial" => "175" "paginaFinal" => "186" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17480144" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Early surfactant administration with brief ventilation vs. selective surfactant and continued mechanical ventilation for preterm infants with or at risk for respiratory distress syndrome" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "T.P. Stevens" 1 => "E.W. Harrington" 2 => "M. Blennow" 3 => "R.F. Soll" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Cochrane Database Syst Rev" "fecha" => "2007" "volumen" => "17" "numero" => "4" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Continuous positive airway pressure and surfactant; Combined data from animal experiments and clinical trials" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M.A. Thomson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "56766" "Revista" => array:6 [ "tituloSerie" => "Biol Neonate" "fecha" => "2002" "volumen" => "81" "paginaInicial" => "16" "paginaFinal" => "19" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12011561" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "CPAP and the preterm infant. Lessons from COIN trial and other studies" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "Hascoet. Jean-Michel" 1 => "Espange. Sandrine" 2 => "Hamon. Isabelle" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.earlhumdev.2008.09.003" "Revista" => array:6 [ "tituloSerie" => "Early Hum Dev" "fecha" => "2008" "volumen" => "84" "paginaInicial" => "791" "paginaFinal" => "793" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18804926" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:1 [ "host" => array:1 [ 0 => array:1 [ "WWW" => array:1 [ "link" => "www.vtoxford.org" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nasal CPAP or intubation at birth for very preterm infants" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:5 [ 0 => "C.J. Morley" 1 => "P.G. Davis" 2 => "L.W. Doyle" 3 => "L.P. Brion" 4 => "J.M. Hascoet" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJMoa072788" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2008" "volumen" => "358" "paginaInicial" => "700" "paginaFinal" => "708" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18272893" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surfactant therapy and nasal continuos positive airway pressure for newborns with respiratory distress syndrome" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:5 [ 0 => "H. Verder" 1 => "B. Robertson" 2 => "G. Greisen" 3 => "F. Ebbesen" 4 => "P. Albertsen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199410203311603" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1994" "volumen" => "331" "paginaInicial" => "1051" "paginaFinal" => "1055" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8090164" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nasal continuos positive airway pressure and early surfactant therapy for respiratory distress syndrome in newborns of less than 30 weeks’ gestation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:5 [ 0 => "H. Verder" 1 => "P. Albertsen" 2 => "F. Ebbesen" 3 => "G. Greisen" 4 => "B. Robertson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Pediatrics" "fecha" => "1999" "volumen" => "103" "numero" => "2" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10049991" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Timing of initial surfactant treatment for infants 23 to 29 weeks’ gestation; is routine practice evidence based?" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:5 [ 0 => "J. Horbar" 1 => "J.H. Carpenter" 2 => "J. Buzas" 3 => "R.F. Soll" 4 => "G. Suresh" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "2004" "volumen" => "113" "paginaInicial" => "1593" "paginaFinal" => "1602" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15173479" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Implementation of surfactant treatment during continuous positive airway pressure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "K. Bohlin" 1 => "T. Gudmundsdottir" 2 => "M. Katz-Salamon" 3 => "B. Jonsson" 4 => "M. Blennow" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/sj.jp.7211754" "Revista" => array:7 [ "tituloSerie" => "J Perinatol" "fecha" => "2007" "volumen" => "27" "numero" => "7" "paginaInicial" => "422" "paginaFinal" => "427" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17476269" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Very early surfactant without mandatory ventilation in premature infants treated with early continuous positive airway pressure: a randomized, controlled trial" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:5 [ 0 => "M.A. Rojas" 1 => "J.M. Lozano" 2 => "M.X. Rojas" 3 => "M. Laughon" 4 => "C.L. Bose" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1542/peds.2007-3501" "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "2009" "volumen" => "123" "paginaInicial" => "137" "paginaFinal" => "142" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19117872" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "and the Committee on Fetus and Newborn. Surfactant-replacement therapy for respiratory distress in the preterm and term neonate" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "W. Engle" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1542/peds.2007-3283" "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "2008" "volumen" => "121" "paginaInicial" => "419" "paginaFinal" => "432" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18245434" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Martins V, Consenso Nacional da Sociedade Portuguesa de Neonatologia – nCPAP. Apresentado no “V seminario – Ventilacao no recem-nascido – dos aspectos basicos a aplicacao pratica”. Braga, 15-16 Maio 2009." ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735115/0000001600000005/v1_201305151534/S2173511510700774/v1_201305151534/en/main.assets" "Apartado" => array:4 [ "identificador" => "9552" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Original Article/Artigo Original" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001600000005/v1_201305151534/S2173511510700774/v1_201305151534/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511510700774?idApp=UINPBA00004E" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 6 | 4 | 10 |
2024 October | 24 | 32 | 56 |
2024 September | 22 | 25 | 47 |
2024 August | 40 | 38 | 78 |
2024 July | 25 | 33 | 58 |
2024 June | 19 | 24 | 43 |
2024 May | 30 | 26 | 56 |
2024 April | 16 | 26 | 42 |
2024 March | 20 | 25 | 45 |
2024 February | 20 | 21 | 41 |
2024 January | 12 | 30 | 42 |
2023 December | 13 | 22 | 35 |
2023 November | 15 | 24 | 39 |
2023 October | 9 | 33 | 42 |
2023 September | 17 | 34 | 51 |
2023 August | 9 | 14 | 23 |
2023 July | 12 | 22 | 34 |
2023 June | 17 | 13 | 30 |
2023 May | 20 | 25 | 45 |
2023 April | 9 | 13 | 22 |