array:24 [
  "pii" => "S2173511512000759"
  "issn" => "21735115"
  "doi" => "10.1016/j.rppnen.2012.08.002"
  "estado" => "S300"
  "fechaPublicacion" => "2012-09-01"
  "aid" => "98"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2012"
  "documento" => "simple-article"
  "crossmark" => 0
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "edi"
  "cita" => "Rev Port Pneumol. 2012;18:214-6"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 5850
    "formatos" => array:3 [
      "EPUB" => 221
      "HTML" => 4393
      "PDF" => 1236
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S2173511512000280"
    "issn" => "21735115"
    "doi" => "10.1016/j.rppnen.2012.04.001"
    "estado" => "S300"
    "fechaPublicacion" => "2012-09-01"
    "aid" => "89"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Pneumol. 2012;18:217-25"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4641
      "formatos" => array:3 [
        "EPUB" => 250
        "HTML" => 3219
        "PDF" => 1172
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
      "titulo" => "Evolution of functional capacity and health status 2 years after a Pulmonary Rehabilitation Program"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "217"
          "paginaFinal" => "225"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Evolu&#231;&#227;o da capacidade funcional e estado de sa&#250;de 2 anos ap&#243;s um programa de reabilita&#231;&#227;o respirat&#243;ria"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 1090
              "Ancho" => 1729
              "Tamanyo" => 95784
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Results for St&#46; George&#39;s Respiratory Questionnaire &#40;SGRQ&#41;&#46; Data are represented as mean value<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>SD&#46;</p> <p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">PRP&#58; Pulmonary Rehabilitation Program&#59; Pre&#58; before pulmonary rehabilitation&#46; &#42;Significant improvement after rehabilitation &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05&#41;&#46; Difference &#40;in m&#41; After &#8211; pre-PRP appears in brackets&#46;</p> <p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Sample sizes&#58; 24&#44; 24&#44; 14&#44; 17 for pre-PRP&#44; after PRP&#44; 1 year and 2 years&#44; respectively&#44; for the active group&#59; 8&#44; 8&#44; 2&#44; 3 for pre-PRP&#44; after PRP&#44; 1 year and 2 years&#44; respectively&#44; for the control group&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "V&#46; Areias, D&#46; Ferreira, A&#46; Martins, I&#46; Matias, F&#46; Negrinho, F&#46; Rodrigues"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "V&#46;"
              "apellidos" => "Areias"
            ]
            1 => array:2 [
              "nombre" => "D&#46;"
              "apellidos" => "Ferreira"
            ]
            2 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Martins"
            ]
            3 => array:2 [
              "nombre" => "I&#46;"
              "apellidos" => "Matias"
            ]
            4 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Negrinho"
            ]
            5 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Rodrigues"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "pt" => array:9 [
        "pii" => "S087321591200030X"
        "doi" => "10.1016/j.rppneu.2012.02.010"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "pt"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S087321591200030X?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511512000280?idApp=UINPBA00004E"
    "url" => "/21735115/0000001800000005/v1_201305151607/S2173511512000280/v1_201305151607/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173511512000747"
    "issn" => "21735115"
    "doi" => "10.1016/j.rppnen.2012.08.001"
    "estado" => "S300"
    "fechaPublicacion" => "2012-09-01"
    "aid" => "103"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "edi"
    "cita" => "Rev Port Pneumol. 2012;18:211-3"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3733
      "formatos" => array:3 [
        "EPUB" => 224
        "HTML" => 2576
        "PDF" => 933
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">New perspectives in pulmonology</span>"
      "titulo" => "Prolonged mechanical ventilation&#58; New facilities and new models of care"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "211"
          "paginaFinal" => "213"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Ventila&#231;&#227;o mec&#226;nica prolongada&#58; novas instala&#231;&#245;es e novos modelos de atendimento"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "N&#46; Ambrosino"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "N&#46;"
              "apellidos" => "Ambrosino"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511512000747?idApp=UINPBA00004E"
    "url" => "/21735115/0000001800000005/v1_201305151607/S2173511512000747/v1_201305151607/en/main.assets"
  ]
  "en" => array:12 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">New perspectives in pulmonology</span>"
    "titulo" => "Long-term ventilator-dependent patients&#58; New facilities and new models of care&#46; The American perspective"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "214"
        "paginaFinal" => "216"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "G&#46; Criner"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "G&#46;"
            "apellidos" => "Criner"
            "email" => array:1 [
              0 => "crinerg&#64;tuhs&#46;temple&#46;edu"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Temple University School of Medicine&#44; Philadelphia&#44; United States"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Pacientes dependentes de ventilador a longo prazo&#58; novas instala&#231;&#245;es e novos modelos de atendimento&#46; A perspectiva Americana"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The number of patients who receive mechanical ventilation as life support is rapidly increasing due to improvements in life saving medical therapy in critically ill patients&#44; an aging population and the expanded use of aggressive surgical procedures&#46; The historic annualized increase in prolonged mechanical ventilation use in the U&#46;S&#46; is approximately 5&#46;5&#37; compared with a 1&#37; per annum increase in U&#46;S&#46; hospital admissions&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> It is estimated that the population of patients who receive prolonged mechanical ventilation in the U&#46;S&#46; will more than double by the year 2020 and reach approximately 605&#44;898 cases&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> The increased number of patients who require prolonged mechanical ventilation strains the available resources of intensive care units &#40;ICU&#41; by requiring a greater degree of medical care and ICU hospitalization that exceeds the median length of stay&#46; Mechanical ventilation is expensive therapy&#59; patients who receive ventilation in the ICU disproportionately contribute to the high cost of ICU care&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Dasta and colleagues reported that ICU patients who require mechanical ventilation compared to ICU patients who do not receive mechanical ventilation have 50&#37; higher costs and treatment with mechanical ventilation accounts for 51&#37; of their total hospital costs&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Those who require prolonged ventilation consume an even greater percentage of heath care dollars&#46; In an analysis of over 31 million hospital discharges for adults in 2003&#44; Zilberberg reported a greater median length of stay &#40;17 vs&#46; 6 days&#41; and hospital costs &#40;&#36;40&#44;903 vs&#46; &#36;13&#44;434&#41; for those who received mechanical ventilation &#8805;96<span class="elsevierStyleHsp" style=""></span>h compared to those who received mechanical ventilation &#60;96<span class="elsevierStyleHsp" style=""></span>h&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> Patients who are ventilated for &#8805;21 days have even higher costs&#59; the cost per one-year survival is &#36;423&#44;596&#44; &#36;266&#44;105 and &#36;165&#44;075 for patients ventilated &#8805;21 days&#44; &#8805;96<span class="elsevierStyleHsp" style=""></span>h with a tracheostomy and &#60;96<span class="elsevierStyleHsp" style=""></span>h&#44; respectively&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Carson reported on 126 patients ventilated &#8805;4 days with tracheostomy or &#8805;21 days without tracheostomy who were treated at one health care system and then followed prospectively for one year to determine the trajectories of their care and resource utilization&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> One hundred and three survivors &#40;82&#37;&#41; had 457 separate transitions in post discharge care location &#40;median 4 transitions&#44; including 68 patients who were readmitted at least once&#41;&#46; Patients spent an average of 74&#37; of all days either in a hospital or post acute care setting or received home health care&#46; At one year&#44; 11 patients &#40;9&#37;&#41; had a good outcome &#8211; alive without functional dependency&#44; 33 &#40;24&#37;&#41; had a moderate outcome &#8211; alive with moderate dependency and 82 &#40;65&#37;&#41; had a poor outcome&#44; either alive with complete functional dependency &#40;4 patients&#44; 21&#37;&#41; or dead &#40;56 patients&#44; 44&#37;&#41;&#46; Those with poor outcomes were older&#44; had more comorbid conditions and were more frequently discharged to a post acute care facility&#46; The mean cost per patient was &#36;306&#44;135 and for the total cohort &#36;38 million were spent for their medical care for an estimated &#36;3&#46;5 million per one independently functioning survivor at one year&#46; These data suggest that some patients who receive prolonged ventilation consume considerable resources in their last year of life with low likelihood of any meaningful quality of life&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Some reports of patients who receive prolonged ventilation&#44; however&#44; show much better outcomes&#44; both in terms of survival and quality of life&#46; Gracey and colleagues reported a 65&#37; survival at one year in patients treated in a multidisciplinary care unit&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> Chatila showed an acceptable quality of life in patients receiving prolonged ventilation of &#62;21 consecutive days with tracheostomy&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> Mamary et al&#46; recently reported in 182 consecutive patients receiving prolonged ventilation for &#62;55<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>42 days a 75&#37; one-year and 59&#37; three-year survival&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> All of these studies were conducted in special Chronic Ventilator Dependent Demonstration Units of the Health Care Financing Administration &#40;HCFA&#41; that were geared to provide long-term ventilation outside of the ICU to selected patients expected to have high likelihood of benefitting from multidisciplinary treatment plans focused on restoring functional capacity via whole body rehabilitation&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Besides the growing numbers of patients that require prolonged mechanical ventilation&#44; geographic constraints on ICU bed capacity and the high cost of care&#44; many other issues have been identified that adversely affect the plight of patients who require prolonged ventilation&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> These include&#58; the high mortality reported in patients receiving prolonged mechanical ventilation&#44; the substantial number and severity of associated comorbidities &#40;impaired cognition&#44; decreased functional status&#44; impaired swallowing&#41;&#44; the quality of life following prolonged ventilation&#44; the cost-effectiveness of care&#44; the optimal treatment plan and the best location of care&#46; Even more basic&#44; the definition of what constitutes prolonged mechanical ventilation is still a matter of debate&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The definition of prolonged ventilation has ranged from &#8805;48 consecutive hours to &#8805;96 consecutive hours with tracheostomy to &#8805;21 consecutive days with at least 6<span class="elsevierStyleHsp" style=""></span>h of ventilation daily&#46; The HCFA Chronic Ventilator Dependent Unit Demonstration Project that was conducted in the 1990s used the later definition&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> The Chronic Ventilator Dependent Unit Demonstration Project purposely selected a patient cohort who was chronically ventilated but medically stable enough not to require ongoing aggressive non-pulmonary ICU care but continued to require mechanical ventilation and needed rehabilitation to restore their functional status&#46; Patients who require mechanical ventilation for longer durations are usually older&#44; sicker&#59; receive mechanical ventilation longer before weaning attempts are begun and are more likely to have underlying COPD or pneumonia as the cause of respiratory failure&#46; Moreover&#44; they tend to have higher mortality and although fewer in number they incur longer lengths of stay and have much higher associated costs of care&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">The location of care for patients receiving prolonged ventilation in the U&#46;S&#46; migrated out of the acute care hospital in the mid 1990s due to adoption of the Prospective Payment System Designated Related Group &#40;DRG&#41; reimbursement scheme to specialized weaning centers&#44; long-term acute care hospitals or skilled nursing facilities that accept ventilated patients&#46; The Prospective Payment System utilized in the U&#46;S&#46; assigns payment scales to the care of patients who require mechanical ventilation with a tracheotomy operation performed except face&#44; neck and mouth diagnosis &#40;DRG 541&#44; &#36;89&#44; 000&#41; and mechanical ventilation &#8805;96<span class="elsevierStyleHsp" style=""></span>h without tracheotomy operation performed except face&#44; neck and mouth diagnosis &#40;DRG 542&#44; &#36;43&#44;000&#41; with the aim of bundling the cost of care and triaging differential payments for patients with higher care demands and resultant costs of care&#46; The reported patient outcomes from these long-term acute care and skilled nursing facilities have been mixed&#59; some reports show high one-year mortality with limited weaning success&#46; Patients receiving mechanical ventilation who are transferred directly from the ICU to a lower acuity facility have been reported to have a high rate of readmission and mortality&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> However&#44; the selection criteria used to admit patients to these facilities and the description and intensity of the rehabilitative and pulmonary treatment plans that are utilized by these alternative locations of care are variable and limited&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Programs that utilize a comprehensive multidisciplinary rehabilitative approach to treat patients receiving prolonged ventilation have uniformly reported better survival and functional outcomes&#46; The components of these programs that are considered essential for success&#44; include strong medical respiratory specialist leadership&#44; a multidisciplinary staff of nurses specialized in the care of ventilated patients&#44; physical and respiratory therapists&#44; speech therapists&#44; psychologists and nutritional support&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">13&#44;14</span></a> In fact several studies have demonstrated that whole body and respiratory muscle training can facilitate an increase in functional performance&#44; limb and respiratory muscle strengthening and liberation from mechanical ventilation&#46;<a class="elsevierStyleCrossRefs" href="#bib0070"><span class="elsevierStyleSup">14&#8211;16</span></a> Martin and colleagues have shown that an increase in upper extremity strength correlates better than any other spontaneous breathing variable in predicting weaning success&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">Because of the specialized needs of the patients receiving prolonged ventilation&#44; it has been suggested that regional centers of excellence may not only be more cost effective&#44; but also result in better outcomes&#46; Lone et al&#46; reviewed a database of admission to 3 UK ICUs and found that the incidence of patients requiring prolonged mechanical ventilation was 4&#46;4 per 100 ICU admissions and 6&#46;3 per ventilated ICU admission&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">17</span></a> PMV patients used 29&#46;15 of all general ICU bed days and spent a longer time in the hospital than non-PMV patients &#40;median 17 vs&#46; 7 days&#41;&#46;They suggested that a three bed weaning unit could result in cost savings and unlock ICU beds for other patients&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">17</span></a> In general&#44; outcomes from mechanical ventilation have been reported to be better when conducted at high volume rather than low volume centers&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">18</span></a> A cogent argument could be made that patients who receive prolonged ventilation need the most specialized care plan and their outcomes might be best served in regionalized centers of excellence that are dedicated to the evaluation and treatment of this patient group&#46; That conclusion was also reached after analysis of the HCFA Chronic ventilator demonstration project&#44; but limitations in funding prohibited their establishment&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Patients who require prolonged mechanical ventilation place unique demands on the health care delivery system that impacts not only those who receive that therapy but other patients who receive care in the intensive care unit or compete for medical resources in a medical care delivery system currently under duress&#46; Appropriate selection of patients receiving prolonged ventilation that may benefit from continued aggressive medical care&#44; whole body rehabilitation and continued weaning efforts is required&#44; however&#44; the complete characterization of those patients most likely to benefit still awaits identification&#46;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">19</span></a> Future research is needed to identify those patients receiving prolonged mechanical ventilation who are most likely to benefit from comprehensive and aggressive medical care from those who are dying a protracted death to optimize patient outcome and alleviate unnecessary suffering&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Conflicts of interest</span><p id="par0045" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflicts of interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:19 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Growth in adult prolonged acute mechanical ventilation&#58; implications for healthcare delivery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;D&#46; Zilberberg"
                            1 => "M&#46; de Wit"
                            2 => "J&#46;R&#46; Pirone"
                            3 => "A&#46;F&#46; Shorr"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CCM.0b013e3181691a49"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2008"
                        "volumen" => "36"
                        "paginaInicial" => "1451"
                        "paginaFinal" => "1455"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18434911"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term ventilation introduction and perspectives"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "G&#46;J&#46; Criner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Respir Care Clin N Am"
                        "fecha" => "2002"
                        "volumen" => "8"
                        "paginaInicial" => "345"
                        "paginaFinal" => "353"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12481961"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Daily cost of an intensive care unit day&#58; the contribution of mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;F&#46; Dasta"
                            1 => "T&#46;P&#46; McLaughlin"
                            2 => "S&#46;H&#46; Mody"
                            3 => "C&#46;T&#46; Piech"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2005"
                        "volumen" => "33"
                        "paginaInicial" => "1266"
                        "paginaFinal" => "1271"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15942342"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prolonged acute mechanical ventilation&#44; hospital resource utilization&#44; and mortality in the United States"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;D&#46; Zilberberg"
                            1 => "R&#46;S&#46; Luippold"
                            2 => "S&#46; Sulsky"
                            3 => "A&#46;F&#46; Shorr"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CCM.0B013E31816536F7"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2008"
                        "volumen" => "36"
                        "paginaInicial" => "724"
                        "paginaFinal" => "730"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18209667"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An economic evaluation of prolonged mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46;E&#46; Cox"
                            1 => "S&#46;S&#46; Carson"
                            2 => "J&#46;A&#46; Govert"
                            3 => "L&#46; Chelluri"
                            4 => "G&#46;D&#46; Sanders"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.CCM.0000275391.35834.10"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2007"
                        "volumen" => "35"
                        "paginaInicial" => "1918"
                        "paginaFinal" => "1927"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17581479"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A prognostic model for one-year mortality in patients requiring prolonged mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46;S&#46; Carson"
                            1 => "J&#46; Garrett"
                            2 => "L&#46;C&#46; Hanson"
                            3 => "J&#46; Lanier"
                            4 => "J&#46; Govert"
                            5 => "M&#46;C&#46; Brake"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CCM.0b013e31817b8925"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2008"
                        "volumen" => "36"
                        "paginaInicial" => "2061"
                        "paginaFinal" => "2069"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18552692"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The chronic ventilator-dependent unit&#58; a lower-cost alternative to intensive care"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46;R&#46; Gracey"
                            1 => "D&#46;C&#46; Hardy"
                            2 => "G&#46;E&#46; Koenig"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4065/75.5.445"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mayo Clin Proc"
                        "fecha" => "2000"
                        "volumen" => "75"
                        "paginaInicial" => "445"
                        "paginaFinal" => "449"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10807071"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Quality of life in survivors of prolonged mechanical ventilatory support"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "W&#46; Chatila"
                            1 => "D&#46;T&#46; Kreimer"
                            2 => "G&#46;J&#46; Criner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2001"
                        "volumen" => "29"
                        "paginaInicial" => "737"
                        "paginaFinal" => "742"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11373458"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Survival in patients receiving prolonged ventilation&#58; factors that influence outcome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46;J&#46; Mamary"
                            1 => "S&#46; Kondapaneni"
                            2 => "G&#46;B&#46; Vance"
                            3 => "J&#46;P&#46; Gaughan"
                            4 => "U&#46;J&#46; Martin"
                            5 => "G&#46;J&#46; Criner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4137/CCRPM.S6649"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Med Insights Circ Respir Pulm Med"
                        "fecha" => "2011"
                        "volumen" => "5"
                        "paginaInicial" => "17"
                        "paginaFinal" => "26"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21573034"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Care of the patient requiring invasive mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "G&#46;J&#46; Criner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Respir Care Clin N Am"
                        "fecha" => "2002"
                        "volumen" => "8"
                        "paginaInicial" => "575"
                        "paginaFinal" => "592"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12602416"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characteristics and outcomes of ventilated patients according to time to liberation from mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "O&#46; Penuelas"
                            1 => "F&#46; Frutos-Vivar"
                            2 => "C&#46; Fernandez"
                            3 => "A&#46; Anzueto"
                            4 => "S&#46;K&#46; Epstein"
                            5 => "C&#46; Apezteguia"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.162.2.9905058"
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2011"
                        "paginaInicial" => "430"
                        "paginaFinal" => "437"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10934065"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Survivors of catastrophic illness&#58; outcome after direct transfer from intensive care to extended care facilities"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46;A&#46; Nasraway"
                            1 => "G&#46;J&#46; Button"
                            2 => "W&#46;M&#46; Rand"
                            3 => "T&#46; Hudson-Jinks"
                            4 => "M&#46; Gustafson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2000"
                        "volumen" => "28"
                        "paginaInicial" => "19"
                        "paginaFinal" => "25"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10667494"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Overview of improving tolerance of long-term mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46;J&#46; Criner"
                            1 => "A&#46; Tzouanakis"
                            2 => "D&#46;T&#46; Kreimer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Clin"
                        "fecha" => "1994"
                        "volumen" => "10"
                        "paginaInicial" => "845"
                        "paginaFinal" => "866"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8000930"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Impact of whole-body rehabilitation in patients receiving chronic mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "U&#46;J&#46; Martin"
                            1 => "L&#46; Hincapie"
                            2 => "M&#46; Nimchuk"
                            3 => "J&#46; Gaughan"
                            4 => "G&#46;J&#46; Criner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2005"
                        "volumen" => "33"
                        "paginaInicial" => "2259"
                        "paginaFinal" => "2265"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16215380"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use of inspiratory muscle strength training to facilitate ventilator weaning&#58; a series of 10 consecutive patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46;D&#46; Martin"
                            1 => "P&#46;D&#46; Davenport"
                            2 => "A&#46;C&#46; Franceschi"
                            3 => "E&#46; Harman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2002"
                        "volumen" => "122"
                        "paginaInicial" => "192"
                        "paginaFinal" => "196"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12114357"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effects of physical training on functional status in patients with prolonged mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "L&#46;L&#46; Chiang"
                            1 => "L&#46;Y&#46; Wang"
                            2 => "C&#46;P&#46; Wu"
                            3 => "H&#46;D&#46; Wu"
                            4 => "Y&#46;T&#46; Wu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2522/ptj.20050036"
                      "Revista" => array:6 [
                        "tituloSerie" => "Phys Ther"
                        "fecha" => "2006"
                        "volumen" => "86"
                        "paginaInicial" => "1271"
                        "paginaFinal" => "1281"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16959675"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prolonged mechanical ventilation in critically ill patients&#58; epidemiology&#44; outcomes and modeling the potential cost consequences of establishing a regional weaning unit"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "N&#46;I&#46; Lone"
                            1 => "T&#46;S&#46; Walsh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/cc10117"
                      "Revista" => array:5 [
                        "tituloSerie" => "Crit Care"
                        "fecha" => "2011"
                        "volumen" => "15"
                        "paginaInicial" => "R102"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21439086"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Potential value of regionalized intensive care for mechanically ventilated medical patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;M&#46; Kahn"
                            1 => "W&#46;T&#46; Linde-Zwirble"
                            2 => "H&#46; Wunsch"
                            3 => "A&#46;E&#46; Barnato"
                            4 => "T&#46;J&#46; Iwashyna"
                            5 => "M&#46;S&#46; Roberts"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/rccm.200708-1214OC"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2008"
                        "volumen" => "177"
                        "paginaInicial" => "285"
                        "paginaFinal" => "291"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18006884"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Management of patients requiring prolonged mechanical ventilation&#58; report of a NAMDRC consensus conference"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "N&#46;R&#46; MacIntyre"
                            1 => "S&#46;K&#46; Epstein"
                            2 => "S&#46; Carson"
                            3 => "D&#46; Scheinhorn"
                            4 => "K&#46; Christopher"
                            5 => "S&#46; Muldoon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.128.6.3937"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2005"
                        "volumen" => "128"
                        "paginaInicial" => "3937"
                        "paginaFinal" => "3954"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16354866"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735115/0000001800000005/v1_201305151607/S2173511512000759/v1_201305151607/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9738"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "New perspectives in Pulmonology"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001800000005/v1_201305151607/S2173511512000759/v1_201305151607/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511512000759?idApp=UINPBA00004E"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

New perspectives in pulmonology
Long-term ventilator-dependent patients: New facilities and new models of care. The American perspective
Pacientes dependentes de ventilador a longo prazo: novas instalações e novos modelos de atendimento. A perspectiva Americana
G. Criner
Temple University School of Medicine, Philadelphia, United States
Read
935
Times
was read the article
505
Total PDF
430
Total HTML
Share statistics
 array:24 [
  "pii" => "S2173511512000759"
  "issn" => "21735115"
  "doi" => "10.1016/j.rppnen.2012.08.002"
  "estado" => "S300"
  "fechaPublicacion" => "2012-09-01"
  "aid" => "98"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2012"
  "documento" => "simple-article"
  "crossmark" => 0
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "edi"
  "cita" => "Rev Port Pneumol. 2012;18:214-6"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 5850
    "formatos" => array:3 [
      "EPUB" => 221
      "HTML" => 4393
      "PDF" => 1236
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S2173511512000280"
    "issn" => "21735115"
    "doi" => "10.1016/j.rppnen.2012.04.001"
    "estado" => "S300"
    "fechaPublicacion" => "2012-09-01"
    "aid" => "89"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Pneumol. 2012;18:217-25"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4641
      "formatos" => array:3 [
        "EPUB" => 250
        "HTML" => 3219
        "PDF" => 1172
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
      "titulo" => "Evolution of functional capacity and health status 2 years after a Pulmonary Rehabilitation Program"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "217"
          "paginaFinal" => "225"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Evolu&#231;&#227;o da capacidade funcional e estado de sa&#250;de 2 anos ap&#243;s um programa de reabilita&#231;&#227;o respirat&#243;ria"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 1090
              "Ancho" => 1729
              "Tamanyo" => 95784
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Results for St&#46; George&#39;s Respiratory Questionnaire &#40;SGRQ&#41;&#46; Data are represented as mean value<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>SD&#46;</p> <p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">PRP&#58; Pulmonary Rehabilitation Program&#59; Pre&#58; before pulmonary rehabilitation&#46; &#42;Significant improvement after rehabilitation &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05&#41;&#46; Difference &#40;in m&#41; After &#8211; pre-PRP appears in brackets&#46;</p> <p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Sample sizes&#58; 24&#44; 24&#44; 14&#44; 17 for pre-PRP&#44; after PRP&#44; 1 year and 2 years&#44; respectively&#44; for the active group&#59; 8&#44; 8&#44; 2&#44; 3 for pre-PRP&#44; after PRP&#44; 1 year and 2 years&#44; respectively&#44; for the control group&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "V&#46; Areias, D&#46; Ferreira, A&#46; Martins, I&#46; Matias, F&#46; Negrinho, F&#46; Rodrigues"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "V&#46;"
              "apellidos" => "Areias"
            ]
            1 => array:2 [
              "nombre" => "D&#46;"
              "apellidos" => "Ferreira"
            ]
            2 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Martins"
            ]
            3 => array:2 [
              "nombre" => "I&#46;"
              "apellidos" => "Matias"
            ]
            4 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Negrinho"
            ]
            5 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Rodrigues"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "pt" => array:9 [
        "pii" => "S087321591200030X"
        "doi" => "10.1016/j.rppneu.2012.02.010"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "pt"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S087321591200030X?idApp=UINPBA00004E"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511512000280?idApp=UINPBA00004E"
    "url" => "/21735115/0000001800000005/v1_201305151607/S2173511512000280/v1_201305151607/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173511512000747"
    "issn" => "21735115"
    "doi" => "10.1016/j.rppnen.2012.08.001"
    "estado" => "S300"
    "fechaPublicacion" => "2012-09-01"
    "aid" => "103"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "edi"
    "cita" => "Rev Port Pneumol. 2012;18:211-3"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3733
      "formatos" => array:3 [
        "EPUB" => 224
        "HTML" => 2576
        "PDF" => 933
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">New perspectives in pulmonology</span>"
      "titulo" => "Prolonged mechanical ventilation&#58; New facilities and new models of care"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "211"
          "paginaFinal" => "213"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "Ventila&#231;&#227;o mec&#226;nica prolongada&#58; novas instala&#231;&#245;es e novos modelos de atendimento"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "N&#46; Ambrosino"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "N&#46;"
              "apellidos" => "Ambrosino"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511512000747?idApp=UINPBA00004E"
    "url" => "/21735115/0000001800000005/v1_201305151607/S2173511512000747/v1_201305151607/en/main.assets"
  ]
  "en" => array:12 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">New perspectives in pulmonology</span>"
    "titulo" => "Long-term ventilator-dependent patients&#58; New facilities and new models of care&#46; The American perspective"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "214"
        "paginaFinal" => "216"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "G&#46; Criner"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "G&#46;"
            "apellidos" => "Criner"
            "email" => array:1 [
              0 => "crinerg&#64;tuhs&#46;temple&#46;edu"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Temple University School of Medicine&#44; Philadelphia&#44; United States"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Pacientes dependentes de ventilador a longo prazo&#58; novas instala&#231;&#245;es e novos modelos de atendimento&#46; A perspectiva Americana"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The number of patients who receive mechanical ventilation as life support is rapidly increasing due to improvements in life saving medical therapy in critically ill patients&#44; an aging population and the expanded use of aggressive surgical procedures&#46; The historic annualized increase in prolonged mechanical ventilation use in the U&#46;S&#46; is approximately 5&#46;5&#37; compared with a 1&#37; per annum increase in U&#46;S&#46; hospital admissions&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> It is estimated that the population of patients who receive prolonged mechanical ventilation in the U&#46;S&#46; will more than double by the year 2020 and reach approximately 605&#44;898 cases&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> The increased number of patients who require prolonged mechanical ventilation strains the available resources of intensive care units &#40;ICU&#41; by requiring a greater degree of medical care and ICU hospitalization that exceeds the median length of stay&#46; Mechanical ventilation is expensive therapy&#59; patients who receive ventilation in the ICU disproportionately contribute to the high cost of ICU care&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Dasta and colleagues reported that ICU patients who require mechanical ventilation compared to ICU patients who do not receive mechanical ventilation have 50&#37; higher costs and treatment with mechanical ventilation accounts for 51&#37; of their total hospital costs&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Those who require prolonged ventilation consume an even greater percentage of heath care dollars&#46; In an analysis of over 31 million hospital discharges for adults in 2003&#44; Zilberberg reported a greater median length of stay &#40;17 vs&#46; 6 days&#41; and hospital costs &#40;&#36;40&#44;903 vs&#46; &#36;13&#44;434&#41; for those who received mechanical ventilation &#8805;96<span class="elsevierStyleHsp" style=""></span>h compared to those who received mechanical ventilation &#60;96<span class="elsevierStyleHsp" style=""></span>h&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> Patients who are ventilated for &#8805;21 days have even higher costs&#59; the cost per one-year survival is &#36;423&#44;596&#44; &#36;266&#44;105 and &#36;165&#44;075 for patients ventilated &#8805;21 days&#44; &#8805;96<span class="elsevierStyleHsp" style=""></span>h with a tracheostomy and &#60;96<span class="elsevierStyleHsp" style=""></span>h&#44; respectively&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Carson reported on 126 patients ventilated &#8805;4 days with tracheostomy or &#8805;21 days without tracheostomy who were treated at one health care system and then followed prospectively for one year to determine the trajectories of their care and resource utilization&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> One hundred and three survivors &#40;82&#37;&#41; had 457 separate transitions in post discharge care location &#40;median 4 transitions&#44; including 68 patients who were readmitted at least once&#41;&#46; Patients spent an average of 74&#37; of all days either in a hospital or post acute care setting or received home health care&#46; At one year&#44; 11 patients &#40;9&#37;&#41; had a good outcome &#8211; alive without functional dependency&#44; 33 &#40;24&#37;&#41; had a moderate outcome &#8211; alive with moderate dependency and 82 &#40;65&#37;&#41; had a poor outcome&#44; either alive with complete functional dependency &#40;4 patients&#44; 21&#37;&#41; or dead &#40;56 patients&#44; 44&#37;&#41;&#46; Those with poor outcomes were older&#44; had more comorbid conditions and were more frequently discharged to a post acute care facility&#46; The mean cost per patient was &#36;306&#44;135 and for the total cohort &#36;38 million were spent for their medical care for an estimated &#36;3&#46;5 million per one independently functioning survivor at one year&#46; These data suggest that some patients who receive prolonged ventilation consume considerable resources in their last year of life with low likelihood of any meaningful quality of life&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Some reports of patients who receive prolonged ventilation&#44; however&#44; show much better outcomes&#44; both in terms of survival and quality of life&#46; Gracey and colleagues reported a 65&#37; survival at one year in patients treated in a multidisciplinary care unit&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> Chatila showed an acceptable quality of life in patients receiving prolonged ventilation of &#62;21 consecutive days with tracheostomy&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> Mamary et al&#46; recently reported in 182 consecutive patients receiving prolonged ventilation for &#62;55<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>42 days a 75&#37; one-year and 59&#37; three-year survival&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> All of these studies were conducted in special Chronic Ventilator Dependent Demonstration Units of the Health Care Financing Administration &#40;HCFA&#41; that were geared to provide long-term ventilation outside of the ICU to selected patients expected to have high likelihood of benefitting from multidisciplinary treatment plans focused on restoring functional capacity via whole body rehabilitation&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Besides the growing numbers of patients that require prolonged mechanical ventilation&#44; geographic constraints on ICU bed capacity and the high cost of care&#44; many other issues have been identified that adversely affect the plight of patients who require prolonged ventilation&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> These include&#58; the high mortality reported in patients receiving prolonged mechanical ventilation&#44; the substantial number and severity of associated comorbidities &#40;impaired cognition&#44; decreased functional status&#44; impaired swallowing&#41;&#44; the quality of life following prolonged ventilation&#44; the cost-effectiveness of care&#44; the optimal treatment plan and the best location of care&#46; Even more basic&#44; the definition of what constitutes prolonged mechanical ventilation is still a matter of debate&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The definition of prolonged ventilation has ranged from &#8805;48 consecutive hours to &#8805;96 consecutive hours with tracheostomy to &#8805;21 consecutive days with at least 6<span class="elsevierStyleHsp" style=""></span>h of ventilation daily&#46; The HCFA Chronic Ventilator Dependent Unit Demonstration Project that was conducted in the 1990s used the later definition&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> The Chronic Ventilator Dependent Unit Demonstration Project purposely selected a patient cohort who was chronically ventilated but medically stable enough not to require ongoing aggressive non-pulmonary ICU care but continued to require mechanical ventilation and needed rehabilitation to restore their functional status&#46; Patients who require mechanical ventilation for longer durations are usually older&#44; sicker&#59; receive mechanical ventilation longer before weaning attempts are begun and are more likely to have underlying COPD or pneumonia as the cause of respiratory failure&#46; Moreover&#44; they tend to have higher mortality and although fewer in number they incur longer lengths of stay and have much higher associated costs of care&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">The location of care for patients receiving prolonged ventilation in the U&#46;S&#46; migrated out of the acute care hospital in the mid 1990s due to adoption of the Prospective Payment System Designated Related Group &#40;DRG&#41; reimbursement scheme to specialized weaning centers&#44; long-term acute care hospitals or skilled nursing facilities that accept ventilated patients&#46; The Prospective Payment System utilized in the U&#46;S&#46; assigns payment scales to the care of patients who require mechanical ventilation with a tracheotomy operation performed except face&#44; neck and mouth diagnosis &#40;DRG 541&#44; &#36;89&#44; 000&#41; and mechanical ventilation &#8805;96<span class="elsevierStyleHsp" style=""></span>h without tracheotomy operation performed except face&#44; neck and mouth diagnosis &#40;DRG 542&#44; &#36;43&#44;000&#41; with the aim of bundling the cost of care and triaging differential payments for patients with higher care demands and resultant costs of care&#46; The reported patient outcomes from these long-term acute care and skilled nursing facilities have been mixed&#59; some reports show high one-year mortality with limited weaning success&#46; Patients receiving mechanical ventilation who are transferred directly from the ICU to a lower acuity facility have been reported to have a high rate of readmission and mortality&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> However&#44; the selection criteria used to admit patients to these facilities and the description and intensity of the rehabilitative and pulmonary treatment plans that are utilized by these alternative locations of care are variable and limited&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Programs that utilize a comprehensive multidisciplinary rehabilitative approach to treat patients receiving prolonged ventilation have uniformly reported better survival and functional outcomes&#46; The components of these programs that are considered essential for success&#44; include strong medical respiratory specialist leadership&#44; a multidisciplinary staff of nurses specialized in the care of ventilated patients&#44; physical and respiratory therapists&#44; speech therapists&#44; psychologists and nutritional support&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">13&#44;14</span></a> In fact several studies have demonstrated that whole body and respiratory muscle training can facilitate an increase in functional performance&#44; limb and respiratory muscle strengthening and liberation from mechanical ventilation&#46;<a class="elsevierStyleCrossRefs" href="#bib0070"><span class="elsevierStyleSup">14&#8211;16</span></a> Martin and colleagues have shown that an increase in upper extremity strength correlates better than any other spontaneous breathing variable in predicting weaning success&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">Because of the specialized needs of the patients receiving prolonged ventilation&#44; it has been suggested that regional centers of excellence may not only be more cost effective&#44; but also result in better outcomes&#46; Lone et al&#46; reviewed a database of admission to 3 UK ICUs and found that the incidence of patients requiring prolonged mechanical ventilation was 4&#46;4 per 100 ICU admissions and 6&#46;3 per ventilated ICU admission&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">17</span></a> PMV patients used 29&#46;15 of all general ICU bed days and spent a longer time in the hospital than non-PMV patients &#40;median 17 vs&#46; 7 days&#41;&#46;They suggested that a three bed weaning unit could result in cost savings and unlock ICU beds for other patients&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">17</span></a> In general&#44; outcomes from mechanical ventilation have been reported to be better when conducted at high volume rather than low volume centers&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">18</span></a> A cogent argument could be made that patients who receive prolonged ventilation need the most specialized care plan and their outcomes might be best served in regionalized centers of excellence that are dedicated to the evaluation and treatment of this patient group&#46; That conclusion was also reached after analysis of the HCFA Chronic ventilator demonstration project&#44; but limitations in funding prohibited their establishment&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Patients who require prolonged mechanical ventilation place unique demands on the health care delivery system that impacts not only those who receive that therapy but other patients who receive care in the intensive care unit or compete for medical resources in a medical care delivery system currently under duress&#46; Appropriate selection of patients receiving prolonged ventilation that may benefit from continued aggressive medical care&#44; whole body rehabilitation and continued weaning efforts is required&#44; however&#44; the complete characterization of those patients most likely to benefit still awaits identification&#46;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">19</span></a> Future research is needed to identify those patients receiving prolonged mechanical ventilation who are most likely to benefit from comprehensive and aggressive medical care from those who are dying a protracted death to optimize patient outcome and alleviate unnecessary suffering&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Conflicts of interest</span><p id="par0045" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflicts of interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:19 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Growth in adult prolonged acute mechanical ventilation&#58; implications for healthcare delivery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;D&#46; Zilberberg"
                            1 => "M&#46; de Wit"
                            2 => "J&#46;R&#46; Pirone"
                            3 => "A&#46;F&#46; Shorr"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CCM.0b013e3181691a49"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2008"
                        "volumen" => "36"
                        "paginaInicial" => "1451"
                        "paginaFinal" => "1455"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18434911"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term ventilation introduction and perspectives"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "G&#46;J&#46; Criner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Respir Care Clin N Am"
                        "fecha" => "2002"
                        "volumen" => "8"
                        "paginaInicial" => "345"
                        "paginaFinal" => "353"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12481961"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Daily cost of an intensive care unit day&#58; the contribution of mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;F&#46; Dasta"
                            1 => "T&#46;P&#46; McLaughlin"
                            2 => "S&#46;H&#46; Mody"
                            3 => "C&#46;T&#46; Piech"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2005"
                        "volumen" => "33"
                        "paginaInicial" => "1266"
                        "paginaFinal" => "1271"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15942342"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prolonged acute mechanical ventilation&#44; hospital resource utilization&#44; and mortality in the United States"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;D&#46; Zilberberg"
                            1 => "R&#46;S&#46; Luippold"
                            2 => "S&#46; Sulsky"
                            3 => "A&#46;F&#46; Shorr"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CCM.0B013E31816536F7"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2008"
                        "volumen" => "36"
                        "paginaInicial" => "724"
                        "paginaFinal" => "730"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18209667"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An economic evaluation of prolonged mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46;E&#46; Cox"
                            1 => "S&#46;S&#46; Carson"
                            2 => "J&#46;A&#46; Govert"
                            3 => "L&#46; Chelluri"
                            4 => "G&#46;D&#46; Sanders"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.CCM.0000275391.35834.10"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2007"
                        "volumen" => "35"
                        "paginaInicial" => "1918"
                        "paginaFinal" => "1927"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17581479"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A prognostic model for one-year mortality in patients requiring prolonged mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46;S&#46; Carson"
                            1 => "J&#46; Garrett"
                            2 => "L&#46;C&#46; Hanson"
                            3 => "J&#46; Lanier"
                            4 => "J&#46; Govert"
                            5 => "M&#46;C&#46; Brake"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CCM.0b013e31817b8925"
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2008"
                        "volumen" => "36"
                        "paginaInicial" => "2061"
                        "paginaFinal" => "2069"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18552692"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The chronic ventilator-dependent unit&#58; a lower-cost alternative to intensive care"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46;R&#46; Gracey"
                            1 => "D&#46;C&#46; Hardy"
                            2 => "G&#46;E&#46; Koenig"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4065/75.5.445"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mayo Clin Proc"
                        "fecha" => "2000"
                        "volumen" => "75"
                        "paginaInicial" => "445"
                        "paginaFinal" => "449"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10807071"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Quality of life in survivors of prolonged mechanical ventilatory support"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "W&#46; Chatila"
                            1 => "D&#46;T&#46; Kreimer"
                            2 => "G&#46;J&#46; Criner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2001"
                        "volumen" => "29"
                        "paginaInicial" => "737"
                        "paginaFinal" => "742"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11373458"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Survival in patients receiving prolonged ventilation&#58; factors that influence outcome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46;J&#46; Mamary"
                            1 => "S&#46; Kondapaneni"
                            2 => "G&#46;B&#46; Vance"
                            3 => "J&#46;P&#46; Gaughan"
                            4 => "U&#46;J&#46; Martin"
                            5 => "G&#46;J&#46; Criner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4137/CCRPM.S6649"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Med Insights Circ Respir Pulm Med"
                        "fecha" => "2011"
                        "volumen" => "5"
                        "paginaInicial" => "17"
                        "paginaFinal" => "26"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21573034"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Care of the patient requiring invasive mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "G&#46;J&#46; Criner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Respir Care Clin N Am"
                        "fecha" => "2002"
                        "volumen" => "8"
                        "paginaInicial" => "575"
                        "paginaFinal" => "592"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12602416"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characteristics and outcomes of ventilated patients according to time to liberation from mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "O&#46; Penuelas"
                            1 => "F&#46; Frutos-Vivar"
                            2 => "C&#46; Fernandez"
                            3 => "A&#46; Anzueto"
                            4 => "S&#46;K&#46; Epstein"
                            5 => "C&#46; Apezteguia"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.162.2.9905058"
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2011"
                        "paginaInicial" => "430"
                        "paginaFinal" => "437"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10934065"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Survivors of catastrophic illness&#58; outcome after direct transfer from intensive care to extended care facilities"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46;A&#46; Nasraway"
                            1 => "G&#46;J&#46; Button"
                            2 => "W&#46;M&#46; Rand"
                            3 => "T&#46; Hudson-Jinks"
                            4 => "M&#46; Gustafson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2000"
                        "volumen" => "28"
                        "paginaInicial" => "19"
                        "paginaFinal" => "25"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10667494"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Overview of improving tolerance of long-term mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46;J&#46; Criner"
                            1 => "A&#46; Tzouanakis"
                            2 => "D&#46;T&#46; Kreimer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Clin"
                        "fecha" => "1994"
                        "volumen" => "10"
                        "paginaInicial" => "845"
                        "paginaFinal" => "866"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8000930"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Impact of whole-body rehabilitation in patients receiving chronic mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "U&#46;J&#46; Martin"
                            1 => "L&#46; Hincapie"
                            2 => "M&#46; Nimchuk"
                            3 => "J&#46; Gaughan"
                            4 => "G&#46;J&#46; Criner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2005"
                        "volumen" => "33"
                        "paginaInicial" => "2259"
                        "paginaFinal" => "2265"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16215380"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use of inspiratory muscle strength training to facilitate ventilator weaning&#58; a series of 10 consecutive patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46;D&#46; Martin"
                            1 => "P&#46;D&#46; Davenport"
                            2 => "A&#46;C&#46; Franceschi"
                            3 => "E&#46; Harman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2002"
                        "volumen" => "122"
                        "paginaInicial" => "192"
                        "paginaFinal" => "196"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12114357"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effects of physical training on functional status in patients with prolonged mechanical ventilation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "L&#46;L&#46; Chiang"
                            1 => "L&#46;Y&#46; Wang"
                            2 => "C&#46;P&#46; Wu"
                            3 => "H&#46;D&#46; Wu"
                            4 => "Y&#46;T&#46; Wu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2522/ptj.20050036"
                      "Revista" => array:6 [
                        "tituloSerie" => "Phys Ther"
                        "fecha" => "2006"
                        "volumen" => "86"
                        "paginaInicial" => "1271"
                        "paginaFinal" => "1281"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16959675"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prolonged mechanical ventilation in critically ill patients&#58; epidemiology&#44; outcomes and modeling the potential cost consequences of establishing a regional weaning unit"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "N&#46;I&#46; Lone"
                            1 => "T&#46;S&#46; Walsh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/cc10117"
                      "Revista" => array:5 [
                        "tituloSerie" => "Crit Care"
                        "fecha" => "2011"
                        "volumen" => "15"
                        "paginaInicial" => "R102"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21439086"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Potential value of regionalized intensive care for mechanically ventilated medical patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;M&#46; Kahn"
                            1 => "W&#46;T&#46; Linde-Zwirble"
                            2 => "H&#46; Wunsch"
                            3 => "A&#46;E&#46; Barnato"
                            4 => "T&#46;J&#46; Iwashyna"
                            5 => "M&#46;S&#46; Roberts"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/rccm.200708-1214OC"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2008"
                        "volumen" => "177"
                        "paginaInicial" => "285"
                        "paginaFinal" => "291"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18006884"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Management of patients requiring prolonged mechanical ventilation&#58; report of a NAMDRC consensus conference"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "N&#46;R&#46; MacIntyre"
                            1 => "S&#46;K&#46; Epstein"
                            2 => "S&#46; Carson"
                            3 => "D&#46; Scheinhorn"
                            4 => "K&#46; Christopher"
                            5 => "S&#46; Muldoon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.128.6.3937"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2005"
                        "volumen" => "128"
                        "paginaInicial" => "3937"
                        "paginaFinal" => "3954"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16354866"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735115/0000001800000005/v1_201305151607/S2173511512000759/v1_201305151607/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9738"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "New perspectives in Pulmonology"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001800000005/v1_201305151607/S2173511512000759/v1_201305151607/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511512000759?idApp=UINPBA00004E"
]
Article information
ISSN: 21735115
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 7 7 14
2024 October 28 31 59
2024 September 30 25 55
2024 August 36 30 66
2024 July 34 37 71
2024 June 23 26 49
2024 May 28 30 58
2024 April 28 27 55
2024 March 23 21 44
2024 February 22 25 47
2024 January 15 30 45
2023 December 20 25 45
2023 November 21 30 51
2023 October 14 35 49
2023 September 19 29 48
2023 August 23 24 47
2023 July 18 25 43
2023 June 14 18 32
2023 May 21 21 42
2023 April 6 9 15
Show all

Follow this link to access the full text of the article

Pulmonology

Are you a health professional able to prescribe or dispense drugs?