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Letter to the Editor
Unexplained pulmonary hypertension in peritoneal dialysis and hemodialysis patients
Hipertensão pulmonar inexplicável em pacientes em diálise peritoneal e hemodiálise
H. Nasri
Department of Nephrology, Isfahan University of Medical Sciences, Isfahan, Iran
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    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Unexplained pulmonary hypertension in peritoneal dialysis and hemodialysis patients"
    "tieneTextoCompleto" => true
    "saludo" => "Dear Editor&#44;"
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    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "H&#46; Nasri"
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            "nombre" => "H&#46;"
            "apellidos" => "Nasri"
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            "entidad" => "Department of Nephrology&#44; Isfahan University of Medical Sciences&#44; Isfahan&#44; Iran"
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    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Hipertens&#227;o pulmonar inexplic&#225;vel em pacientes em di&#225;lise peritoneal e hemodi&#225;lise"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We read with great interest the nice article by Etemadi and colleagues&#44; in your journal&#44; <span class="elsevierStyleItalic">Revista Portuguesa de Pneumologia</span>&#44; entitled &#8220;Unexplained pulmonary hypertension in peritoneal dialysis and hemodialysis patients&#8221;&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> In a retrospective study of chronic hemodialysis and peritoneal dialysis patients&#44; pulmonary hypertension was found in 14 &#40;41&#46;1&#37;&#41; patients of the hemodialysis group and in 6 &#40;18&#46;7&#37;&#41; patients of the peritoneal dialysis group&#44; where pulmonary hypertension was defined as a systolic pulmonary artery pressure &#40;SPAP&#41;<span class="elsevierStyleHsp" style=""></span>&#8805;<span class="elsevierStyleHsp" style=""></span>35<span class="elsevierStyleHsp" style=""></span>mmHg&#46; They concluded that unexplained pulmonary hypertension seems to be more frequent in patients undergoing hemodialysis than with patients in the peritoneal dialysis group&#46; In this context&#44; I would like to make a few points about pulmonary hypertension in dialysis patients&#46; In a study of 102 maintenance hemodialysis patients&#44; we found pulmonary artery pressure of 41&#46;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>12&#46;6<span class="elsevierStyleHsp" style=""></span>mmHg&#46; In our study&#44; 76&#46;5&#37; of hemodialysis patients had SPAP<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>35<span class="elsevierStyleHsp" style=""></span>mmHg&#46; In this study we can also see that pulmonary artery pressure had significant positive correlation with the duration and degree of hemodialysis&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> In another study we also observed that pulmonary artery pressure had significant positive correlation with serum intact parathormone&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Pulmonary arterial hypertension is a serious cardiac complication among patients with end-stage kidney disease&#44; especially patients on hemodialysis as mentioned in the study by Etemadi et al&#46;&#44; and we need to look for other aggravating factors among dialysis patients&#46;<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3&#8211;5</span></a> In order to achieve better understanding about this aspect of dialysis patients&#44; more clinical studies are suggested&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Ethical disclosures</span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Protection of human and animal subjects</span><p id="par0010" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Confidentiality of data</span><p id="par0015" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Right to privacy and informed consent</span><p id="par0020" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conflicts of interest</span><p id="par0025" class="elsevierStylePara elsevierViewall">The author has no conflicts of interest to declare&#46;</p></span></span>"
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ISSN: 21735115
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Pulmonology

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