Statistics

 array:24 [
  "pii" => "S2173511515002055"
  "issn" => "21735115"
  "doi" => "10.1016/j.rppnen.2015.12.002"
  "estado" => "S300"
  "fechaPublicacion" => "2016-05-01"
  "aid" => "1121"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2015"
  "documento" => "simple-article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "cor"
  "cita" => "Rev Port Pneumol. 2016;22:183"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1456
    "formatos" => array:3 [
      "EPUB" => 195
      "HTML" => 754
      "PDF" => 507
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S2173511515001864"
    "issn" => "21735115"
    "doi" => "10.1016/j.rppnen.2015.10.006"
    "estado" => "S300"
    "fechaPublicacion" => "2016-05-01"
    "aid" => "1106"
    "documento" => "simple-article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "cor"
    "cita" => "Rev Port Pneumol. 2016;22:184"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1488
      "formatos" => array:3 [
        "EPUB" => 203
        "HTML" => 762
        "PDF" => 523
      ]
    ]
    "en" => array:9 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "COPD&#58; Are we using all the tools we have&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "184"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; Ara&#250;jo"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Ara&#250;jo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511515001864?idApp=UINPBA00004E"
    "url" => "/21735115/0000002200000003/v1_201605310123/S2173511515001864/v1_201605310123/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173511516000099"
    "issn" => "21735115"
    "doi" => "10.1016/j.rppnen.2016.01.002"
    "estado" => "S300"
    "fechaPublicacion" => "2016-05-01"
    "aid" => "1132"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "simple-article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "cor"
    "cita" => "Rev Port Pneumol. 2016;22:181-2"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1307
      "formatos" => array:3 [
        "EPUB" => 193
        "HTML" => 624
        "PDF" => 490
      ]
    ]
    "en" => array:9 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Research Letter</span>"
      "titulo" => "Critical appraisal of the Portuguese clinical guideline 28&#47;2011"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "181"
          "paginaFinal" => "182"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "T&#46; Sousa-Veloso"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "T&#46;"
              "apellidos" => "Sousa-Veloso"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511516000099?idApp=UINPBA00004E"
    "url" => "/21735115/0000002200000003/v1_201605310123/S2173511516000099/v1_201605310123/en/main.assets"
  ]
  "en" => array:13 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Clinical trials in Portugal&#58; A ruby in the middle of the rubble"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "183"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "J&#46;C&#46; Winck"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "J&#46;C&#46;"
            "apellidos" => "Winck"
            "email" => array:1 [
              0 => "jcwinck&#64;mail&#46;telepac&#46;pt"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Faculty of Medicine&#44; Porto University&#44; Portugal"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 934
            "Ancho" => 1591
            "Tamanyo" => 84043
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical trials in COPD including Portuguese centres &#40;2006&#8211;2015&#41;&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The decrease in the number of clinical trials held in Portugal shows a loss of competiveness that is disturbing&#46; We should focus on measures that may recover the implementation of a dynamic clinical investigation field&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">According to a study of the Portuguese Association of Pharmaceutical Industry &#40;APIFARMA&#41; published in 2013<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> there has been a tendency towards stagnation in the number of Clinical trials &#40;CT&#41; in Portugal&#46; Nevertheless&#44; in 2012 the market value of CT in Portugal was &#8364;36 millions&#46; Looking at the sites where the CT were performed&#44; between 2006 and 2011&#44; Coimbra University Hospital Centre &#40;CHUC&#41; with 158 CT&#44; North Lisbon Hospital Centre &#40;CHLN&#41; with 135 and S&#227;o Jo&#227;o Hospital Centre &#40;CHSJ&#41; with 98 were the top 3 institutions&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Compared to Cardiology with 34 CT from 2009 until 2012&#44; Pulmonology had only 15&#46; Compared with other countries&#44; in 2010 Portugal had one of the lowest numbers of CT per million inhabitants&#44; with 10 compared with Czech Republic&#44; which achieved 47&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">2</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Recently the EU has developed a register for all the Clinical trials performed in Europe&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">3</span></a> Analysing the participation of Portuguese centres in the area of Pulmonology from 2006 to 2015&#44; the scenario is also not very optimistic&#44; with a total of 15 trials on COPD&#44; 7 in Cystic Fibrosis &#40;CF&#41;&#44; 55 in Lung Cancer &#40;LC&#41; and 6 in Idiopathic Pulmonary Fibrosis &#40;IPF&#41;&#46; This is a long way from the involvement of Greece and the Czech Republic with&#44; respectively&#44; 28 and 68 CT on COPD&#44; 4 and 13 CT on CF&#44; 77 and 107 on LC and 6 and 12 on IPF&#46; Moreover&#44; analysing the participation of Portuguese centres in CT on COPD &#40;a disease with the highest number of patients included in CT&#41; over the last 10 years &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#44; there is an irregular pattern with a minimum of 0 in 2012 and a maximum of 4 in 2014&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">What can we do to improve&#63;</p><p id="par0030" class="elsevierStylePara elsevierViewall">By doing Clinical trials we will generate better quality data to support our decisions in healthcare&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Scientific societies should have a stronger commitment to the promotion and support of the clinical investigation in Portugal&#46; By helping to network with European countries it will facilitate internationalization and improvement in science&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Through the creation of dedicated structures and enhancement of cooperation between Portuguese centres the results will appear in the future&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Models that include incentives for the participation of researchers and other medical professionals should be common practice&#46; Investigator-driven CT should be also encouraged and welcomed&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">If we succeed in improving these figures&#44; the Portuguese economy will be stronger&#44; we will increase our small footprint in the European respiratory science and our specialty will have a higher profile&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0055" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflicts of interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "multimedia" => array:1 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 934
            "Ancho" => 1591
            "Tamanyo" => 84043
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical trials in COPD including Portuguese centres &#40;2006&#8211;2015&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:3 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "titulo" => "Study on Clinical trials in Portugal"
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:2 [
                        "fecha" => "2013"
                        "editorial" => "Associa&#231;&#227;o Portuguesa da Ind&#250;stria Farmac&#234;utica &#40;APIFARMA&#41;"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "APIFARMA&#44; Desafios da Sa&#250;de em Portugal 2013&#44; 20 Mar&#231;o"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "Price Waterhouse Coopers"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:1 [
                        "fecha" => "2013"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "EU Clinical Trials Register&#46; <a id="intr0015" class="elsevierStyleInterRef" href="https://www.clinicaltrialsregister.eu/ctr-search/search">https&#58;&#47;&#47;www&#46;clinicaltrialsregister&#46;eu&#47;ctr-search&#47;search</a>&#46;"
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735115/0000002200000003/v1_201605310123/S2173511515002055/v1_201605310123/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "20584"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letters to the Editor"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735115/0000002200000003/v1_201605310123/S2173511515002055/v1_201605310123/en/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511515002055?idApp=UINPBA00004E"
]