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Vol. 16. Issue 3.
Pages 477-482 (May - June 2010)
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Vol. 16. Issue 3.
Pages 477-482 (May - June 2010)
Caso Clínico/Case Report
Open Access
Hemangioendotelioma epitelióide da pleura – Uma apresentação rara a propósito de um caso clínico
Epithelioid hemangioendothelioma of the pleura – A rare presentation of a clinical case
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Sónia André1, Carla Valente1, Benedita Paiva2, Alice Pêgo3, Lina Carvalho4, A. Segorbe Luís5
1 Interna do Internato Complementar de Pneumologia, Faculdade de Medicina, Universidade de Coimbra, Departamento de Ciências Pneumológicas e Alergológicas dos Hospitais da Universidade de Coimbra, Av. Bissaya Barreto e Praceta Prof. Mota Pinto, 3000-075 Coimbra
2 Assistente Hospitalar de Pneumologia, Faculdade de Medicina, Universidade de Coimbra, Departamento de Ciências Pneumológicas e Alergológicas dos Hospitais da Universidade de Coimbra, Av. Bissaya Barreto e Praceta Prof. Mota Pinto, 3000-075 Coimbra
3 Assistente Graduada de Pneumologia, Faculdade de Medicina, Universidade de Coimbra, Departamento de Ciências Pneumológicas e Alergológicas dos Hospitais da Universidade de Coimbra, Av. Bissaya Barreto e Praceta Prof. Mota Pinto, 3000-075 Coimbra
4 Professora de Anatomia Patológica da FMUC e Chefe de Serviço de Anatomia Patológica dos HUC, Faculdade de Medicina, Universidade de Coimbra, Departamento de Ciências Pneumológicas e Alergológicas dos Hospitais da Universidade de Coimbra, Av. Bissaya Barreto e Praceta Prof. Mota Pinto, 3000-075 Coimbra
5 Professor de Pneumologia da FMUC e Chefe de Serviço de Pneumologia dos HUC, Faculdade de Medicina, Universidade de Coimbra, Departamento de Ciências Pneumológicas e Alergológicas dos Hospitais da Universidade de Coimbra, Av. Bissaya Barreto e Praceta Prof. Mota Pinto, 3000-075 Coimbra
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Resumo

O hemangioendotelioma epitelióide (HEE) é um tumor de origem vascular, de grau intermédio de malignidade, cuja apresentação primária na pleura é rara. Pelo reduzido número de casos descritos na literatura, os autores apresentam o caso de uma doente de 65 anos, que recorreu ao serviço de urgência por toracalgia à direita, com sete meses de evolução, na sequência de um traumatismo torácico. Radiologicamente apresentava sinais sugestivos de derrame pleural direito de volume moderado. A biópsia pleuropulmonar, efectuada por toracotomia, permitiu estabelecer o diagnóstico histológico de HEE da pleura.

Atendendo ao estádio localmente avançado do tumor, a doente iniciou quimioterapia com carboplatina e etoposido, tendo falecido 6 meses após o diagnóstico. Constata-se, com este caso, que a manifestação pleural do HEE tem um comportamento agressivo, semelhante ao do angiossarcoma, com uma sobrevida de apenas alguns meses após o diagnóstico.

Rev Port Pneumol 2010; XVI (3): 477-482

Palavras-chave:
Hemangioendotelioma
tumor vascular
pleura
Abstract

Epithelioid Hemangioendothelioma (EHE) is a vascular tumour with rare pleural presentation. As there are a small number of cases described in the literature the authors present the case of a 65-year-old woman, who was admitted to the Emergency Department for a right-sided chest pain, which progressed over 7 months, after a thoracic trauma. The chest X-ray showed signs of a moderate right-sided pleural effusion. A pleural-pulmonary biopsy carried out by toracotomy established the histological diagnosis of EHE of the pleura.

Due to the locally advanced stage of the tumour, chemotherapy with carboplatin and etoposide was prescribed and the patient died 6 months later.

This case confirms that pleural EHE has an aggressivebehaviour, similar to an angiossarcoma, with a median survival of only a few months after diagnosis.

Rev Port Pneumol 2010; XVI (3): 477-482

Key-words:
Haemangioendotelioma
vascular tumour
pleura
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Bibliografia
[1.]
P. Bagan, M. Hassan, F.L.P. Barthes, S. Peyrard, R. Souilamas, C. Danel, M. Riquet.
Prognostic factors and surgical indications of pulmonary epithelioid hemangioendothelioma: a review of the literature.
Ann Thorac Surg, 82 (2006), pp. 2010-2013
[2.]
M. Al-Shraim, B. Mahboud, P.C. Neligan, D. Chamberlain, D. Ghazarian.
Primary pleural epithelioid haemangioendothelioma with metastases to the skin-a case report and literature review.
J Clin Pathol, 58 (2005), pp. 107-109
[3.]
A. Oliveira, L. Carvalho.
Epithelioid haemangioendothelioma of the pleura: 29 months survival.
Rev Port Pneumol, 12 (2006), pp. 455-461
[4.]
P. Zhang, V. Livolsi, J. Brooks.
Malignant epithelioid vascular tumors of the pleura – report of a series and literature review.
Human Pathology, 31 (2000), pp. 29-34
[5.]
F. Bevelaqua, Q. Valensi, D. Hulnick.
Epithelioid hemangioendothelioma – A rare tumour with variable prognosis as a pleural effusion.
Chest, 3 (1993), pp. 302-665
[6.]
C. Pinet, A. Magnan, L. Garbe, M. Payan, D. Vervloet.
Aggressive form of pleural epithelioid haemangioendothelioma – complete response after chemotherapy.
Eur Respir J, 14 (1999), pp. 237-238
[7.]
M. Kitaichi, S. Nagai, K. Nishimura, H. Itoh, H. Asamoto, T. Izumi, D. Dail.
Pulmonary epithelioid haemangioendothelioma in 21 patients, including three with partial spontaneous regression.
Eur Resp J, 12 (1998), pp. 89-96
[8.]
G.A. Rossi, P. Tomà, O. Sacco, B. Fregonese, E. Podestà, P. Dodero, G. Silvestri, C. Gambini.
A 14yr-old male with dyspnoea, productive cough and chest pain.
Eur Respir J, 22 (2003), pp. 387-391
[9.]
N. Sakamoto, S. Adachi, S. Monzawa, A. Hamanaka, Y. Takada, Y. Hunada, Y. Kotani, K. Hanioka.
High resolution CT findings of pulmonary epithelioid Hemangioendothelioma – Case report.
J Thorac Imaging, 20 (2005), pp. 236-238
[10.]
M.J. Palomo-González, M.D. Toledo-Coelho, J. Pérez-Requena, N. García-Gomez, M.J. Añon-Requena.
Hemangioendotelioma epitelioide de pulmón – presentación de un caso con hemoptisis masiva.
Rev Esp Patol, 35 (2002), pp. 341-344
[11.]
E.J. Crotty, H.P. Mcadams, J.J. Erasmus, T.A. Sporn, V.L. Roggli.
Epithelioid hemangioendothelioma of the pleura: clinical and radiologic features.
AJR, 175 (2000), pp. 1545-1549
[12.]
P. Cronin, D. Arenberg.
Pulmonary epithelioid hemangioendothelioma – an unusual case and review of the literature.
Chest, 125 (2004), pp. 789-793
[13.]
P.K. Vitório, E.M. Coletta, N. Morrone, C.H. Lima, J.C. Guilherme, D. Inoue, F.B. Hernandes.
Pleural epithelioid hemangioendothelioma – Case report.
J Bras Pneumol, 30 (2004), pp. 60-65
[14.]
D. Sterman, L.A. Litzky, S.M. Albelda.
Disorders of the pleural space, malignant mesothelioma and other primary pleural tumors.
4th edn, pp. 1551-1552
[15.]
M.S. Roh, J.Y. Seo, S.H. Hong.
Epithelioid angiosarcoma of the pleura – A case report.
J Korean Med Sci, 16 (2001), pp. 792-795
Copyright © 2010. Sociedade Portuguesa de Pneumologia/SPP
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