array:23 [
  "pii" => "S2173511506703906"
  "issn" => "21735115"
  "doi" => "10.1016/S2173-5115(06)70390-6"
  "estado" => "S300"
  "fechaPublicacion" => "2006-01-01"
  "aid" => "70390"
  "copyright" => "Sociedade Portuguesa de Pneumologia"
  "copyrightAnyo" => "2006"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "fla"
  "cita" => "Rev Port Pneumol. 2006;12:79-84"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3230
    "formatos" => array:3 [
      "EPUB" => 205
      "HTML" => 1851
      "PDF" => 1174
    ]
  ]
  "itemAnterior" => array:19 [
    "pii" => "S217351150670389X"
    "issn" => "21735115"
    "doi" => "10.1016/S2173-5115(06)70389-X"
    "estado" => "S300"
    "fechaPublicacion" => "2006-01-01"
    "aid" => "70389"
    "copyright" => "Sociedade Portuguesa de Pneumologia"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Rev Port Pneumol. 2006;12:71-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3295
      "formatos" => array:3 [
        "EPUB" => 236
        "HTML" => 1766
        "PDF" => 1293
      ]
    ]
    "pt" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Ruptura iatrogénica da traqueia: Caso clínico e indicações para tratamento conservador"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "pt"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "71"
          "paginaFinal" => "78"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Iatrogenic tracheal rupture: A case report and indications for conservative management"
        ]
      ]
      "contieneResumen" => array:2 [
        "pt" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Miguel S. Guerra, José António Miranda, António Caiado, José Almeida, João Moura e Sá, Francisco Leal, Luís Vouga"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "Miguel S."
              "apellidos" => "Guerra"
            ]
            1 => array:2 [
              "nombre" => "José"
              "apellidos" => "António Miranda"
            ]
            2 => array:2 [
              "nombre" => "António"
              "apellidos" => "Caiado"
            ]
            3 => array:2 [
              "nombre" => "José"
              "apellidos" => "Almeida"
            ]
            4 => array:2 [
              "nombre" => "João"
              "apellidos" => "Moura e Sá"
            ]
            5 => array:2 [
              "nombre" => "Francisco"
              "apellidos" => "Leal"
            ]
            6 => array:2 [
              "nombre" => "Luís"
              "apellidos" => "Vouga"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217351150670389X?idApp=UINPBA00004E"
    "url" => "/21735115/0000001200000001/v1_201305151418/S217351150670389X/v1_201305151418/pt/main.assets"
  ]
  "pt" => array:14 [
    "idiomaDefecto" => true
    "titulo" => "Hidroxicloroquina na hemossiderose pulmonar idiopática – Caso clínico"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "79"
        "paginaFinal" => "84"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Marta Pinto de Almeida, Guilhermina Reis, Margarida Guedes"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "Marta Pinto"
            "apellidos" => "de Almeida"
            "email" => array:1 [
              0 => "martaipalmeida@hotmail.com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Guilhermina"
            "apellidos" => "Reis"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">2</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Margarida"
            "apellidos" => "Guedes"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">3</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Interna Complementar de Pediatria &#8211; Servi&#231;o de Pediatria&#44; Hospital Geral de Santo Ant&#243;nio&#44; SA"
            "etiqueta" => "<span class="elsevierStyleSup">1</span>"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Assistente Hospitalar &#8211; Servi&#231;o de Pediatria&#44; Hospital Geral de Santo Ant&#243;nio&#44; SA"
            "etiqueta" => "<span class="elsevierStyleSup">2</span>"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Assistente Hospitalar Graduada &#8211; Servi&#231;o de Pediatria&#44; Hospital Geral de Santo Ant&#243;nio&#44; SA"
            "etiqueta" => "<span class="elsevierStyleSup">3</span>"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Correspond&#234;ncia&#58; Servi&#231;o de Pediatria&#58; Director de Servi&#231;o &#8211; Dr&#46;&#170; Margarida Medina&#44; Hospital Geral de Santo Ant&#243;nio&#44; SA&#44; Largo Professor Abel Salazar&#44; 4050-011 Porto&#44; Telem&#243;vel &#8211; 934212256&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Hydroxychloroquine in pediatric idiopathic pulmonary hemosiderosis &#8211; A case report"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2005-10-16"
    "fechaAceptado" => "2005-11-28"
    "PalabrasClave" => array:2 [
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras-chave"
          "identificador" => "xpalclavsec158573"
          "palabras" => array:4 [
            0 => "Hemossiderose pulmonar idiop&#225;tica"
            1 => "hidroxicloroquina"
            2 => "vacina <span class="elsevierStyleItalic">influenza</span>"
            3 => "crian&#231;as"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key-words"
          "identificador" => "xpalclavsec158572"
          "palabras" => array:4 [
            0 => "Idiopathic pulmonary hemosiderosis"
            1 => "hydroxychloroquine"
            2 => "<span class="elsevierStyleItalic">influenza</span> vaccine"
            3 => "children"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "pt" => array:2 [
        "titulo" => "Resumo"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Os autores apresentam o caso de uma crian&#231;a com hemossiderose pulmonar idiop&#225;tica grave&#44; que&#44; ap&#243;s ter iniciado tratamento com hidroxicloroquina&#44; apresentou altera&#231;&#227;o do seu curso cl&#237;nico&#44; com melhoria significativa e duradoura&#46; A efic&#225;cia desta terap&#234;utica &#233; salientada&#46; Reportam ainda a ocorr&#234;ncia de exacerba&#231;&#227;o cl&#237;nica&#44; com hemoptise&#44; ap&#243;s administra&#231;&#227;o de vacina antigripal&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The authors present the case of a child with severe idiopathic pulmonary hemosiderosis who after having begun treatment with hydroxychloroquine had a significant and lasting improvement&#46; The efficacy of this therapeutic is pointed out&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">They also report the occurrence of clinical exacerbation&#44; with hemoptysis&#44; after receiving an influenza vaccine&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:16 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary hemosiderosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46;C&#46; Heiner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Disorders of the respiratory tract in children"
                        "paginaInicial" => "498"
                        "paginaFinal" => "509"
                        "serieFecha" => "1990"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Neese LW&#44; Rosenow EC&#44; Myers JL&#46; Pulmonary Hemosiderosis&#46; <span class="elsevierStyleItalic">In</span> Alan R&#46; Leff &#40;eds&#41;&#46; Pulmonary and Critical Care Pharmacology and Therapeutics 1996&#58;1111-6&#46;"
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Idiopathic pulmonary haemosiderosis revisited"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "O&#46;C&#46; Ioachimescu"
                            1 => "S&#46; Sieber"
                            2 => "A&#46; Kotch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2004"
                        "volumen" => "24"
                        "numero" => "1"
                        "paginaInicial" => "162"
                        "paginaFinal" => "170"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15293620"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chloroquine in idiopathic pulmonary hemosiderosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; Bush"
                            1 => "M&#46;N&#46; Sheppard"
                            2 => "J&#46;O&#46; Warner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dis Child"
                        "fecha" => "1992"
                        "volumen" => "67"
                        "paginaInicial" => "625"
                        "paginaFinal" => "627"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1599302"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hemossiderose Pulmonar&#58; Revis&#227;o Casu&#237;stica da Consulta de Hematologia Pedi&#225;trica do Hospital de Dona Estef&#226;nia Durante o Per&#237;odo 1976&#8211;1994"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "S&#46; Lamy"
                            1 => "L&#46; Braga"
                            2 => "J&#46;O&#46; Santos"
                            3 => "M&#46;G&#46;G&#46;C&#46; Costa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Ped Port"
                        "fecha" => "1995"
                        "volumen" => "26"
                        "paginaInicial" => "151"
                        "paginaFinal" => "155"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term course of patients with idiopathic pulmonary hemosiderosis &#40;1979-1994&#41;&#58; prolonged survival with low-dose corticosteroid therapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "N&#46; Kiper"
                            1 => "A&#46; Go&#231;men"
                            2 => "U&#46; Ozcelik"
                            3 => "E&#46; Dilber"
                            4 => "D&#46; Anadol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Pulmonol"
                        "fecha" => "1999"
                        "volumen" => "27"
                        "paginaInicial" => "180"
                        "paginaFinal" => "184"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10213256"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prognosis in pediatric idiopathic pulmonary hemosiderosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46;M&#46; Saeed"
                            1 => "M&#46;S&#46; Woo"
                            2 => "E&#46;F&#46; MacLaughlin"
                            3 => "M&#46;F&#46; Margetis"
                            4 => "T&#46;G&#46; Keens"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1999"
                        "volumen" => "116"
                        "paginaInicial" => "721"
                        "paginaFinal" => "725"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10492278"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Idiopathic pulmonary hemosiderosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "T&#46; Dua"
                            1 => "J&#46; Chandra"
                            2 => "M&#46; Jain"
                            3 => "S&#46;M&#46; Passah"
                            4 => "A&#46;K&#46; Dutta"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Indian J Pediatr"
                        "fecha" => "2000"
                        "volumen" => "67"
                        "numero" => "9"
                        "paginaInicial" => "693"
                        "paginaFinal" => "694"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11028126"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term outcome of idiopathic pulmonary hemosiderosis in children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:14 [
                            0 => "L&#46; Le Clainche"
                            1 => "M&#46; Le Bourgeois"
                            2 => "B&#46; Fauroux"
                            3 => "N&#46; Forenza"
                            4 => "J&#46;P&#46; Dommergues"
                            5 => "J&#46;C&#46; Desbois"
                            6 => "G&#46; Bellon"
                            7 => "J&#46; Derelle"
                            8 => "G&#46; Dutau"
                            9 => "C&#46; Marguet"
                            10 => "I&#46; Pin"
                            11 => "I&#46; Tillie-Leblond"
                            12 => "P&#46; Scheinmann"
                            13 => "J&#46; De Blic"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Medicine &#40;Baltimore&#41;"
                        "fecha" => "2000"
                        "volumen" => "79"
                        "numero" => "5"
                        "paginaInicial" => "318"
                        "paginaFinal" => "326"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effectiveness of chloroquine therapy in idiopathic pulmonary hemosiderosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Zaki"
                            1 => "Q&#46; Al Saleh"
                            2 => "G&#46; Al Mutari"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Pulmonol"
                        "fecha" => "1995"
                        "volumen" => "20"
                        "paginaInicial" => "125"
                        "paginaFinal" => "126"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8570303"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hemossiderose Pulmonar Idiop&#225;tica &#8211; caso cl&#237;nico"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "M&#46; Pinto"
                            1 => "J&#46; Correia"
                            2 => "I&#46; Leal"
                            3 => "A&#46; Reis"
                            4 => "B&#46; Le&#227;o"
                            5 => "S&#46; Carvalho"
                            6 => "C&#46;S&#46; Soares"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Med Port"
                        "fecha" => "1996"
                        "volumen" => "9"
                        "paginaInicial" => "41"
                        "paginaFinal" => "44"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8638475"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Idiopathic pulmonary hemosiderosis&#58; a case report"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "G&#46;F&#46; Ferrari"
                            1 => "J&#46;R&#46; Fioretto"
                            2 => "A&#46;F&#46;R&#46; Alves"
                            3 => "G&#46;S&#46; Brand&#227;o"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Pediatr &#40;Rio J&#41;"
                        "fecha" => "2000"
                        "volumen" => "76"
                        "numero" => "2"
                        "paginaInicial" => "149"
                        "paginaFinal" => "152"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Treatment of Pediatric Idiopathic Pulmonary Hemosiderosis with Low-Dose Cyclophosphamide"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;-H&#46; Huang"
                            1 => "P&#46;-Y&#46; Lee"
                            2 => "C&#46;-K&#46; Niu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1345/aph.1D042"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Pharmacother"
                        "fecha" => "2000"
                        "volumen" => "37"
                        "paginaInicial" => "1618"
                        "paginaFinal" => "1621"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14565801"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pneumonia e Anemia Grave &#8211; caso cl&#237;nico"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46;G&#46; Reis"
                            1 => "F&#46; Teixeira"
                            2 => "G&#46; Costa"
                            3 => "M&#46; Guedes"
                            4 => "F&#46;P&#46; Silva"
                            5 => "M&#46; Tavares"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nascer e Crescer"
                        "fecha" => "2000"
                        "volumen" => "9"
                        "numero" => "4"
                        "paginaInicial" => "246"
                        "paginaFinal" => "251"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pitfalls in the diagnosis of idiopathic pulmonary haemosiderosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "T&#46;-C&#46; Yao"
                            1 => "I&#46;-J&#46; Hung"
                            2 => "T&#46;-H&#46; Jaing"
                            3 => "C&#46;-P&#46; Yang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dis Child"
                        "fecha" => "2002"
                        "volumen" => "86"
                        "paginaInicial" => "436"
                        "paginaFinal" => "438"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12023180"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary Hemorrhage&#47;Hemoptysis in Children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "S&#46; Godfrey"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/ppul.20020"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Pulmonol"
                        "fecha" => "2004"
                        "volumen" => "37"
                        "paginaInicial" => "476"
                        "paginaFinal" => "484"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15114547"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "pt"
  "url" => "/21735115/0000001200000001/v1_201305151418/S2173511506703906/v1_201305151418/pt/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9550"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case Report&#47;Caso Cl&#237;nico"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735115/0000001200000001/v1_201305151418/S2173511506703906/v1_201305151418/pt/main.pdf?idApp=UINPBA00004E&text.app=https://journalpulmonology.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173511506703906?idApp=UINPBA00004E"
]
Share
Journal Information
Vol. 12. Issue 1.
Pages 79-84 (January - February 2006)
Share
Share
Download PDF
More article options
Vol. 12. Issue 1.
Pages 79-84 (January - February 2006)
Full text access
Hidroxicloroquina na hemossiderose pulmonar idiopática – Caso clínico
Hydroxychloroquine in pediatric idiopathic pulmonary hemosiderosis – A case report
Visits
860
Marta Pinto de Almeida1,
Corresponding author
martaipalmeida@hotmail.com

Correspondência: Serviço de Pediatria: Director de Serviço – Dr.ª Margarida Medina, Hospital Geral de Santo António, SA, Largo Professor Abel Salazar, 4050-011 Porto, Telemóvel – 934212256.
, Guilhermina Reis2, Margarida Guedes3
1 Interna Complementar de Pediatria – Serviço de Pediatria, Hospital Geral de Santo António, SA
2 Assistente Hospitalar – Serviço de Pediatria, Hospital Geral de Santo António, SA
3 Assistente Hospitalar Graduada – Serviço de Pediatria, Hospital Geral de Santo António, SA
This item has received
Article information
Resumo

Os autores apresentam o caso de uma criança com hemossiderose pulmonar idiopática grave, que, após ter iniciado tratamento com hidroxicloroquina, apresentou alteração do seu curso clínico, com melhoria significativa e duradoura. A eficácia desta terapêutica é salientada. Reportam ainda a ocorrência de exacerbação clínica, com hemoptise, após administração de vacina antigripal.

Palavras-chave:
Hemossiderose pulmonar idiopática
hidroxicloroquina
vacina influenza
crianças
Abstract

The authors present the case of a child with severe idiopathic pulmonary hemosiderosis who after having begun treatment with hydroxychloroquine had a significant and lasting improvement. The efficacy of this therapeutic is pointed out.

They also report the occurrence of clinical exacerbation, with hemoptysis, after receiving an influenza vaccine.

Key-words:
Idiopathic pulmonary hemosiderosis
hydroxychloroquine
influenza vaccine
children
Full text is only aviable in PDF
Bibliografia
[1.]
D.C. Heiner.
Pulmonary hemosiderosis.
Disorders of the respiratory tract in children, pp. 498-509
[2.]
Neese LW, Rosenow EC, Myers JL. Pulmonary Hemosiderosis. In Alan R. Leff (eds). Pulmonary and Critical Care Pharmacology and Therapeutics 1996:1111-6.
[3.]
O.C. Ioachimescu, S. Sieber, A. Kotch.
Idiopathic pulmonary haemosiderosis revisited.
Eur Respir J, 24 (2004), pp. 162-170
[4.]
A. Bush, M.N. Sheppard, J.O. Warner.
Chloroquine in idiopathic pulmonary hemosiderosis.
Arch Dis Child, 67 (1992), pp. 625-627
[5.]
S. Lamy, L. Braga, J.O. Santos, M.G.G.C. Costa.
Hemossiderose Pulmonar: Revisão Casuística da Consulta de Hematologia Pediátrica do Hospital de Dona Estefânia Durante o Período 1976–1994.
Acta Ped Port, 26 (1995), pp. 151-155
[6.]
N. Kiper, A. Goçmen, U. Ozcelik, E. Dilber, D. Anadol.
Long-term course of patients with idiopathic pulmonary hemosiderosis (1979-1994): prolonged survival with low-dose corticosteroid therapy.
Pediatr Pulmonol, 27 (1999), pp. 180-184
[7.]
M.M. Saeed, M.S. Woo, E.F. MacLaughlin, M.F. Margetis, T.G. Keens.
Prognosis in pediatric idiopathic pulmonary hemosiderosis.
Chest, 116 (1999), pp. 721-725
[8.]
T. Dua, J. Chandra, M. Jain, S.M. Passah, A.K. Dutta.
Idiopathic pulmonary hemosiderosis.
Indian J Pediatr, 67 (2000), pp. 693-694
[9.]
L. Le Clainche, M. Le Bourgeois, B. Fauroux, N. Forenza, J.P. Dommergues, J.C. Desbois, G. Bellon, J. Derelle, G. Dutau, C. Marguet, I. Pin, I. Tillie-Leblond, P. Scheinmann, J. De Blic.
Long-term outcome of idiopathic pulmonary hemosiderosis in children.
Medicine (Baltimore), 79 (2000), pp. 318-326
[10.]
M. Zaki, Q. Al Saleh, G. Al Mutari.
Effectiveness of chloroquine therapy in idiopathic pulmonary hemosiderosis.
Pediatr Pulmonol, 20 (1995), pp. 125-126
[11.]
M. Pinto, J. Correia, I. Leal, A. Reis, B. Leão, S. Carvalho, C.S. Soares.
Hemossiderose Pulmonar Idiopática – caso clínico.
Acta Med Port, 9 (1996), pp. 41-44
[12.]
G.F. Ferrari, J.R. Fioretto, A.F.R. Alves, G.S. Brandão.
Idiopathic pulmonary hemosiderosis: a case report.
J Pediatr (Rio J), 76 (2000), pp. 149-152
[13.]
S.-H. Huang, P.-Y. Lee, C.-K. Niu.
Treatment of Pediatric Idiopathic Pulmonary Hemosiderosis with Low-Dose Cyclophosphamide.
Ann Pharmacother, 37 (2000), pp. 1618-1621
[14.]
M.G. Reis, F. Teixeira, G. Costa, M. Guedes, F.P. Silva, M. Tavares.
Pneumonia e Anemia Grave – caso clínico.
Nascer e Crescer, 9 (2000), pp. 246-251
[15.]
T.-C. Yao, I.-J. Hung, T.-H. Jaing, C.-P. Yang.
Pitfalls in the diagnosis of idiopathic pulmonary haemosiderosis.
Arch Dis Child, 86 (2002), pp. 436-438
[16.]
S. Godfrey.
Pulmonary Hemorrhage/Hemoptysis in Children.
Pediatr Pulmonol, 37 (2004), pp. 476-484
Copyright © 2006. Sociedade Portuguesa de Pneumologia
Download PDF
Pulmonology
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?