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        "resumen" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Lung abscesses &#40;LA&#41; carry with them severe clinical and social implications&#46; The authors retrospectively analyse case files from a tertiary hospital&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Admissions from 2000 to 2005 codified as LA were identified&#46; Forty-five patients were males and the mean age was 56&#46;2 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>15&#46;1&#41; years&#46; The average duration of symptoms pre-hospitalisation was 23&#46;0 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>50&#46;2&#41; days&#44; with acute respiratory infection the initial syndrome in 36 patients&#46; Clinical data show LA could have been suspected in 40 patients&#46; Diagnosis was established 8&#46;7 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>11&#46;4&#41; days after admission&#46; A microbial pathogen was recovered in 26 cases&#46; Primary LA was diagnosed in 27 patients&#46; Dental disease and immunodeficiency were the main risk factors&#46; Other co-morbidities were present in 34 patients&#46; After LA diagnosis&#44; intravenous &#40;IV&#41; antibiotic &#40;AB&#41; was prescribed for 16&#46;5 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>10&#46;9&#41; days with mean total AB time 39&#46;2 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>15&#46;7&#41; days&#46; Ten options of AB were used and 23 patients had their initial IV AB changed to a second choice&#46; Six patients needed surgery&#46; Apyrexia was achieved after 6&#46;4 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>6&#46;4&#41; days of treatment&#46; 21 patients had complications and 7 died&#46; The mean length of hospital admission was 27&#46;5 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>16&#46;3&#41; days and 38 patients were called for a follow-up visit&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">These data are generally in accordance with the literature&#46; The high male percentage agrees with the similarly high prevalence of alcoholism and lung neoplasms in males&#46; Key facts to ameliorate in order to improve prognosis and length of hospital admission could be a swifter diagnosis and consensus on the AB treatment&#46;</p>"
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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Abcessos pulmonares &#40;AP&#41; acarretam graves implica&#231;&#245;es cl&#237;nicas e sociais&#46; Os autores analisam retrospectivamente a casu&#237;stica dum hospital terci&#225;rio&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Identificaram-se 60 internamentos por AP ocorridos entre 2000 e 2005&#46; Quarenta e cinco doentes eram homens&#59; a idade m&#233;dia foi 56&#44;2 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>15&#44;1&#41; anos&#46; A dura&#231;&#227;o m&#233;dia dos sintomas de pr&#233;-hospitaliza&#231;&#227;o foi de 23&#44;0 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>50&#44;2&#41; dias&#44; mas a infec&#231;&#227;o respirat&#243;ria aguda foi o modo de apresenta&#231;&#227;o em 36 doentes&#46; Em 40 casos&#44; com base em dados cl&#237;nicos&#44; a suspeita de AP seria elevada&#46; O diagn&#243;stico estabeleceu-se em 8&#44;7 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>11&#44;4&#41; dias ap&#243;s a admiss&#227;o&#46; Identificou-se agente microbiano em 26 casos&#46; Em 27 doentes classificou-se o AP como prim&#225;rio&#46; Mau estado dent&#225;rio e imunodefici&#234;ncia foram os principais factores de risco&#46; Exis- tiam co morbilidades em 34 casos&#46; Ap&#243;s o diagn&#243;stico&#44; todos receberam antibioterapia &#40;AB&#41; intravenosa &#40;IV&#41; em m&#233;dia durante 16&#44;5 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>10&#44;9&#41; dias&#46; A m&#233;dia do tempo global de AB foi de 39&#44;2 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>15&#44;7&#41; dias&#46; Dez op&#231;&#245;es de AB foram usadas e a AB IV inicial alterada em 23 casos&#46; Foi necess&#225;ria cirurgia em 6 doentes&#46; Conseguiu--se apirexia em m&#233;dia ap&#243;s 6&#44;4 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>6&#44;4&#41; dias&#46; Ocorreram complica&#231;&#245;es em 21 doentes&#59; 7 faleceram&#46; A dura&#231;&#227;o m&#233;dia do internamento foi de 27&#44;5 &#40;&#177;<span class="elsevierStyleHsp" style=""></span>16&#44;3&#41; dias e 38 doentes foram convocados para consulta p&#243;s-alta&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Estes dados s&#227;o&#44; em geral&#44; concordantes com a literatura&#46; A elevada percentagem de doentes do sexo masculino coincide com maior preval&#234;ncia do alcoolismo e do carcinoma pulmonar nos homens&#46; Aspectos pertinentes no sentido de melhorar o progn&#243;stico e tempo de internamento poder&#227;o ser a brevidade no diagn&#243;stico e o consenso no tratamento antibi&#243;tico&#46;</p>"
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Vol. 15. Issue 2.
Pages 165-178 (March - April 2009)
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Vol. 15. Issue 2.
Pages 165-178 (March - April 2009)
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Lung abscesses: Review of 60 cases
Abcessos pulmonares: Revisão de 60 casos
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Luísa Magalhães1,
, Diana Valadares1, Júlio R. Oliveira2, Ernestina Reis2,3
1 Interna Complementar de Medicina Interna / Resident, Internal Medicine
2 Assistente Hospitalar de Medicina Interna / Internal Medicine Consultant
3 Hospital Geral de Santo António. Serviço de Medicina 1 (Director de Serviço: Dr. Nelson Rocha) – Unidade D (responsável de unidade: Dra. Ernestina Reis) / Work carried out at Hospital Geral de Santo António. Serviço de Medicina 1 (Department Head: Dr. Nelson Rocha) – Unidade D (Head: Dr. Ernestina Reis)
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Abstract

Lung abscesses (LA) carry with them severe clinical and social implications. The authors retrospectively analyse case files from a tertiary hospital.

Admissions from 2000 to 2005 codified as LA were identified. Forty-five patients were males and the mean age was 56.2 (±15.1) years. The average duration of symptoms pre-hospitalisation was 23.0 (±50.2) days, with acute respiratory infection the initial syndrome in 36 patients. Clinical data show LA could have been suspected in 40 patients. Diagnosis was established 8.7 (±11.4) days after admission. A microbial pathogen was recovered in 26 cases. Primary LA was diagnosed in 27 patients. Dental disease and immunodeficiency were the main risk factors. Other co-morbidities were present in 34 patients. After LA diagnosis, intravenous (IV) antibiotic (AB) was prescribed for 16.5 (±10.9) days with mean total AB time 39.2 (±15.7) days. Ten options of AB were used and 23 patients had their initial IV AB changed to a second choice. Six patients needed surgery. Apyrexia was achieved after 6.4 (±6.4) days of treatment. 21 patients had complications and 7 died. The mean length of hospital admission was 27.5 (±16.3) days and 38 patients were called for a follow-up visit.

These data are generally in accordance with the literature. The high male percentage agrees with the similarly high prevalence of alcoholism and lung neoplasms in males. Key facts to ameliorate in order to improve prognosis and length of hospital admission could be a swifter diagnosis and consensus on the AB treatment.

Key-words:
Lung abscess
necrotising pneumonia
lung infections
Resumo

Abcessos pulmonares (AP) acarretam graves implicações clínicas e sociais. Os autores analisam retrospectivamente a casuística dum hospital terciário.

Identificaram-se 60 internamentos por AP ocorridos entre 2000 e 2005. Quarenta e cinco doentes eram homens; a idade média foi 56,2 (±15,1) anos. A duração média dos sintomas de pré-hospitalização foi de 23,0 (±50,2) dias, mas a infecção respiratória aguda foi o modo de apresentação em 36 doentes. Em 40 casos, com base em dados clínicos, a suspeita de AP seria elevada. O diagnóstico estabeleceu-se em 8,7 (±11,4) dias após a admissão. Identificou-se agente microbiano em 26 casos. Em 27 doentes classificou-se o AP como primário. Mau estado dentário e imunodeficiência foram os principais factores de risco. Exis- tiam co morbilidades em 34 casos. Após o diagnóstico, todos receberam antibioterapia (AB) intravenosa (IV) em média durante 16,5 (±10,9) dias. A média do tempo global de AB foi de 39,2 (±15,7) dias. Dez opções de AB foram usadas e a AB IV inicial alterada em 23 casos. Foi necessária cirurgia em 6 doentes. Conseguiu--se apirexia em média após 6,4 (±6,4) dias. Ocorreram complicações em 21 doentes; 7 faleceram. A duração média do internamento foi de 27,5 (±16,3) dias e 38 doentes foram convocados para consulta pós-alta.

Estes dados são, em geral, concordantes com a literatura. A elevada percentagem de doentes do sexo masculino coincide com maior prevalência do alcoolismo e do carcinoma pulmonar nos homens. Aspectos pertinentes no sentido de melhorar o prognóstico e tempo de internamento poderão ser a brevidade no diagnóstico e o consenso no tratamento antibiótico.

Palavras-chave:
Abcesso pulmonar
pneumonia necrotizante
infecções pulmonares
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Nota: Trabalho apresentado como comunicação oral no 13.° Congresso Nacional de Medicina Interna – 6th European Federation of Internal Medicine Congress, Lisboa, Maio de 2007 / Note: This work was presented as an oral communication at the 13th National Congress of Internal Medicine – 6th European Federation of Internal Medicine Congress, Lisbon, May 2007.

Copyright © 2009. Sociedade Portuguesa de Pneumologia
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