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Vol. 16. Issue 4.
Pages 607-616 (July - August 2010)
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Vol. 16. Issue 4.
Pages 607-616 (July - August 2010)
Artigo de Revisão/Review Article
Open Access
Pneumonia aguda fibrinosa e organizante
Acute fibrinous and organizing pneumonia
Visits
7602
Cláudia Santos1,
Corresponding author
claudiaraimundo80@gmail.com

Serviço de Pneumologia dos Hospitais da Universidade de Coimbra, Director – Dr. Mário Chaves Loureiro, Praceta Prof. Mota Pinto, 3000-075 Coimbra
, Fátima Fradinho2, Alexandra Catarino2
1 Interna Complementar de Pneumologia
2 Assistente Hospitalar de Pneumologia
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Resumo

O padrão histológico de Pneumonia Aguda Fibrinosa e Organizante (AFOP – Acute Fibrinous And Organizing Pneumonia), descrito por Beasley em 2002, caracteriza-se pela existência de fibrina intra-alveolar sob a forma de bolas de fibrina e pneumonia organizativa difusa. A apresentação clínica desta doença intersticial pulmonar pode ser aguda ou subaguda, diferindo no entanto dos outros padrões histológicos habitualmente associados a lesão pulmonar aguda – Lesão Alveolar Difusa (DAD), Pneumonia Organizativa (OP) e Pneumonia Eosinofílica (EP).

A propósito deste tema, os autores fazem uma revisão da literatura e descrevem o caso clínico de um doente de 44 anos, com aspectos imagiológicos e evolução pouco habituais.

Rev Port Pneumol 2010; XVI (4): 607-616

Palavras-chave:
AFOP
bolas de fibrina
pneumonia organizativa
Abstract

The histologic pattern of Acute Fibrinous and Organizing Pneumonia (AFOP), described by Beasley in 2002, is characterized by the existence of intraalveolar fibrin in the form of fibrin “balls” and diffuse organizing pneumonia. Presenting symptoms of this interstitial pulmonary disease can be acute or subacute. However, it differs from the well-recognized histologic patterns of acute pulmonary lesion – Diffuse Alveolar Damage (DAD), Organizing Pneumonia (OP) and Eosinophilic Pneumonia (EP).

The authors carry out a review of the literature concerning this topic and describe the clinical case of a 44-year-old patient with unusual imaging features and outcome.

Rev Port Pneumol 2010; XVI (4): 607-616

Key-word:
AFOP
fibrin balls
organizing pneumonia
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Bibliografia
[1.]
M.B. Beasley, T.J. Franks, J.R. Galvin, et al.
Acute fibrinous and organizing pneumonia: a histologic pattern of lung injury and possible variant of diffuse alveolar damage.
[2.]
Cordeiro C. Robalo.
Airway involvement in interstitial lung disease.
Curr Opin Pulm Med, 12 (2006), pp. 337-341
[3.]
R. Balduin, C. Giacometti, L. Saccarola, et al.
Acute fibrinous and organizing pneumonia in a patient with collagen vascular disease “stigma”.
Sarcoidosis Vasc Diffuse Lung Dis, 24 (2007), pp. 78-80
[4.]
D.M. Hwang, D.W. Chamberlain, S.M. Poutanen, et al.
Pulmonary pathology of severe acute respiratory syndrome in Toronto.
Mod Pathol, 18 (2005), pp. 1-10
[5.]
N. Yokogawa, D.V. Alcid.
Acute fibrinous and organizing pneumonia as a rare presentation of abacavir hypersensitivity reaction.
[6.]
T.S. Vasu, R. Cavallazzi, et al.
A 64-year-old male with fever and persistent lung infiltrate.
Respir Care, 54 (2009), pp. 1263-1265
[7.]
S. Prahalad, J.F. Bohnsack, C.G. Maloney, K.O. Leslie.
Fatal acute fibrinous and organizing pneumonia in a child with juvenile dermatomyositis.
J Pediatr, 146 (2005), pp. 289-292
[8.]
B.C. Kim, R. Servi, B.I. Sucai, R. Ramsey.
Acute lymphoblastic leukemia presenting with an acute fibrinous and organizing pneumonia.
J Resp Dis, 28 (2007), pp. 33-35
[9.]
S.M. Lee, J.J. Park, et al.
Acute fibrinous and organizing pneumonia following hematopoietic stem cell transplantation.
Korean J Intern Med, 24 (2009), pp. 156-159
[10.]
D.R. Cincotta, N.J. Sebire, E. Lim, M.J. Peters.
Fatal acute fibrinous and organizing pneumonia in an infant: the histopathologic variability of acute respiratory distress syndrome.
Pediatr Crit Care Med, 8 (2007), pp. 378-382
[11.]
H. Kobayashi, C. Sugimoto, S. Kanoh, et al.
Acute fibrinous and organizing pneumonia: initial presentation as a solitary nodule.
J Thorac Imaging, 20 (2005), pp. 291-293
[12.]
J.F. Cordier.
Organising pneumonia.
Thorax, 55 (2000), pp. 318-328
[13.]
M. Akira, S. Yamamoto, M. Sakatani.
Bronchiolitis obliterans organizing pneumonia manifesting as multiple large nodules or masses.
[14.]
M. Jarbou, M. Yusof, E. Coberly, et al.
Acute fibrinous and organizing pneumonia.
Chest, 130 (2006), pp. 300S-c301
[15.]
V. Poletti, G.L. Casoni.
Cryptogenic organizing pneumonia or acute fibrinous and organizing pneumonia?.
Eur Respir J, 25 (2005), pp. 1128
[16.]
C. Damas, A. Morais, C.S. Moura, J.A. Marques.
Acute fibrinous and organizing pneumonia.
Rev Port Pneumol, XII (2006), pp. 615-620
[17.]
S. Bhatti, A. Hakeem, et al.
Severe acute fibrinous and organizing pneumonia (AFOP) causing ventilator failure: successful treatment with mycophenolate mofetil and corticosteroids.
Respiratory Medicine, 103 (2009), pp. 1764-1767
Copyright © 2010. Sociedade Portuguesa de Pneumologia/SPP
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