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Vol. 14. Issue 4.
Pages 535-539 (July - August 2008)
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Vol. 14. Issue 4.
Pages 535-539 (July - August 2008)
Caso Clínico/Clinical Case
Open Access
Sarcoma pleomórfico primário do pulmão
Primary pleomorphic sarcoma of the lung
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6797
Marcus da Matta Abreu1, Bruno Marcondes Kozlowski2, Paulo de Biasi Cordeiro3, Aureliano de Sousa4, Marilene F. Nascimento5, Mauro Zamboni6,
Corresponding author
mauro.zamboni@gmail.com

Correspondência: Dr. Mauro Zamboni. Rua Sorocaba 464/302. CEP: 22271-110 – Rio de Janeiro – Brasil.
1 Especializando do S. Cirurgia Torácica Oncológica – HC I – INCA/MS – Rio de Janeiro – Brasil
2 Residente do S. de Cirurgia Torácica Oncológica – HC I – INCA/MS – Rio de Janeiro – RJ
3 Cirurgião de Tórax – S. Cirurgia Torácica Oncológica – HC I – INCA/MS – Rio de Janeiro – Brasil
4 Chefe do S. Cirurgia Torácica Oncológica – HC I – Rio de Janeiro – RJ
5 Patologista e Citopatologista do S. de Anatomia Patológica do INCA
6 Pneumologista do Grupo de Oncologia Torácica do HC I – INCA/MS – Rio de Janeiro – Brasil
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Resumo

A classificação recente da Organização Mundial da Saúde (OMS) para os tumores pulmonares unificou o heterogéneo grupo do carcinoma de não pequenas células (CPNPC), que engloba os sarcomas e os tumores com componentes sarcomatosos, sob a denominação “carcinoma com elementos pleomórficos, sarcomatóides ou sarcomatosos”. Este grupo inclui diferentes entidades, como o carcinoma pleomórfico (CP), o carcinoma de células fusiformes (CCF), carcinoma de células gigantes (CCG), os carcinossarcomas (CS) e o blastoma pulmonar (BP). De uma forma geral, estes tumores são raros e representam 0,1% a 0,4% de todas as neoplasias pulmonares. Ocorrem mais comummente em homens fumadores, com alta carga tabágica, e acomete-os em torno dos 60 anos e comummente tem evolução clínica muito agressiva. Os autores relatam o caso de um doente portador de sarcoma pleomórfico primário pulmonar e revêem a literatura sobre o assunto.

Rev Port Pneumol 2008; XIV (4): 535-539

Palavras-chave:
Neoplasias pulmonares
sarcoma pleomórfico
imunoistoquímica
neoplasia de tecidos conjuntivos e de tecidos moles
Abstract

The World Health Organization (WHO) classification of lung cancers ranks the heterogeneous nonsmall cell lung cancer (N-SCLC) group, encompassing sarcoma or sarcoma-containing tumours under one heading: “carcinomas with pleomorphic, sarcomatoid or sarcomatous elements”.

This group contains entities such as pleomorphic carcinoma (PC), spindle cell carcinoma (SCC), giant cell carcinoma (GCC), carcinosarcoma (CS) and pulmonary blastoma (PB).

These tumors are rare overall, making up approx. 0.1-0.4% of all lung malignancies. They are more commonly found in males who are heavy smokers, diagnosed at the age of 60 on average and follow an aggressive clinical course.

The authors describe the case of a male patient with primary pleomorphic lung sarcoma and also include a review of the literature.

Rev Port Pneumol 2008; XIV (4): 535-539

Key-words:
Lung neoplasms
pleomorphic sarcoma
conective and soft tissue neoplasms
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Copyright © 2008. Sociedade Portuguesa de Pneumologia/SPP
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