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        "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">V&#225;rios estudos demonstram que os doentes com s&#237;ndroma de apneia obstrutiva do sono &#40;SAOS&#41; t&#234;m um risco aumentado de acidentes de via&#231;&#227;o&#46; O objectivo do presente trabalho consistiu em analisar&#44; nestes doentes&#44; se h&#225; diferen&#231;as nos que referem acidentes e&#47; &#47;ou quase acidentes e aqueles que o n&#227;o fazem&#46;</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Material e m&#233;todos</span>&#58; Estudaram-se prospectivamen-te 163 doentes com SAOS &#40;&#237;ndice apneia&#47;hipopneia &#40;IAH&#41;<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>10&#47;h&#41; diagnosticados por polissonografia noc-turna &#40;PSG&#41;&#44; todos condutores de ve&#237;culos&#44; 18&#44;4&#37; do quais profissionais&#46; Na altura da entrevista cl&#237;nica foi inquirido se tinham tido&#44; nos tr&#234;s anos antes acidentes e&#47;ou quase acidentes devido a hipersonia diurna &#40;Grupo II<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>74&#41; ou n&#227;o &#40;Grupo I<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>89&#41;&#46;</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">Estes dois grupos foram comparados quanto a&#58; idade&#44; &#237;ndice de massa corporal &#40;IMC&#41;&#44; escala de sonol&#234;ncia de Epworth &#40;ESE&#41;&#44; PaO<span class="elsevierStyleInf">2</span> e PaCO<span class="elsevierStyleInf">2</span> diurnas&#44; avalia&#231;&#227;o da qualidade de vida pelo inqu&#233;rito <span class="elsevierStyleItalic">Functional Outcomes of Sleep Questionnaire</span> &#40;FOSQ teste&#41; e dados da polissonografia &#8211; tempo total de sono &#40;TTS&#41;&#44; efici&#234;ncia do sono&#44; est&#225;dios do sono&#44; &#237;ndice de microdespertares &#40;IMD&#41;&#44; &#237;ndice de apneia&#47;hipopneia &#40;IAH&#41;&#44; SaO<span class="elsevierStyleInf">2</span> m&#237;nima e m&#233;dia&#44; &#37; tempo SaO<span class="elsevierStyleInf">2</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>90&#37; &#40;T90&#41;&#44; &#237;ndice de dessatura&#231;&#227;o &#40;IDS&#41;&#44; tempo total em apneia&#47;hipopneia &#40;TTOT&#41; &#40;teste <span class="elsevierStyleItalic">t</span> de <span class="elsevierStyleItalic">Studen</span>t&#41;&#46;</p><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Resultados&#58;</span> &#40;Grupo I&#47;Grupo II&#41; idade &#40;anos&#41; &#8211;<span class="elsevierStyleHsp" style=""></span>57&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#44;8 &#47; 54&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#44;9 &#40;ns&#41;&#59; 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XV &#40;3&#41;&#58; 419-431</span></p></span>"
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This allowed patients to be divided into two groups&#44; those who had had road traffic accidents and&#47;or near misses and those who had not&#46; Both were compared as to age&#44; body mass index &#40;BMI&#41;&#44; Epworth Sleepiness Scale &#40;ESS&#41;&#44; daytime PaO<span class="elsevierStyleInf">2</span> and PaCO<span class="elsevierStyleInf">2</span>&#44; Functional Outcomes of Sleep Questionnaire &#40;FOSQ&#41; test and NPSG data&#46; This latter was total sleep time &#40;TTS&#41;&#44; sleep efficiency&#44; sleep stages&#44; arousal index &#40;ARI&#41;&#44; AHI&#44; minimal and average SaO<span class="elsevierStyleInf">2</span>&#44; &#37; of time with SaO<span class="elsevierStyleInf">2</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>90&#37; &#40;T90&#41;&#44; desaturation index &#40;ODI&#41;&#44; total duration of apnoea-hypopnoea &#40;TDAH&#41; &#40;T test&#41;&#46;</p><p id="sp0050" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Results&#58;</span> Group I &#40;no road traffic accidents&#41; No<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>89 patients&#59; group II &#40;road traffic accidents&#41; No<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>74 patients&#46; Age &#40;years&#41; was 57&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#46;8 vs&#46; 54&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#46;9 &#40;ns&#41;&#59; male gender&#44; 75&#37; vs&#46; 78&#46;4&#37;&#59; ESS&#44; 12&#46;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;4 vs&#46; 17&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3 &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41;&#59; BMI&#44; &#40;Kg&#47;m<span class="elsevierStyleSup">2</span>&#41; 36&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#46;1 vs&#46; 35&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#46;3 &#40;ns&#41;&#59; PaO<span class="elsevierStyleInf">2</span> &#40;mmHg&#41;&#44; 76&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#46;4 vs&#46; 78&#46;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>12&#46;6 &#40;ns&#41;&#59; PaCO<span class="elsevierStyleInf">2</span> &#40;mmHg&#41;&#44; 42&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;1 vs&#46; 42&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;7 &#40;ns&#41;&#59; FOSQ&#44; 15&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;1 <span class="elsevierStyleItalic">vs</span>&#46; 12&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;4 &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41;&#46;</p><p id="sp0055" class="elsevierStyleSimplePara elsevierViewall">NPSG data revealed differences only in AHI&#58; 45&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>21&#46;6 <span class="elsevierStyleItalic">vs</span>&#46; 56&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>29&#46;7 &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41; and in TDAH &#40;minutes&#41;&#44; 98&#46;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>63&#46;7 vs&#46; 133&#46;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>83&#46;2 &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;005&#41;&#46;</p><p id="sp0060" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Conclusions&#58;</span> In our experience patients who had road traffic accidents and&#47;or near misses had a more severe OSAS&#44; with higher AHI&#44; excessive daytime sleepiness and lower quality of life&#46;</p><p id="sp0065" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2009&#59; XV &#40;3&#41;&#58; 419-431</span></p></span>"
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Vol. 15. Issue 3.
Pages 419-431 (May - June 2009)
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Vol. 15. Issue 3.
Pages 419-431 (May - June 2009)
Artigo Original/Original Article
Open Access
Síndroma de apneia obstrutiva do sono como causa de acidentes de viação
Obstructive sleep apnoea syndrome as a cause of road traffic accidents
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5155
M. Aguiar1,
Corresponding author
m_aguiar@netcabo.pt

Correspondência/Correspondence to: Margarida Aguiar, Hospital de Santa Maria, Av. Egas Moniz, 1500 Lisboa.
, J. Valença1, M. Felizardo1, F. Caeiro1, S. Moreira1, R. Staats1, A.A. Bugalho de Almeida1
1 Serviço de Pneumologia I, Hospital de Santa Maria, CHLN, EPE, Lisboa / Pulmonology Unit I, Hospital de Santa Maria, CHLN, EPE, Lisboa
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Resumo

Vários estudos demonstram que os doentes com síndroma de apneia obstrutiva do sono (SAOS) têm um risco aumentado de acidentes de viação. O objectivo do presente trabalho consistiu em analisar, nestes doentes, se há diferenças nos que referem acidentes e/ /ou quase acidentes e aqueles que o não fazem.

Material e métodos: Estudaram-se prospectivamen-te 163 doentes com SAOS (índice apneia/hipopneia (IAH)>10/h) diagnosticados por polissonografia noc-turna (PSG), todos condutores de veículos, 18,4% do quais profissionais. Na altura da entrevista clínica foi inquirido se tinham tido, nos três anos antes acidentes e/ou quase acidentes devido a hipersonia diurna (Grupo II=74) ou não (Grupo I=89).

Estes dois grupos foram comparados quanto a: idade, índice de massa corporal (IMC), escala de sonolência de Epworth (ESE), PaO2 e PaCO2 diurnas, avaliação da qualidade de vida pelo inquérito Functional Outcomes of Sleep Questionnaire (FOSQ teste) e dados da polissonografia – tempo total de sono (TTS), eficiência do sono, estádios do sono, índice de microdespertares (IMD), índice de apneia/hipopneia (IAH), SaO2 mínima e média, % tempo SaO2<90% (T90), índice de dessaturação (IDS), tempo total em apneia/hipopneia (TTOT) (teste t de Student).

Resultados: (Grupo I/Grupo II) idade (anos) –57,6±11,8 / 54,7±10,9 (ns); sexo masculino – 75%/ /78,4%; ESE – 12,3±5,4 / 17,6±4,3 (p<0,001); IMC (kg/m2) –36,2±8,1 / 35,6±6,3 (ns); PaO2 (mmHg) – 76,1±11,4 / 78,5±12,6 (ns); PaCO2 (mmHg) – 42,6±5,1 / 42,2±4,7 (ns); FOSQ test – 15,1±3,1/ /12,9±3,4 (p<0,001).

Dos dados da PSG só se encontraram diferenças no IAH – 45,0±21,6 / 56,2±29.7 (p=0,01) e no TTOT (minutos) – 98,5±63,7 / 133,3±83,2 (p=0,005).

Conclusões: Nesta experiência, os doentes com acidentes e/ou quase acidentes tinham uma SAOS mais grave, nomeadamente com maiores IAH e hipersonia diurna, e menor qualidade de vida.

Rev Port Pneumol 2009; XV (3): 419-431

Palavras-chave:
SAOS
acidentes
FOSQ test
Abstract

Several studies have demonstrated that obstructive sleep apnoea syndrome (OSAS) patients have a higher rate of road traffic accidents. Our study aimed to analyse any differences in OSAS patients between those who reported having had road traffic accidents and/or near misses and those who did not.

Methods: We studied 163 patients with OSAS (ap-noea-hypopnoea index (AHI)>10/h) diagnosed using nocturnal polysomnography (NPSG), all drivers, 18.4% of whom drove for a living. Patients were asked at their first clinical interview to self-report road traffic accidents and/or near misses over the past 3 years which had been caused by abnormal daytime drowsiness. This allowed patients to be divided into two groups, those who had had road traffic accidents and/or near misses and those who had not. Both were compared as to age, body mass index (BMI), Epworth Sleepiness Scale (ESS), daytime PaO2 and PaCO2, Functional Outcomes of Sleep Questionnaire (FOSQ) test and NPSG data. This latter was total sleep time (TTS), sleep efficiency, sleep stages, arousal index (ARI), AHI, minimal and average SaO2, % of time with SaO2<90% (T90), desaturation index (ODI), total duration of apnoea-hypopnoea (TDAH) (T test).

Results: Group I (no road traffic accidents) No=89 patients; group II (road traffic accidents) No=74 patients. Age (years) was 57.6±11.8 vs. 54.7±10.9 (ns); male gender, 75% vs. 78.4%; ESS, 12.3±5.4 vs. 17.6±4.3 (p<0.001); BMI, (Kg/m2) 36.2±8.1 vs. 35.6±6.3 (ns); PaO2 (mmHg), 76.1±11.4 vs. 78.5±12.6 (ns); PaCO2 (mmHg), 42.6±5.1 vs. 42.2±4.7 (ns); FOSQ, 15.1±3.1 vs. 12.9±3.4 (p<0.001).

NPSG data revealed differences only in AHI: 45.0±21.6 vs. 56.2±29.7 (p=0.01) and in TDAH (minutes), 98.5±63.7 vs. 133.3±83.2 (p=0,005).

Conclusions: In our experience patients who had road traffic accidents and/or near misses had a more severe OSAS, with higher AHI, excessive daytime sleepiness and lower quality of life.

Rev Port Pneumol 2009; XV (3): 419-431

Key-words:
OSAS
road traffic accidents
FOSQ test
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