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        "resumen" => "<span id="as0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">A s&#237;ndroma hepatopulmonar &#233; uma complica&#231;&#227;o importante da doen&#231;a hep&#225;tica cr&#243;nica&#44; ocorrendo em 16-24&#37; dos doentes&#46; &#201; caracterizada por aumento do gradiente alveolocapilar com ou sem hipoxemia resultante de vasodilata&#231;&#227;o intrapulmonar&#46; O curso da doen&#231;a &#233; progressivo e associado a aumento da morbilidade e mortalidade&#46; N&#227;o existe tratamento m&#233;dico eficaz&#44; sendo o transplante hep&#225;tico a op&#231;&#227;o terap&#234;utica priorit&#225;ria&#46; Como exemplo desta patologia&#44; os autores apresentam o caso cl&#237;nico de um doente&#44; sexo masculino&#44; 39 anos&#44; enviado &#224; consulta de Pneumologia com informa&#231;&#227;o de policitemia secund&#225;ria e dispneia progressiva para esfor&#231;os de m&#233;dia intensidade e cuja investiga&#231;&#227;o permitiu identificar uma s&#237;ndroma hepatopulmonar&#46;</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">Rev Port Pneumol 2010&#59; XVI &#40;4&#41;&#58; 679-685</span></p></span>"
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Vol. 16. Issue 4.
Pages 679-685 (July - August 2010)
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Vol. 16. Issue 4.
Pages 679-685 (July - August 2010)
Caso Clínico/Case Report
Open Access
Síndroma hepatopulmonar: Relato de um caso clínico e revisão do tema
Hepatopulmonary syndrome: Case report and literature review
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Michele De Santis1,
Corresponding author
iperpicchio76@hotmail.com

Serviço de Pneumologia, Centro Hospitalar de Coimbra, (Director: Dr. Fernando Barata), Quinta dos Vales, São Martinho do Bispo, 3046 -853 Coimbra
, Luis Vaz Rodrigues1, Fernando Matos2
1 Interno de Pneumologia, Centro Hospitalar de Coimbra, EPE
2 Assistente Graduado em Pneumologia, Centro Hospitalar de Coimbra, EPE
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A síndroma hepatopulmonar é uma complicação importante da doença hepática crónica, ocorrendo em 16-24% dos doentes. É caracterizada por aumento do gradiente alveolocapilar com ou sem hipoxemia resultante de vasodilatação intrapulmonar. O curso da doença é progressivo e associado a aumento da morbilidade e mortalidade. Não existe tratamento médico eficaz, sendo o transplante hepático a opção terapêutica prioritária. Como exemplo desta patologia, os autores apresentam o caso clínico de um doente, sexo masculino, 39 anos, enviado à consulta de Pneumologia com informação de policitemia secundária e dispneia progressiva para esforços de média intensidade e cuja investigação permitiu identificar uma síndroma hepatopulmonar.

Rev Port Pneumol 2010; XVI (4): 679-685

Palavras-chaves:
Síndroma hepatopulmonar
hipoxemia
hepatopatia
transplante hepático
Abstract

Hepatopulmonary syndrome is an important complication of chronic liver disease occurring in 1624% of patients. It is characterized by an increase in alveolar-capillary gradient, with or without hypoxemia, due to intrapulmonary vasodilatation. The course of the disease is progressive and associated with increased morbidity and mortality. There is no effective medical treatment and liver transplant is a priority. To exemplify the authors present the case of a 39 year-old male patient sent to the Pulmonology outpatient clinic and presenting with secondary polycythemia and progressive exertional dyspnoea. Clinical investigation identified a hepatopulmonary syndrome.

Rev Port Pneumol 2010; XVI (4): 679-685

Key-words:
Hepatopulmonary syndrome
hypoxemia
hepatophaty
hepatic transplant
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